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51. 发明申请

US20050069866A1 Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use 有权
标题翻译：猿猴腺病毒核酸和氨基酸序列，含有其的载体和使用方法
公开(公告)号：US20050069866A1
公开(公告)日：2005-03-31
申请号：US10494364
申请日：2002-11-20
申请人： James Wilson , Guangping Gao , Soumitra Roy
发明人： James Wilson , Guangping Gao , Soumitra Roy
IPC分类号： C12N15/09 , A61K39/00 , A61K48/00 , A61P37/04 , A61P43/00 , C07K14/025 , C07K14/075 , C07K14/08 , C07K14/145 , C07K14/16 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N7/00 , C12N7/04 , C12N15/33 , C12N15/861 , C12P21/02 , C12Q1/70 , C07H21/04 , C12N15/86
CPC分类号： A61K39/235 , A61K39/00 , A61K48/00 , A61K2039/525 , A61K2039/5256 , A61K2039/57 , C07K14/005 , C12N7/00 , C12N15/86 , C12N2710/10022 , C12N2710/10321 , C12N2710/10322 , C12N2710/10343 , C12N2710/10362 , C12N2710/20022 , C12N2740/16122 , C12N2740/17022 , C12N2750/14122 , C12N2760/14134 , C12N2760/16134 , C12N2760/20122 , C12N2830/002 , C12N2830/55
摘要： A recombinant vector comprises simian adenovirus sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.
摘要翻译：重组载体包含猿猴腺病毒序列和在调节序列控制下的异源基因。还公开了表达猿腺病毒基因的细胞系。提供了使用载体和细胞系的方法。

52. 发明申请

US20050044259A1 Resolving crossing requests in multi-node configurations 有权
标题翻译：在多节点配置中解决交叉请求
公开(公告)号：US20050044259A1
公开(公告)日：2005-02-24
申请号：US10917682
申请日：2004-08-13
申请人： James Wilson , Wolf-Dietrich Weber
发明人： James Wilson , Wolf-Dietrich Weber
IPC分类号： G06F12/08 , G06F12/00 , G06F13/42 , G06F15/16 , G06F15/167 , G06F15/17 , G06F15/173 , G06F15/177 , H04L29/08
CPC分类号： G06F12/0817 , G06F12/0813 , G06F12/0831 , G06F15/17
摘要： A method for communicating between nodes of a plurality of nodes is disclosed. Each node includes a plurality of processors and an interconnect chipset. The method issues a request for data from a processor in a first node and passes the request for data to other nodes through an expansion port (or scalability port). The method also starts an access of a memory in response to the request for data and snoops a processor cache of each processor in each node. The method accordingly identifies the location of the data in either the processor cache or memory in the node having the processor issuing the request or in a processor cache or memory of another node. A method for requesting data between two directly coupled nodes in a router system is also disclosed. A method for requesting data between three or more nodes in an interconnect system is also disclosed. A method for resolving crossing cases in an interconnect system is also disclosed. An interconnect system for coupling nodes directly or through a protocol engine is also disclosed.
摘要翻译：公开了一种在多个节点的节点之间进行通信的方法。每个节点包括多个处理器和互连芯片组。该方法向第一个节点中的处理器发出数据请求，并通过扩展端口（或可扩展端口）将数据请求传递给其他节点。该方法还响应于对数据的请求并且监听每个节点中的每个处理器的处理器高速缓存，开始访问存储器。因此，该方法识别在具有处理器发出请求的节点中的处理器高速缓存或存储器中的数据的位置，或者在另一节点的处理器高速缓存或存储器中。还公开了一种在路由器系统中的两个直接耦合节点之间请求数据的方法。还公开了一种在互连系统中的三个或更多节点之间请求数据的方法。还公开了一种用于解决互连系统中的交叉案例的方法。还公开了用于直接或通过协议引擎耦合节点的互连系统。

53. 发明申请

US20050021910A1 Accessing memory and processor caches of nodes in multi-node configurations 有权
标题翻译：访问多节点配置中节点的内存和处理器缓存
公开(公告)号：US20050021910A1
公开(公告)日：2005-01-27
申请号：US10917815
申请日：2004-08-13
申请人： James Wilson , Wolf-Dietrich Weber
发明人： James Wilson , Wolf-Dietrich Weber
IPC分类号： G06F12/08 , G06F12/00 , G06F13/42 , G06F15/16 , G06F15/167 , G06F15/17 , G06F15/173 , G06F15/177 , H04L29/08
CPC分类号： G06F12/0817 , G06F12/0813 , G06F12/0831 , G06F15/17
摘要： A method for communicating between nodes of a plurality of nodes is disclosed. Each node includes a plurality of processors and an interconnect chipset. The method issues a request for data from a processor in a first node and passes the request for data to other nodes through an expansion port (or scalability port). The method also starts an access of a memory in response to the request for data and snoops a processor cache of each processor in each node. The method accordingly identifies the location of the data in either the processor cache or memory in the node having the processor issuing the request or in a processor cache or memory of another node. A method for requesting data between two directly coupled nodes in a router system is also disclosed. A method for requesting data between three or more nodes in an interconnect system is also disclosed. A method for resolving crossing cases in an interconnect system is also disclosed. An interconnect system for coupling nodes directly or through a protocol engine is also disclosed.
摘要翻译：公开了一种在多个节点的节点之间进行通信的方法。每个节点包括多个处理器和互连芯片组。该方法向第一个节点中的处理器发出数据请求，并通过扩展端口（或可扩展端口）将数据请求传递给其他节点。该方法还响应于对数据的请求并且监听每个节点中的每个处理器的处理器高速缓存，开始访问存储器。因此，该方法识别在具有处理器发出请求的节点中的处理器高速缓存或存储器中的数据的位置，或者在另一节点的处理器高速缓存或存储器中。还公开了一种在路由器系统中的两个直接耦合节点之间请求数据的方法。还公开了一种在互连系统中的三个或更多节点之间请求数据的方法。还公开了一种用于解决互连系统中的交叉案例的方法。还公开了用于直接或通过协议引擎耦合节点的互连系统。

54. 发明申请

US20050014262A1 Adeno-associated virus (aav) serotype 9 sequences, vectors containing same, and uses therefor 有权
标题翻译：腺相关病毒（aav）血清型9序列，含有其的载体及其用途
公开(公告)号：US20050014262A1
公开(公告)日：2005-01-20
申请号：US10496799
申请日：2002-11-12
申请人： Guangping Gao , James Wilson , Mauricio Alvira
发明人： Guangping Gao , James Wilson , Mauricio Alvira
IPC分类号： C12N15/09 , A61K31/7088 , A61K35/76 , A61K48/00 , C07K14/015 , C07K14/075 , C12N20060101 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N7/00 , C12N7/01 , C12N15/85 , C12N15/86 , C12N15/861 , C12N15/864
CPC分类号： C07K14/005 , C12N15/86 , C12N2750/14122 , C12N2750/14143
摘要： Sequences of a serotype 9 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. AAV9-mediated delivery of therapeutic and immunogenic genes is also provided.
摘要翻译：提供血清型9腺相关病毒和含有这些序列的载体和宿主细胞的序列。还描述了在生产rAAV颗粒中使用这种宿主细胞和载体的方法。还提供AAV9介导的治疗和免疫原性基因的递送。

55. 发明授权

US06714976B1 Systems and methods for monitoring distributed applications using diagnostic information 有权
标题翻译：使用诊断信息监控分布式应用程序的系统和方法
公开(公告)号：US06714976B1
公开(公告)日：2004-03-30
申请号：US09368270
申请日：1999-08-03
申请人： James Wilson , Neeraj Agarwal , Gary Fernandez , Murtaza Doctor , Ken Kane , Albert Briner , Sehkar Muddana , Pieter deGroot , John Lyon-Smith , Scott Mendel
发明人： James Wilson , Neeraj Agarwal , Gary Fernandez , Murtaza Doctor , Ken Kane , Albert Briner , Sehkar Muddana , Pieter deGroot , John Lyon-Smith , Scott Mendel
IPC分类号： G06F15173
CPC分类号： H04L41/00 , H04L29/06 , H04L43/00 , H04L43/10 , H04L43/12 , H04L43/16 , H04L67/42
摘要： Systems and methods for automated monitoring and management of distributed applications, client/server databases, networks and systems across heterogeneous environments. Distributed, automated intelligent monitoring agents use embedded sensing technology which is knowledgeable of application protocols, to monitor continuously the network environment in real time. To this end, the monitoring agent can be located on each client and server in the network. The monitoring agent can couple to the communications stack for monitoring the data that is being passed between the client and the network, of a server in the network. The data can be collected and employed for trouble shooting trend analysis, resource planning, security auditing, and accounting as well as other applications. Also included is a controller for remotely coordinating the data gathering process from the various clients and servers.
摘要翻译：分布式应用程序，异构环境中的客户端/服务器数据库，网络和系统的自动监控和管理的系统和方法。分布式自动化智能监控代理使用了熟悉应用协议的嵌入式传感技术，实时监控网络环境。为此，监控代理可以位于网络中的每个客户端和服务器上。监视代理可以耦合到通信栈以监视网络中的服务器在客户端和网络之间传递的数据。数据可以收集并用于故障排除趋势分析，资源规划，安全审计，会计以及其他应用。还包括一个用于从各种客户端和服务器远程协调数据收集过程的控制器。

56. 发明授权

US5625358A Digital phase-locked loop utilizing a high order sigma-delta modulator 失效
标题翻译：采用高阶Σ-Δ调制器的数字锁相环
公开(公告)号：US5625358A
公开(公告)日：1997-04-29
申请号：US403291
申请日：1995-03-14
申请人： James Wilson , Ronald A. Cellini
发明人： James Wilson , Ronald A. Cellini
IPC分类号： H03H17/06 , H03L7/08 , H03L7/093 , H03L7/099 , H03M1/12 , H03M3/02 , H03M7/36
CPC分类号： H03H17/0614 , H03H17/0657 , H03H17/0664 , H03L7/08 , H03L7/093 , H03L7/0992 , H03M7/3022 , H03L2207/50
摘要： A method and apparatus for phase locking to an input signal and outputting a sigma-delta modulated control signal. The method and apparatus of the present invention provide a sigma-delta modulated control signal which can be utilized by any one of a decimator for decimating a digital data at a first data rate to a digital data at a second data rate and an interpolator for interpolating a digital data at a first data rate to a digital data at a second data rate. The decimator and the interpolator can be utilized in any one of an analog-to-digital converter, a digital-to-analog converter and a digital-to-digital converter. In one embodiment, a period of the input signal is determined and fed to a phase-locked loop which includes a sigma-delta modulator for providing the sigma-delta modulated control signal. The phase-locked loop also includes a phase detector for determining a phase and a frequency-difference between the input signal and a conversion signal generated by the phase-locked loop. The method and apparatus thus locks to the phase and the frequency of the input signal and provide a phase-locked sigma-delta-modulated control signal.
摘要翻译：一种用于相位锁定到输入信号并输出Σ-Δ调制控制信号的方法和装置。本发明的方法和装置提供了一种Σ-Δ调制控制信号，其可由抽取器中的任何一个利用，以第一数据速率将数字数据以第二数据速率抽取数字数据，以及用于内插的内插器以第一数据速率将数字数据以第二数据速率传送到数字数据。抽头和内插器可用于模数转换器，数 - 模转换器和数 - 数转换器中的任何一个。在一个实施例中，确定输入信号的周期并将其馈送到锁相环，该锁相环包括用于提供Σ-Δ调制控制信号的Σ-Δ调制器。锁相环还包括用于确定输入信号和由锁相环产生的转换信号之间的相位和频差的相位检测器。因此，该方法和装置锁定到输入信号的相位和频率，并提供锁相Σ-Δ调制控制信号。

57. 发明授权

US5485152A Analog to digital conversion using non-uniform sample rates 失效
标题翻译：使用不均匀采样率的模数转换
公开(公告)号：US5485152A
公开(公告)日：1996-01-16
申请号：US328560
申请日：1994-10-25
申请人： James Wilson , Ronald A. Cellini , James M. Sobol
发明人： James Wilson , Ronald A. Cellini , James M. Sobol
IPC分类号： H03M1/00 , H03H17/00 , H03H17/06 , H03L7/08 , H03L7/093 , H03L7/099 , H03M1/12 , H03M3/02 , H03M3/04 , H03M7/36
CPC分类号： H03H17/06 , H03H17/0614 , H03H17/0628 , H03L7/08 , H03L7/093 , H03L7/0992 , H03M3/498 , H03L2207/50
摘要： A method and apparatus for analog to digital conversion using sigma-delta modulation of the temporal spacing between digital samples. The method and apparatus of the present invention provides for sigma-delta modulation of the time base such that errors produced by non-uniform sampling are frequency-shaped to a region (i.e., shifted to higher frequencies) where they can be removed by conventional filtering techniques. In one embodiment, digital data is interpolated under control of a sigma-delta modulated frequency selection signal that represents, on average, the data rate of the digital data to be output by the converter and then decimated by a fixed ratio. The frequency selection signal is modulated using an n-th order m-bit sigma-delta modulator. Data thus emerges from the interpolation/decimation process at the sample rate selected by the n-th order m-bit sigma-delta modulator. The method and apparatus converts the data rate of an incoming digital data stream from an ADC to the data rate determined by the n-th order m-bit sigma-delta modulator.
摘要翻译：一种使用数字样本之间的时间间隔的Σ-Δ调制进行模数转换的方法和装置。本发明的方法和装置提供了时基的Σ-Δ调制，使得由非均匀采样产生的误差是频率形状的区域（即，转移到更高的频率），其中它们可以通过常规滤波被去除技术在一个实施例中，在Σ-Δ调制频率选择信号的控制下内插数字数据，该Δ-Δ调制频率选择信号平均表示要由转换器输出的数字数据的数据速率，然后以固定比率被抽取。使用第n级m位Σ-Δ调制器调制频率选择信号。数据因此从由第n级m比特Σ-Δ调制器选择的采样率的内插/抽取处理中出现。该方法和装置将来自ADC的输入数字数据流的数据速率转换为由第n位m位Σ-Δ调制器确定的数据速率。

58. 发明授权

US5312624A Drain treatment product and method of use 失效
标题翻译：排水处理产品及使用方法
公开(公告)号：US5312624A
公开(公告)日：1994-05-17
申请号：US51580
申请日：1993-04-22
申请人： Francis L. Richter , James Wilson , Daniel E. Pedersen
发明人： Francis L. Richter , James Wilson , Daniel E. Pedersen
IPC分类号： A61L2/18 , A61L11/00 , C09D5/34 , A01N25/08 , C11D17/00
CPC分类号： A61L11/00 , A61L2/18 , C09D5/34
摘要： A drain sanitizing article (9) for reducing microbiological activity in drain runoff areas having a housing (10), the housing having an inner wall (16) defining an inner opening (18) in the housing, an outer wall (12), and a bottom wall (14) defining a central cavity (15) in the housing (10), a tear strip (20) for destructibly removing the housing outer wall and a portion of the bottom wall (14), a handle (30) spanning the inner opening (18) of the housing (10) and joined to the inner wall (16) of said housing (10); and a chemical sanitizing agent (40).
摘要翻译：一种用于降低排水径流区域中的微生物活性的排水消毒物品（9），其具有壳体（10），所述壳体具有在所述壳体中限定内部开口（18）的内壁（16），外壁（12）在所述壳体（10）中限定中心空腔（15）的底壁（14），用于破坏所述壳体外壁和所述底壁（14）的一部分的破坏带（20），所述手柄壳体（10）的内部开口（18）并连接到所述壳体（10）的内壁（16）上。和化学消毒剂（40）。

59. 发明授权

US5113222A Reproduction apparatus with improved display for use in job set-up 失效
标题翻译：具有改进显示功能的再生设备用于工作设置
公开(公告)号：US5113222A
公开(公告)日：1992-05-12
申请号：US643878
申请日：1991-01-22
申请人： James Wilson , LinMarie Stephenson , Kenneth G. Corl
发明人： James Wilson , LinMarie Stephenson , Kenneth G. Corl
IPC分类号： G03G15/00
CPC分类号： G03G15/5016 , G03G15/502
摘要： In an electrostatographic reproduction apparatus there is provided an operator control panel having a display screen indicating certain standard selectable features for a copying operation including copy format (simplex to duplex, etc.), paper supply source, copy quality, magnification and exit location with plural displayed options for each feature. Keys and buttons are provided for altering the display to indicate a displayed selected option for each. For more complex operations the display may be changed to display various operator selectable special job level features for a copying operation available on a job level basis. The displaying is further alterable to display various operator selectable special page level features for a copying operation specific to reproducing a selected page of a multisheet document job. Thus a layered approach is provided in the series of displays from a standard features presentation which a casual user would be comfortable using, to a job level features presentation for a more complex reproduction at the job level, to a page level features presentation for designation of specific page level features for selection. User friendliness is enhanced with consistent use of indicia identifying a feature under consideration, selection of such feature and whether or not additional screens must be called up to further define that feature and further identifying other features which may not be chosen when a certain feature is chosen.
摘要翻译：在静电复原装置中，提供了一种操作员控制面板，其具有指示用于复印操作的某些标准可选择特征的显示屏幕，包括复制格式（单面到双面等），供纸源，复印质量，放大和退出位置与复数显示每个功能的选项。提供了键和按钮，用于更改显示以指示每个显示的选定选项。对于更复杂的操作，可以改变显示器以显示各种操作者可选择的特殊工作级别特征，用于在作业级别上可用的复印操作。显示可进一步改变以显示各种操作者可选择的特殊页面级别特征，用于复制特定于复制多页文档作业的所选页面的复印操作。因此，来自标准特征呈现的一系列显示器中的分层方法，临时用户将舒适地使用，将作业级别的功能呈现用于工作级别的更复杂的再现，到页面级特征呈现，用于指定特定的页面级别功能进行选择。通过一致地使用标识所考虑的特征的标记来增强用户友好性，选择这样的特征以及是否必须调用附加屏幕以进一步定义该特征，并且进一步识别当选择某个特征时可能不被选择的其他特征。

60. 发明授权

US09975980B2 Preparation of hydrophilic polymers of high mass by controlled radical polymerization 有权
公开(公告)号：US09975980B2
公开(公告)日：2018-05-22
申请号：US13876887
申请日：2011-09-27
申请人： Mathias Destarac , Aymeric Guinaudeau , Stéphane Mazieres , James Wilson
发明人： Mathias Destarac , Aymeric Guinaudeau , Stéphane Mazieres , James Wilson
IPC分类号： C08F2/38 , C08F271/00 , C08F293/00
CPC分类号： C08F271/00 , C08F2/38 , C08F293/005 , C08F2400/02
摘要： The present invention concerns a process for preparing a polymer comprising at least one gel polymerization step (E) in which the following are contacted: ethylenically unsaturated water-soluble monomers, the same or different; a source of free radicals adapted to the polymerization of the said monomers, typically a redox system; and a radical polymerization control agent, preferably comprising a thiocarbonylthio —S(C═S)— group; with a concentration of monomers in the reaction medium of step (E) sufficiently high to cause gelling of the medium if polymerization was conducted without the control agent.

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