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41. 发明授权

US07597900B2 Tissue abrasives 有权
标题翻译：组织磨料
公开(公告)号：US07597900B2
公开(公告)日：2009-10-06
申请号：US10696878
申请日：2003-10-30
申请人： Jose Zimmer , Sean Lee , Coni Rosati
发明人： Jose Zimmer , Sean Lee , Coni Rosati
IPC分类号： A61K8/02
CPC分类号： A61Q11/00 , A61K8/22 , A61K8/25 , A61K2800/28 , A61Q1/02 , A61Q1/06 , A61Q3/00 , A61Q5/02 , A61Q9/02 , A61Q15/00 , A61Q17/00 , A61Q17/005 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A61Q19/10 , C03C3/062 , C03C3/078 , C03C3/087 , C03C3/089 , C03C3/091 , C03C3/093 , C03C3/097 , C03C3/112 , C03C3/115 , C03C3/16 , C03C3/17 , C03C4/0007 , C03C10/00 , C03C12/00 , C03C14/004 , C03C17/30 , C03C21/005 , C03C2204/02
摘要： Abrasive compositions which include bioactive materials, such as bioactive glass and bioactive ceramics, which provide biological properties such as anti-inflammatory, anti-microbial, anti-oxidant effects, improved wound healing, and/or other beneficial effects are provided. Also provided are abrasive compositions comprising relatively non-toxic, bioinert glasses and ceramics which provide good abrasive effects, reduce or eliminate potentially harmful small particles; reduce or eliminate clogging of dermabrasion equipment; possess a relatively large surface area for applying coatings; and may be inexpensive and simple to make. Methods for abrading human or animal tissue, such as human skin, by contacting such tissue with these abrasive compositions is also provided.
摘要翻译：提供了包括生物活性材料（例如生物活性玻璃和生物活性陶瓷）的研磨组合物，其提供生物学特性如抗炎，抗微生物，抗氧化作用，改善的伤口愈合和/或其他有益效果。还提供了包含相对无毒的生物惰性玻璃和陶瓷的磨料组合物，其提供良好的研磨效果，减少或消除潜在有害的小颗粒; 减少或消除皮肤磨损设备的堵塞; 具有较大的表面积用于涂覆; 并且可能是廉价和简单的。还提供了通过使这些组织与这些磨料组合物接触来研磨人或动物组织如人皮肤的方法。

42. 发明申请

US20070275021A1 NEW COSMETIC, PERSONAL CARE, CLEANING AGENT, AND NUTRITIONAL SUPPLEMENT COMPOSITIONS AND METHODS OF MAKING AND USING SAME 有权
标题翻译：新化妆品，个人护理，清洁剂和营养补充剂组合物及其制备和使用方法
公开(公告)号：US20070275021A1
公开(公告)日：2007-11-29
申请号：US11775615
申请日：2007-07-10
申请人： Sean Lee , Susanna Kessler , Oliver Forberich , Claire Buchwar , David Greenspan
发明人： Sean Lee , Susanna Kessler , Oliver Forberich , Claire Buchwar , David Greenspan
IPC分类号： A61K33/00 , A61K8/25 , A61Q17/04
CPC分类号： A61Q19/08 , A61K8/22 , A61K8/25 , A61Q1/02 , A61Q1/06 , A61Q3/00 , A61Q5/02 , A61Q9/02 , A61Q11/00 , A61Q15/00 , A61Q17/005 , A61Q17/04 , A61Q19/00 , A61Q19/10 , C03C3/097 , C03C3/112 , C03C3/115 , C03C4/0007 , C03C4/0021 , C03C4/0035 , C03C12/00 , C03C2204/02
摘要： The present invention involves new cosmetic, personal care, cleaning agent, biocidal agent, functional food, and nutritional supplement compositions. These new compositions incorporate bioactive glass into cosmetics, personal care items, cleaning agents, biocidal agents, functional foods, and nutritional supplements. The present invention also involves methods of making and methods of using such compositions.
摘要翻译：本发明涉及新的化妆品，个人护理，清洁剂，杀生物剂，功能性食品和营养补充剂组合物。这些新组合物将生物活性玻璃引入化妆品，个人护理用品，清洁剂，杀生物剂，功能食品和营养补充剂中。本发明还涉及制备方法和使用这些组合物的方法。

43. 发明授权

US07271403B2 Isolating phase change memory devices 有权
标题翻译：隔离相变存储器件
公开(公告)号：US07271403B2
公开(公告)日：2007-09-18
申请号：US10319183
申请日：2002-12-13
申请人： Ilya Karpov , Ward Parkinson , Sean Lee
发明人： Ilya Karpov , Ward Parkinson , Sean Lee
IPC分类号： H01L47/00
CPC分类号： H01L27/2409 , H01L45/06
摘要： A phase change memory may be made using an isolation diode in the form of a Schottky diode between a memory cell and a word line. The use of Schottky diode isolation devices may make the memory more scaleable in some embodiments.
摘要翻译：可以使用在存储器单元和字线之间的肖特基二极管形式的隔离二极管来进行相变存储器。在一些实施例中，使用肖特基二极管隔离装置可使存储器更可扩展。

44. 发明申请

US20070149218A1 Method and apparatus for conveying regions for controlling a mobile device based upon location 审中-公开
标题翻译：用于基于位置传送用于控制移动设备的区域的方法和装置
公开(公告)号：US20070149218A1
公开(公告)日：2007-06-28
申请号：US11443787
申请日：2006-05-31
申请人： Sean Lee
发明人： Sean Lee
IPC分类号： H04Q7/20
CPC分类号： G01S19/14
摘要： A mobile wireless system (10) includes a transmitter such as a satellite (18) that broadcasts wireless signals such as boundaries for specific areas to a mobile receiving device (22). Mobile receiving device (22) may include an antenna (26) and a mobile receiving device (28). A locating receiver (50) is used to generate locating signals so that a determination may be made to the location of the mobile receiving device. In response to comparing the location and the boundaries, various behaviors of the receiving device can be controlled. Behaviors can include display or blockage of audio, video or data channels or other information may be used by the mobile receiving device.
摘要翻译：移动无线系统（10）包括诸如卫星（18）的发射机，其向移动接收设备（22）广播诸如特定区域的边界的无线信号。移动接收设备（22）可以包括天线（26）和移动接收设备（28）。定位接收机（50）用于产生定位信号，从而可以确定移动接收设备的位置。响应于比较位置和边界，可以控制接收设备的各种行为。行为可以包括音频，视频或数据信道的显示或阻塞，或者可由移动接收设备使用其他信息。

45. 发明授权

US06756060B1 Anti-inflammatory and antimicrobial uses for bioactive glass compositions 有权
标题翻译：用于生物活性玻璃组合物的抗炎和抗微生物用途
公开(公告)号：US06756060B1
公开(公告)日：2004-06-29
申请号：US09560046
申请日：2000-04-27
申请人： David C. Greenspan , Jon K. West , Sean Lee , James L. Meyers , Mason Diamond
发明人： David C. Greenspan , Jon K. West , Sean Lee , James L. Meyers , Mason Diamond
IPC分类号： A61K914
CPC分类号： A61Q1/02 , A61K8/25 , A61K45/06 , A61L15/18 , A61L15/44 , A61L15/46 , A61Q5/00 , A61Q17/005 , A61Q19/00 , C03C4/0007 , Y10S424/13 , Y10S514/829 , Y10S514/83 , Y10S514/831 , Y10S514/859 , Y10S514/861 , Y10S514/862 , Y10S514/863 , Y10S514/864 , Y10S514/886 , Y10S514/887 , Y10S514/951 , Y10S514/965
摘要： Compositions and methods for treating wounds to significantly reduce the healing time, reduce the incidence of scar formation, improve the success of skin grafts, reduce the inflammatory response and providing anti-bacterial treatments to a patient in need thereof, that include small non-interlinked particles of bioactive glass or highly porous bioactive glass, are disclosed. Anti-bacterial solutions derived from bioactive glass, and methods of preparation and use thereof, are also disclosed. The compositions include non-interlinked particles of bioactive glass, alone or in combination with anti-bacterial agents and/or anti-inflammatory agents. The compositions can include an appropriate carrier for topical administration. Anti-bacterial properties can be imparted to implanted materials, such as prosthetic implants, sutures, stents, screws, plates, tubes, and the like, by incorporating small bioactive glass particles or porous bioactive glass into or onto the implanted materials. Anti-bacterial properties can also be imparted to devices used for in vitro and ex vivo cell culture by incorporating non-interlinked particles of bioactive glass into the devices. Anti-bacterial compositions derived from aqueous extracts of bioactive glass are also disclosed. These compositions can be used, for example, in food preparation, solutions used for cell culture, and buffer solutions, such as i.v. solutions.
摘要翻译：用于治疗创伤以显着减少愈合时间的组合物和方法，减少瘢痕形成的发生率，改善皮肤移植物的成功，减少炎症反应并向有需要的患者提供抗菌治疗，包括小的非相互连接公开了生物活性玻璃或高度多孔生物活性玻璃的颗粒。还公开了衍生自生物活性玻璃的抗菌溶液及其制备和使用方法。组合物包括单独的或与抗细菌剂和/或抗炎剂组合的生物活性玻璃的非互连颗粒。组合物可以包括用于局部给药的合适的载体。通过将小生物活性玻璃颗粒或多孔生物活性玻璃并入到植入的材料中，可将植物材料（例如假体植入物，缝合线，支架，螺钉，板，管等）赋予抗菌性能。通过将非生物活性玻璃的非互连颗粒结合到装置中，也可以将抗细菌性质赋予用于体外和离体细胞培养的装置。还公开了衍生自生物活性玻璃的水提取物的抗菌组合物。这些组合物可用于例如食品制备，用于细胞培养的溶液和缓冲溶液，例如静脉内。解决方案

46. 发明授权

US06177248B1 Downstream genes of tumor suppressor WT1 失效
标题翻译：肿瘤抑制因子WT1的下游基因
公开(公告)号：US06177248B1
公开(公告)日：2001-01-23
申请号：US09256301
申请日：1999-02-24
申请人： Jonathan Oliner , Vivi Truong , Daniel Haber , Sean Lee
发明人： Jonathan Oliner , Vivi Truong , Daniel Haber , Sean Lee
IPC分类号： C12Q168
CPC分类号： C12Q1/6827 , C12Q2600/158 , Y02A90/26
摘要： Methods are provided for diagnosing cancers, drug-screening, and functionally analyzing mutations involving the WT1 gene. The methods involve use of the newly identified set of genes which are regulated by WT1 as well as by the set of genes which are regulated by WT1 fusions to EWS. Monitoring expression levels of these sets of genes can be used as an indicator of the genetic status of the gene. It can also identify which have similar effects on down-stream genes.
摘要翻译：提供了诊断癌症，药物筛选和功能分析涉及WT1基因的突变的方法。这些方法涉及使用由WT1调节的新鉴定的一组基因以及由WT1融合到EWS调节的一组基因。监测这些基因组的表达水平可用作基因遗传状态的指标。它还可以确定哪些对下游基因具有相似的影响。

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