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41. 发明授权

US09040905B2 Analysis device and analysis method 有权
公开(公告)号：US09040905B2
公开(公告)日：2015-05-26
申请号：US13884755
申请日：2011-11-08
申请人： Hisashi Nagano , Yasutaka Suzuki , Hideo Kashima , Yuichiro Hashimoto , Masuyuki Sugiyama , Masakazu Sugaya , Yasunori Doi , Koichi Terada
发明人： Hisashi Nagano , Yasutaka Suzuki , Hideo Kashima , Yuichiro Hashimoto , Masuyuki Sugiyama , Masakazu Sugaya , Yasunori Doi , Koichi Terada
IPC分类号： H01J49/04 , G01N1/22 , G01N1/02 , H01J49/00 , G01N33/00
CPC分类号： H01J49/0422 , G01N1/2211 , G01N1/2214 , G01N33/0057 , G01N2001/028 , H01J49/00 , H01J49/0036 , H01J49/04 , H01J49/0459 , H01J49/0468 , Y02A50/25
摘要： Provided is a technique of analyzing particles in real time while collecting and condensing the particles continuously. Gas and/or particles as a detection target substance that are attached to an authentication target 2 are removed by air flow from a blowing region 5. The removed sample is sucked and is condensed and sampled at a sampling region 10, and ions of the sample are generated at an ion source 21 and are then subjected to mass analysis at a mass analysis region 23. Determination of the obtained mass spectrum is made as to the presence or not of a mass spectrum derived from the detection target substance, and a monitor 27 displays a result thereof. Thereby, the detection target substance attached to the authentication target 2 can be detected continuously in real time, promptly and with a less error rate.

42. 发明授权

US08710430B2 Mass spectrometry method 有权
标题翻译：质谱法
公开(公告)号：US08710430B2
公开(公告)日：2014-04-29
申请号：US13527619
申请日：2012-06-20
申请人： Masuyuki Sugiyama , Yuichiro Hashimoto , Shun Kumano , Yohei Kawaguchi , Hidetoshi Morokuma
发明人： Masuyuki Sugiyama , Yuichiro Hashimoto , Shun Kumano , Yohei Kawaguchi , Hidetoshi Morokuma
IPC分类号： H01J49/42 , H01J49/26 , H01J49/00
CPC分类号： H01J49/4265 , H01J49/0009 , H01J49/0036
摘要： A mass spectrometry method that corrects the effects from space charge and that achieves both sensitivity and a dynamic range. The mass axis of the mass spectrum is corrected based on the counts of ions accumulated within the ion trap at the point in time each ion was extracted.
摘要翻译：一种校正空间电荷效应并实现灵敏度和动态范围的质谱法。基于在每个离子被提取的时间点内积聚在离子阱内的离子的计数校正质谱的质量轴。

43. 发明授权

US08686352B2 Systems and computer program products for mass spectrometry 有权
标题翻译：用于质谱的系统和计算机程序产品
公开(公告)号：US08686352B2
公开(公告)日：2014-04-01
申请号：US13468967
申请日：2012-05-10
申请人： Yohei Kawaguchi , Yuichiro Hashimoto , Masuyuki Sugiyama , Shun Kumano , Shuhei Hashiba , Masahito Togami
发明人： Yohei Kawaguchi , Yuichiro Hashimoto , Masuyuki Sugiyama , Shun Kumano , Shuhei Hashiba , Masahito Togami
IPC分类号： H01J49/26
CPC分类号： H01J49/0031 , H01J49/004
摘要： A mass spectrometry system is mounted with (1) an action planning module for determining a measurement schedule provided by a combination of an MS analysis and an MSn analysis (where n≧2) according to a measuring time provided previously; and (2) a mass spectrometry unit having a tandem mass spectrometry function for outputting a mass spectrum obtained by performing each measurement action constructing the measurement schedule.
摘要翻译：一种质谱系统安装有（1）动作计划模块，用于根据先前提供的测量时间确定由MS分析和MSn分析（其中n≥2）的组合提供的测量计划; 和（2）具有串联质谱分析功能的质谱分析装置，用于输出通过进行构成测定时间表的每个测定动作而得到的质谱。

44. 发明申请

US20120326027A1 MASS SPECTROMETRY METHOD 有权
标题翻译：质谱法
公开(公告)号：US20120326027A1
公开(公告)日：2012-12-27
申请号：US13527619
申请日：2012-06-20
申请人： Masuyuki SUGIYAMA , Yuichiro Hashimoto , Shun Kumano , Yohei Kawaguchi , Hidetoshi Morokuma
发明人： Masuyuki SUGIYAMA , Yuichiro Hashimoto , Shun Kumano , Yohei Kawaguchi , Hidetoshi Morokuma
IPC分类号： H01J49/26
CPC分类号： H01J49/4265 , H01J49/0009 , H01J49/0036
摘要： A mass spectrometry method that corrects the effects from space charge and that achieves both sensitivity and a dynamic range. The mass axis of the mass spectrum is corrected based on the counts of ions accumulated within the ion trap at the point in time each ion was extracted.
摘要翻译：一种校正空间电荷效应并实现灵敏度和动态范围的质谱法。基于在每个离子被提取的时间点内积聚在离子阱内的离子的计数校正质谱的质量轴。

45. 发明授权

US08560249B2 Dangerous substance detection system 有权
标题翻译：危险物质检测系统
公开(公告)号：US08560249B2
公开(公告)日：2013-10-15
申请号：US12903263
申请日：2010-10-13
申请人： Hisashi Nagano , Yasuaki Takada , Minoru Sakairi , Yuichiro Hashimoto , Masuyuki Sugiyama
发明人： Hisashi Nagano , Yasuaki Takada , Minoru Sakairi , Yuichiro Hashimoto , Masuyuki Sugiyama
IPC分类号： G01N31/00
CPC分类号： H01J49/0036 , G01N33/227 , H01J49/004
摘要： A method of quickly detecting a handmade explosive in a bottle with a low erroneous alarm frequency is provided. A sample gas generated from a bottle placed on a bottle placement space is sucked-in, and ions of the sample gas are generated by an ion source and subjected to mass analysis. The presence/absence of a mass spectrum derived from the handmade explosive is determined from an obtained mass spectrum, and the result thereof is displayed on a monitor, thereby quickly detecting the handmade explosive in the bottle or the handmade explosive adhering to the surface of the bottle at a low erroneous alarm frequency.
摘要翻译：提供了一种在低错误报警频率的瓶子中快速检测手工炸药的方法。将从放置在瓶放置空间的瓶子产生的样品气体吸入，并且通过离子源产生样品气体的离子并进行质量分析。从所获得的质谱确定来自手工炸药的质谱的存在/不存在，并将其结果显示在监视器上，从而快速检测瓶中的手工炸药或附着在表面上的手工炸药瓶子在低错误报警频率。

46. 发明申请

US20120298852A1 SYSTEMS AND COMPUTER PROGRAM PRODUCTS FOR MASS SPECTROMETRY 有权
标题翻译：用于质谱分析的系统和计算机程序产品
公开(公告)号：US20120298852A1
公开(公告)日：2012-11-29
申请号：US13468967
申请日：2012-05-10
申请人： Yohei Kawaguchi , Yuichiro Hashimoto , Masuyuki Sugiyama , Shun Kumano , Shuhei Hashiba , Masahito Togami
发明人： Yohei Kawaguchi , Yuichiro Hashimoto , Masuyuki Sugiyama , Shun Kumano , Shuhei Hashiba , Masahito Togami
IPC分类号： H01J49/26
CPC分类号： H01J49/0031 , H01J49/004
摘要： A mass spectrometry system is mounted with (1) an action planning module for determining a measurement schedule provided by a combination of an MS analysis and an MSn analysis (where n≧2) according to a measuring time provided previously; and (2) a mass spectrometry unit having a tandem mass spectrometry function for outputting a mass spectrum obtained by performing each measurement action constructing the measurement schedule.
摘要翻译：一种质谱系统安装有（1）动作计划模块，用于根据先前提供的测量时间确定由MS分析和MSn分析（其中n≥2）的组合提供的测量计划; 和（2）具有串联质谱分析功能的质谱分析装置，用于输出通过进行构成测定时间表的每个测定动作而得到的质谱。

47. 发明申请

US20110093214A1 DANGEROUS SUBSTANCE DETECTION SYSTEM 有权
标题翻译：危险物质检测系统
公开(公告)号：US20110093214A1
公开(公告)日：2011-04-21
申请号：US12903263
申请日：2010-10-13
申请人： Hisashi NAGANO , Yasuaki Takada , Minoru Sakairi , Yuichiro Hashimoto , Masuyuki Sugiyama
发明人： Hisashi NAGANO , Yasuaki Takada , Minoru Sakairi , Yuichiro Hashimoto , Masuyuki Sugiyama
IPC分类号： G01N33/22 , H01J49/26
CPC分类号： H01J49/0036 , G01N33/227 , H01J49/004
摘要： A method of quickly detecting a handmade explosive in a bottle with a low erroneous alarm frequency is provided. A sample gas generated from a bottle placed on a bottle placement space is sucked-in, and ions of the sample gas are generated by an ion source and subjected to mass analysis. The presence/absence of a mass spectrum derived from the handmade explosive is determined from an obtained mass spectrum, and the result thereof is displayed on a monitor, thereby quickly detecting the handmade explosive in the bottle or the handmade explosive adhering to the surface of the bottle at a low erroneous alarm frequency.
摘要翻译：提供了一种在低错误报警频率的瓶子中快速检测手工炸药的方法。将从放置在瓶放置空间的瓶子产生的样品气体吸入，并且通过离子源产生样品气体的离子并进行质量分析。从所获得的质谱确定来自手工炸药的质谱的存在/不存在，并将其结果显示在监视器上，从而快速检测瓶中的手工炸药或附着在表面上的手工炸药瓶子在低错误报警频率。

48. 发明申请

US20130032711A1 Mass Spectrometer 审中-公开
标题翻译：质谱仪
公开(公告)号：US20130032711A1
公开(公告)日：2013-02-07
申请号：US13565286
申请日：2012-08-02
申请人： Koji ISHIGURO , Masuyoshi Yamada , Hidetoshi Morokuma , Masuyuki Sugiyama , Yuichiro Hashimoto
发明人： Koji ISHIGURO , Masuyoshi Yamada , Hidetoshi Morokuma , Masuyuki Sugiyama , Yuichiro Hashimoto
IPC分类号： H01J49/26
CPC分类号： H01J49/0013
摘要： A unit which calculates a diameter of a throttle part of a valve and a diameter of an orifice from changes of vacuum degrees measured by vacuum gauges disposed in an ion source and a vacuum chamber having a mass analysis part in order to maintain a flow rate of reagent gas flowing in the ion source to be always fixed and changes vacuum degree in a reagent introduction part, the ion source or the vacuum chamber in order to correct difference from standard value is provided. A unit which measures discharge voltage, discharge current and plasma luminous intensity to grasp current situation in order to maintain plasma generation state in the ion source to be fixed and changes discharge condition such as discharge voltage in order to correct change part from standard value is provided.
摘要翻译：根据设置在离子源中的真空计测量的真空度的变化和具有质量分析部的真空室，计算阀的节流部分的直径和孔的直径的单元，以便保持流量提供了在离子源中流动的反应气体总是固定的，并且改变了试剂导入部分，离子源或真空室中的真空度，以便校正与标准值的差异。提供测量放电电压，放电电流和等离子体发光强度的单元，以掌握当前情况，以便保持离子源中的等离子体产生状态被固定，并且改变放电电压等放电条件以便将变化部分与标准值进行校正。

49. 发明申请

US20090020695A1 MASS SPECTROMETER 有权
标题翻译：质谱仪
公开(公告)号：US20090020695A1
公开(公告)日：2009-01-22
申请号：US12173328
申请日：2008-07-15
申请人： Hiroyuki Satake , Yuichiro Hashimoto , Yasuaki Takada
发明人： Hiroyuki Satake , Yuichiro Hashimoto , Yasuaki Takada
IPC分类号： B01D59/44
CPC分类号： H01J49/004 , H01J49/422 , H01J49/4255 , H01J49/427
摘要： A mass spectrometer includes a linear multipole electrode, an auxiliary electrode that applies a DC potential on the center axis of the linear multipole electrode, and a DC power supply that supplies a DC power to the auxiliary electrode. The DC potential slope formed on the center axis of the multipole electrode is changed according to the measuring condition. The ejection time of ions can be adjusted optimally by adjusting the potential slope so as to satisfy the measuring condition. If the ejection time of ions is shortened, confusion of different ion information items that might otherwise occur on a spectrum can be avoided. If the ejection time of ions is lengthened, detection limit exceeding can be avoided and ions can be measured efficiently, thereby highly efficient ion measurements are always assured.
摘要翻译：质谱仪包括线性多极电极，在线性多极电极的中心轴上施加直流电位的辅助电极和向辅助电极提供直流电力的直流电源。根据测量条件改变在多极电极的中心轴上形成的直流电位斜率。通过调整电位斜率以满足测量条件，可以最佳地调节离子的喷射时间。如果离子的喷射时间缩短，则可以避免在光谱上可能发生的不同离子信息项的混淆。如果离子的喷射时间延长，则可以避免超过检测极限，有效测量离子，从而确保高效的离子测量。

50. 发明授权

US08044349B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US08044349B2
公开(公告)日：2011-10-25
申请号：US12173328
申请日：2008-07-15
申请人： Hiroyuki Satake , Yuichiro Hashimoto , Yasuaki Takada
发明人： Hiroyuki Satake , Yuichiro Hashimoto , Yasuaki Takada
IPC分类号： H01J49/00
CPC分类号： H01J49/004 , H01J49/422 , H01J49/4255 , H01J49/427
摘要： A mass spectrometer includes a linear multipole electrode, an auxiliary electrode that applies a DC potential on the center axis of the linear multipole electrode, and a DC power supply that supplies a DC power to the auxiliary electrode. The DC potential slope formed on the center axis of the multipole electrode is changed according to the measuring condition. The ejection time of ions can be adjusted optimally by adjusting the potential slope so as to satisfy the measuring condition. If the ejection time of ions is shortened, confusion of different ion information items that might otherwise occur on a spectrum can be avoided. If the ejection time of ions is lengthened, detection limit exceeding can be avoided and ions can be measured efficiently, thereby highly efficient ion measurements are always assured.
摘要翻译：质谱仪包括线性多极电极，在线性多极电极的中心轴上施加直流电位的辅助电极和向辅助电极提供直流电力的直流电源。根据测量条件改变在多极电极的中心轴上形成的直流电位斜率。通过调整电位斜率以满足测量条件，可以最佳地调节离子的喷射时间。如果离子的喷射时间缩短，则可以避免在光谱上可能发生的不同离子信息项的混淆。如果离子的喷射时间延长，则可以避免超过检测极限，有效测量离子，从而确保高效的离子测量。

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