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51. 发明授权

US07009803B2 Method and apparatus of dual stage servo control for track following in a hard disk drive 失效
标题翻译：用于在硬盘驱动器中跟踪的双级伺服控制的方法和装置
公开(公告)号：US07009803B2
公开(公告)日：2006-03-07
申请号：US10886171
申请日：2004-07-06
申请人： Vinod Sharma , Hyung Jai Lee , Dong Jun Lee
发明人： Vinod Sharma , Hyung Jai Lee , Dong Jun Lee
IPC分类号： G11B5/596
CPC分类号： G11B5/5552 , G11B5/596
摘要： The invention operates two control paths. The micro-actuator control stimulates the micro-actuator. The voice coil motor control path includes the voice coil motor control generating a voice coil control signal, notch filtered to remove at least one significant excitation resonance for a notch filtered voice coil control signal. Amplifying the notch filtered voice coil control signal by a tuning gain stimulates the voice coil motor.A decoupling feedback filter uses the micro-actuator control signal to create a decoupling feedback signal used to decouple the two control paths. A track following command, with PES removed, directs the micro-actuator control. The voice coil motor control is directed by the track following command, with both PES and decoupling feedback signal removed.Preferably, the servo-controller digitally supports the elements of the invention. Implementing the method may preferably include the servo-controller program system residing in an accessibly coupled memory.The invention includes optimizing an implementation within the hard disk drive. The optimization may be part of the manufacturing process for the hard disk drive. The invention includes the hard disk drive as the product of that manufacturing process.
摘要翻译：本发明操作两个控制路径。微致动器控制激励微致动器。音圈电机控制路径包括产生音圈控制信号的音圈电机控制信号，对陷波滤波音圈控制信号进行陷波滤波以去除至少一个重要的激励谐振。通过调谐增益放大陷波滤波的音圈控制信号可以刺激音圈电机。去耦反馈滤波器使用微致动器控制信号来产生用于去耦合两个控制路径的去耦反馈信号。一个跟踪命令，取消了PES，指示微执行器控制。音圈电机控制由跟踪跟踪命令指导，PES和去耦反馈信号都消除。优选地，伺服控制器以数字方式支持本发明的元件。实施该方法可以优选地包括驻留在可访问耦合的存储器中的伺服控制器程序系统。本发明包括优化硬盘驱动器内的实现。优化可能是硬盘驱动器的制造过程的一部分。本发明包括硬盘驱动器作为该制造过程的产物。

52. 发明申请

US20050266576A1 Identifying patients at risk for life threatening arrhythmias 失效
标题翻译：识别处于危及生命的心律失常风险的患者
公开(公告)号：US20050266576A1
公开(公告)日：2005-12-01
申请号：US11157549
申请日：2005-06-21
申请人： Orhan Soykan , Amy Dearking , Timothy Robinson , Walter Olson , Vinod Sharma
发明人： Orhan Soykan , Amy Dearking , Timothy Robinson , Walter Olson , Vinod Sharma
IPC分类号： G01N33/68 , G06F19/00 , G01N33/00
CPC分类号： G01N33/6893 , G01N2800/326
摘要： The invention is a method for identifying proteins associated with sudden cardiac death (SCD) and for assessing a patient's risk of SCD by determining the amount of one or more SCD-associated proteins in the patient. Typically, the patient submits a sample, such as a blood sample, which is tested for one or more SCD-associated proteins. Based upon the results of the tests, the patient's risk of SCD may be assessed.
摘要翻译：本发明是鉴定与心脏猝死相关的蛋白质（SCD）的方法，并且通过确定患者中一种或多种与SCD相关的蛋白质的量来评估患者的SCD风险。通常，患者提交样品，例如血液样品，其被测试一种或多种与SCD相关的蛋白质。根据测试结果，可以评估患者SCD的风险。

53. 发明申请

US20050091914A1 Antioxidant composition for motor gasoline 有权
标题翻译：汽油汽油的抗氧化剂组合物
公开(公告)号：US20050091914A1
公开(公告)日：2005-05-05
申请号：US10922659
申请日：2004-08-20
申请人： Anurag Gupta , Suresh Puri , Subhash Chand , Vinod Sharma , Rajagopal Manoharan , Rameshwar Prashad , Niranjan Raje , Akhilesh Bratnagar
发明人： Anurag Gupta , Suresh Puri , Subhash Chand , Vinod Sharma , Rajagopal Manoharan , Rameshwar Prashad , Niranjan Raje , Akhilesh Bratnagar
IPC分类号： C10L1/14 , C10L1/18 , C10L1/22
CPC分类号： C10L1/143 , C10L1/1832 , C10L1/223 , C10L1/238
摘要： An antioxidant composition effective for stabilizing gasoline and gasoline components contains from approximately 50-95% by weight of at least one Mannich base and from approximately 5-50% by weight of at least one amine. The Mannich base is derived from p-substituted phenols or from cashew nut shell liquid.
摘要翻译：用于稳定汽油和汽油组分的抗氧化剂组合物含有约50-95％重量的至少一种曼尼希碱和约5-50％重量的至少一种胺。曼尼希碱基来自对取代的酚类或来自腰果壳的液体。

54. 发明授权

US06747843B2 Ramp design for reducing read-write head track positioning errors 失效
标题翻译：斜坡设计可减少读写头轨迹定位误差
公开(公告)号：US06747843B2
公开(公告)日：2004-06-08
申请号：US10107387
申请日：2002-03-26
申请人： Vinod Sharma , Joseph Chang , Hyung Jai Lee
发明人： Vinod Sharma , Joseph Chang , Hyung Jai Lee
IPC分类号： G11B554
CPC分类号： G11B21/22 , G11B5/54
摘要： The invention includes a method of A wipping part of the load ramp is a convex finger crossing the read-write head path of motion with respect to a lifting tab engagably moving across the loading ramp.
摘要翻译：本发明包括一种方法，其中一部分负载斜坡是一凸凸指，该凸指相对于一可提升平板移动穿过该加载斜坡的一提升片而与该移动读写头相交。

55. 发明授权

US06609209B1 Method and apparatus for reducing the power consumed by a processor by gating the clock signal to pipeline stages 有权
标题翻译：用于通过将时钟信号门控到流水线级来降低处理器消耗的功率的方法和装置
公开(公告)号：US06609209B1
公开(公告)日：2003-08-19
申请号：US09474461
申请日：1999-12-29
申请人： Vivek Tiwari , Vinod Sharma , Sivakumar Makineni , Suri B. Medapati
发明人： Vivek Tiwari , Vinod Sharma , Sivakumar Makineni , Suri B. Medapati
IPC分类号： G06F132
CPC分类号： G06F9/3869 , G06F1/3228 , G06F1/3243 , G06F9/3861 , Y02D10/152
摘要： A processor includes a pipeline having first and second stages and a shift register having first and second latches. An interface circuit is used to provide a clock signal from a clock signal line to the first and second stages based, at least in part, on first and second bits to be stored in the first and second latches, respectively.
摘要翻译：处理器包括具有第一和第二级的管线和具有第一和第二锁存器的移位寄存器。接口电路用于至少部分地基于要存储在第一和第二锁存器中的第一和第二位来从时钟信号线向第一和第二级提供时钟信号。

56. 发明授权

US08734780B2 Methods for treating cardiac pacing conditions 有权
标题翻译：治疗心脏起搏病症的方法
公开(公告)号：US08734780B2
公开(公告)日：2014-05-27
申请号：US13096135
申请日：2011-04-28
申请人： Vinod Sharma , Xiaohong Qiu
发明人： Vinod Sharma , Xiaohong Qiu
IPC分类号： A61K31/7088 , A61K35/00 , A61P9/00 , C12N5/10
CPC分类号： C12N15/86 , A61K35/13 , A61K48/005 , A61K48/0075 , C07K14/4705 , C12N2750/14143
摘要： The method may include administering to a subject in need thereof an effective amount of an HCN polynucleotide. The HCN polynucleotide includes a nucleotide sequence encoding an HCN polypeptide having channel activity. The amino acid sequence of the HCN polypeptide and the amino acid sequence of a reference polypeptide have at least 80% identity, where the reference polypeptide begins with an amino acid selected from amino acids 92-214 and ends with an amino acid selected from amino acids 723-1188 of SEQ ID NO:8. An example of a reference polypeptide is amino acids 214-723 of SEQ ID NO:8. The HCN polynucleotide may be DNA or RNA.
摘要翻译：该方法可以包括向有需要的受试者施用有效量的HCN多核苷酸。 HCN多核苷酸包括编码具有通道活性的HCN多肽的核苷酸序列。 HCN多肽的氨基酸序列和参考多肽的氨基酸序列具有至少80％的同一性，其中参考多肽以选自氨基酸92-214的氨基酸开始，并以选自氨基酸的氨基酸结束 SEQ ID NO：8的723-1188。参考多肽的实例是SEQ ID NO：8的氨基酸214-723。 HCN多核苷酸可以是DNA或RNA。

57. 发明授权

US08642747B2 Genetic modification of targeted regions of the cardiac conduction system 有权
标题翻译：心脏传导系统目标区域的遗传修饰
公开(公告)号：US08642747B2
公开(公告)日：2014-02-04
申请号：US13224593
申请日：2011-09-02
申请人： Vinod Sharma , Walter H. Olson
发明人： Vinod Sharma , Walter H. Olson
IPC分类号： A61K48/00 , C12N15/00 , C07H21/02
CPC分类号： C12N15/86 , A61K38/177 , A61K48/00 , A61K48/005 , C12N2750/14143
摘要： Disclosed are methods and systems for preventing or treating cardiac dysfunction, particularly cardiac pacing dysfunction by genetic modification of the conduction system of the heart. In one embodiment, the invention provides a method of genetically modifying the cells by delivering to the cells one or more coding sequence in a genetic construct capable of modifying the expression of ion channels of the cells.
摘要翻译：公开了通过心脏传导系统的遗传修饰来预防或治疗心脏功能障碍，特别是心脏起搏功能障碍的方法和系统。在一个实施方案中，本发明提供了通过向细胞递送能够修饰细胞的离子通道的表达的遗传构建体中的一个或多个编码序列来遗传修饰细胞的方法。

58. 发明授权

US08639323B2 System and apparatus to monitor biopacemaker maturation 有权
标题翻译：监测生物空间成熟的系统和仪器
公开(公告)号：US08639323B2
公开(公告)日：2014-01-28
申请号：US12917062
申请日：2010-11-01
申请人： Vinod Sharma , Deborah A. Jaye , Daniel Sigg
发明人： Vinod Sharma , Deborah A. Jaye , Daniel Sigg
IPC分类号： A61N1/08
CPC分类号： A61N1/362 , A61B5/021 , A61B5/026 , A61B5/0468 , A61B5/14503 , A61B5/14542 , A61B5/4848 , A61B5/686 , A61B5/7232 , A61K48/005 , A61N1/3702 , A61N1/37247 , G06F19/00 , G06F19/3481 , G16H15/00 , G16H40/63
摘要： The present invention includes systems, devices, and methods relating to the monitoring of the functional maturation of biological interventions effecting cardiac pacing; the systems, devices, and methods including an implantable electronic pulse generator delivering artificial cardiac pacing; a means for halting the electronic pulse generator delivering artificial cardiac pacing at predetermined data collection intervals; and a sensor for recording and storing data on one or more intrinsic physiological parameters of cardiac pacing during the predetermined data collection intervals.
摘要翻译：本发明包括与影响心脏起搏的生物干预功能成熟的监测有关的系统，装置和方法; 所述系统，装置和方法包括递送人造心脏起搏的可植入电子脉冲发生器; 用于停止以预定的数据采集间隔递送人造心脏起搏的电子脉冲发生器的装置; 以及用于在预定数据收集间隔期间记录和存储关于心脏起搏的一个或多个固有生理参数的数据的传感器。

59. 发明授权

US08432848B2 Queued cooperative wireless networks configuration using rateless codes 有权
公开(公告)号：US08432848B2
公开(公告)日：2013-04-30
申请号：US12550177
申请日：2009-08-28
申请人： Neelesh B. Mehta , Vinod Sharma , Gaurav Bansal
发明人： Neelesh B. Mehta , Vinod Sharma , Gaurav Bansal
IPC分类号： H04B7/14
CPC分类号： H04B7/15 , H04B7/15592 , H04B7/2606 , H04L47/14 , H04W28/10
摘要： A system using cooperative communication with rateless codes is presented that uses communication transmission aspects of cooperative communication with rateless codes over Rayleigh fading channels and queuing aspects for buffering messages at intermediate relays. The system transmits a subsequent message while a current message is en route to the destination by receiving and buffering the current message in queues at intermediate relays. A relay with a best instantaneous communication link to the source may receive a message first and forward the received message to the destination. Alternatively, if inter-relay communication links are strong, all relays may cooperate simultaneously.

60. 发明授权

US08396539B2 Implantable medical device having optical fiber for sensing electrical activity 有权
标题翻译：具有用于感测电活动的光纤的可植入医疗装置
公开(公告)号：US08396539B2
公开(公告)日：2013-03-12
申请号：US11676128
申请日：2007-02-16
申请人： Vinod Sharma , Xiaohong Zhou
发明人： Vinod Sharma , Xiaohong Zhou
IPC分类号： A61B5/04
CPC分类号： A61B5/0071 , A61B5/0084 , A61B5/0452
摘要： An implantable medical device for optically sensing action potential signals in excitable body tissue. The device includes an elongated tubular lead body carrying an optical fiber extending from a proximal lead end to a distal lead end to position the optical fiber at a target site. The lead body additionally carries a conduit for dispensing a voltage-sensitive fluorescent dye into tissue surrounding the target site. The optical fiber transmits excitation light to the fluorescent dye to cause the dye to fluoresce with varying intensity as the transmembrane potentials of local tissue cells vary due to passing depolarization wavefronts. The optical fiber transmits the fluorescence signal to the device to generate an action potential signal or fiducial points of an action potential signal for use in accurately measuring and characterizing electrical activity of excitable tissue.
摘要翻译：一种用于在可兴奋的身体组织中光学感测动作电位信号的可植入医疗装置。该装置包括细长的管状引线体，其承载从近侧引线端延伸到远端引线端的光纤，以将光纤定位在目标部位。引线体还带有用于将电压敏感的荧光染料分配到靶区域周围的组织中的导管。光纤将激发光透射到荧光染料，以使得染料以不同的强度发荧光，因为局部组织细胞的跨膜电位由于通过去极化波前而变化。光纤将荧光信号传输到设备以产生动作电位信号或动作电位信号的基准点，用于精确测量和表征可兴奋组织的电活动。

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