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61. 发明授权

US07727243B2 Systems, methods and devices for removing obstructions from a blood vessel 失效
公开(公告)号：US07727243B2
公开(公告)日：2010-06-01
申请号：US11046563
申请日：2005-01-28
申请人： Ivan Sepetka , Emily Vu , Dan Nguyen , John Miller , Ryan Pierce , Tiffany Tran Ngo , Norman Fung
发明人： Ivan Sepetka , Emily Vu , Dan Nguyen , John Miller , Ryan Pierce , Tiffany Tran Ngo , Norman Fung
IPC分类号： A61B17/22
CPC分类号： A61B17/22031 , A61B17/221 , A61B17/320725 , A61B18/1492 , A61B2017/22034 , A61B2017/2217 , A61B2017/320716 , A61B2018/00214 , A61B2018/00898
摘要： Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction.

62. 发明申请

US20090318941A1 Self-Expandable Endovascular Device For Aneurysm Occlusion 审中-公开
标题翻译：用于动脉瘤闭塞的自扩张血管内装置
公开(公告)号：US20090318941A1
公开(公告)日：2009-12-24
申请号：US12294210
申请日：2007-03-23
申请人： Ivan Sepetka , Maria G. Aboytes , Hong Thu Doan , Ricardo Aboytes , Steven Hochberg , Peter Costantino , Craig F. Friedman , Arindam Datta
发明人： Ivan Sepetka , Maria G. Aboytes , Hong Thu Doan , Ricardo Aboytes , Steven Hochberg , Peter Costantino , Craig F. Friedman , Arindam Datta
IPC分类号： A61B17/08 , A61M25/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12172 , A61B17/12181 , A61B90/39 , A61B2017/00526 , A61B2017/00867 , A61B2017/00893 , A61B2017/12095
摘要： The self-expandable endovascular apparatus for aneurysm occlusion of the invention comprises a deformable shape memory frame with at least a partial segment covering comprised of a matrix implant material. The device can be folded and/or stretched to adopt a narrow profile for loading into a coaxial delivery device and expands in place as it adopts its original shape on release from the device into an aneurysm. A method of treating an aneurysm, comprises the steps of: (a) providing the self-expandable endovascular apparatus inserted into a lumen of a delivery device comprising a proximal end and a distal end, the distal end having a distal tip; (b) advancing the distal tip of the delivery device into an opening in an aneurysm having an interior sac; (c) advancing the apparatus through the lumen into the opening; and (d) withdrawing the delivery device, whereby the apparatus expands into the sac and covers the opening.
摘要翻译：本发明的用于动脉瘤闭塞的自扩张型血管内装置包括具有由基质植入材料构成的至少部分段覆盖物的可变形形状记忆框架。该装置可以被折叠和/或拉伸以采用窄的轮廓以装载到同轴输送装置中，并且在从装置释放到动脉瘤中时采用其原始形状而扩展就位。一种治疗动脉瘤的方法，包括以下步骤：（a）提供插入到包括近端和远端的输送装置的内腔中的自扩张型血管内装置，所述远端具有远端; （b）将输送装置的远端前进到具有内囊的动脉瘤的开口中; （c）使设备通过内腔进入开口; 和（d）取出输送装置，从而使装置膨胀成囊并覆盖开口。

63. 再颁专利

USRE41029E1 Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas 有权
标题翻译：动脉，静脉，动脉瘤，血管畸形和动静脉瘘中血栓形成的血管内电解可分离线和尖端
公开(公告)号：USRE41029E1
公开(公告)日：2009-12-01
申请号：US11377895
申请日：2006-03-15
申请人： Guido Guglielmi , Ivan Sepetka
发明人： Guido Guglielmi , Ivan Sepetka
IPC分类号： A61B18/04 , A61B17/12 , A61B18/14 , A61B18/12 , A61B17/00
CPC分类号： A61M25/09 , A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/1215 , A61B17/12172 , A61B18/1402 , A61B18/1492 , A61B90/39 , A61B2017/00292 , A61B2017/12054 , A61B2017/12063 , A61B2017/12095 , A61B2017/22038 , A61B2018/00678 , A61B2018/00761 , A61B2018/00875 , A61B2018/00886 , A61B2018/1226 , A61B2018/1253 , A61B2018/126 , A61B2018/1266 , A61B2018/1435 , A61B2018/1495 , A61B2090/3966 , A61M2025/09175
摘要： An artery, vein, aneurysms vascular malformation or arterial fistula is occluded through endovascular occlusion by the endovascular insertion of a platinum wire and/or tip into the vascular cavity. The vascular cavity is packed with the tip to obstruct blood flow or access of blood in the cavity such that the blood clots in the cavity and an occlusion if formed. The tip may be elongate and flexible so that it packs the cavity by being folded upon itself a multiple number of times, or may pack the cavity by virtue of a filamentary or fuzzy structure of the tip. The tip is then separated from the wire mechanically or by electrolytic separation of the tip from the wire. The wire and the microcatheter are thereafter removed leaving the tip embedded in the thrombus formed within the vascular cavity. Movement of wire in the microcatheter is more easily tracked by providing a radioopaque proximal marker on the microcatheter and a corresponding indicator marker on the wire. Electrothrombosis is facilitate by placing the ground electrode on the distal end of the microcatheter and flowing current between the microcatheter electrode and the tip.REEAXMINATION RESULTS The questions raised in reexamination request 90/007,231, filed Oct. 4, 2004 have been considered and the results thereof are reflected in this reissue patent which constitutes the reexamination certificate required by 35 U.S.C. 307 as provided in 37 CFR 1.570(e), for ex parte reexaminations, or the reexamination certificate required by 35 U.S.C. 316 as provided in 37 CFR 1.99(e) for inter partes reexaminations.
摘要翻译：动脉，静脉，动脉瘤血管畸形或动脉瘘通过血管内插入铂丝和/或尖端进入血管腔而通过血管内闭塞而闭塞。血管腔填充有尖端以阻止血液流动或进入腔中的血液，使得腔中的血块凝块和形成闭塞。尖端可以是细长的和柔性的，使得其通过在其自身上折叠多次来包装空腔，或者可以通过尖端的丝状或模糊结构来包装空腔。然后将尖端机械地从线分离，或者通过电极将电极与线分离。之后取出线和微导管，留下尖端嵌入形成在血管腔内的血栓。通过在微导管上提供不透射线的近端标记物和线上的相应指示标记，更容易跟踪导线在微导管中的移动。通过将接地电极放置在微导管的远端并在微导管电极和尖端之间流动电流来促进血栓形成。审议结果2004年10月4日提交的复审请求90 / 007,231中提出的问题已被考虑，其结果反映在该重新颁发专利中，该专利构成了35U.S.C.所要求的复审证书。根据第37 CFR 1.570（e）条规定，单方面复审或35 U.S.C.所要求的复审证书。 316，如第37 CFR 1.99（e）条所述，用于跨部门复审。

64. 发明授权

US07534252B2 Systems, methods and devices for removing obstructions from a blood vessel 有权
公开(公告)号：US07534252B2
公开(公告)日：2009-05-19
申请号：US11038906
申请日：2005-01-18
申请人： Ivan Sepetka , Martin Dieck , Son Gia , John Miller , Ryan Pierce , Maria Aboytes , Tiffany Tran Ngo , Dan Nguyen , Emily Vu
发明人： Ivan Sepetka , Martin Dieck , Son Gia , John Miller , Ryan Pierce , Maria Aboytes , Tiffany Tran Ngo , Dan Nguyen , Emily Vu
IPC分类号： A61M29/00
CPC分类号： A61B17/221 , A61B17/22031 , A61B18/1492 , A61B2017/22034 , A61B2017/22035 , A61B2017/2212 , A61B2017/2215 , A61B2017/2217 , A61B2018/00214 , A61B2018/00898 , A61B2090/034 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0067 , A61F2230/0091 , A61M25/0068 , A61M25/0074 , A61M25/008 , A61M25/0082 , A61M25/10 , A61M2025/0096
摘要： Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction.

65. 发明申请

US20080109032A1 Systems, methods and devices for removing obstructions from a blood vessel 有权
公开(公告)号：US20080109032A1
公开(公告)日：2008-05-08
申请号：US12005989
申请日：2007-12-28
申请人： Ivan Sepetka , Emily Vu , Dan Nguyen , John Miller , Ryan Pierce , Tiffany Ngo , Norman Fung
发明人： Ivan Sepetka , Emily Vu , Dan Nguyen , John Miller , Ryan Pierce , Tiffany Ngo , Norman Fung
IPC分类号： A61M29/00
CPC分类号： A61B17/22031 , A61B17/221 , A61B17/320725 , A61B18/1492 , A61B2017/00287 , A61B2017/22034 , A61B2017/22035 , A61B2017/22067 , A61B2017/2212 , A61B2017/2217 , A61B2017/320716 , A61B2018/00214 , A61B2018/00898
摘要： Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction.

66. 发明申请

US20060265044A1 Methods and devices for protecting passageway in a body when advancing devices through the passageway 审中-公开
标题翻译：用于在通过通道推进装置时保护身体中的通道的方法和装置
公开(公告)号：US20060265044A1
公开(公告)日：2006-11-23
申请号：US11398747
申请日：2006-04-03
申请人： Hanson Gifford , Ivan Sepetka , Mark Deem , Douglas Sutton , Allan Will , Martin Dieck , Sunmi Chew
发明人： Hanson Gifford , Ivan Sepetka , Mark Deem , Douglas Sutton , Allan Will , Martin Dieck , Sunmi Chew
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/0095 , A61F2/013 , A61F2/90 , A61F2/954 , A61F2/958 , A61F2/97 , A61F2002/018 , A61F2002/061 , A61F2002/065 , A61F2002/072 , A61F2002/075 , A61F2002/9511 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2250/0098
摘要： A liner is advanced through a narrowed region in a vessel such as the internal carotid artery. The liner is advanced through the narrowed region in a collapsed position. A stent is then advanced through the liner and expanded to open the narrowed region. The liner may also have an anchor which expands an end of the liner before the stent is introduced.
摘要翻译：衬垫穿过诸如颈内动脉的血管中的狭窄区域前进。衬里在折叠位置前进通过狭窄区域。然后将支架推进穿过衬垫并膨胀以打开变窄的区域。衬垫还可以具有在引入支架之前膨胀衬套的端部的锚固件。

67. 发明申请

US20060195137A1 Systems, methods and devices for removing obstructions from a blood vessel 有权
公开(公告)号：US20060195137A1
公开(公告)日：2006-08-31
申请号：US11250190
申请日：2005-10-13
申请人： Ivan Sepetka , Martin Dieck , Son Gia , John Miller , Ryan Pierce , Maria Aboytes , Tiffany Ngo
发明人： Ivan Sepetka , Martin Dieck , Son Gia , John Miller , Ryan Pierce , Maria Aboytes , Tiffany Ngo
IPC分类号： A61M29/00
CPC分类号： A61B17/221 , A61B17/22 , A61B17/22031 , A61B2017/00336 , A61B2017/22034 , A61B2017/22094 , A61B2017/2212 , A61B2017/2215 , A61B2017/2217 , A61F2/013 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2230/0067 , A61F2230/0091 , A61F2250/0065
摘要： Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction.

68. 发明申请

US20050222580A1 Methods and devices for delivering occlusion elements 审中-公开
公开(公告)号：US20050222580A1
公开(公告)日：2005-10-06
申请号：US11061127
申请日：2005-02-18
申请人： Hanson Gifford , Ivan Sepetka , Son Gia , Maria Aboytes , Ryan Pierce , Tina Patel , Christopher Ken
发明人： Hanson Gifford , Ivan Sepetka , Son Gia , Maria Aboytes , Ryan Pierce , Tina Patel , Christopher Ken
IPC分类号： A61B17/00 , A61B17/12 , A61M25/00 , A61M29/00
CPC分类号： A61B17/1214 , A61B17/12022 , A61B17/12145 , A61B17/1215 , A61B2017/00477 , A61B2017/12059 , A61M25/007
摘要： A device for delivering an occlusion element, or other medical device, which includes a fluid dissolvable bond. The occlusion element is coupled to the delivery element with the fluid dissolvable bond. The bond may be dissolved by delivering a fluid through the delivery element either through the delivery element itself or through a tube positioned in the delivery element.

69. 发明申请

US20050125024A1 Systems, methods and devices for removing obstructions from a blood vessel 有权
公开(公告)号：US20050125024A1
公开(公告)日：2005-06-09
申请号：US11038906
申请日：2005-01-18
申请人： Ivan Sepetka , Martin Dieck , Son Gia , John Miller , Ryan Pierce , Maria Aboytes , Tiffany Ngo , Dan Nguyen , Emily Vu
发明人： Ivan Sepetka , Martin Dieck , Son Gia , John Miller , Ryan Pierce , Maria Aboytes , Tiffany Ngo , Dan Nguyen , Emily Vu
IPC分类号： A61B17/22 , A61F2/01 , A61F2/958 , A61M20060101 , A61M25/00 , A61M29/00
CPC分类号： A61B17/221 , A61B17/22031 , A61B18/1492 , A61B2017/22034 , A61B2017/22035 , A61B2017/2212 , A61B2017/2215 , A61B2017/2217 , A61B2018/00214 , A61B2018/00898 , A61B2090/034 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0067 , A61F2230/0091 , A61M25/0068 , A61M25/0074 , A61M25/008 , A61M25/0082 , A61M25/10 , A61M2025/0096
摘要： Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction.

70. 发明授权

US06746468B1 Devices and methods for treating vascular malformations 有权
公开(公告)号：US06746468B1
公开(公告)日：2004-06-08
申请号：US09695637
申请日：2000-10-24
申请人： Ivan Sepetka , Martin S. Dieck , Son Gia
发明人： Ivan Sepetka , Martin S. Dieck , Son Gia
IPC分类号： A61M2900
CPC分类号： A61B18/1492 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12118 , A61B17/12136 , A61B17/1214 , A61B17/12145 , A61B17/12168 , A61B17/12172 , A61B17/12177 , A61B17/12186 , A61B2017/00867 , A61B2017/1205 , A61B2017/12068 , A61B2017/12081 , A61B2017/12095 , A61B2018/00214 , A61B2018/00416 , A61B2018/1495 , A61M25/0068 , A61M25/007 , A61M25/0074 , A61M25/0082 , A61M25/1002 , A61M29/00 , A61M29/02 , A61M2025/1084 , A61M2205/36
摘要： The invention is also directed to a device for treating an aneurysm which has a cover covering the neck of the aneurysm and a lateral portion extending into the aneurysm. The invention is also directed to a cover which is used to cover the neck of the aneurysm thereby isolating the aneurysm from the parental vessel.

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