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71. 发明申请

US20120157856A1 HEART FAILURE DETECTION WITH A SEQUENTIAL CLASSIFIER 审中-公开
标题翻译：心脏故障检测与序列分类器
公开(公告)号：US20120157856A1
公开(公告)日：2012-06-21
申请号：US13306343
申请日：2011-11-29
申请人： Qi An , Yi Zhang
发明人： Qi An , Yi Zhang
IPC分类号： A61B5/02 , A61B5/053 , A61B5/0205
CPC分类号： A61B5/0816 , A61B5/0205 , A61B5/024 , A61B5/0538 , A61B7/006 , A61B7/04 , G06F19/3418 , G06F19/3481 , G16H50/20
摘要： A system and method for automatically analyzing heart failure in a patient, including collecting physiological data from a patient using at least a first sensor and a second sensor to collect two or more sensor measurements, and calculating a first composite value based on at least a first sensor measurement wherein the first composite value is an indication of a likelihood that the patient's heart failure status has changed. If the first composite value is outside of a first specified range, then a second composite value is calculated based on at least a second sensor measurement, wherein the second composite value is an indication of a likelihood that the patient's heart failure status has changed. If the second composite value is outside of a second specified range, then an alert of change in heart failure status is generated.
摘要翻译：一种用于自动分析患者心力衰竭的系统和方法，包括使用至少第一传感器和第二传感器从患者收集生理数据以收集两个或更多个传感器测量值，以及基于至少第一传感器测量，其中第一复合值是患者的心力衰竭状态已经改变的可能性的指示。如果第一复合值在第一指定范围之外，则基于至少第二传感器测量来计算第二复合值，其中第二复合值是患者的心力衰竭状态已经改变的可能性的指示。如果第二个复合值超出第二个指定范围，则会产生心力衰竭状态变化警报。

72. 发明申请

US20120004565A1 ISCHEMIA DETECTION USING A HEART SOUND SENSOR 有权
标题翻译：使用心音传感器进行ISCHEMIA检测
公开(公告)号：US20120004565A1
公开(公告)日：2012-01-05
申请号：US13231152
申请日：2011-09-13
申请人： Yi Zhang , Richard Fogoros , Carlos Haro , Yousufali Dalal , Marina V. Brockway , Krzysztof Z. Siejko
发明人： Yi Zhang , Richard Fogoros , Carlos Haro , Yousufali Dalal , Marina V. Brockway , Krzysztof Z. Siejko
IPC分类号： A61B5/02 , A61B5/0205
CPC分类号： A61N1/3627 , A61B5/0031 , A61B5/024 , A61B5/0452 , A61B5/0456 , A61B7/04 , A61N1/36578 , A61N1/395
摘要： A system comprising an implantable medical device (IMD) includes an implantable heart sound sensor to produce an electrical signal representative of at least one heart sound. The heart sound is associated with mechanical activity of a patient's heart. Additionally, the IMD includes a heart sound sensor interface circuit coupled to the heart sound sensor to produce a heart sound signal, and a signal analyzer circuit coupled to the heart sound sensor interface circuit. The signal analyzer circuit measures a baseline heart sound signal, and deems that an ischemic event has occurred using, among other things, a measured subsequent change in the heart sound signal from the established baseline heart sound signal.
摘要翻译：包括可植入医疗装置（IMD）的系统包括可植入心音传感器，以产生代表至少一个心音的电信号。心脏声音与患者心脏的机械活动有关。另外，IMD包括耦合到心脏声音传感器以产生心脏声音信号的心脏声音传感器接口电路，以及耦合到心脏声音传感器接口电路的信号分析器电路。信号分析器电路测量基线心音信号，并且认为已经发生了缺血事件，其中使用来自已建立的基线心音信号的心音信号的测量后续变化。

73. 发明授权

US08075889B2 Antibody molecules having specificity for human IL-6 有权
标题翻译：对人IL-6具有特异性的抗体分子
公开(公告)号：US08075889B2
公开(公告)日：2011-12-13
申请号：US11608408
申请日：2006-12-08
申请人： Richard Evan Gelinas , Mitra Choudhury Singhal , Yi Zhang , Andrew George Popplewell , Ralph Adams
发明人： Richard Evan Gelinas , Mitra Choudhury Singhal , Yi Zhang , Andrew George Popplewell , Ralph Adams
IPC分类号： A61K39/00 , A61K39/395
CPC分类号： A61K39/3955 , A61K2039/505 , C07K16/248 , C07K2316/96 , C07K2317/24 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C12N15/11
摘要： The invention relates to antibody molecules having specificity for antigenic determinants of IL-6, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
摘要翻译：本发明涉及对IL-6的抗原决定簇具有特异性的抗体分子，抗体分子的治疗用途以及产生所述抗体分子的方法。

74. 发明申请

US20110301530A1 MONITORING OF CHRONOBIOLOGICAL RHYTHMS FOR DISEASE AND DRUG MANAGEMENT USING ONE OR MORE IMPLANTABLE DEVICE 有权
标题翻译：使用一个或多个可植入装置监测疾病和药物管理的血液生殖系统
公开(公告)号：US20110301530A1
公开(公告)日：2011-12-08
申请号：US13209938
申请日：2011-08-15
申请人： Yi Zhang , John D. Hatlestad , Gerrard M. Carlson , Yousufali Dalal , Marina V. Brockway , Kent Lee , Richard O. Kuenzler , Carlos Haro , Krzysztof Z. Siejko , Abhilash Patangay
发明人： Yi Zhang , John D. Hatlestad , Gerrard M. Carlson , Yousufali Dalal , Marina V. Brockway , Kent Lee , Richard O. Kuenzler , Carlos Haro , Krzysztof Z. Siejko , Abhilash Patangay
IPC分类号： A61N1/08 , A61N1/365 , A61M5/142
CPC分类号： A61M5/1723 , A61B5/02055 , A61B5/0215 , A61B5/024 , A61B5/02405 , A61B5/053 , A61B5/0816 , A61B5/1116 , A61B5/686 , A61B5/7275 , A61N1/36114 , A61N1/36135 , A61N1/3621 , A61N1/365 , A61N1/36585 , G06F19/00
摘要： The health state of a subject is automatically evaluated or predicted using at least one implantable device. In varying examples, the health state is determined by sensing or receiving information about at least one physiological process having a circadian rhythm whose presence, absence, or baseline change is associated with impending disease, and comparing such rhythm to baseline circadian rhythm prediction criteria. Other chronobiological rhythms beside circadian may also be used. The baseline prediction criteria may be derived using one or more past physiological process observation of the subject or population of subjects in a non-disease health state. The prediction processing may be performed by the at least one implantable device or by an external device in communication with the implantable device. Systems and methods for invoking a therapy in response to the health state, such as to prevent or minimize the consequences of predicted impending heart failure, are also discussed.
摘要翻译：使用至少一个可植入装置自动评价或预测受试者的健康状况。在不同的实施例中，通过感测或接收关于至少一个具有昼夜节律的生理过程的信息来确定健康状况，所述生理过程的存在，不存在或基线变化与即将发生的疾病相关联，并将该节律与基线昼夜节律预测标准进行比较。也可以使用昼夜节律以外的其他时间生理节律。可以使用在非疾病健康状态下的受试者或受试者群体的一个或多个过去的生理过程观察来导出基线预测标准。预测处理可以由至少一个可植入装置或与可植入装置通信的外部装置执行。还讨论了响应于健康状态调用疗法的系统和方法，例如预防或最小化预期的即将到来的心力衰竭的后果。

75. 发明授权

US08059535B2 Method and core router for delaying burst 有权
标题翻译：方法和核心路由器延迟突发
公开(公告)号：US08059535B2
公开(公告)日：2011-11-15
申请号：US12469286
申请日：2009-05-20
申请人： Sheng Wang , Yulei Qi , Du Xu , Shizhong Xu , Yi Zhang
发明人： Sheng Wang , Yulei Qi , Du Xu , Shizhong Xu , Yi Zhang
IPC分类号： G01R31/08
CPC分类号： H04L47/10 , H04L47/11 , H04L47/17 , H04L47/32 , H04Q11/0066 , H04Q2011/002 , H04Q2011/0045 , H04Q2011/005 , H04Q2011/0064
摘要： A method and a core router for implementing forward delay for bursts are disclosed. The core router configured with an FDL performs proactive delay processing for the burst to be overlapped after predicting that the burst will be overlapped on the link to be protected, thus reducing the probability of burst conflict on the downstream link to be protected. After finding that burst conflict will occur on the output port of the core router at a future moment, the core router sends a burst delay request to the upstream core router, requesting the upstream core router that has an FDL and the delay capability to delay the burst. Therefore, the FDL configured in the network is brought into full play, and the probability of burst conflict is reduced.
摘要翻译：公开了一种用于实现突发的前向延迟的方法和核心路由器。配置有FDL的核心路由器在预测突发将被重叠在待保护的链路上之后对突发进行主动延迟处理以重叠，从而降低要被保护的下游链路上的突发冲突的可能性。在未来发现核心路由器的输出端口发生突发冲突后，核心路由器向上游核心路由器发送突发延迟请求，请求具有FDL的上游核心路由器和延迟能力延迟爆裂。因此，网络中配置的FDL充分发挥，突发冲突的可能性降低。

76. 发明授权

US08050284B2 Method, device and communication equipment for controlling a burst assembly 有权
标题翻译：用于控制突发组件的方法，设备和通信设备
公开(公告)号：US08050284B2
公开(公告)日：2011-11-01
申请号：US12464521
申请日：2009-05-12
申请人： Lu Zhao , Sheng Wang , Shizhong Xu , Yi Zhang
发明人： Lu Zhao , Sheng Wang , Shizhong Xu , Yi Zhang
IPC分类号： H04L12/56
CPC分类号： H04L47/10 , H04L47/22 , H04L47/283 , H04L47/30 , H04L49/90 , H04L69/28 , H04Q11/0066 , H04Q2011/0064
摘要： A method for controlling burst assembly, device, and communication equipment thereof are provided. In the present invention, an assembly time and a predetermined time threshold are compared to determine a load change in a cache queue. If the load is increased or decreased suddenly, a length threshold is directly increased or decreased. If the load is to be increased, the length threshold is randomly increased according to a certain probability. If the load is to be decreased, the length threshold is randomly decreased according to a certain probability. If the load is in a normal state, the length threshold is maintained. Therefore, the length threshold is dynamically adjusted with the load change. The method and device provided by the present invention ensure an end-to-end (E2E) delay of the services and optimize the network performance.
摘要翻译：提供了一种用于控制突发组件，设备和通信设备的方法。在本发明中，比较组装时间和预定时间阈值以确定高速缓存队列中的负载变化。如果负载突然增加或减小，则直接增加或减少长度阈值。如果要增加负载，则根据一定的概率，长度阈值是随机增加的。如果要降低负载，则根据一定的概率，长度阈值是随机减小的。如果负载处于正常状态，则保持长度阈值。因此，根据负载变化动态调整长度阈值。本发明提供的方法和设备确保服务的端到端（E2E）延迟并优化网络性能。

77. 发明申请

US20110220915A1 Off-Axis Silicon Carbide Substrates 有权
标题翻译：离轴碳化硅基板
公开(公告)号：US20110220915A1
公开(公告)日：2011-09-15
申请号：US12966753
申请日：2010-12-13
申请人： James Edgar , Michael Dudley , Martin Kuball , Yi Zhang , Guan Wang , Hui Chen , Yu Zhang
发明人： James Edgar , Michael Dudley , Martin Kuball , Yi Zhang , Guan Wang , Hui Chen , Yu Zhang
IPC分类号： H01L29/24 , C30B25/02 , C30B25/18 , H01L29/22 , H01L29/04 , H01L21/20
CPC分类号： H01L29/045 , C30B25/18 , H01L21/0237 , H01L21/02378 , H01L21/02433 , H01L21/02521 , H01L21/02529 , H01L21/02658
摘要： A method of epitaxial growth of a material on a crystalline substrate includes selecting a substrate having a crystal plane that includes a plurality of terraces with step risers that join adjacent terraces. Each terrace of the plurality or terraces presents a lattice constant that substantially matches a lattice constant of the material, and each step riser presents a step height and offset that is consistent with portions of the material nucleating on adjacent terraces being in substantial crystalline match at the step riser. The method also includes preparing a substrate by exposing the crystal plane; and epitaxially growing the material on the substrate such that the portions of the material nucleating on adjacent terraces merge into a single crystal lattice without defects at the step risers.
摘要翻译：在晶体衬底上外延生长材料的方法包括：选择具有晶面的衬底，所述晶体平面包括多个梯田，其具有连接相邻梯田的台阶梯。多个或梯田中的每个平台呈现基本匹配材料的晶格常数的晶格常数，并且每个梯级提升层具有台阶高度和偏移，其与在相邻台阶上成核的材料的部分一致，一步提升。该方法还包括通过暴露晶面制备衬底; 并且在衬底上外延生长材料，使得在相邻梯田上成核的材料部分合并成单层晶格，而在台阶立管上没有缺陷。

78. 发明授权

US07974403B2 Method and system for called party to provide indication information to calling party 有权
标题翻译：被叫方向主叫方提供指示信息的方法和系统
公开(公告)号：US07974403B2
公开(公告)日：2011-07-05
申请号：US11505108
申请日：2006-08-15
申请人： Jun Wang , Yan Li , Yi Zhang , Jianfeng Liu
发明人： Jun Wang , Yan Li , Yi Zhang , Jianfeng Liu
IPC分类号： H04M1/00
CPC分类号： H04M3/4211 , H04M1/57 , H04M1/72519 , H04M3/42017 , H04M3/42059 , H04M3/42161 , H04M3/42382 , H04M3/436 , H04M2203/2011 , H04M2203/654
摘要： The present invention discloses a method for a called party to provide indication information for a calling party. The method includes the steps of: presetting the indication information to be provided to the calling party at the called party; before the called party answers the call in the connection procedure between the calling party and the called party, the network side obtaining the preset indication information from the called party and sending the indication information to the calling party. Accordingly, the present invention discloses a system for a called party to provide the indication information to a calling party. The present invention makes it possible that the called party flexibly selects the indication information to be provided to the calling party and the problem that only the indication information in the indication information database can be provided is avoided.
摘要翻译：本发明公开了一种被叫方为主叫方提供指示信息的方法。该方法包括以下步骤：在被叫方预置提供给主叫方的指示信息; 在被叫方在主叫方与被叫方之间的连接过程中应答呼叫时，网络侧从被叫方获取预设指示信息，并向主叫方发送指示信息。因此，本发明公开了一种被叫方向主叫方提供指示信息的系统。本发明使得被叫方能够灵活地选择要提供给主叫方的指示信息，并且避免了只能提供指示信息数据库中的指示信息的问题。

79. 发明授权

US07968066B2 Method for production of alkali metal chromates 有权
标题翻译：碱金属铬酸盐的生产方法
公开(公告)号：US07968066B2
公开(公告)日：2011-06-28
申请号：US10549594
申请日：2003-03-19
申请人： Zuohu Li , Yi Zhang , Shili Zheng , Tao Qi , Huiquan Li , Hongbin Xu , Zhikuan Wang
发明人： Zuohu Li , Yi Zhang , Shili Zheng , Tao Qi , Huiquan Li , Hongbin Xu , Zhikuan Wang
IPC分类号： C01G37/14
CPC分类号： C01G37/14
摘要： This invention relates to a method for producing chromates, especially for producing alkali metal chromates. The method comprises following steps: the obtaining of a mixture of alkali metal hydroxide, alkali metal chromate, and ferrous residue after the reaction of chromite ore with an oxidant in the reactor in the presence of molten salt or in aqueous solution of alkali metal hydroxide, the obtaining of a leaching slurry by leaching the reaction products with aqueous solution of alkali metal hydroxide, the separating of the primary chromate product from the leaching slurry, the obtaining of pure chromate crystal by purifying the primary chromate product. Both the primary chromate product and the pure chromate crystal can be used as the raw materials to manufacture other chromium compounds. Compared with the currently-used roasting method, the method has the advantages of decreasing the reaction temperature by about 700° C., of improving the chromium recovery rate up to nearly 100%, of minimizing the amount of the ferrous residue by not adding calcium-containing auxiliaries, and of completely eliminating the disposal problem of the chromium-containing residue and the environmental pollution due to the addition of calcium-containing auxiliaries, by using ferrous residue as the raw materials for other industries after extraction of magnesium.
摘要翻译：本发明涉及生产铬酸盐的方法，特别是生产碱金属铬酸盐。该方法包括以下步骤：在熔融盐存在下或在碱金属氢氧化物的水溶液中，在铬酸铁矿与氧化剂反应后，获得碱金属氢氧化物，碱金属铬酸盐和亚铁残留物的混合物，通过将碱金属氢氧化物水溶液浸出反应产物，从浸出浆中分离出一次铬酸盐产物，通过纯化一次铬酸盐产物得到纯的铬酸盐晶体，从而获得浸出浆料。主要的铬酸盐产物和纯铬酸盐晶体都可以用作制造其他铬化合物的原料。与目前使用的焙烧方法相比，该方法具有将反应温度降低约700℃，将铬回收率提高至近100％的优点，通过不添加钙来最小化亚铁残留量并且完全消除了含铬残渣的处理问题，以及由于添加含钙助剂而导致的环境污染，在提取镁后，以铁渣作为其他工业的原料。

80. 发明申请

US20110144709A1 METHOD AND APPARATUS FOR CARDIAC PROTECTION PACING 有权
标题翻译：心脏保护剂的方法和装置
公开(公告)号：US20110144709A1
公开(公告)日：2011-06-16
申请号：US13029631
申请日：2011-02-17
申请人： Tamara Colette Baynham , Yi Zhang , Joseph M. Pastore
发明人： Tamara Colette Baynham , Yi Zhang , Joseph M. Pastore
IPC分类号： A61N1/365
CPC分类号： A61N1/36514 , A61N1/3621 , A61N1/36521 , A61N1/36557 , A61N1/36564 , A61N1/36578 , A61N1/36585
摘要： A pacing system delivers cardiac protection pacing to protect the heart from injuries associated with ischemic events. The pacing system detects an ischemic event and, in response, initiates one or more cardiac protection pacing sequences each including alternative pacing and non-pacing periods. In one embodiment, the pacing system initiates cardiac protection pacing sequences including at least one postconditioning sequence to protect the heart from a detected ischemic event and a plurality prophylactic preconditioning sequences to protect the heart from probable future ischemic events.
摘要翻译：起搏系统提供心脏保护起搏，以保护心脏免受与缺血事件相关的损伤。起搏系统检测缺血事件，并作为响应启动一个或多个心脏保护起搏序列，每个起搏序列包括替代起搏和非起搏期。在一个实施例中，起搏系统启动心脏保护起搏序列，包括至少一个后处理序列以保护心脏免受所检测的缺血事件和多个预防性预处理序列，以保护心脏免受可能的未来缺血事件。

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