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    • 51. 发明授权
    • Therapeutic and prophylactic agents for peptic ulcer
    • 消化性溃疡的治疗和预防剂
    • US4888417A
    • 1989-12-19
    • US867169
    • 1986-05-27
    • Yusei ShiragaChikara FukayaToshiaki AkiraMasakazu IwaiKazumasa YokoyamaMamoru TabataHiroshi FukuiShigeo TanakaYoshiro IgaTadakazu SuyamaKanemichi Okano
    • Yusei ShiragaChikara FukayaToshiaki AkiraMasakazu IwaiKazumasa YokoyamaMamoru TabataHiroshi FukuiShigeo TanakaYoshiro IgaTadakazu SuyamaKanemichi Okano
    • A61K31/12A61K31/70A61K36/54C07C49/242C07C49/255C07C49/647C07C49/743C07H15/18C07H15/203C07H15/207
    • C07C403/08C07C403/10C07C403/12C07H15/18C07H15/203C07C2101/16Y10S514/927
    • A therapeutic and prophylactic agent for peptic ulcers which contains as an active ingredient a compound of the general formula (I): ##STR1## wherein R.sub.1 represents hydrogen or =O; R.sub.2 represents hydrogen or --OR.sub.5 ; R.sub.3 represents hydrogen or --OR.sub.6 ; R.sub.4 represents --OR.sub.7 in the case of the absence of double bond; R.sub.5, R.sub.6 and R.sub.7 each represents hydrogen or an organic residue;X represents group (A):.dbd.C.dbd.CH--COR.sub.8 (A) or group (B): ##STR2## wherein R.sub.8 represents alkyl, and R.sub.9 and R.sub.10 each represents hydrogen or an organic residue; with the proviso that when X represents group (A), then R.sub.1 and R.sub.3 both represent hydrogen, R.sub.2 represents --OR.sub.5 ; R.sub.4 represents OR.sub.7 and the bond between the carbon atoms to which X is attached and the carbon atom to which R.sub.4 is attached is a single bond, and when X represents group (B), then R.sub.1 represents .dbd.O, R.sub.2 represents hydrogen, R.sub.3 represents --OR.sub.6 and the bond between the carbon atom to which X is attached and the carbon atom to which R.sub.4 is attached is a double bond, or a pharmaceutically acceptable salt thereof, or a compound of the general formula (II): ##STR3## wherein R.sub.11 represents hydrogen or an organic residue, and R.sub.12, R.sub.13 and R.sub.14 each represents an organic residue, or a pharmaceutically acceptable salt thereof. The compounds of the general formulae (I) and (II) can be derived from compounds contained in a hot water extract of cinnamon.
    • 含有作为活性成分的通式(I)的化合物的消化性溃疡的治疗和预防剂:其中R1表示氢或= O; R2代表氢或-OR5; R3表示氢或-OR6; 在不存在双键的情况下,R4代表-OR7; R5,R6和R7各自表示氢或有机残基; X表示基团(A):= C = CH-COR 8(A)或基团(B):其中R 8表示烷基,R 9和R 10各自表示氢或有机残基; 条件是当X表示基团(A)时,则R1和R3都表示氢,R2表示-OR5; R4表示OR7,X所连接的碳原子和与R4连接的碳原子之间的键为单键,当X表示基团(B)时,则R 1表示= O,R 2表示氢,R 3表示 -OR 6和X所连接的碳原子和与R 4连接的碳原子之间的键是双键,或其药学上可接受的盐或通式(II)的化合物:( II)其中R 11表示氢或有机残基,R 12,R 13和R 14各自表示有机残基或其药学上可接受的盐。 通式(I)和(II)的化合物可以衍生自肉桂热水提取物中所含的化合物。
    • 60. 发明申请
    • Thermally Conductive Silicone Rubber Composition
    • 导热硅橡胶组合物
    • US20090230348A1
    • 2009-09-17
    • US11909932
    • 2006-03-27
    • Hiroshi Fukui
    • Hiroshi Fukui
    • C09K5/00
    • C08L83/04C08G77/14C08G77/18C08G77/20C08K3/22C08K9/06C08L83/00
    • A thermally conductive silicone rubber composition comprising: (A) an organopolysiloxane with the exception of below-given components (C) and (E); (B) a thermally conductive filler; (C) a specific organopolysiloxane; (D) a curing agent; (E) a resin-like organopolysiloxane; and (F) a silane compound showing no affinity to aforementioned component (A), wherein component (E) is contained in an amount of 2 to 10 mass % per sum of components (A) and (E), and wherein said component (F) is contained in an amount sufficient for coating 1 to 70% of the entire surface of component (B) determined from the contents of component (B) and the BET specific surface area of aforementioned component (B), demonstrates good handleability and possesses appropriate thixotropicity even when it contains a large amount of thermally conductive filler and when cured is capable of forming a thermally conductive silicone rubber characterized by good adhesive properties and elongation characteristics even without the use of a reinforcing filler.
    • 一种导热硅橡胶组合物,其包含:(A)除低于给定组分(C)和(E)之外的有机聚硅氧烷; (B)导热填料; (C)特定有机聚硅氧烷; (D)固化剂; (E)树脂状有机聚硅氧烷; 和(F)对上述组分(A)不具有亲和性的硅烷化合物,其中组分(E)的含量相对于组分(A)和(E)的总和为2至10质量%,并且其中所述组分 F)的含量足以涂布由组分(B)的含量和上述组分(B)的BET比表面积确定的组分(B)的整个表面的1至70%,表现出良好的可操作性,并具有 即使在含有大量的导热性填料时也具有合适的触变性,并且固化时,即使不使用增强填料也能够形成特征在于良好的粘合性和伸长特性的导热性硅橡胶。