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    • 42. 发明授权
    • Raman signal-enhancing structures for Raman spectroscopy and methods for performing Raman spectroscopy
    • 用于拉曼光谱的拉曼信号增强结构和用于进行拉曼光谱的方法
    • US07639354B2
    • 2009-12-29
    • US11701045
    • 2007-01-31
    • Shih-Yuan WangZhiyong Li
    • Shih-Yuan WangZhiyong Li
    • G01J3/44
    • G01J3/44G01N21/658
    • Raman systems include a radiation source, a radiation detector configured to detect Raman scattered radiation, and a Raman signal-enhancing structure. The Raman signal-enhancing structure includes a first layer of Raman signal-enhancing material, a substantially monomolecular layer of molecules disposed on at least a portion of the first layer of Raman signal-enhancing material, and a second layer of Raman signal-enhancing material disposed on at least a portion of the substantially monomolecular layer of molecules. The second layer of Raman signal-enhancing material is disposed on a side of the layer of molecules opposite the first layer of Raman signal-enhancing material. Methods of performing Raman spectroscopy include providing such a Raman signal-enhancing structure, providing an analyte on the Raman signal-enhancing structure, irradiating the analyte and the structure, and detecting Raman scattered radiation.
    • 拉曼系统包括辐射源,被配置为检测拉曼散射辐射的辐射检测器和拉曼信号增强结构。 拉曼信号增强结构包括第一层拉曼信号增强材料,设置在第一层拉曼信号增强材料的至少一部分上的基本上单分子层的分子,以及第二层拉曼信号增强材料 设置在分子的基本单分子层的至少一部分上。 第二层拉曼信号增强材料设置在与第一层拉曼信号增强材料相对的分子层的一侧。 执行拉曼光谱的方法包括提供这样的拉曼信号增强结构,在拉曼信号增强结构上提供分析物,照射分析物和结构,以及检测拉曼散射辐射。
    • 44. 发明申请
    • Raman and hyper-rman excitation using superlensing
    • 拉曼和超雷曼激发使用超透镜
    • US20070252980A1
    • 2007-11-01
    • US11413377
    • 2006-04-28
    • Shih-Yuan WangZhiyong Li
    • Shih-Yuan WangZhiyong Li
    • G01J3/44G01N21/65
    • G01J3/02G01J3/0208G01N21/658
    • Raman-enhancing structures include a layer of dielectric material, a superlens configured to focus electromagnetic radiation having a wavelength greater than about 100 nanometers to a two-dimensional focal area having linear dimensions less than about 100 nanometers on a surface of the layer of dielectric material, and at least two nanoparticles comprising a Raman-enhancing material disposed proximate the focal area. Additional Raman-enhancing structures include a layer of dielectric material, a layer of conductive material, and at least two nanoparticles comprising a Raman-enhancing material disposed on a second, opposite surface of the layer of dielectric material. The layer of conductive material has a plurality of apertures therethrough that are arranged in a two-dimensional array. Methods for conducting Raman spectroscopy are performed using such structures and systems.
    • 拉曼增强结构包括介电材料层,配置成将具有大于约100纳米的波长的电磁辐射聚焦到具有小于约100纳米的线性尺寸的二维聚焦区域的超薄膜在电介质材料层的表面上 以及至少两个纳米颗粒,其包含靠近焦点区域设置的拉曼增强材料。 附加的拉曼增强结构包括电介质材料层,导电材料层,以及至少两个包含拉曼增强材料的纳米颗粒,该拉曼增强材料设置在电介质材料层的第二相对表面上。 导电材料层具有以二维阵列布置的穿过其中的多个孔。 使用这种结构和系统进行拉曼光谱的方法。
    • 50. 发明授权
    • Electrically driven devices for surface enhanced raman spectroscopy
    • 用于表面增强拉曼光谱的电驱动装置
    • US08559003B2
    • 2013-10-15
    • US13384456
    • 2009-09-17
    • Huei Pei KuoShih-Yuan WangMin HuZhiyong LiAlexandre M. Bratkovski
    • Huei Pei KuoShih-Yuan WangMin HuZhiyong LiAlexandre M. Bratkovski
    • G01J3/44
    • G01N21/658B82Y15/00B82Y30/00
    • An electrically driven device for surface enhanced Raman spectroscopy includes a first electrode, a substrate positioned proximate to the first electrode, a plurality of cone shaped protrusions formed integrally with or on a substrate surface, a Raman signal-enhancing material coated on each protrusion, and a second electrode positioned relative to the first electrode at a predetermined distance. Each of the protrusions has a tip with a radius of curvature ranging from about 0.1 nm to about 100 nm. The second electrode is positioned relative to the first electrode such that the electrodes together produce an electric field when a voltage bias is applied therebetween. The electric field has a field distribution that creates a stronger field gradient at a region proximate to the tips than at other portions of the substrate.
    • 用于表面增强拉曼光谱的电驱动装置包括第一电极,靠近第一电极定位的基板,与基底表面一体地形成的多个锥形突起,涂覆在每个突起上的拉曼信号增强材料,以及 相对于第一电极以预定距离定位的第二电极。 每个突起具有具有约0.1nm至约100nm范围的曲率半径的尖端。 第二电极相对于第一电极定位,使得当在其之间施加电压偏置时,电极一起产生电场。 电场具有场分布,其在靠近尖端的区域处产生比在衬底的其它部分更强的场梯度。