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61. 发明授权

US06544562B2 Acne treatment including dual-package system 有权
公开(公告)号：US06544562B2
公开(公告)日：2003-04-08
申请号：US09888767
申请日：2001-06-25
申请人： Mohinder Singh , Michael A. Wojcik
发明人： Mohinder Singh , Michael A. Wojcik
IPC分类号： A61K3578
CPC分类号： A61Q19/00 , A61K8/02 , A61K8/368 , A61K8/38 , A61K9/06 , A61K31/192 , A61K31/60 , A61K2800/88 , B05B11/3084 , Y10S435/81 , Y10S514/859 , A61K2300/00
摘要： A dual regimen acne treatment package includes an outer container, and disposed within the outer container first and second inner containers which are separate from each other. Each of the inner containers has an exposed dispensing means, the first inner container containing a solubilized salicylic acid acne treatment composition, and the second inner container containing a solubilized benzoyl peroxide acne treatment composition.

62. 发明授权

US06534098B2 Plant extracts for the treatment of increased bone resorption 有权
标题翻译：植物提取物用于治疗骨吸收增加
公开(公告)号：US06534098B2
公开(公告)日：2003-03-18
申请号：US09803175
申请日：2001-03-09
申请人： Roman Conrad Mühlbauer
发明人： Roman Conrad Mühlbauer
IPC分类号： A61K3578
CPC分类号： A61K36/23 , A23L33/105 , A61K2300/00
摘要： The present invention is concerned with nutritional or pharmaceutical compositions containing an extract or concentrate of a plant from the genus anethum. The compositions of the invention are useful for the treatment or prophylaxis of diseases or conditions which are characterized by increased bone resorption, such as Paget's disease, tumor-induced bone disease or particularly osteoporosis.
摘要翻译：本发明涉及含有来自白血病属植物的提取物或浓缩物的营养或药物组合物。本发明的组合物可用于治疗或预防以吸收增加为特征的疾病或病症，例如佩吉特氏病，肿瘤诱导的骨病或特别是骨质疏松症。

63. 发明授权

US06531166B2 Use of betel leaf extract to induce IFN-gamma production from human peripheral blood T cells and as a Th1 type immunomodulator 失效
公开(公告)号：US06531166B2
公开(公告)日：2003-03-11
申请号：US09746017
申请日：2000-12-26
申请人： Santu Bandyopadhyay , Bikash Pal , Samir Bhattacharya , Mitali Ray , Keshab Chandra Roy
发明人： Santu Bandyopadhyay , Bikash Pal , Samir Bhattacharya , Mitali Ray , Keshab Chandra Roy
IPC分类号： A61K3578
CPC分类号： A61K36/67 , Y10S514/885
摘要： This invention relates to use of betel leaf extract to induce IFN&ggr; from human peripheral blood mononuclear cells and as a Th1 type immuno modulator, wherein the said method comprises the steps of, preparing water extract of betel leaf, preparation of human peripheral blood mononuclear cells, incubation of hPBMC with betel leaf extract for a period of 18-48 hours, extraction of RNA for cytokine specific RT-PCR or for flow cytometry for the detection of intracellular cytokine protein, subjecting RNA for RT-PCR to obtain PCR products using IFN&ggr; specific known primers, and enhancement of IFN&ggr; as reflected by IFN&ggr; specific band.

64. 发明授权

US06495172B1 Method of using steam ironing of fabrics as a way of causing reduction of physiological and/or subjective reactivity to stress in humans 有权
标题翻译：使用蒸汽熨烫织物的方法作为降低人类生理和/或主观反应性的方法
公开(公告)号：US06495172B1
公开(公告)日：2002-12-17
申请号：US09868342
申请日：2001-06-15
申请人： Paul Amaat France , Arseni V. Radomyselski
发明人： Paul Amaat France , Arseni V. Radomyselski
IPC分类号： A61K3578
CPC分类号： A61K9/007 , A61K36/00 , A61K2300/00
摘要： A method of using steam ironing of fabrics as a way of causing reduction of physiological and/or subjective reactivity to stress in a human is provided. The method includes the steps of providing a stress reducing composition comprising one or more of a volatile natural essential oil and water. The composition is adapted to not cause staining of fabrics. The method includes delivering the stress reducing composition into a liquid container of a steam iron and heating the steam iron. The method further includes releasing vapors of the stress reducing composition produced within the liquid container of the steam iron upon heating into ambient air. The method still further includes the step of causing reduction of physiological and/or subjective reactivity to stress in the human by one of more of transdermal ingestion or inhalation of the vapors by the human.
摘要翻译：提供了一种使用蒸汽熨烫织物作为在人体中降低生理和/或主观反应性的方法。该方法包括提供包含挥发性天然精油和水中的一种或多种的减压组合物的步骤。该组合物适于不引起织物染色。该方法包括将减压组合物输送到蒸汽熨斗的液体容器中并加热蒸汽熨斗。该方法还包括在加热到环境空气中时释放在蒸汽熨斗的液体容器内产生的减压组合物的蒸汽。该方法还包括通过人的多种透皮摄取或吸入蒸气而引起人体的生理和/或主观反应性降低的步骤。

65. 发明授权

US06495170B1 Method of increasing the presence of glutathione in cells 有权
标题翻译：增加细胞中谷胱甘肽的存在的方法
公开(公告)号：US06495170B1
公开(公告)日：2002-12-17
申请号：US09639469
申请日：2000-08-16
申请人： Hobbe Friso Smit , Klaske van Norren , Robert Johan Joseph Hageman
发明人： Hobbe Friso Smit , Klaske van Norren , Robert Johan Joseph Hageman
IPC分类号： A61K3578
CPC分类号： A61K31/198 , A23L33/105 , A23L33/15 , A23L33/155 , A23L33/16 , A23L33/175 , A61K31/355 , A61K31/375 , A61K36/28 , A61K36/79 , A61K36/80 , A61K36/82 , A61K36/9066 , Y10S514/893 , A61K2300/00
摘要： A method for increasing the presence of glutathione in cells including treating or preventing impaired liver function by administering a composition which includes a precursor of gluthathione, and enhancer of glutathione biosynthesis, and a third component which is a lignan or the third component is a combination of an enhancer of gluthathione regeneration and an enhancer of glutathione-mediated conjugation. The precursor of gluthathione is cysteine or is a functional equivalent of cysteine which yields cysteine when administered to a mammal undergoing treatment.
摘要翻译：一种增加细胞中谷胱甘肽存在的方法，包括通过施用包含谷胱甘肽生物合成前体的组合物和作为木质素或第三组分的第三组分的组合物来治疗或预防肝功能受损，所述组合物是木素素或第三组分的组合谷胱甘肽再生的增强剂和谷胱甘肽介导的缀合的增强子。谷胱甘肽的前体是半胱氨酸，或当被施用于正在进行治疗的哺乳动物时产生半胱氨酸的半胱氨酸的功能等同物。

66. 发明授权

US06488968B2 Preparation of fiber, L-glutamine and a soy derivative for the purpose of enhancement of isoflavone bioavailability 失效
标题翻译：为提高异黄酮的生物利用度，制备纤维，L-谷氨酰胺和大豆衍生物
公开(公告)号：US06488968B2
公开(公告)日：2002-12-03
申请号：US10080809
申请日：2002-02-22
申请人： Stephen M. Paul , Charles C. Hsu , Qing-Fu Hu , Daniel Shu , Melissa See
发明人： Stephen M. Paul , Charles C. Hsu , Qing-Fu Hu , Daniel Shu , Melissa See
IPC分类号： A61K3578
CPC分类号： A61K9/205 , A23L33/105 , A23V2002/00 , A61K45/06 , A23V2250/062 , A23V2250/506 , A23V2250/28 , A23V2250/2116 , A23V2250/5072
摘要： A method of enhancing phytoestrogen bioavailability and a method for supplementing the dietary needs of warm blooded animals comprising orally administering an effective amount of a dietary supplement composition comprising a phytoestrogen, a fiber and L-glutamine, and optionally N-acetyl-D-glucosamine, in admixture with a biologically acceptable inert carrier.
摘要翻译：一种增强植物雌激素生物利用度的方法和补充温血动物膳食需求的方法，其包括口服施用有效量的包含植物雌激素，纤维和L-谷氨酰胺以及任选的N-乙酰基-D-葡糖胺的膳食补充剂组合物，与生物学上可接受的惰性载体混合。

67. 发明授权

US06488967B1 Gastric acid secretion 失效
标题翻译：胃酸分泌
公开(公告)号：US06488967B1
公开(公告)日：2002-12-03
申请号：US09691582
申请日：2000-10-18
申请人： John Hakkinen , Roelof Marthinus Horak , Vinesh Maharaj
发明人： John Hakkinen , Roelof Marthinus Horak , Vinesh Maharaj
IPC分类号： A61K3578
CPC分类号： A61K31/704 , A61K31/57 , A61K31/575 , A61K36/27 , Y10S514/925
摘要： A method of treating a disorder of the alimentary system in an animal by administration to the animal an effective amount of an extract of a plant of the genus Hoodia or Trichocaulon; or a compound of the formula is described.
摘要翻译：一种通过向动物施用有效量的Hoodia或Trichocaulon属的植物提取物来治疗动物中的消化系统疾病的方法; 或所述的式的化合物。

68. 发明授权

US06486169B1 Botanical drug for treatment and prevention of alzhimer's disease 有权
标题翻译：用于治疗和预防alzhimer病的植物药
公开(公告)号：US06486169B1
公开(公告)日：2002-11-26
申请号：US10078335
申请日：2002-02-19
申请人： Yaguang Liu
发明人： Yaguang Liu
IPC分类号： A61K3578
CPC分类号： A61K31/44 , A61K36/11 , A61K2300/00
摘要： The present invention related to safe botanical drug for treatment and prevention of Alzheimer's disease. Specifically, this invention proves a safe botanical drug, Huperzine (HUE) and Clausenamide (CLE) and their preparation. HUE has the following pharmaceutical functions: inhibiting acetylcholinesterase (CAT), increasing memory, decreasing Alzheimer amyloid protein, increasing RNA and protein synthesis of brain, increasing calcium in brain, decreasing superoxide anion. CLE has the following pharmaceutical functions: increasing memory, decreasing Alzheimer amyloid protein, increasing RNA and protein synthesis of brain, increasing calcium in brain, decreasing superoxide anion, increasing long-term potentiation and increasing dopanmine (DA). It is important that HUE combined with CLE have stronger function as mentioned above.
摘要翻译：本发明涉及用于治疗和预防阿尔茨海默病的安全植物药物。具体来说，本发明证明了一种安全的植物药物石杉碱（HUE）和克劳森酰胺（CLE）及其制备方法.HUE具有以下制药功能：抑制乙酰胆碱酯酶（CAT），增加记忆力，减少阿尔茨海默淀粉样蛋白，增加RNA和蛋白质合成脑，增加脑中的钙，减少超氧化物阴离子.LE具有以下药物功能：增加记忆力，减少阿尔茨海默氏淀粉样蛋白，增加脑中的RNA和蛋白质合成，增加脑中的钙，减少超氧阴离子，增加长期增强和增加多巴胺（DA）。重要的是，HUE结合CLE具有如上所述的更强的功能。

69. 发明授权

US06482447B2 Method and composition for the treatment of benign prostate hypertrophy (BPH) and prevention of prostate cancer 失效
公开(公告)号：US06482447B2
公开(公告)日：2002-11-19
申请号：US09884622
申请日：2001-06-18
申请人： Chase Revel
发明人： Chase Revel
IPC分类号： A61K3578
CPC分类号： A61K36/185 , A61K36/736 , A61K36/889 , A61K2300/00
摘要： Compositions comprising lycopene, Serenoa repens, Pygeum africanum, and Urtica dioica are provided. The compositions are preferably formulated with an alcohol extract of the dried, cut plant parts. Methods of using such compositions for treating various conditions and diseases, including benign prostatic hypertrophy and prostate cancer are also provided.

70. 发明授权

US06475537B1 Hops acid antibacterial compositions 失效
标题翻译：蜂巢酸抗菌组合物
公开(公告)号：US06475537B1
公开(公告)日：2002-11-05
申请号：US09626851
申请日：2000-07-27
申请人： William King , Xintian Ming
发明人： William King , Xintian Ming
IPC分类号： A61K3578
CPC分类号： A61Q17/005 , A23L3/3472 , A23L3/3508 , A61K8/44 , A61K8/97 , A61K2800/51 , A61Q5/00 , A61Q5/02 , A61Q11/00 , A61Q19/00 , A61Q19/10 , C11D3/382
摘要： An antibacterial composition of matter comprising: (a) one or more hops acid or hops acid derivatives or hops resin or hops resin derivatives; and (b) one or more food grade surfactants, surface active agents, chelating agents, antioxidants, and/or organic acids is provided.
摘要翻译：一种物质的抗菌组合物，包括：（a）一种或多种啤酒花酸或啤酒花酸衍生物或啤酒花树脂或啤酒花树脂衍生物; 和（b）提供一种或多种食品级表面活性剂，表面活性剂，螯合剂，抗氧化剂和/或有机酸。

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