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51. 发明专利

NZ337865A Pressure flow system where a chamber with a fluid inlet port is formed to allow the bone thru, with a pressurizable seal to enable fluid tight engagement and a source fluid pressure with higher than atmospheric pressure 未知
公开(公告)号：NZ337865A
公开(公告)日：2000-12-22
申请号：NZ33786598
申请日：1998-03-11
申请人： OSTEOTECH INC
发明人： SCARBOROUGH NELSON L , MORRIS JOHN W , RUSSELL JAMES L , DOWD MICHAEL
IPC分类号： B08B5/02 , A61L2/00 , A61L27/00 , A61L27/36 , B08B3/02
摘要： A pressure flow system and method for its use are provided for contacting the interior of a fluid permeable, e.g., porous, workpiece. The system includes a fluid pressure chamber having an inlet port and an opening formed in one of the chamber walls. An adjustable seal capable of providing a fluid-tight seal about the exterior of a workpiece having a non-uniform surface is positioned within the opening. Fluid under pressure is supplied to the pressure chamber to force fluid to flow through the internal matrix of the workpiece. In a preferred embodiment, the workpiece is a bone or a section thereof, and the fluid is forced to flow from the endosteal portion of bone to the periosteal portion of bone through the vasculature and porous structure of the bone to remove blood, bone marrow and/or other non-bone constituent(s) from the bone. Alternatively, the fluid can be chosen to decontaminate and/or demineralise the bone, to stain the bone to improve visualization of the bone microvasculature or to impregnate with pharmacological agents (antibiotics, bone growth factors, etc.) so that bone can act as a delivery system.

52. 发明专利

CA2376363A1 RAMP-SHAPED INTERVERTEBRAL IMPLANT 未知
公开(公告)号：CA2376363A1
公开(公告)日：2000-12-14
申请号：CA2376363
申请日：2000-06-08
申请人： OSTEOTECH INC
发明人： SHIMP LAWRENCE A , BOYLE JOHN W , MORRIS JOHN W , DAUGHERTY MARK , BOYCE TODD M , MARTZ ERIK O , KAES DAVID R
IPC分类号： A61F2/00 , A61F2/28 , A61F2/30 , A61F2/44 , A61F2/46
摘要： A ramp-shaped intervertebral implant (10) is disclosed. The implant has a bo dy having a first end (16), a second end (14), a top surface (22) and a bottom surface (24). At least one of the top and bottom surfaces is tapered that converges towards the second end of the body. An opening (26) extends throug h the body, has one end opening onto the top surface of the implant and the other end opening onto the bottom surface of the implant. The implant can be formed from the diaphysis or metaphysis of a long bone, wherein the intramedullary canal of the long bone defines the opening. Alternately, the implant can be made from any biocompatible material having the requisite strength requirement.

53. 发明专利

BR9809051A 未知
公开(公告)号：BR9809051A
公开(公告)日：2000-08-01
申请号：BR9809051
申请日：1998-03-11
申请人： OSTEOTECH INC
发明人： SARBOROUGH NELSON L , MORRIS JOHN W , RUSSELL JAMES L , DOWD MICHAEL
IPC分类号： B08B5/02 , A61L2/00 , A61L27/00 , A61L27/36 , B08B3/02

54. 发明专利

NO20001386L 未知
公开(公告)号：NO20001386L
公开(公告)日：2000-05-18
申请号：NO20001386
申请日：2000-03-16
申请人： OSTEOTECH INC
发明人： SCARBOROUGH NELSON , MORRIS JOHN W
IPC分类号： A61F2/44
摘要： An intervertebral prosthesis includes a bone graft implant member dimensioned for insertion within an intervertebral space defined between adjacent vertebrae and having at least first and second longitudinal sections with respective first and second cross-sectional dimensions. The first cross-sectional dimension of the first implant section is greater than the second cross section dimension of the second implant section to define a stepped region having a retaining surface. Consequently, upon insertion of the implant member within a generally correspondingly dimensioned receiving bed formed within the adjacent vertebrae, the retaining surface facilitates securement therewithin by corresponding engagement with surfaces of the receiving bed. A method for fusion of adjacent vertebrae utilizing the prosthesis is also disclosed.

55. 发明专利

CA2284207A1 PRESSURE FLOW SYSTEM AND METHOD FOR TREATING A FLUID PERMEABLE WORKPIECE SUCH AS BONE 未知
公开(公告)号：CA2284207A1
公开(公告)日：1998-09-24
申请号：CA2284207
申请日：1998-03-11
申请人： OSTEOTECH INC
发明人： SCARBOROUGH NELSON L , MORRIS JOHN W , DOWD MICHAEL , RUSSELL JAMES L
IPC分类号： B08B5/02 , A61L2/00 , A61L27/00 , A61L27/36 , B08B3/02
摘要： A pressure flow system and method for its use are provided for contacting the interior of a fluid permeable, e.g., porous, workpiece. The system includes a fluid pressure chamber having an inlet port and an opening formed in one of the chamber walls. An adjustable seal capable of providing a fluid-tight seal about the exterior of a workpiece having a non-uniform surface is positioned within the opening. Fluid under pressure is supplied to the pressure chamber to force fluid to flow through the internal matrix of the workpiece. In a preferred embodiment, the workpiece is a bone or a section thereof, and the fluid is forced to flow from the endosteal portion of bone to the periosteal portion of bone through the vasculature and porous structure of the bone to remove blood, bone marrow and/or other non-bone constituent(s) from the bone. Alternatively, the fluid can be chosen to decontaminate and/or demineralize the bone, to stain the bone to improve visualization of the bone microvasculature or to impregnate with pharmacological agents (antibiotics, bone growth factors, etc.) so that bone can act as a delivery system.

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