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1. 发明专利

CA2637616A1 INJECTABLE AND MOLDABLE BONE SUBSTITUTE MATERIALS 未知
公开(公告)号：CA2637616A1
公开(公告)日：2007-07-26
申请号：CA2637616
申请日：2007-01-19
申请人： OSTEOTECH INC
发明人： BOYCE TODD M , KAES DAVID R , KNAACK DAVID , RUSSELL JAMES , TUNC DEGER C , BHATTACHARYYA SUBHABRATA , WINTERBOTTOM JOHN
IPC分类号： A61F2/28

2. 发明专利

CA2457686A1 INTERVERTEBRAL IMPANT WITH MOVEMENT RESISTANT STRUCTURE 未知
公开(公告)号：CA2457686A1
公开(公告)日：2003-01-23
申请号：CA2457686
申请日：2002-07-12
申请人： OSTEOTECH INC , KAES DAVID R , MORRIS JOHN W , WINTERBOTTOM JOHN , SHIMP LAWRENCE A , GEISLER FRED
发明人： KAES DAVID R , MORRIS JOHN W , WINTERBOTTOM JOHN , SHIMP LAWRENCE A , GEISLER FRED
IPC分类号： A61B17/86 , A61F2/00 , A61F2/02 , A61F2/28 , A61F2/30 , A61F2/44 , A61L27/36
摘要： An implant unit used in surgery has a body made from osteogenic implantable material and including an implant portion and a retaining portion, which is coupled to and extends transversely to the implant portion. The retaining portion is attached to the sidewall of the adjoining vertebral body or mamma l bone to prevent displacement of the implant portion relative to the vertebra l body or mammal bone and to accelerate fusion therebetween.

3. 发明专利

AU2583102A Spinal intervertebral implant and method of making 未知
公开(公告)号：AU2583102A
公开(公告)日：2002-05-15
申请号：AU2583102
申请日：2001-11-02
申请人： OSTEOTECH INC
发明人： SHIMP LAWERENCE A , ANNUNZIATO STEVEN , MARTZ ERIK , KAES DAVID R
IPC分类号： A61F2/00 , A61F2/02 , A61F2/28 , A61F2/30 , A61F2/44 , A61F2/46
摘要： A C-shaped or ring shaped implant formed of cortical bone has its C-shaped or inner channel filled with a bone promoting material which is preferably demineralized bone fibers formed as a flexible wet sheet or may be cancellous bone, pressed bone fibers formed from demineralized cortical bone chips soaked in acid, or a flex material formed of demineralized bone growth promoting bone fibers. The discrete bone filler element may be secured by a bonding agent, pins or screws, metal, polymer or bone material. The bone filler material is preferably bonded by filling a section of a long bone medullary cavity with wet bone fibers and then drying the fibers to bond them to the outer bone. A filled bone ring may be sliced to form annular filled sections which are then divided into mirror image C-shaped halves each forming an implant. Flex material of compressed bone fibers may be formed with an opening shaped to receive a cortical bone implant element having a C-shaped channel. The flex material surrounds the cortical bone element and fills its channel. Other embodiments are disclosed.

4. 发明专利

CA2381268A1 SURGICAL BONE SCREW 未知
公开(公告)号：CA2381268A1
公开(公告)日：2000-10-12
申请号：CA2381268
申请日：2000-04-03
申请人： OSTEOTECH INC
发明人： LUKS HOWARD J , ROSENTHAL DANIEL E , MARTZ ERIK O , MORRIS JOHN W , KAES DAVID R , BOYLE JOHN W , SHIMP LAWRENCE A
IPC分类号： A61B17/86
摘要： An interference screw suitable for surgical use is provided. The interferenc e screw is constructed from bone and includes an elongated body having an oute r threaded surface, a tapered insertion end and a central throughbore. Inserti on tool engaging structure is formed along the walls defining the throughbore. The insertion tool engaging structure extends from the proximal end of the elongated body over a substantial portion of the length of the elongated bod y. The insertion tool engaging structure functions to distribute the forces required to insert the interference screw throughout the body of the interference screw to prevent fracturing of the interference screw during insertion into bone.

5. 发明专利

CA2637607C POLYURETHANES FOR OSTEOIMPLANTS 未知
公开(公告)号：CA2637607C
公开(公告)日：2013-03-19
申请号：CA2637607
申请日：2007-01-19
申请人： OSTEOTECH INC
发明人： KNAACK DAVID , WINTERBOTTOM JOHN , KAES DAVID R , BOYCE TODD M , SHIMP LAWRENCE A
IPC分类号： A61F2/28 , C08G18/10 , C08G18/38 , C08G18/64 , C08G18/73 , C08G18/77 , C08G18/79 , C08K3/00
摘要： Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.

6. 发明专利

TR200200578T2 未知
公开(公告)号：TR200200578T2
公开(公告)日：2003-09-22
申请号：TR200200578
申请日：2000-06-08
申请人： OSTEOTECH INC
发明人： BOYLE JOHN W , SHIMP LAWRENCE A , KAES DAVID R , MORRIS JOHN W , MARTZ ERIK O , BOYCE TODD M , DAUGHERTY MARK
IPC分类号： A61F2/00 , A61F2/28 , A61F2/30 , A61F2/44 , A61F2/46
摘要： A ramp-shaped intervertebral implant is disclosed. The implant has a body having a first end, a second end, a top surface and a bottom surface. At least one of the top and bottom surfaces is tapered and converges towards the second end of the body. An opening extends through the body and has one end opening onto the top surface of the implant and the other end opening onto the bottom surface of the implant. The implant can be formed from the diaphysis or metaphysis of a long bone, wherein the intramedullary canal of the long bone defines the opening. Alternately, the implant can be made from any biocompatible material having the requisite strength requirement.

7. 发明专利

AU2002360496A8 Spinal intervertebral implant, interconnections for such implant and processes for making 未知
公开(公告)号：AU2002360496A8
公开(公告)日：2003-06-17
申请号：AU2002360496
申请日：2002-12-05
申请人： OSTEOTECH INC
发明人： BOYCE TODD M , WINTERBOTTOM JOHN M , MARTZ ERIK O , SHIMP LAWERENCE A , KAES DAVID R
IPC分类号： A61F2/00 , A61F2/28 , A61F2/30 , A61F2/44 , A61F2/46
摘要： A cortical bone implant is formed of two or more planks of bone which are connected with one or more offset pins. The pins may be right circular cylinders inserted into a corresponding offset bore which offset bends the inserted pin. The bending creates compression and tensile loads in the pin which loads creates friction compression forces on the planks connecting them to the pins by friction. The pins may have different shapes to form offset configurations in place of the offset bores for friction attachment to the planks. The implants may be formed of flat or L-shaped planks or bones formed into other shapes including interlocking arrangements. Processes and fixtures are disclosed for forming the pins, planks and implants. Various embodiments of the pins, planks, implants and processes are disclosed.

8. 发明专利

AU4067800A Surgical bone screw 未知
公开(公告)号：AU4067800A
公开(公告)日：2000-10-23
申请号：AU4067800
申请日：2000-04-03
申请人： OSTEOTECH INC
发明人： LUKS HOWARD J , BOYLE JOHN W , SHIMP LAWRENCE A , KAES DAVID R , MORRIS JOHN W , MARTZ ERIK O , ROSENTHAL DANIEL E
IPC分类号： A61B17/86
摘要： An interference screw suitable for surgical use is provided. The interference screw is constructed from bone and includes an elongated body having an outer threaded surface, a tapered insertion end and a central throughbore. Insertion tool engaging structure is formed along the walls defining the throughbore. The insertion tool engaging structure extends from the proximal end of the elongated body over a substantial portion of the length of the elongated body. The insertion tool engaging structure functions to distribute the forces required to insert the interference screw throughout the body of the interference screw to prevent fracturing of the interference screw during insertion into bone.

9. 发明专利

CA2637606C POROUS OSTEOIMPLANT 未知
公开(公告)号：CA2637606C
公开(公告)日：2013-03-19
申请号：CA2637606
申请日：2007-01-19
申请人： OSTEOTECH INC
发明人： SHIMP LARRY , WINTERBOTTOM JOHN , KAES DAVID R , BELANEY RYAN M , BHATTACHARYYA SUBHABRATA
IPC分类号： A61F2/28
摘要： The invention is directed toward porous composites for application to a bone defect site to promote new bone growth. The inventive porous composites comprise a biocompatible polymer and a plurality of particles of bone-derived material, inorganic material, bone substitute material or composite material. In certain embodiments, the porous composites are prepared using a method that includes a supercritical fluid (e.g., supercritical carbon dioxide) treatment. The invention also discloses methods of using these composites as bone void fillers.

10. 发明专利

AU2002340306A1 Bone implant and insertion tools 未知
公开(公告)号：AU2002340306A1
公开(公告)日：2003-05-12
申请号：AU2002340306
申请日：2002-10-28
申请人： OSTEOTECH INC
发明人： WINTERBOTTOM JOHN , KAES DAVID R , ROSENTHAL DANIEL EVAN , MARTZ ERIK O
IPC分类号： A61B17/28 , A61F2/00 , A61F2/28 , A61F2/30 , A61F2/44 , A61F2/46
摘要： Spinal and other implants may be bone or synthetic material shaped as rings, C-shaped or rectangular and so on and also may have serrated wedge shaped top and bottom surfaces to match the disc space lordosis of adjacent ertebra and so on. The implants have one or more recesses aligned in an insertion direction at either or both outer peripheral sides of the implant. In a ring implant, e.g., formed from a transverse slice of the diaphysis of a long bone or otherwise, the recesses are aligned overlying the opposing sides of the ring parallel to the insertion direction, which sides are stronger than the more central region overlying and aligned with a central chamber in the implant. The alignment ith the opposing sides minimizes damage to the implant at the weaker more central region in response to implant insertion forces. One or two spaced recesses on opposite sides of an implant have surface(s) transverse to the insertion direction receive the tips of implant insertion gripping jaws for receiving an insertion load imparted by the tips. The recesses may have gripping surfaces extending in the insertion direction, which may be anterior/posterior or at an angle to the anterior/posterior direction for insertion laterally or anterior/laterally to the anterior/posterior direction. Such an implant may be non-bone and may be used to support or fuse bone not limited to the spine. Various embodiments of insertion tools and implants are disclosed.

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