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1. 发明授权

US09271856B2 Delivery catheter with distal moving capsule for transapical prosthetic heart valve delivery 有权
标题翻译：输送导管与远端移动胶囊用于经心假体心脏瓣膜递送
公开(公告)号：US09271856B2
公开(公告)日：2016-03-01
申请号：US13557488
申请日：2012-07-25
申请人： Niall Duffy , Ronan Rogers , John Gallagher , Gavin Kenny
发明人： Niall Duffy , Ronan Rogers , John Gallagher , Gavin Kenny
IPC分类号： A61F2/24 , A61F2/966 , A61F2/95
CPC分类号： A61F2/966 , A61F2/2436 , A61F2002/9505 , A61F2002/9517 , A61F2002/9665
摘要： Heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly with a rotatable control knob and a catheter including an introducer shaft, an intermediate shaft extending from the handle assembly, an inner shaft extending from the handle assembly, and a capsule for containing a prosthesis. The distal end of the capsule can be connected to a distal end of the inner shaft, which can be moved in a distal direction by the rotatable control knob to deploy the prosthesis. By advancing the introducer through the deployed prosthesis and retracting the capsule to mate with the introducer, a smooth profile can be created for retraction of the system through the deployed prosthesis, minimizing hang-ups and snagging.
摘要翻译：公开了使用输送导管递送和植入心脏瓣膜的心脏瓣膜输送系统和方法。输送系统可以包括具有可旋转控制旋钮的手柄组件和包括导引器轴的导管，从手柄组件延伸的中间轴，从手柄组件延伸的内轴以及用于容纳假体的胶囊。胶囊的远端可以连接到内轴的远端，其可以通过可旋转的控制旋钮在远端方向上移动以展开假体。通过推进引导器穿过部署的假体并缩回胶囊以与导引器配合，可以创建平滑的轮廓，用于通过部署的假体缩回系统，最大限度地减少挂起和阻塞。

2. 发明授权

US08518106B2 Catheter assembly with valve crimping accessories 有权
标题翻译：导管组件带阀门压接配件
公开(公告)号：US08518106B2
公开(公告)日：2013-08-27
申请号：US13016865
申请日：2011-01-28
申请人： Niall Duffy , Gerry McCaffrey , John Gallagher , Kate Corish , Ronan Rogers , Mark Casley , Gavin Kenny
发明人： Niall Duffy , Gerry McCaffrey , John Gallagher , Kate Corish , Ronan Rogers , Mark Casley , Gavin Kenny
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61F2/2436 , A61F2/95 , A61F2/966 , A61F2002/9517
摘要： Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. In one embodiment, a catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. A valve retaining mechanism can be included to assist in retaining the prosthetic valve prior to deployment. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.
摘要翻译：瓣膜输送导管组件包括当导管的远端通过膨胀的瓣膜然后从身体排出时限制扩张的假体瓣膜和主体通道的创伤的部件。在一个实施例中，根据本发明的导管组件包括手柄组件，导引器套和远侧末端组件。手柄组件可以包括固定的主手柄和允许使用者控制导管的远侧末端组件的两个或更多个旋转手柄。可以包括阀保持机构以在展开之前辅助保留人造瓣膜。手柄组件上的每个控制旋钮通过允许各种输送轴的精确操纵来控制导管的远侧末端上的部件的一部分。每个输送轴从手柄组件延伸到相对于导管远端的位置。

3. 发明申请

US20120035717A1 Catheter Assembly with Valve Crimping Accessories 有权
标题翻译：导管组件带阀门压接配件
公开(公告)号：US20120035717A1
公开(公告)日：2012-02-09
申请号：US13016865
申请日：2011-01-28
申请人： Niall Duffy , Gerry McCaffrey , John Gallagher , Kate Corish , Ronan Rogers , Mark CASLEY , Gavin Kenny
发明人： Niall Duffy , Gerry McCaffrey , John Gallagher , Kate Corish , Ronan Rogers , Mark CASLEY , Gavin Kenny
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61F2/2436 , A61F2/95 , A61F2/966 , A61F2002/9517
摘要： Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. In one embodiment, a catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. A valve retaining mechanism can be included to assist in retaining the prosthetic valve prior to deployment. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.
摘要翻译：瓣膜输送导管组件包括当导管的远端通过膨胀的瓣膜然后从身体排出时限制对扩张的假体瓣膜和主体通道的创伤的部件。在一个实施例中，根据本发明的导管组件包括手柄组件，导引器套和远侧末端组件。手柄组件可以包括固定的主手柄和允许使用者控制导管的远侧末端组件的两个或更多个旋转手柄。可以包括阀保持机构以在展开之前辅助保留人造瓣膜。手柄组件上的每个控制旋钮通过允许各种输送轴的精确操纵来控制导管的远侧末端上的部件的一部分。每个输送轴从手柄组件延伸到相对于导管远端的位置。

4. 发明申请

US20140031922A1 Delivery Catheter With Distal Moving Capsule for Transapical Prosthetic Heart Valve Delivery 有权
标题翻译：输送导管与远端假性心脏瓣膜输送的远端移动胶囊
公开(公告)号：US20140031922A1
公开(公告)日：2014-01-30
申请号：US13557488
申请日：2012-07-25
申请人： Niall Duffy , Ronan Rogers , John Gallagher , Gavin Kenny
发明人： Niall Duffy , Ronan Rogers , John Gallagher , Gavin Kenny
IPC分类号： A61F2/24
CPC分类号： A61F2/966 , A61F2/2436 , A61F2002/9505 , A61F2002/9517 , A61F2002/9665
摘要： Heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly with a rotatable control knob and a catheter including an introducer shaft, an intermediate shaft extending from the handle assembly, an inner shaft extending from the handle assembly, and a capsule for containing a prosthesis. The distal end of the capsule can be connected to a distal end of the inner shaft, which can be moved in a distal direction by the rotatable control knob to deploy the prosthesis. By advancing the introducer through the deployed prosthesis and retracting the capsule to mate with the introducer, a smooth profile can be created for retraction of the system through the deployed prosthesis, minimizing hang-ups and snagging.
摘要翻译：公开了使用输送导管递送和植入心脏瓣膜的心脏瓣膜输送系统和方法。输送系统可以包括具有可旋转控制旋钮的手柄组件和包括导引器轴的导管，从手柄组件延伸的中间轴，从手柄组件延伸的内轴以及用于容纳假体的胶囊。胶囊的远端可以连接到内轴的远端，其可以通过可旋转的控制旋钮在远端方向上移动以展开假体。通过推进引导器穿过部署的假体并缩回胶囊以与导引器配合，可以创建平滑的轮廓，用于通过部署的假体缩回系统，最大限度地减少挂起和阻塞。

5. 发明授权

US09717595B2 Trans-aortic delivery system with containment capsule centering device 有权
公开(公告)号：US09717595B2
公开(公告)日：2017-08-01
申请号：US13604150
申请日：2012-09-05
申请人： Declan Costello , Patrick Griffin , John Gallagher , Gavin Kenny , Edmond Sheahan
发明人： Declan Costello , Patrick Griffin , John Gallagher , Gavin Kenny , Edmond Sheahan
IPC分类号： A61F2/24 , A61F2/962 , A61F2/95
CPC分类号： A61F2/2436 , A61F2/962 , A61F2/966 , A61F2002/9517 , A61F2002/9665
摘要： Heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly which can include a first control mechanism, a second control mechanism, and a decoupling mechanism. The delivery systems can also include a delivery catheter extending from the handle assembly. The delivery catheter can include an outer shaft, which can be controlled by the first control mechanism; a prosthesis containing capsule comprising a proximal capsule portion connected to the outer shaft, and a distal capsule portion releasably coupled to the proximal capsule portion. After deploying a valve prosthesis, the capsule can be closed by activating the decoupling mechanism in the handle to rapidly close the distal and proximal capsule portions together. The delivery system can also include a centering element to guide the distal and proximal capsule portions together.

6. 发明申请

US20140067050A1 Trans-Aortic Delivery System With Containment Capsule Centering Device 有权
标题翻译：具有遏制胶囊定心装置的主动脉递送系统
公开(公告)号：US20140067050A1
公开(公告)日：2014-03-06
申请号：US13604150
申请日：2012-09-05
申请人： Declan Costello , Patrick Griffin , John Gallagher , Gavin Kenny , Edmond Sheahan
发明人： Declan Costello , Patrick Griffin , John Gallagher , Gavin Kenny , Edmond Sheahan
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/962 , A61F2/966 , A61F2002/9517 , A61F2002/9665
摘要： Heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly which can include a first control mechanism, a second control mechanism, and a decoupling mechanism. The delivery systems can also include a delivery catheter extending from the handle assembly. The delivery catheter can include an outer shaft, which can be controlled by the first control mechanism; a prosthesis containing capsule comprising a proximal capsule portion connected to the outer shaft, and a distal capsule portion releasably coupled to the proximal capsule portion. After deploying a valve prosthesis, the capsule can be closed by activating the decoupling mechanism in the handle to rapidly close the distal and proximal capsule portions together. The delivery system can also include a centering element to guide the distal and proximal capsule portions together.
摘要翻译：公开了使用输送导管递送和植入心脏瓣膜的心脏瓣膜输送系统和方法。输送系统可以包括手柄组件，其可以包括第一控制机构，第二控制机构和解耦机构。递送系统还可以包括从手柄组件延伸的递送导管。输送导管可包括可由第一控制机构控制的外轴; 包含胶囊的假体，其包括连接到所述外轴的近端胶囊部分和可释放地联接到所述近端胶囊部分的远端胶囊部分。在部署阀门假体之后，可以通过启动手柄中的解耦机构来关闭胶囊，以将远端和近端胶囊部分快速关闭在一起。输送系统还可以包括将远端和近端胶囊部分一起引导的定心元件。

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