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71. 发明申请

WO2005072445A3 APPARATUS AND METHOD FOR FACILITATING TREATMENT OF TISSUE VIA IMPROVED DELIVERY OF ENERGY BASED AND NON-ENERGY BASED MODALITIES 审中-公开
标题翻译：通过改进基于能源和非能源的模式的交付来促进组织治疗的装置和方法
公开(公告)号：WO2005072445A3
公开(公告)日：2009-03-26
申请号：PCT/US2005003140
申请日：2005-01-28
申请人： NEOGUIDE SYSTEMS INC , BELSON AMIR , OHLINE MATT
发明人： BELSON AMIR , OHLINE MATT
IPC分类号： A61B1/06 , A61B1/005 , A61B1/05 , A61B1/31 , A61B17/00 , A61B18/02 , A61B18/14 , A61B18/22 , G02B23/24
CPC分类号： A61B1/0055 , A61B1/0051 , A61B1/0052 , A61B1/0053 , A61B1/0058 , A61B1/0125 , A61B1/018 , A61B1/05 , A61B1/31 , A61B18/02 , A61B18/1492 , A61B18/22 , A61B2017/00296 , A61B2017/003 , A61B2018/00351 , A61B2018/00446 , A61B2018/0212 , A61B2034/301 , G02B23/2469 , G02B23/2476 , G02B23/2484
摘要： Methods and apparatus for accessing and treating regions of the body are disclosed herein. Using an endoscopic device having an automatically controllable proximal and a selectively steerable distal portion, the device generally may be advanced into the body through an opening. The distal portion is selectively steered to assume a selected curve along a desired path within the body which avoids contact with tissue while the proximal portion is automatically controlled to assume the selected curve of the distal portion. The endoscopic device can then be used for accessing various regions of the body which are typically difficult to access and treat through conventional surgical techniques because the device is unconstrained by "straight-line" requirements. Various applications can include accessing regions of the brain, thoracic cavity, including regions within the heart, peritoneal cavity, etc., which are difficult to reach using conventional surgical procedures.
摘要翻译：本文公开了用于进入和处理身体区域的方法和装置。使用具有自动控制的近侧和可选择性可操纵的远端部分的内窥镜装置，该装置通常可以通过开口进入身体。远侧部分被选择性地转向以沿着主体内的期望路径呈现出选择的曲线，其避免与组织的接触，而近端部分被自动控制以呈现远端部分的选定曲线。然后可以使用内窥镜装置来访问身体的各个区域，这些区域通常难以通过常规手术技术进行治疗，因为该装置不受“直线”要求的约束。各种应用可以包括进入脑，胸腔的区域，包括心脏内的区域，腹膜腔等，其使用常规的外科手术难以达到。

72. 发明申请

WO2007137208A2 METHODS AND APPARATUS FOR DISPLAYING THREE-DIMENSIONAL ORIENTATION OF A STEERABLE DISTAL TIP OF AN ENDOSCOPE 审中-公开
标题翻译：用于显示内窥镜可切割远端的三维方位的方法和装置
公开(公告)号：WO2007137208A2
公开(公告)日：2007-11-29
申请号：PCT/US2007/069315
申请日：2007-05-18
申请人： NEOGUIDE SYSTEMS, INC. , ENO, Robert , BELSON, Amir , BLAHA, David , WOODLEY, Bruce, Robert
发明人： ENO, Robert , BELSON, Amir , BLAHA, David , WOODLEY, Bruce, Robert
IPC分类号： A61B1/00 , A61B1/04
CPC分类号： A61B5/7435 , A61B1/00039 , A61B1/00045 , A61B1/0053 , A61B1/0055 , A61B1/0057 , A61B1/008 , A61B5/06 , A61B5/743
摘要： The present invention relates, generally, to reporting the approximate three- dimensional orientation of the steerable distal portion of an endoscope to the user of the endoscope. More particularly, the present invention relates to a system and method for providing the endoscope-user a display from which to more easily determine the approximate three-dimensional orientation of the steerable distal portion of the endoscope, thereby facilitating navigation of the endoscope. The present invention also relates to a system and method for limiting the amount the steerable distal portion can bend overall to reduce or eliminate the user's ability to over-retroflex the steerable distal portion of the endoscope.
摘要翻译：通常，本发明涉及将内窥镜的可转向远端部分的近似三维取向报告给内窥镜的使用者。更具体地说，本发明涉及一种用于向内窥镜用户提供显示器的系统和方法，从而更容易地确定内窥镜的可转向远端部分的近似三维取向，从而便于内窥镜的导航。本发明还涉及一种用于限制可转向远侧部分可以整体弯曲的量的系统和方法，以减少或消除使用者对内窥镜的可转向远侧部分的过度逆转的能力。

73. 发明申请

WO2007033379A2 METHODS AND APPARATUS FOR PERFORMING TRANSLUMINAL AND OTHER PROCEDURES 审中-公开
标题翻译：用于执行透镜和其他程序的方法和装置
公开(公告)号：WO2007033379A2
公开(公告)日：2007-03-22
申请号：PCT/US2006/036140
申请日：2006-09-14
申请人： NEOGUIDE SYSTEMS, INC. , BELSON, Amir
发明人： BELSON, Amir
IPC分类号： A61B1/00
CPC分类号： A61B17/0057 , A61B1/00087 , A61B1/00128 , A61B1/00154 , A61B1/00177 , A61B1/0055 , A61B1/0057 , A61B1/008 , A61B1/01 , A61B1/015 , A61B1/0615 , A61B1/31 , A61B1/3132 , A61B5/0071 , A61B5/0073 , A61B5/0075 , A61B5/0084 , A61B5/064 , A61B5/418 , A61B17/0401 , A61B17/064 , A61B17/1114 , A61B17/115 , A61B17/1155 , A61B17/1285 , A61B17/3462 , A61B17/3476 , A61B17/3478 , A61B34/20 , A61B34/70 , A61B34/71 , A61B90/36 , A61B90/361 , A61B90/50 , A61B2017/00106 , A61B2017/00278 , A61B2017/00296 , A61B2017/003 , A61B2017/00331 , A61B2017/00336 , A61B2017/00398 , A61B2017/00482 , A61B2017/00561 , A61B2017/00575 , A61B2017/0069 , A61B2017/00871 , A61B2017/0641 , A61B2017/0647 , A61B2017/22077 , A61B2017/306 , A61B2017/3419 , A61B2017/3445 , A61B2017/3447 , A61B2017/347 , A61B2017/3484 , A61B2017/3486 , A61B2017/3488 , A61B2017/349 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/2055 , A61B2034/2059 , A61B2034/2063 , A61B2034/256 , A61B2034/301 , A61B2034/741 , A61B2034/742 , A61B2090/037 , A61B2090/062 , A61B2090/306 , A61B2090/309 , A61B2090/364 , A61B2090/508 , A61M13/003 , A61M2205/0266 , A61M2205/0272 , A61M2205/0277 , A61M2205/0283
摘要： The invention is directed to an apparatus for use in a transluminal procedure. The apparatus, comprising, for example, a housing having a guide lumen and a seal proximal to a distal end of the housing that extends across and completely seals the guide lumen; a fixation element in the housing and adapted to secure the distal end of the housing to tissue; and a channel extending through the side wall of the housing having an outlet in communication with the lumen distal of the seal. Methods are also provided. For example, a method includes, performing a transluminal procedure by: securing a datum and position indicator to a wall of a target lumen; forming an opening in the wall; advancing an instrument through the opening; and tracking the advancement of the instrument using the datum and position indicator.
摘要翻译：本发明涉及一种用于腔内程序的装置。该装置包括例如具有引导腔和壳体近端的密封件的壳体，其延伸穿过并完全密封引导内腔; 壳体中的固定元件，并且适于将外壳的远端固定到组织上; 并且延伸穿过所述壳体的侧壁的通道具有与所述密封件的远侧的所述腔连通的出口。还提供了方法。例如，一种方法包括：通过以下步骤执行经验程序：将基准和位置指示器固定到目标管腔的壁上; 在墙壁上形成一个开口; 通过开口推进仪器; 并使用基准和位置指示器跟踪仪器的进度。

74. 发明申请

WO2004084702A3 METHOD AND APPARATUS FOR TRACKING INSERTION DEPTH 审中-公开
标题翻译：跟踪插入深度的方法和装置
公开(公告)号：WO2004084702A3
公开(公告)日：2005-05-06
申请号：PCT/US2004006939
申请日：2004-03-05
申请人： NEOGUIDE SYSTEMS INC , WHITIN KATHERINE , OHLINE ROBERT M , BELSON AMIR , ROTH ALEX , ARNE LAWRENCE W
发明人： WHITIN KATHERINE , OHLINE ROBERT M , BELSON AMIR , ROTH ALEX , ARNE LAWRENCE W
IPC分类号： A61B1/31 , A61B5/06 , A61B5/107 , A61B5/00
CPC分类号： A61B5/068 , A61B1/31 , A61B5/064 , A61B5/1076 , A61B6/12
摘要： Datum (96) may be positioned externally of patient (18) adjacent to an opening into a body cavity, eg anus (20) for colonoscopic procedures. Datum (96) may have a sensor reader (98) located next to the opening (100) which maybe usd as a guide for passage of the endoscope (92) therethrough. Endoscope (92) is configured with multiple tags (94) eg sensors or transponders located along its length in order to provide real-time positional information.
摘要翻译：基准面（96）可以位于患者（18）外侧，邻近开口进入体腔，例如用于结肠镜检查的肛门（20）。基准（96）可以具有位于开口（100）旁边的传感器读取器（98），其可以作为用于内窥镜（92）通过的引导件。内窥镜（92）配置有多个标签（94），例如沿其长度定位的传感器或应答器，以便提供实时位置信息。

75. 发明申请

WO2004049905A3 ENDOSCOPE WITH ADJACENTLY POSITIONED GUIDING APPARATUS 审中-公开
标题翻译：内窥镜与定位指导装置
公开(公告)号：WO2004049905A3
公开(公告)日：2005-03-31
申请号：PCT/US0337778
申请日：2003-11-26
申请人： NEOGUIDE SYSTEMS INC , TARTAGLIA JOSEPH M , KELLER WADE A , BELSON AMIR , RATCHFORD ARTHUR R
发明人： TARTAGLIA JOSEPH M , KELLER WADE A , BELSON AMIR , RATCHFORD ARTHUR R
IPC分类号： G02B23/24 , A61B20060101 , A61B1/00 , A61B1/005 , A61B1/008 , A61B1/01 , A61B1/04 , A61B1/31
CPC分类号： A61B1/00073 , A61B1/0014 , A61B1/00147 , A61B1/0053 , A61B1/0055 , A61B1/008 , A61B1/01 , A61B1/07 , A61B1/31 , A61B5/065 , A61B2017/00323 , A61B2034/301 , A61B2034/741 , A61B2034/742
摘要： An endoscope with guiding apparatus is provided. The endoscope has an elongate body with a steerable distal portion, an automatically controlled portion, a flexible and passively manipulated proximal portion, and an externally controlled and manipulatable guiding apparatus. The guiding apparatus may be positioned within the endoscope or may be positioned adjacent to the endoscope. An interlocking device is provided to slidably interlock the guiding apparatus and the endoscope. When the guide is in a flexible state, it can conform to a curve or path defined by the steerable distal portion and the automatically controlled portion. The guide can be then be selectively rigidized to assume that curve or path. Once rigidized, the endoscope can be advanced along the guide in a monorail or "piggy-back" fashion so that the flexible proximal portion follows the curve held by the guide until the endoscope reaches a next point of curvature within a body lumen.
摘要翻译：提供具有引导装置的内窥镜。内窥镜具有细长主体，其具有可转向的远端部分，自动控制部分，柔性和被动操纵的近端部分以及外部控制和可操纵的引导装置。引导装置可以定位在内窥镜内，或者可以定位成与内窥镜相邻。联锁装置设置成可滑动地联动引导装置和内窥镜。当引导件处于柔性状态时，其可以符合由可转向远端部分和自动控制部分限定的曲线或路径。然后可以将引导件选择性地刚性化以假定该曲线或路径。一旦刚性化，内窥镜可以沿着导轨以单轨或“背部”方式前进，使得柔性近端部分遵循由引导件保持的曲线，直到内窥镜到达体腔内的下一个曲率点。

76. 发明申请

WO2005018428A3 ACTIVATED POLYMER ARTICULATED INSTRUMENTS AND METHODS OF INSERTION 审中-公开
公开(公告)号：WO2005018428A3
公开(公告)日：2005-03-03
申请号：PCT/US2004/026948
申请日：2004-08-20
申请人： NEOGUIDE SYSTEMS, INC. , BELSON, Amir , OHLINE, Robert, Matthew
发明人： BELSON, Amir , OHLINE, Robert, Matthew
IPC分类号： A61B1/00
摘要： An electro-polymeric articulated endoscope (90) and method of insertion are described herein. A steerable endoscope (90) having a segmented, elongated body (96, 98, 100) with a manually or selectively steerable distal portion (102) and an automatically controlled proximal portion can be articulated by electro-polymeric materials. These materials are configured to mechanically contract or expand in the presence of a stimulus, such as an electrical field. Adjacent segments of the endoscope (90) can be articulated using the electro-polymeric material by inducing relative differences in size or length of the material when placed near or around the outer periphery along a portion of the endoscope.

77. 发明申请

WO2004084702A9 METHOD AND APPARATUS FOR TRACKING INSERTION DEPTH 审中-公开
标题翻译：跟踪插入深度的方法和设备
公开(公告)号：WO2004084702A9
公开(公告)日：2004-11-25
申请号：PCT/US2004006939
申请日：2004-03-05
申请人： NEOGUIDE SYSTEMS INC , WHITIN KATHERINE , OHLINE ROBERT M , BELSON AMIR , ROTH ALEX , ARNE LAWRENCE W
发明人： WHITIN KATHERINE , OHLINE ROBERT M , BELSON AMIR , ROTH ALEX , ARNE LAWRENCE W
IPC分类号： A61B1/31 , A61B5/06 , A61B5/107 , A61B
CPC分类号： A61B5/068 , A61B1/31 , A61B5/064 , A61B5/1076 , A61B6/12
摘要： Methods and apparatus for tracking insertion depth of endoscopes are described herein. One method for determining endoscopic insertion depth within a body is to utilize a fully instrumented endoscope configured to determine its depth of insertion. Another method uses a datum device which interacts with the endoscope to determine how much of the endoscope has passed by a reference boundary. A fully instrumented endoscope can poll the status of the entire endoscope and then determine its position relative to anatomical boundaries, e.g., the anus. The polled information is obtained by sensors or transponders located along the length of the endoscope. When using an endoscope with a datum, the datum can read positional information by polling the status of sensors or transponders located along the body of the endoscope as the endoscope passes through the anus. The datum can be affixed to the patient or to another fixed reference point.
摘要翻译：本文描述了用于跟踪内窥镜的插入深度的方法和设备。用于确定身体内的内窥镜插入深度的一种方法是利用配置成确定其插入深度的完全仪器化的内窥镜。另一种方法使用与内窥镜相互作用的基准装置来确定内窥镜已经通过参考边界的程度。完全仪器化的内窥镜可以轮询整个内窥镜的状态，然后确定其相对于解剖学边界（例如肛门）的位置。轮询信息由沿内窥镜长度定位的传感器或应答器获得。当使用带有基准的内窥镜时，在内窥镜穿过肛门时，通过轮询内窥镜主体上的传感器或发送应答器的状态，数据可以读取位置信息。基准可以贴在患者身上或固定在另一个固定的基准点上。

78. 发明申请

WO2004084702A2 METHOD AND APPARATUS FOR TRACKING INSERTION DEPTH 审中-公开
标题翻译：跟踪插入深度的方法和装置
公开(公告)号：WO2004084702A2
公开(公告)日：2004-10-07
申请号：PCT/US2004/006939
申请日：2004-03-05
申请人： NEOGUIDE SYSTEMS, INC. , WHITIN, Katherine , OHLINE, Robert, M. , BELSON, Amir , ROTH, Alex , ARNE, Lawrence, W.
发明人： WHITIN, Katherine , OHLINE, Robert, M. , BELSON, Amir , ROTH, Alex , ARNE, Lawrence, W.
IPC分类号： A61B
CPC分类号： A61B5/068 , A61B1/31 , A61B5/064 , A61B5/1076 , A61B6/12
摘要： Methods and apparatus for tracking insertion depth of endoscopes are described herein. One method for determining endoscopic insertion depth within a body is to utilize a fully instrumented endoscope configured to determine its depth of insertion. Another method uses a datum device which interacts with the endoscope to determine how much of the endoscope has passed by a reference boundary. A fully instrumented endoscope can poll the status of the entire endoscope and then determine its position relative to anatomical boundaries, e.g., the anus. The polled information is obtained by sensors or transponders located along the length of the endoscope. When using an endoscope with a datum, the datum can read positional information by polling the status of sensors or transponders located along the body of the endoscope as the endoscope passes through the anus. The datum can be affixed to the patient or to another fixed reference point.
摘要翻译：本文描述了用于跟踪内窥镜插入深度的方法和装置。用于确定体内内窥镜插入深度的一种方法是利用配置成确定其插入深度的完全仪器化的内窥镜。另一种方法使用与内窥镜相互作用的基准装置来确定内窥镜经过参考边界多少。完全检测的内窥镜可以轮询整个内窥镜的状态，然后确定其相对于解剖学边界的位置，例如肛门。被轮询的信息由位于内窥镜长度的传感器或转发器获得。当使用具有基准的内窥镜时，当内窥镜穿过肛门时，基准可以通过轮询位于内窥镜的身体的传感器或应答器的状态来读取位置信息。基准可以固定在病人身上或者固定在另一个固定的参考点上。

79. 发明申请

WO2003092476A2 ENDOSCOPE HAVING A GUIDE TUBE 审中-公开
标题翻译：内窥镜具有导管
公开(公告)号：WO2003092476A2
公开(公告)日：2003-11-13
申请号：PCT/US2003/013600
申请日：2003-05-02
申请人： NEOGUIDE SYSTEMS, INC. , JAFFE, Ross , TARTAGLIA, Joseph, M. , BELSON, Amir
发明人： JAFFE, Ross , TARTAGLIA, Joseph, M. , BELSON, Amir
IPC分类号： A61B
CPC分类号： A61B1/00154 , A61B1/00078 , A61B1/0008 , A61B1/00142 , A61B1/0016 , A61B1/0053 , A61B1/0055 , A61B1/0057 , A61B1/018 , A61B1/31 , A61B5/065 , A61B17/3421 , A61B2017/003 , A61B2017/00336 , A61B2017/3441 , A61B2034/301 , A61M25/0138 , A61M2025/0063 , A61M2025/0681
摘要： An endoscope having a guide tube is described herein. The assembly has an endoscope which is slidably insertable within the lumen of a guide tube. The guide tube is configured to be rigidizable along its entire length from a relaxed configuration. The endoscope has a steerable distal portion to facilitate the steering of the device through tortuous paths. In the relaxed configuration, a portion of the guide tube is able to assume the shape or curve defined by the controllable distal portion of the endoscope. Having assumed the shape or curve of the endoscope, the guide tube may be rigidized by the physician or surgeon to maintain that shape or curve while the endoscope is advanced distally through the tortuous path without having to place any undue pressure against the tissue walls.
摘要翻译：这里描述了具有引导管的内窥镜。组件具有可滑动地插入导管内腔内窥镜。引导管被构造成从松弛构型沿其整个长度可固化。内窥镜具有可操纵的远侧部分，以便于通过曲折路径对装置的转向。在松弛构造中，导管的一部分能够呈现由内窥镜的可控远端限定的形状或曲线。假设内窥镜的形状或曲线，导管可以被医师或外科医生硬化，以在内窥镜通过曲折路径向远侧推进而保持该形状或曲线，而不必对组织壁施加任何不适当的压力。

80. 发明申请

WO2003073920A2 ENDOSCOPE WITH GUIDING APPARATUS 审中-公开
标题翻译：内窥镜与指导装置
公开(公告)号：WO2003073920A2
公开(公告)日：2003-09-12
申请号：PCT/US2003/006078
申请日：2003-02-26
申请人： NEOGUIDE SYSTEMS, INC. , TARTAGLIA, Joseph, M. , BELSON, Amir , OHLINE, Robert, Matthew
发明人： TARTAGLIA, Joseph, M. , BELSON, Amir , OHLINE, Robert, Matthew
IPC分类号： A61B1/00
CPC分类号： A61B1/00078 , A61B1/00154 , A61B1/0053 , A61B1/0055 , A61B1/008 , A61B1/015 , A61B1/31 , A61B5/065 , A61B2034/301 , A61M2025/0063
摘要： An endoscope with guiding apparatus is described herein. A steerable endoscope is described having an elongate body with a manually or selectively steerable distal portion, an automatically controlled portion, a flexible and passively manipulated proximal portion, and an externally controlled and manipulatable tracking rod or guide. The tracking rod or guide is positioned within a guide channel within the endoscope and slides relative to the endoscope. When the guide is in a flexible state, it can conform to a curve or path defined by the steerable distal portion and the automatically controlled portion. The guide can then be selectively rigidized to assume that curve or path. Once set, the endoscope can be advanced over the rigidized guide in a monorail or "piggy-back" fashion so that the flexible proximal portion follows the curve held by the guide until the endoscope reaches a next point of curvature within a body lumen.
摘要翻译：本文描述了具有引导装置的内窥镜。描述了一种可操纵的内窥镜，其具有带有手动或选择性可操纵的远端部分的细长主体，自动控制部分，柔性和被动操纵的近端部分以及外部控制和可操纵的跟踪杆或引导件。跟踪杆或引导件位于内窥镜内的引导通道内并相对于内窥镜滑动。当引导件处于柔性状态时，其可以符合由可转向远端部分和自动控制部分限定的曲线或路径。然后，引导件可以选择性地刚性化以假定该曲线或路径。一旦设定，内窥镜可以以单轨或“背部”的方式前进在刚性引导件上，使得柔性近端部分遵循由引导件保持的曲线，直到内窥镜到达体腔内的下一个曲率点。

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