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51. 发明授权

US5843139A Adaptive, performance-optimizing communication system for communicating with an implanted medical device 失效
标题翻译：用于与植入式医疗设备通信的自适应性能优化通信系统
公开(公告)号：US5843139A
公开(公告)日：1998-12-01
申请号：US816223
申请日：1997-03-12
申请人： Steven D. Goedeke , Gregory J. Haubrich , John G. Keimel , David L. Thompson
发明人： Steven D. Goedeke , Gregory J. Haubrich , John G. Keimel , David L. Thompson
IPC分类号： A61N1/08 , A61N1/37 , A61N1/372 , G06T1/60 , H04B1/69 , H04L1/00 , H04L27/04
CPC分类号： A61N1/37252 , A61N1/37223 , A61N1/37247 , A61N1/3727 , Y10S128/903
摘要： An adaptive, performance-optimizing communication system for communicating with an implanted medical device in which signals are transmitted and received in accordance with predetermined, interrelated operational parameters, such as transmission rate, transmitter power, and the like. Various aspects of system performance, including bit error rate in received signals, the strength of received signals, the signal-to-noise ratio of received signals, the presence of local RF noise and non-telemetry related RF signals, and the like, are dynamically monitored by the communication system, to determine whether predetermined system performance goals are being met. If it is determined that one or more system performance goals are not being met, one or more operational parameters may be automatically adjusted so that desired performance can be achieved.
摘要翻译：一种用于与植入式医疗装置进行通信的自适应性能优化通信系统，其中根据预定的相互关联的操作参数（诸如传输速率，发射机功率等）来发射和接收信号。系统性能的各个方面，包括接收信号中的误码率，接收信号的强度，接收信号的信噪比，本地RF噪声和非遥测相关RF信号的存在等等。由通信系统动态监视，以确定是否满足预定的系统性能目标。如果确定没有满足一个或多个系统性能目标，则可以自动调整一个或多个操作参数，从而可以实现期望的性能。

52. 发明授权

US5683432A Adaptive, performance-optimizing communication system for communicating with an implanted medical device 失效
标题翻译：用于与植入式医疗设备通信的自适应性能优化通信系统
公开(公告)号：US5683432A
公开(公告)日：1997-11-04
申请号：US584851
申请日：1996-01-11
申请人： Steven D. Goedeke , Gregory J. Haubrich , John G. Keimel , David L. Thompson
发明人： Steven D. Goedeke , Gregory J. Haubrich , John G. Keimel , David L. Thompson
IPC分类号： A61N1/08 , A61N1/37 , A61N1/372 , G06T1/60 , H04B1/69 , H04L1/00 , H04L27/04
CPC分类号： A61N1/37252 , A61N1/37223 , A61N1/37247 , A61N1/3727 , Y10S128/903
摘要： An adaptive, performance-optimizing communication system for communicating with an implanted medical device in which signals are transmitted and received in accordance with predetermined, interrelated operational parameters, such as transmission rate, transmitter power, and the like. Various aspects of system performance, including bit error rate in received signals, the strength of received signals, the signal-to-noise ratio of received signals, the presence of local RF noise and non-telemetry related RF signals, and the like, are dynamically monitored by the communication system, to determine whether predetermined system performance goals are being met. If it is determined that one or more system performance goals are not being met, one or more operational parameters may be automatically adjusted so that desired performance can be achieved.
摘要翻译：一种用于与植入式医疗装置进行通信的自适应性能优化通信系统，其中根据预定的相互关联的操作参数（诸如传输速率，发射机功率等）来发射和接收信号。系统性能的各个方面，包括接收信号中的误码率，接收信号的强度，接收信号的信噪比，本地RF噪声和非遥测相关RF信号的存在等等。由通信系统动态监视，以确定是否满足预定的系统性能目标。如果确定没有满足一个或多个系统性能目标，则可以自动调整一个或多个操作参数，从而可以实现期望的性能。

53. 依法登记的发明

USH1347H Audio feedback for implantable medical device instruments 失效
公开(公告)号：USH1347H
公开(公告)日：1994-08-02
申请号：US973358
申请日：1992-11-09
申请人： Daniel R. Greeninger , David L. Thompson
发明人： Daniel R. Greeninger , David L. Thompson
摘要： A method and apparatus for interpreting and displaying the status and diagnostic data of, and/or programming an implantable medical device is disclosed. The apparatus includes a microprocessor with multiple executable programs; data entry means, such as a keyboard or light pen; a display means such as a screen display and/or a printer; and may include a receiver and transmitter means for remote programming and interrogation of the implantable medical device. The apparatus further includes a stored audio signal to represent the status and diagnostic values of the implantable medical device.

54. 发明授权

US5233984A Implantable multi-axis position and activity sensor 失效
标题翻译：可植入多轴位置和活动传感器
公开(公告)号：US5233984A
公开(公告)日：1993-08-10
申请号：US677699
申请日：1991-03-29
申请人： David L. Thompson
发明人： David L. Thompson
IPC分类号： A61N1/365 , G01C9/06 , G01C9/18 , G01C9/20
CPC分类号： A61N1/36542 , G01C9/06 , G01C9/20 , A61N1/36535 , G01C2009/068 , G01C2009/182
摘要： A multi-axis, multi-purpose sensor for use with implantable medical devices, and for simultaneously detecting the patient's posture and activity level. The sensor includes a hermetically sealed, fluid-tight, bio-compatible housing. The housing is formed of a plurality of adjacently secured sides, and a plurality of side electrodes coupled to the sides. A central electrode is disposed at the geometric center of symmetry of the housing, to allow measurement of voltage changes between the central electrode and the side electrodes. A non-toxic electrically conductive electrolyte fills about half the housing, and immerses part of the central electrode and the side electrodes. The sensor further includes a low frequency bandpass filter for passing low frequency signals indicative of the patient's posture, and a high frequency bandpass filter for passing high frequency signals indicative of the patient's activity.
摘要翻译：一种用于可植入医疗设备的多轴多用途传感器，并用于同时检测患者的姿势和活动水平。该传感器包括密封的，流体密封的生物兼容的壳体。壳体由多个相邻固定的侧面以及耦合到该侧面的多个侧面电极形成。中心电极设置在壳体的几何对称中心处，以允许测量中心电极和侧电极之间的电压变化。无毒的导电电解质填充了壳体的大约一半，并且将中心电极和侧电极的一部分浸渍。传感器还包括用于传递指示患者姿势的低频信号的低频带通滤波器和用于通过表示患者活动的高频信号的高频带通滤波器。

55. 发明授权

US4949720A Apparatus for measuring the lead current in a pacemaker 失效
标题翻译：用于测量起搏器中引线电流的装置
公开(公告)号：US4949720A
公开(公告)日：1990-08-21
申请号：US246600
申请日：1988-09-20
申请人： David L. Thompson
发明人： David L. Thompson
IPC分类号： A61N1/362 , A61N1/08 , A61N1/37
CPC分类号： A61N1/3706 , A61N2001/083
摘要： Pacer lead current is assessed by monitoring the current through one of a plurality of output stage transistors.

56. 发明授权

US4890617A Dual chamber activity responsive pacer 失效
标题翻译：双室活动响应起搏器
公开(公告)号：US4890617A
公开(公告)日：1990-01-02
申请号：US125422
申请日：1987-11-25
申请人： H. Toby Markowitz , Kevin Prest-Berg , David L. Thompson
发明人： H. Toby Markowitz , Kevin Prest-Berg , David L. Thompson
IPC分类号： A61N1/365 , A61N1/368
CPC分类号： A61N1/36514 , A61N1/368
摘要： An activity responsive, rate adaptive pacer, which senses and paces in both the atrium and ventricle is disclosed. The pacing rate displayed by the pacer is determined by the sensed activity of the patient, the programmed lower rate, and the patient's atrial or sinus rate.
摘要翻译：公开了一种在心房和心室中感觉和起搏的活动响应速率自适应起搏器。起搏器显示的起搏速率由患者的感测活动，程序化的较低速率和患者的心房或窦速率决定。

57. 发明授权

US4476868A Body stimulator output circuit 失效
标题翻译：身体刺激器输出电路
公开(公告)号：US4476868A
公开(公告)日：1984-10-16
申请号：US184777
申请日：1980-09-08
申请人： David L. Thompson
发明人： David L. Thompson
IPC分类号： A61N1/365 , A61N1/372 , A61N1/36
CPC分类号： A61N1/365
摘要： A body implantable stimulator having an output capacitance. Provision is made to increase the charge rate of the capacitance for a predetermined period following an output stimulation signal.
摘要翻译：具有输出电容的身体植入式刺激器。提供了在输出刺激信号之后的预定时间段内增加电容的充电速率。

58. 发明授权

US4278422A Diffusion tube support collar 失效
标题翻译：扩散管支撑领
公开(公告)号：US4278422A
公开(公告)日：1981-07-14
申请号：US108553
申请日：1979-12-31
申请人： David L. Thompson
发明人： David L. Thompson
IPC分类号： C30B31/10 , F27D11/02 , H01L21/22 , F27B7/00 , B65D53/00 , F02F11/00
CPC分类号： F27D11/02 , C30B31/10
摘要： A collar for supporting and positioning a diffusion tube in a furnace used in the manufacture of semiconductors, integrated circuits and the like, is disclosed. The collar has a resilient core and an outer cover enclosing the core. The core and the cover are made of materials which readily withstand the normal operating temperatures of the furnace. The collar is dimensioned to tightly fit around a circumference of the diffusion tube, and to fit within an aperture provided in a support block of the furnace. The collar permits precise positioning of the diffusion tube relative to a helical heating coil provided in the furnace.
摘要翻译：公开了一种用于在用于半导体，集成电路等的制造中使用的炉中支撑和定位扩散管的套环。套环具有弹性芯和封闭芯的外盖。芯和盖由易于承受炉的正常操作温度的材料制成。套环的尺寸被设计成紧密地配合在扩散管的圆周周围，并且装配在设置在炉的支撑块中的孔内。套环允许扩散管相对于设置在炉中的螺旋加热线圈进行精确定位。

59. 发明授权

US4275737A Demand cardiac pacemaker having reduced polarity disparity 失效
标题翻译：需要减少极性差异的心脏起搏器
公开(公告)号：US4275737A
公开(公告)日：1981-06-30
申请号：US957813
申请日：1978-11-06
申请人： David L. Thompson , Marc T. Stein
发明人： David L. Thompson , Marc T. Stein
IPC分类号： A61N1/37 , A61N1/36
CPC分类号： A61N1/3704
摘要： A cardiac pacemaker of the type responsive to a natural heart activity for affecting the operation of the pacemaker. Circuitry is provided which has an essentially polarity independent degree of response to sensed signals. In a preferred embodiment, the circuitry includes a differential input and a differential output, the output signals being of opposite polarity but of the same absolute value and being representative of sensed signals.
摘要翻译：一种对自然心脏活动有反应作用的心脏起搏器，用于影响起搏器的运作。提供电路，其对感测到的信号具有基本上极性独立的响应程度。在优选实施例中，电路包括差分输入和差分输出，输出信号具有相反的极性，但具有相同的绝对值并且代表感测的信号。

60. 发明授权

US06968235B2 Enhanced method and apparatus to identify and connect a small diameter lead with a low profile lead connector 失效
标题翻译：增强的方法和设备，用于识别和连接小直径导线与低剖面导线连接器
公开(公告)号：US06968235B2
公开(公告)日：2005-11-22
申请号：US10137158
申请日：2002-04-30
申请人： Elisabeth L. Belden , Eric V. Blaha , Eric H. Bonde , Ryan Cobian , Steven D. Goedeke , Gregory J. Haubrich , Douglas N. Hess , Nels D. Nerison , John L. Sommer , David L. Thompson , Jonathan C. Werder
发明人： Elisabeth L. Belden , Eric V. Blaha , Eric H. Bonde , Ryan Cobian , Steven D. Goedeke , Gregory J. Haubrich , Douglas N. Hess , Nels D. Nerison , John L. Sommer , David L. Thompson , Jonathan C. Werder
IPC分类号： A61N1/37 , A61B5/00 , A61N1/02 , A61N1/05 , A61N1/372 , A61N1/375 , A61N1/39 , A61N1/34
CPC分类号： A61N1/37252 , A61B5/0031 , A61B2560/0219 , A61N1/025 , A61N1/37223 , A61N1/3752 , A61N2001/0585
摘要： The present invention provides a practical, multi-polar, in-line connector system for use in connecting implantable medical devices (IMD) and associated non-standard, low profile medical electrical leads. In addition, the present invention provides a system that uses tool less, frictional, sealed, compressive electrical connections for most or all of the electrical interconnections between an IMD and a low profile lead. A protective sleeve seals the lead connector to the non-standard port to prevent intrusion of body fluids therein. In addition, optional microchip-based circuitry coupled to the sleeve enables wireless communication and remote programming for diverse IMDs. Memory associated with the circuitry can store, update and reprogram a wide variety of information relevant to the IMD, the patient, and the attending physician, among others. For example, the microchip may be used to identify the lead type and characteristics, as well as other useful data.
摘要翻译：本发明提供了一种用于连接可植入医疗装置（IMD）和相关联的非标准低剖面医疗电引线的实用的多极直插式连接器系统。另外，本发明提供了一种系统，该系统对于IMD和低剖面导线之间的大部分或全部电互连使用较少的，摩擦的，密封的，压缩的电连接。保护套将引线连接器密封到非标准端口，以防止其中的体液侵入。此外，耦合到套管的可选的基于微芯片的电路可实现针对不同IMD的无线通信和远程编程。与电路相关联的存储器可以存储，更新和重新编程与IMD，患者和主治医师等相关的各种各样的信息。例如，微芯片可用于识别引线类型和特性，以及其他有用的数据。

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