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    • 65. 发明授权
    • Novel organosilicon compounds and anti-transplanted tumor agents
containing the same
    • 新型有机硅化合物和含有其的抗移植肿瘤剂
    • US4278666A
    • 1981-07-14
    • US124957
    • 1980-02-26
    • Shigeshi ToyoshimaRyuichi SatoKoichi ItoToshio ShinoharaYasushi Yamamoto
    • Shigeshi ToyoshimaRyuichi SatoKoichi ItoToshio ShinoharaYasushi Yamamoto
    • A61K31/695A61P35/00C07F7/08C07F7/10A61K31/725A01N55/00
    • C07F7/0818
    • The invention provides a novel class of organosilicon compounds and a method for the preparation thereof as well as an anti-tumor agent containing the compound having very remarkable anti-tumor activity but with very low toxicity. The inventive compound is a (trihydrocarbylsilylmethyloxyimino)alkane, which is a silicon-containing oxime compound hitherto not described in any prior art literatures, represented by the general formula R.sup.1.sub.3 Si--CH.sub.2 --O--N.dbd.Y, R.sup.1 is a substituted or unsubstituted monovalent hydrocarbon group having from 1 to 10 carbon atoms and Y is a divalent hydrocarbon group denoted by .dbd.CR.sup.2 R.sup.3 or .dbd.CR.sup.4, R.sup.2 and R.sup.3, which may be identical or different, having the same meaning as R.sup.1 defined above and R.sup.4 being an alkylene group to form a ring structure jointly with the carbon atom directly bonded to the nitrogen atom. Typical examples of the compounds are: 2-(trimethylsilylmethyloxyimino) butane, 2-(trimethylsilylmethyloxyimino)propane, 2-(dimethylphenylsilylmethyloxyimino) butane and trimethylsilylmethyloxyiminocyclohexane.
    • 本发明提供了一类新颖的有机硅化合物及其制备方法以及含有非常显着的抗肿瘤活性但毒性非常低的化合物的抗肿瘤剂。 本发明化合物是一种(三烃基甲硅烷基甲氧基亚氨基)烷烃,其是迄今尚未在任何现有技术文献中描述的含硅肟化合物,由通式R 13 Si-CH 2 -ON A = Y表示,R 1是取代或未取代的单价烃基, 1至10个碳原子,Y是由= CR 2 R 3或= CR 4,R 2和R 3表示的二价烃基,其可以相同或不同,具有与上述R 1相同的含义,R 4为形成环的亚烷基 与与氮原子直接键合的碳原子结合。 化合物的典型实例是:2-(三甲基甲硅烷基甲氧基亚氨基)丁烷,2-(三甲基甲硅烷基甲氧基亚氨基)丙烷,2-(二甲基苯基甲硅烷基甲氧基亚氨基)丁烷和三甲基甲硅烷基甲氧基亚氨基环己烷。
    • 66. 发明授权
    • Apparatus for an automatic musical performance
    • 用于自动演奏的装置
    • US4126071A
    • 1978-11-21
    • US773542
    • 1977-03-02
    • Kazuo KamataYasushi Yamamoto
    • Kazuo KamataYasushi Yamamoto
    • G10H1/38G10H1/00
    • G10H1/38Y10S84/12
    • An arrangement for providing an automatic musical performance in which a digital signal indicating a root tone is obtained by depression of a key, and is added in sequential order with digital signals obtained from a memory circuit. The latter is driven by output pulses of a rhythm pulse generator. Binary coded signals from the outputs of the adder, open and close plural gate circuits interposed in plural tone source signal passing circuits. One decoder is provided at the plural output terminals of the adder, and plural output terminals of that decoder are connected to control terminals of respective gate circuits. The decoder converts the binary code signals into address signals. An additional decoder may be provided at the output of the adder for converting the output binary code signals to binary-coded duodecimal codes.
    • 一种用于提供自动演奏的装置,其中通过按下键获得指示根音的数字信号,并且以从存储器电路获得的数字信号按顺序相加。 后者由节律脉冲发生器的输出脉冲驱动。 来自加法器的输出的二进制编码信号,打开和关闭插入多个音源信号通过电路中的多个门电路。 在加法器的多个输出端提供一个解码器,该解码器的多个输出端连接到各个门电路的控制端。 解码器将二进制码信号转换为地址信号。 可以在加法器的输出处提供附加的解码器,用于将输出的二进制码信号转换为二进制编码的十进制代码。
    • 67. 发明授权
    • Actuator control method and actuator control device
    • 执行器控制方式和执行器控制装置
    • US09558897B2
    • 2017-01-31
    • US14232167
    • 2012-06-21
    • Yasushi Yamamoto
    • Yasushi Yamamoto
    • H01H9/00G05B19/416
    • H01H9/00G05B19/416G05B2219/39357G05B2219/41086G05B2219/41087G05B2219/43041G05B2219/43045G05B2219/43099G05B2219/43112G05B2219/43114Y10T307/951
    • An actuator control method and an actuator control device that incorporate an element of feedback control in time optimal control, including: a calculation step of calculating a switching time at which an acceleration output is switched to a deceleration output and an end time of the deceleration output expressed by time elapsed from a calculation time at which calculation for control is performed using a maximum acceleration and a maximum deceleration, which are measured in advance, at the time of the maximum output of control force of an actuator; a control output step of setting the control force of the actuator to a maximum acceleration output from the calculation time to the switching time, setting the control force of the actuator to a maximum deceleration output from the switching time to the end time, and ending the output of the control force at the end time, and an update step of calculating and updating the switching time and the end time by repeating the calculation step at each preset time.
    • 一种致动器控制方法和致动器控制装置,其包括时间最优控制中的反馈控制元件,包括:计算加速度输出切换到减速输出的切换时间和减速输出的结束时间的计算步骤 由在执行器的控制力的最大输出时使用预先测量的最大加速度和最大减速度进行控制计算的计算时间经过的时间表示; 控制输出步骤,其将所述致动器的控制力设定为从所述计算时间到所述切换时间的最大加速度输出,将所述致动器的控制力设定为从所述切换时间到结束时间的最大减速度输出, 输出结束时的控制力,以及更新步骤,通过在每个预设时间重复计算步骤来计算和更新切换时间和结束时间。