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    • 41. 发明申请
    • Quinoline Derivatives and Their Use as Pesticides
    • 喹啉衍生物及其作为农药的用途
    • US20090029855A1
    • 2009-01-29
    • US12282608
    • 2007-03-12
    • Michael PuhlWassilios GrammenosJoachim RheinheimerJan Klaas LohmannMichael RackLiliana Parra RapadoChristopher KoradinJurgen LangewaldDeborah L. CulbertsonDouglas D. AnspaughHassan Oloumi-SadeghiHenry Van Tuyl CotterDavid G. Kuhn
    • Michael PuhlWassilios GrammenosJoachim RheinheimerJan Klaas LohmannMichael RackLiliana Parra RapadoChristopher KoradinJurgen LangewaldDeborah L. CulbertsonDouglas D. AnspaughHassan Oloumi-SadeghiHenry Van Tuyl CotterDavid G. Kuhn
    • A01N25/26C07D215/14A01N43/42A01N59/26A01P5/00A01P7/04
    • C07D215/12C07D215/60
    • This invention relates to quinoline derivatives of formula I wherein R1, R2, R3 are each independently halogen, hydroxy, cyano, amino, nitro, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C7-cycloalkyl, C3-C7-cycloalkyl-C1-C4-alkyl, C1-C6-alkoxy, C2-C6-alkenyloxy, C2-C6-alkynyloxy, C1-C4-alkoxy-C1-C4-alkoxy, C3-C7-cycloalkyl-C1-C4-alkoxy, C(OH)(CF3)2, C1-C6-haloalkyl, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-haloalkylthio, C1-C6-alkylsulfinyl, C1-C6-haloalkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylsulfonyl, C(Ra)═O, C(Ra)═NORb, C(═O)ORx, or C(═O)NRxRy; Ra is hydrogen or C1-C4-alkyl; Rb is hydrogen, C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkynyl, C1-C4-haloalkyl, or C2-C4-haloalkenyl; Rx, Ry are each independently hydrogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy-C1-C4-alkyl, C1-C4-thioalkyl-C1-C4-alkyl, C1-C4-alkyl-S(═O)C1-C4-alkyl, C1-C4-alkyl-S(═O)2C1-C4-alkyl, C3-C6-cyloalkyl, C1-C4-alkyl-C3-C6-cycloalkyl, C3-C6-alkenyl, C3-C6-alkinyl; R4, R5, R6, R7 are each independently hydrogen, halogen, cyano, amino, nitro, hydroxy, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-haloalkyl, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-haloalkylthio, C1-C6-alkylsulfinyl, C1-C6-haloalkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylsulfonyl, or C(═O)ORc; Rc is hydrogen, C1-C6-alkyl, C2-C6-alkenyl, or C2-C6-alkinyl; m and n are each independently 1, 2, 3, 4, or 5; p is 0, 1, 2, 3, 4, or 5; and the N-oxides, enantiomers, diastereomers and salts thereof, processes and intermediates for the preparation of compounds I, use of compounds I for combating insects, acarids, or nematodes and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites using compounds I.
    • 本发明涉及式I的喹啉衍生物,其中R 1,R 2,R 3各自独立地为卤素,羟基,氰基,氨基,硝基,C 1 -C 6烷基,C 2 -C 6 - 烯基,C 2 -C 6炔基,C 3 -C 7 - 环烷基,C 3 -C 7 - 环烷基-C 1 -C 4 - 烷基,C 1 -C 6 - 烷氧基,C 2 -C 6 - 烯氧基,C 2 -C 6 - 炔氧基,C 1 -C 4烷氧基-C 1 -C 4烷氧基,C 3 -C 7 - 环烷基 - C 1 -C 6烷氧基,C(OH)(CF 3)2,C 1 -C 6卤代烷基,C 1 -C 6卤代烷氧基,C 1 -C 6烷硫基,C 1 -C 6卤代烷硫基,C 1 -C 6烷基亚磺酰基, C 1 -C 6烷基磺酰基,C 1 -C 6卤代烷基磺酰基,C(R a)-O,C(R a)-NOR b,C(-O)OR x或C(-O)NR x R y; R a是氢或C 1 -C 4 - 烷基; R b是氢,C 1 -C 4 - 烷基,C 2 -C 4 - 烯基,C 2 -C 4 - 炔基,C 1 -C 4卤代烷基或C 2 -C 4 - 卤代烯基; R x,R y各自独立地为氢,C 1 -C 4 - 烷基,C 1 -C 4 - 卤代烷基,C 1 -C 4 - 烷氧基-C 1 -C 4烷基,C 1 -C 4 - 硫代烷基-C 1 -C 4烷基,C 1 -C 4烷基 - S(-O)C 1 -C 4 - 烷基,C 1 -C 4烷基-S(-O)2 C 1 -C 4烷基,C 3 -C 6 - 环烷基,C 1 -C 4烷基-C 3 -C 6环烷基,C 3 -C 6 - 烯基,C 3 -C 6 - 炔基; R4,R5,R6,R7各自独立地为氢,卤素,氰基,氨基,硝基,羟基,C1-C6-烷基,C1-C6-烷氧基,C1-C6-卤代烷基,C1-C6-卤代烷氧基,C1-C6- C 1 -C 6烷基亚磺酰基,C 1 -C 6烷基磺酰基,C 1 -C 6卤代烷基磺酰基或C(-O)OR c; R c是氢,C 1 -C 6 - 烷基,C 2 -C 6 - 烯基或C 2 -C 6 - 炔基; m和n各自独立地为1,2,3,4或5; p是0,1,2,3,4或5; 及其N-氧化物,对映异构体,非对映异构体及其盐,制备化合物I的方法和中间体,化合物I用于防治昆虫,螨虫或线虫的用途,以及用于治疗,控制,预防或保护动物免受感染或 使用化合物I的寄生虫感染
    • 44. 发明授权
    • Fungicidal mixtures
    • 杀菌混合物
    • US06699874B2
    • 2004-03-02
    • US10314594
    • 2002-12-10
    • Henry Van Tuyl CotterLeslie MayGunter ReichertEwald Sieverding
    • Henry Van Tuyl CotterLeslie MayGunter ReichertEwald Sieverding
    • A01N4354
    • A01N43/90A01N2300/00
    • Fungicidal compositions comprising an acceptable carrier and/or surface active agent and synergistically effective amounts of (a) at least one azolopyrimidine of formula I  in which R1, R2, L1, L2 and L3 have the meaning given in claim 1; and (b) at least one fungicidal active ingredient selected from benomyl, carboxin, captan, chlorothalonil, copper oxychloride, cyprodinil, dimethomorph, dithianon, dodine, famoxadone, fenhexamid, fenpiclonil, fenpropimorph, fluazinam, mancozeb, metalaxyl, pyrimethanil, quinoxifen, sulfur, triforine, vinclozolin, a fungicidal triazole derivative, and a synthetic strobilurine derivative. The invention also provides a method of controlling the growth of phytopathogenic fungi at a locus by applying synergistically effective amounts of at least one azolopyrimidine of formula I and at least one fungicidal active ingredient (b) to the locus.
    • 包含可接受的载体和/或表面活性剂和协同有效量的(a)至少一种R 1,R 2,L 1,L 2和L 3的式Iin的偶氮嘧啶的杀真菌组合物 >具有权利要求1中给出的含义; 和(b)至少一种杀真菌活性成分,其选自苯菌灵,呋喃丹,克拉曼,百菌清,氯氧化铜,西酞替尼,烯酰吗啉,二噻吩,十二烷,恶唑酮,芬己酰,芬替尼,芬卡芬,氟啶胺,代森锰锌,甲霜灵,嘧霉胺,喹喔啉, ,triperine,长春菌素,杀真菌三唑衍生物和合成次溴酸衍生物。 本发明还提供了一种通过将协同有效量的至少一种式I的偶氮嘧啶和至少一种杀真菌活性成分(b)施用于该基因座来控制植物病原真菌在一个场所生长的方法。
    • 46. 发明授权
    • Fungicidal mixtures
    • US06346535B1
    • 2002-02-12
    • US09240412
    • 1999-01-29
    • Henry Van Tuyl CotterGunther ReichertEwald SieverdingPetrus Martinus Franciscus Emanuel Jegerings
    • Henry Van Tuyl CotterGunther ReichertEwald SieverdingPetrus Martinus Franciscus Emanuel Jegerings
    • A01N4354
    • A01N35/04A01N59/20A01N59/02A01N55/00A01N47/44A01N47/38A01N47/14A01N47/04A01N43/90A01N43/84A01N43/82A01N43/76A01N43/653A01N43/60A01N43/56A01N43/54A01N43/40A01N43/42A01N43/36A01N43/32A01N43/30A01N37/50A01N37/46A01N37/38A01N37/34A01N37/06A01N2300/00
    • The invention relates to a novel fungicidal composition comprising synergistically effective amounts of at least one benzophenone of formula I wherein R1 represents a halogen atom, an optionally substituted alkyl, alkanoyloxy or alkoxy group; or a hydroxy group, R2 represents a halogen atom or an optionally substituted alkyl group, R3 independently represents a halogen atom, an optionally substituted alkyl or alkoxy group or a nitro group; m is 0 or an integer of 1 to 3; R4 represents a halogen atom, a cyano, carboxy, hydroxy or nitro group or an optionally substituted alkyl, alkoxy, alkenyl, alkylthio, alkylsulphinyl, alkylsulphonyl or amino group; R5 represents an optionally substituted alkyl group; R6 represents a halogen atom or a nitro group, an optionally substituted alkyl, alkoxy, alkenyloxy, alkynyloxy, alkylthio, cycloalkyl, cycloalkyloxy, aryloxy group; R7 independently represents a halogen atom, an optionally substituted alkyl, alkenyl, alkynyl, alkoxy, alkenyloxy, alkynyloxy, cycloalkyl, cycloalkoxy group; n is 0 or 1; and at least one fungicidally active ingredient selected from the groups consisting of (A), (B), (C), (D) and (E) wherein: (A) is an ergosterol biosynthesis inhibitor; (B) is a strobilurine derivative, (C) is a melanin biosynthesis inhibitor; (D) is a compound selected from the group consisting of acibenzolar, benomyl, captan, carboxin, chlorothalonil, copper, cyprodinil, dinocap, dithianon, dimethomorph, dodine, ethirimol, famoxadone, fenpiclonil, fluazinam, mancozeb, metalaxyl, pyrifenox, sulfur, vinclozolin and (E) is an azolopyrimidine of formula II  iwherein R8 and R9 each independently represent hydrogen or an optionally substituted alkyl, alkenyl, alkynyl, alkadienyl, aryl, heteroaryl, cycloalkyl, bicycloalkyl or heterocyclyl group, or R8 and R9 together with the interjacent nitrogen atom represent an optionally substituted heterocyclic ring, R10 represents hydrogen or an alkyl or aryl group, R11 represents a hydrogen or halogen atom or an alkyl or alkoxy group, L independently represents a halogen atom or an optionally substituted alkyl or alkoxy group, p is 0 or an integer from 1 to 5; and A represents N or CR2, wherein R12 has the meaning given for R10; together with a fungicidally acceptable carrier and/or surface active agent, and to a method of controlling the growth of phytopathogenic fungi which comprises applying synergistically effective amounts of the composition to the locus.
    • 48. 发明授权
    • Fungicidal mixtures
    • 杀菌混合物
    • US6090806A
    • 2000-07-18
    • US143806
    • 1998-08-31
    • Henry Van Tuyl Cotter
    • Henry Van Tuyl Cotter
    • A01N43/76A01N31/535
    • A01N43/76
    • The invention relates to fungicidal compositions comprising synergistically effective amounts ofat least one acrylic acid morpholide of formula I ##STR1## in which R.sup.1 and R.sup.2 have the meaning given in claim 1 and at least one fungicidal oxazolidinone of formula II ##STR2## in which R.sup.3.sub.1 R.sup.4 and Ar have the meaning given in claim 1, and to a method of controlling the growth of phythopathogenic fungi and/or the plant disease caused by them at a locus which comprises applying synergistically effective amounts of at least one acrylic acid morpholide of formula I (a) and at least one fungicidal compound of formula II (b) to the locus, together with a fungicidally acceptable carrier and/or surface active agent.
    • 本发明涉及杀真菌组合物,其包含协同有效量的式I的至少一种丙烯酸吗啉,其中R 1和R 2具有权利要求1中给出的含义,和至少一种式II的杀真菌恶唑烷酮,其中R 31 R 4和Ar具有 权利要求1的方法,以及一种控制由它们引起的植物病原真菌和/或植物疾病生长的方法,所述方法包括将协同有效量的至少一种式I(a)的丙烯酸吗啉代和至少一种杀真菌剂 式II(b)的化合物与杀真菌剂可接受的载体和/或表面活性剂。