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41. 发明申请

US20080006554A1 Packaging assembly for a catheter 审中-公开
标题翻译：导管包装组件
公开(公告)号：US20080006554A1
公开(公告)日：2008-01-10
申请号：US11483325
申请日：2006-07-07
申请人： Niall Duffy , Thomas Farrell , James Smedley , Kevin Treacy
发明人： Niall Duffy , Thomas Farrell , James Smedley , Kevin Treacy
IPC分类号： A61B19/02
CPC分类号： A61M25/002
摘要： An assembly for packaging a catheter includes flexible tubing capable of being coiled, and tubular retainer having a passageway extending therethrough. The tubular retainer includes a distal section for coupling to a proximal end of the tubing. A proximal end of the tubular retainer includes an opening for receiving a luer of the catheter assembly. A keyway is provided at a proximal end of the tubular retainer, the keyway being adapted to receive an inflation port of the luer. The keyway may include a snap point at a proximal end thereof, wherein the snap point is dimensioned such that a force is required to pass the inflation port past the snap point, thereby resulting in a snap fit. The keyway may include an entry portion beginning at the proximal end of the tubular retainer, and a nose portion disposed distal of the entry portion, with a snap point disposed therebetween. Depending on the length of the entry portion, a portion of the luer may be protected by the tubular retainer. The snap point provides a snap fit for the luer within the tubular retainer.
摘要翻译：用于包装导管的组件包括能够卷绕的柔性管，以及具有延伸穿过其中的通道的管状保持器。管状保持器包括用于联接到管道的近端的远端部分。管状保持器的近端包括用于接收导管组件的路厄尔的开口。键管设置在管状保持器的近端处，键槽适于容纳路厄尔的充气口。键槽可以包括在其近端处的卡扣点，其中卡扣点的尺寸被设计成使得需要力以使充气端口通过卡扣点，从而导致卡扣配合。键槽可以包括从管状保持器的近端开始的入口部分和设置在入口部分的远侧的鼻部，其间设置有卡扣点。取决于入口部分的长度，路厄尔的一部分可以被管状保持器保护。卡扣点为管状保持器内的鲁尔提供卡扣配合。

42. 发明授权

US06730116B1 Medical device for intraluminal endovascular stenting 有权
标题翻译：用于管腔内血管内支架术的医疗装置
公开(公告)号：US06730116B1
公开(公告)日：2004-05-04
申请号：US09292991
申请日：1999-04-16
申请人： Lone Wolinsky , Amir David Loshakove , Arvi Penner , Offer Nativ , Gil Naor , Niall Duffy
发明人： Lone Wolinsky , Amir David Loshakove , Arvi Penner , Offer Nativ , Gil Naor , Niall Duffy
IPC分类号： A61F206
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91525 , A61F2002/91533 , A61F2002/91583 , A61F2230/0054 , A61F2250/0098
摘要： A medical device includes a catheter and a stent mounted on the catheter, the stent having a hollow, cylindrical body made with a plurality of rings. The rings each extend circumferentially around the cylindrical body and include an undulating series of peaks and valleys. The rings are joined together by a series of links which are shaped and arranged to promote longitudinal flexibility as the stent is delivered on the catheter and effective scaffolding after deployment. In one aspect of the invention, the rings are provided with inflection points on some portions of the rings which extend in a generally circumferential direction for a short distance. A link is joined at one end at the inflection point on one ring and also joined at a second end at a second inflection point on an adjacent ring. This construction allows the crimped stent to flex longitudinally when it is subjected to bending forces such as those encountered during delivery of the stent and catheter through a tortuous coronary artery.
摘要翻译：医疗装置包括导管和安装在导管上的支架，支架具有由多个环制成的中空的圆筒体。这些环各自围绕圆柱体圆周延伸并且包括起伏的一系列峰和谷。这些环通过一系列连接件连接在一起，这些连接件成形和布置成当支架在导管上被输送并且在部署之后有效的脚手架时促进纵向柔性。在本发明的一个方面中，环在环的某些部分上设置有拐点，所述拐点在大致圆周方向上延伸短距离。连杆在一个环的拐点的一端连接，并且在相邻环上的第二拐点处的第二端处连接。这种结构允许卷曲的支架在受到弯曲力时纵向弯曲，例如在通过曲折冠状动脉输送支架和导管期间遇到的弯曲力。

43. 发明授权

US06191072B1 Herbicidal cutting line 失效
标题翻译：除草切割线
公开(公告)号：US06191072B1
公开(公告)日：2001-02-20
申请号：US09217881
申请日：1998-12-21
申请人： Niall Duffy
发明人： Niall Duffy
IPC分类号： A01N2534
CPC分类号： A01D43/14 , A01D34/4168 , A01M21/043 , A01N25/34 , Y10T428/2938 , Y10T428/2971
摘要： A cutting line for a rotating-line trimmer that simultaneously applies herbicide as vegetation is cut. The herbicidal cutting line comprises a flexible cutting-line core (13) herbicidal coating (15) that covers all or part of the line core and a thin protective shield (17) covering all or part of the herbicidal coating. As vegetation is cut, protective shield (17) ruptures exposing herbicidal coating (15) to vegetation. The cutting line is used with existing line trimmers in applications in which vegetation regrowth is objectionable.
摘要翻译：切割用于同时施用除草剂作为植被的旋转线修剪机的切割线。除草切割线包括覆盖全部或部分线芯的柔性切割线芯（13）除草涂层（15）和覆盖全部或部分除草涂层的薄保护屏蔽（17）。当植被被切割时，防护罩（17）将除草剂（15）暴露于植被。切割线与现有的线切割机一起使用在植被再生长令人反感的应用中。

44. 发明授权

US09452047B2 Heart valve prosthesis recapture devices 有权
标题翻译：心脏瓣膜假体回收装置
公开(公告)号：US09452047B2
公开(公告)日：2016-09-27
申请号：US13440372
申请日：2012-04-05
申请人： Niall Duffy
发明人： Niall Duffy
IPC分类号： A61F2/24 , A61F2/95
CPC分类号： A61F2/2436 , A61F2/958 , A61F2002/9528 , A61F2002/9534 , A61F2250/0018 , A61F2250/0036 , A61F2250/0039
摘要： Heart valve prosthesis recapture devices and methods for recapture are disclosed, which can be used for recapturing a partially deployed heart valve prosthesis. The recapture device comprises a recapture sleeve, configured to envelop and collapse a partially deployed heart valve prosthesis. The recapture sleeve comprises a distal end, configured to be securely attached to a guide wire, and a proximal end, comprising an opening along a longitudinal axis of the recapture sleeve. The opening can be configured to expand as it engages the heart valve prosthesis, and be biased toward a closed configuration. An attachment element can interface with the distal end of the recapture sleeve and be securely attached to a guide wire, such as by crimping. The recapture sleeve can include a support structure comprising at least one spine and a plurality of ribs.
摘要翻译：公开了用于重新捕获的心脏瓣膜假体再捕获装置和方法，其可用于重新部分部署的心脏瓣膜假体。再捕获装置包括重新套管套筒，其构造成包封并折叠部分展开的心脏瓣膜假体。重新取回套筒包括构造成牢固地附接到导丝的远端，以及近端，包括沿着重新捕获套筒的纵向轴线的开口。开口可被构造成在其与心脏瓣膜假体接合时膨胀，并且被朝向闭合构型偏置。附接元件可以与再捕获套筒的远端相接触，并且例如通过卷曲牢固地附接到导丝。再捕获套筒可以包括包括至少一个脊和多个肋的支撑结构。

45. 发明申请

US20140031922A1 Delivery Catheter With Distal Moving Capsule for Transapical Prosthetic Heart Valve Delivery 有权
标题翻译：输送导管与远端假性心脏瓣膜输送的远端移动胶囊
公开(公告)号：US20140031922A1
公开(公告)日：2014-01-30
申请号：US13557488
申请日：2012-07-25
申请人： Niall Duffy , Ronan Rogers , John Gallagher , Gavin Kenny
发明人： Niall Duffy , Ronan Rogers , John Gallagher , Gavin Kenny
IPC分类号： A61F2/24
CPC分类号： A61F2/966 , A61F2/2436 , A61F2002/9505 , A61F2002/9517 , A61F2002/9665
摘要： Heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly with a rotatable control knob and a catheter including an introducer shaft, an intermediate shaft extending from the handle assembly, an inner shaft extending from the handle assembly, and a capsule for containing a prosthesis. The distal end of the capsule can be connected to a distal end of the inner shaft, which can be moved in a distal direction by the rotatable control knob to deploy the prosthesis. By advancing the introducer through the deployed prosthesis and retracting the capsule to mate with the introducer, a smooth profile can be created for retraction of the system through the deployed prosthesis, minimizing hang-ups and snagging.
摘要翻译：公开了使用输送导管递送和植入心脏瓣膜的心脏瓣膜输送系统和方法。输送系统可以包括具有可旋转控制旋钮的手柄组件和包括导引器轴的导管，从手柄组件延伸的中间轴，从手柄组件延伸的内轴以及用于容纳假体的胶囊。胶囊的远端可以连接到内轴的远端，其可以通过可旋转的控制旋钮在远端方向上移动以展开假体。通过推进引导器穿过部署的假体并缩回胶囊以与导引器配合，可以创建平滑的轮廓，用于通过部署的假体缩回系统，最大限度地减少挂起和阻塞。

46. 发明授权

US08298279B2 Stent including a toggle lock strut 有权
标题翻译：支架包括一个切换锁支柱
公开(公告)号：US08298279B2
公开(公告)日：2012-10-30
申请号：US12566237
申请日：2009-09-24
申请人： Gerry Clarke , Niall Duffy , Francis John Harewood
发明人： Gerry Clarke , Niall Duffy , Francis John Harewood
IPC分类号： A61F2/06 , A61F2/82
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91591 , A61F2230/0054
摘要： A tubular stent includes cylindrical rings disposed adjacent to each other and coupled to each other by a plurality of longitudinal segments. Each cylindrical ring includes circumferentially oriented toggle lock struts. The toggle lock struts include a first arm and a second arm coupled together at an elbow. When the stent is in a compressed configuration for delivery, the toggle lock struts are bent at the elbow such that the first arm is disposed at an angle of less than 180 degrees relative to the second arm. Upon radial expansion of the stent, the toggle lock struts are unbent to a straight configuration and permitted to relax slightly beyond the straight configuration to a locked configuration such that the angle between the first arm and the second arm changes from less than 180 degrees to more than 180 degrees.
摘要翻译：管状支架包括彼此相邻布置并且通过多个纵向段彼此连接的圆柱形环。每个圆柱形环包括周向定向的拨动锁定支柱。肘节锁支撑件包括以肘部联接在一起的第一臂和第二臂。当支架处于用于输送的压缩构型中时，肘节锁定支柱在肘部弯曲，使得第一臂相对于第二臂设置成小于180度的角度。在支架的径向膨胀时，肘节锁定支柱不直接成直线构造，并允许稍微超过直线构型放松到锁定构型，使得第一臂和第二臂之间的角度从小于180度变化到更多超过180度。

47. 发明申请

US20120158129A1 SYSTEMS AND METHODS FOR POSITIONING A HEART VALVE USING VISUAL MARKERS 有权
标题翻译：使用可视标记定位心脏瓣膜的系统和方法
公开(公告)号：US20120158129A1
公开(公告)日：2012-06-21
申请号：US13325439
申请日：2011-12-14
申请人： Niall Duffy , Gerry McCaffrey , Noam Miller , Yossi Tuval , Daniel Glozman
发明人： Niall Duffy , Gerry McCaffrey , Noam Miller , Yossi Tuval , Daniel Glozman
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61F2/2436 , A61F2002/9505 , A61F2250/0032 , A61F2250/0097 , A61F2250/0098
摘要： A valve retainer is connected to an elongate delivery member. The valve retainer is configured to releasably secure a prosthesis (e.g., a heart valve prosthesis) to the delivery member during delivery to a target site in a body (e.g., a native valve annulus). The valve retainer includes a rotational identifier that identifies the rotational orientation of the valve retainer when the valve retainer is positioned proximate to the target site. A heart valve prosthesis can include a commissural post that has a predetermined rotational position relative to the rotational identifier, such that the heart valve prosthesis can be rotationally aligned with the native commissures of the native valve by rotating the delivery member and the valve retainer until the commissural post is aligned with a native valve commissure and the rotational identifier is visible.
摘要翻译：阀保持器连接到细长的传送构件。阀保持器被构造成在输送到身体（例如，天然瓣膜环）中的目标部位时将假体（例如，心脏瓣膜假体）可释放地固定到递送构件。阀保持器包括旋转标识符，当旋转标识符识别当阀保持器靠近目标位置定位时的阀保持器的旋转取向。心脏瓣膜假体可以包括相对于旋转标识符具有预定旋转位置的连合柱，使得心脏瓣膜假体可以通过旋转输送构件和阀保持器而旋转地对准天然瓣膜的天然连合，直到连合柱与天然瓣膜吻合对齐，旋转识别符可见。

48. 发明申请

US20100130852A1 NAVIGATION ENABLED LEAD DELIVERY CATHETER 审中-公开
标题翻译：导航启用导线导管
公开(公告)号：US20100130852A1
公开(公告)日：2010-05-27
申请号：US12275405
申请日：2008-11-21
申请人： Michael R. Neidert , Niall Duffy , Neil L. Purcell , Ronan Thornton
发明人： Michael R. Neidert , Niall Duffy , Neil L. Purcell , Ronan Thornton
IPC分类号： A61M25/092 , A61B5/055
CPC分类号： A61M25/0043 , A61M25/0045 , A61M25/005 , A61M2025/0024 , A61M2025/0025 , A61M2025/0681 , A61N1/056
摘要： A catheter system for positioning of a medical instrument that includes a first elongate member having a first lumen. The catheter system also includes a second elongate member that includes a second lumen that receives the medical instrument. The second elongate member is coupled directly to the first elongate member, and the second elongate member is operable to be at least partially segmented generally along a second longitudinal axis thereof to allow movement of the medical instrument outside the second lumen. The second elongate member is selectively collapsible and expandable to change a size of the second lumen.
摘要翻译：一种用于定位医疗器械的导管系统，其包括具有第一腔的第一细长构件。导管系统还包括第二细长构件，其包括接收医疗器械的第二腔。第二细长构件直接连接到第一细长构件，并且第二细长构件可操作以沿其第二纵向轴线至少部分地分段，以允许医疗器械在第二内腔外移动。第二细长构件选择性地可折叠和可膨胀以改变第二内腔的尺寸。

49. 发明申请

US20100030154A1 MEDICAL INSTRUMENT INSERTER 有权
标题翻译：医用仪器插件
公开(公告)号：US20100030154A1
公开(公告)日：2010-02-04
申请号：US12182659
申请日：2008-07-30
申请人： Niall Duffy
发明人： Niall Duffy
IPC分类号： A61M25/01
CPC分类号： A61M25/0668 , A61M2025/0188 , A61M2025/0675
摘要： A catheter system for positioning an instrument within a body that includes a hub defining a lumen therethrough for passage of the instrument toward the body. The catheter system also includes an elongate tubular member defining a lumen therethrough. The lumen of the elongate tubular member is in communication with the lumen of the hub for further passage of the instrument toward the body. The system also includes a slitter member that is coupled to the hub. The slitter member is disposed to slit the elongate tubular member as the elongate tubular member moves relative to the hub.
摘要翻译：一种用于将仪器定位在体内的导管系统，该导管系统包括限定通过其的腔的毂，用于使器械朝向身体通过。导管系统还包括限定通过其中的腔的细长管状构件。细长管状构件的内腔与毂的内腔连通，用于器械进一步通向身体。该系统还包括联接到轮毂的分切构件。分切构件设置成当细长管状构件相对于轮毂移动时切割细长管状构件。

50. 发明申请

US20090132019A1 Bifurcate Stent Delivery Catheter 审中-公开
标题翻译：分叉支架输送导管
公开(公告)号：US20090132019A1
公开(公告)日：2009-05-21
申请号：US11940515
申请日：2007-11-15
申请人： Niall Duffy , Ian Matheson
发明人： Niall Duffy , Ian Matheson
IPC分类号： A61F2/84 , A61F2/82
CPC分类号： A61F2/958 , A61F2/954 , A61F2/97 , A61F2002/065
摘要： A bifurcate stent delivery catheter is disclosed that includes a proximal shaft and two distal shaft branches having a bifurcated stent mounted thereon, wherein one or more conventional balloon catheters may be advanced within lumens of the bifurcate catheter to deploy the bifurcated stent. Since no balloons are mounted on the bifurcate catheter, the clinician may use any combination of balloon sizes for deploying various portions of the bifurcated stent and thus custom-select appropriate balloon sizes to best treat the bifurcation. Once a conventional balloon catheter is positioned within a distal shaft branch of the bifurcate stent delivery catheter, each of the distal shaft branches of the bifurcate catheter are constructed to split or otherwise expand in a controlled manner upon expansion of the balloon catheter in order to allow the bifurcated stent to be expanded or deployed.
摘要翻译：公开了一种分叉支架输送导管，其包括近端轴和具有安装在其上的分叉支架的两个远端轴分支，其中一个或多个常规气囊导管可以在分叉导管的腔内前进，以展开分叉支架。由于在分叉导管上没有安装气球，临床医生可以使用球囊尺寸的任何组合来展开分叉支架的各个部分，并且因此定制选择合适的气囊尺寸以最好地治疗分叉。一旦常规气囊导管定位在分叉支架输送导管的远端轴分支内，则分叉导管的每个远端轴分支被构造成在气囊导管膨胀时以受控的方式分开或以其它方式膨胀，以便允许分叉支架要扩大或部署。

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