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51. 发明申请

US20060212047A1 Systems and Methods for Treating Septal Defects 审中-公开
公开(公告)号：US20060212047A1
公开(公告)日：2006-09-21
申请号：US11422865
申请日：2006-06-07
申请人： Ryan Abbott , W. Belef , Dean Carson , Rajiv Doshi , Richard Ginn , Ronald Jabba , William Gray
发明人： Ryan Abbott , W. Belef , Dean Carson , Rajiv Doshi , Richard Ginn , Ronald Jabba , William Gray
IPC分类号： A61B17/10
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/221 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/0649 , A61B2017/22047 , A61B2017/2926 , A61B2017/306
摘要： A system for treating a septal defect having an implantable treatment apparatus and devices for delivering the implantable treatment apparatus and methods for treating a septal defect are provided. The implantable treatment apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the implantable apparatus, a stabilization device configured to stabilize the body member and a positioning device configured to position the delivery device in a desired location.

52. 发明申请

US20060190038A1 Closure device and methods for making and using them 有权
公开(公告)号：US20060190038A1
公开(公告)日：2006-08-24
申请号：US11344891
申请日：2006-02-01
申请人： Michael Carley , Richard Ginn , Javier Sagasegui , Ronald Jabba , William Aldrich , W. Belef
发明人： Michael Carley , Richard Ginn , Javier Sagasegui , Ronald Jabba , William Aldrich , W. Belef
IPC分类号： A61B17/08
CPC分类号： A61B17/08 , A61B17/0057 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/083 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00668 , A61B2017/00672 , A61B2017/00867 , A61B2017/0641 , A61B2017/081 , H03K3/356139 , H03K3/356156
摘要： A clip for engaging tissue includes a generally annular-shaped body defining a plane and disposed about a central axis extending normal to the plane. The body includes alternating inner and outer curved regions, defining a zigzag pattern about a periphery of the clip. The body is biased towards a planar configuration lying in the plane and deflectable towards a transverse configuration extending out of the plane. Tines extend from the inner curved regions, the tines being oriented towards the central axis in the planar configuration, and parallel to the central axis in the transverse configuration. The tines may include primary tines and secondary tines that are shorter than the primary tines. The primary tines may be disposed on opposing inner curved regions and oriented towards one another such that they overlap in the planar configuration.

53. 发明申请

US20060167484A1 Closure device and methods for making and using them 有权
公开(公告)号：US20060167484A1
公开(公告)日：2006-07-27
申请号：US11390586
申请日：2006-03-27
申请人： Michael Carley , Richard Ginn , Javier Sagastegui , Ronald Jabba , William Aldrich , W. Belef
发明人： Michael Carley , Richard Ginn , Javier Sagastegui , Ronald Jabba , William Aldrich , W. Belef
IPC分类号： A61B17/08
CPC分类号： A61B17/08 , A61B17/0057 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/083 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00668 , A61B2017/00672 , A61B2017/00867 , A61B2017/0641 , A61B2017/081 , H03K3/356139 , H03K3/356156
摘要： A clip for engaging tissue includes a generally annular-shaped body defining a plane and disposed about a central axis extending normal to the plane. The body includes alternating inner and outer curved regions, defining a zigzag pattern about a periphery of the clip. The body is biased towards a planar configuration lying in the plane and deflectable towards a transverse configuration extending out of the plane. Tines extend from the inner curved regions, the tines being oriented towards the central axis in the planar configuration, and parallel to the central axis in the transverse configuration. The tines may include primary tines and secondary tines that are shorter than the primary tines. The primary tines may be disposed on opposing inner curved regions and oriented towards one another such that they overlap in the planar configuration.

54. 发明申请

US20060135989A1 Closure device 有权
标题翻译：封闭装置
公开(公告)号：US20060135989A1
公开(公告)日：2006-06-22
申请号：US10787073
申请日：2004-02-24
申请人： Michael Carley , Richard Ginn , Javier Sagastegui , US Sagastegui , Ronald Jabba , William Aldrich , W. Belef
发明人： Michael Carley , Richard Ginn , Javier Sagastegui , US Sagastegui , Ronald Jabba , William Aldrich , W. Belef
IPC分类号： A61B17/08
CPC分类号： A61B17/064 , A61B17/0057 , A61B17/0644 , A61B17/068 , A61B90/39 , A61B2017/00004 , A61B2017/00668 , A61B2017/00867 , A61B2017/0641
摘要： A clip for engaging tissue includes a generally annular-shaped body defining a plane and disposed about a central axis extending normal to the plane. The body includes alternating inner and outer curved regions, defining a zigzag pattern about a periphery of the clip. The body is biased towards a planar configuration lying in the plane and deflectable towards a transverse configuration extending out of the plane. Tines extend from the inner curved regions, the tines being oriented towards the central axis in the planar configuration, and parallel to the central axis in the transverse configuration. The tines include primary tines and secondary tines that are shorter than the primary tines. The primary tines may be disposed on opposing inner curved regions and oriented towards one another. The primary tines are configured such that they are offset from the axes of symmetry of the curved regions from which they extend and are connected to the curved regions by curved or linear regions or are connected directly to the curved regions. The primary tines may overlap the body and may be of different lengths.
摘要翻译：用于接合组织的夹具包括限定平面并围绕垂直于平面延伸的中心轴设置的大致环形的主体。主体包括交替的内部和外部弯曲区域，围绕夹子的周边限定Z字形图案。身体偏向平面构型，该平面构型位于平面内，并可朝向延伸出平面的横向构型偏转。齿从内部弯曲区域延伸，尖齿在平面构型中朝向中心轴线定向，并且在横向构型中平行于中心轴线。尖齿包括比主尖齿短的主要尖齿和次级齿。主尖齿可以设置在相对的内弯曲区域上并且朝向彼此定向。主尖齿被构造成使得它们偏离其延伸的弯曲区域的对称轴线，并且通过弯曲或线性区域连接到弯曲区域，或者直接连接到弯曲区域。主尖齿可能与身体重叠，并且可能具有不同的长度。

55. 发明申请

US20050222614A1 Plug with collet and apparatus and method for delivering such plugs 有权
标题翻译：用夹头和装置和方法插入这种插头
公开(公告)号：US20050222614A1
公开(公告)日：2005-10-06
申请号：US11121715
申请日：2005-05-03
申请人： Richard Ginn , Daniel Wallace , Robert LaDuca
发明人： Richard Ginn , Daniel Wallace , Robert LaDuca
IPC分类号： A61B10/00 , A61B17/00 , A61B17/08
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue includes a plug including external threads, a lumen extending between its proximal and distal ends, and an annular collet slidably disposed within the lumen. The plug is carried on a distal end of a handle device that includes an inner member with a distal end that is slidable axially within the lumen of the body for moving the collet into a reduced cross-sectional region of the lumen, thereby compressing the collet to seal the lumen, and for deploying the plug from the handle device. During use, the plug is delivered into a passage through tissue over a guide wire. Once a desired location is reached, the plug is deployed from the handle device, thereby compressing the collet and sealing the lumen. The guide wire and handle device are removed, leaving the plug to seal the passage.
摘要翻译：用于密封通过组织的通道的装置包括包括外螺纹的塞子，在其近端和远端之间延伸的内腔和可滑动地设置在内腔内的环形夹头。插头被承载在手柄装置的远端上，该手柄装置包括内部构件，该内部构件具有在主体的内腔内可轴向滑动的远端，用于将夹头移动到管腔的减小的横截面区域中，从而压缩夹头以密封管腔，并且用于从手柄装置部署塞子。在使用过程中，塞子通过导丝被输送到穿过组织的通道中。一旦到达期望的位置，插头从手柄装置展开，从而压缩夹头并密封管腔。引导线和手柄装置被移除，留下塞子以密封通道。

56. 发明申请

US20050177189A1 Plug with detachable guidewire element and methods for use 有权
公开(公告)号：US20050177189A1
公开(公告)日：2005-08-11
申请号：US11101058
申请日：2005-04-06
申请人： Richard Ginn , Daniel Wallace , Robert LaDuca
发明人： Richard Ginn , Daniel Wallace , Robert LaDuca
IPC分类号： A61B10/00 , A61B17/00 , A61B17/08
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue includes a bioabsorbable, threaded plug carried by a delivery device. A guide wire is receivable through lumens in the plug and delivery device that includes wings on a bioabsorbable distal portion. With the wings collapsed, the guide wire is advanced through the passage into a blood vessel, the wings expanding once located within the vessel, and the guide wire is withdrawn until the wings contact the vessel wall. The plug is threaded into the passage over the guide wire until the plug is disposed adjacent the wings. The distal portion of the guide wire is secured to the plug, e.g., by compressing a collet within the plug lumen that seals the lumen, and is severed from a proximal portion thereof. Thus, the plug and distal portion are deployed with the plug sealing the passage.

57. 发明申请

US20050119695A1 Closure device and methods for making and using them 审中-公开
标题翻译：关闭装置及其制造和使用的方法
公开(公告)号：US20050119695A1
公开(公告)日：2005-06-02
申请号：US11028133
申请日：2005-01-03
申请人： Michael Carley , Richard Ginn , Javier Sagastegui , Ronald Jabba , William Aldrich , W. Belef
发明人： Michael Carley , Richard Ginn , Javier Sagastegui , Ronald Jabba , William Aldrich , W. Belef
IPC分类号： A61B17/08 , A61B17/00 , A61B17/064 , A61B17/068 , A61B17/10 , A61B19/00 , H03K3/356
CPC分类号： H03K3/356156 , A61B17/0057 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00668 , A61B2017/0641
摘要： A clip for engaging tissue includes a generally annular-shaped body defining a plane and disposed about a central axis extending normal to the plane. The body includes alternating inner and outer curved regions, defining a zigzag pattern about a periphery of the clip. The body is biased towards a planar configuration lying in the plane and deflectable towards a transverse configuration extending out of the plane. Tines extend from the inner curved regions, the tines being oriented towards the central axis in the planar configuration, and parallel to the central axis in the transverse configuration. The tines may include primary tines and secondary tines that are shorter than the primary tines. The primary tines may be disposed on opposing inner curved regions and oriented towards one another such that they overlap in the planar configuration.
摘要翻译：用于接合组织的夹具包括限定平面并围绕垂直于平面延伸的中心轴设置的大致环形的主体。主体包括交替的内部和外部弯曲区域，围绕夹子的周边限定Z字形图案。身体偏向平面构型，该平面构型位于平面内，并可朝向延伸出平面的横向构型偏转。齿从内部弯曲区域延伸，尖齿在平面构型中朝向中心轴线定向，并且在横向构型中平行于中心轴线。尖齿可以包括比主尖齿短的主要尖齿和次要尖齿。主尖齿可以设置在相对的内部弯曲区域上并且朝向彼此定向，使得它们在平面构造中重叠。

58. 发明申请

US20050085856A1 Locator and delivery device and method of use 有权
标题翻译：定位器和配送装置及使用方法
公开(公告)号：US20050085856A1
公开(公告)日：2005-04-21
申请号：US10850795
申请日：2004-05-21
申请人： Richard Ginn
发明人： Richard Ginn
IPC分类号： A61B17/00 , A61B17/22 , A61B19/00 , A61M29/00
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00022 , A61B2017/00637 , A61B2017/0065 , A61B2017/00654 , A61B2017/00672 , A61B2017/22047 , A61B2034/2051 , A61B2090/062 , A61B2090/0811
摘要： This invention relates to apparatus and methods for use in sealing a vascular puncture site and to apparatus and methods for properly locating and deploying a sealing device. The locating apparatus comprises a lumen which extends from an opening in the distal region of the apparatus but located proximally of the sealing device, which lumen extends to another opening in the proximal region of the device. When the distal opening is in communication with blood in a blood vessel, blood flow through the lumen and out of the proximal opening signifies such location to the user. When the sealing device is withdrawn such that the sealing device is deployed such that it blocks the blood flow into the distal port, the user will know the location of the sealing device. In a preferred embodiment, the sealing device is then withdrawn proximally a predetermined distance to assure that no part of the sealing device extends into the blood vessel lumen. The sealing device is then detached from the delivery device.
摘要翻译：本发明涉及用于密封血管穿刺部位的装置和方法以及用于适当定位和展开密封装置的装置和方法。定位装置包括从设备的远侧区域中的开口延伸但位于密封装置的近侧的内腔，该内腔延伸到装置的近侧区域中的另一个开口。当远端开口与血管中的血液连通时，血流通过内腔并离开近端开口表示使用者的这种位置。当密封装置被抽出时，使得密封装置被展开，使得它阻止进入远端口的血流，使用者将知道密封装置的位置。在优选实施例中，然后将密封装置向近侧撤回预定距离，以确保密封装置的任何部分不延伸进入血管内腔。然后将密封装置从输送装置分离。

59. 发明授权

US5875782A Methods and devices for minimally invasive coronary artery revascularization on a beating heart without cardiopulmonary bypass 失效
标题翻译：在没有体外循环的搏动心脏上进行微创冠状动脉血运重建的方法和装置
公开(公告)号：US5875782A
公开(公告)日：1999-03-02
申请号：US752741
申请日：1996-11-14
申请人： Richard M. Ferrari , Charles S. Taylor , Jack W. Lasersohn , Federico J. Benetti , Jodi J. Akin , Richard Ginn , Amr Salahieh
发明人： Richard M. Ferrari , Charles S. Taylor , Jack W. Lasersohn , Federico J. Benetti , Jodi J. Akin , Richard Ginn , Amr Salahieh
IPC分类号： A61B17/00 , A61B17/02 , A61B17/34 , A61B19/00
CPC分类号： A61B17/0206 , A61B2017/00243 , A61B2017/0243 , A61B2017/3484 , A61B2017/3486 , A61B2017/3492
摘要： Methods and devices for revascularization of a patient's coronary artery system which obviate the need to place the patient on cardiopulmonary bypass. A method is provided for revascularizing a patient while the-heart is beating, and includes performing at least one minimally invasive coronary artery bypass graft procedure, or other cardiac surgical procedure, and contemporaneously performing at least one catheter-based procedure in at least one coronary artery. The catheter-based procedure(s) may be either therapeutic or diagnostic or both, and may involve delivering at least one catheter to a coronary artery via a surgical or percutaneous opening in the thoracic cavity or via a percutaneous opening at a location peripheral to the thoracic cavity. The catheter-based procedure or procedures is performed contemporaneously with the bypass graft procedure, and specifically prior to, during, or after anesthetizing the patient for purposes of the bypass graft procedure. An arterial access device is also provided for central cannulation and direct intraoperative catheterization of a patient's coronary artery system on a beating heart. The device includes a tubular member, such as a cannula, having a proximal end and a distal end, and an elongated puncturing member, such as a trocar, which is slideably disposed within the tubular member. The puncturing member has a sharp distal end for puncturing through the wall of a coronary lumen. The arterial access device further includes a sealing member for engaging the coronary lumen wall at the puncture site in order to minimize the leakage of blood from the puncture site.
摘要翻译：用于患者冠状动脉系统血运重建的方法和装置，其不需要将患者置于体外循环。提供了一种在心脏跳动时使患者血运重建的方法，并且包括执行至少一种微创冠状动脉旁路移植手术或其他心脏外科手术，同时在至少一个冠状动脉中执行至少一个基于导管的程序动脉。基于导管的程序可以是治疗性的或诊断的或两者都可以，并且可以涉及通过胸腔中的手术或经皮开口或通过在外周的位置处的经皮开口将至少一个导管递送到冠状动脉胸腔。基于导管的程序或程序与旁路移植手术同时进行，特别是在麻醉患者之前，期间或之后进行旁路移植手术。还提供了一种动脉通路装置，用于中心插管并且在搏动心脏上直接对患者的冠状动脉系统进行导管插入。该装置包括具有近端和远端的管状构件，例如插管，以及可滑动地设置在管状构件内的细长的穿刺构件，例如套管针。穿刺构件具有用于刺穿冠状腔的壁的尖锐远端。动脉进入装置还包括密封构件，用于在穿刺部位处与冠状腔壁接合，以便使来自穿刺部位的血液泄漏最小化。

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