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41. 发明申请

US20090157062A1 Systems and methods for treating glaucoma and systems and methods for imaging a portion of an eye 有权
标题翻译：用于治疗青光眼的系统和方法以及用于对眼睛的一部分进行成像的系统和方法
公开(公告)号：US20090157062A1
公开(公告)日：2009-06-18
申请号：US12000477
申请日：2007-12-13
申请人： Christoph Hauger , Peter Andrews , Werner Nahm , Ralf Kuschnereit , Martin Hacker , Gabor Scharioth
发明人： Christoph Hauger , Peter Andrews , Werner Nahm , Ralf Kuschnereit , Martin Hacker , Gabor Scharioth
IPC分类号： A61F9/008 , A61B18/20 , A61M27/00 , A61B3/13 , A61B3/14
CPC分类号： A61B3/13 , A61B3/102 , A61B3/14 , A61F9/008 , A61F2009/00868
摘要： Systems and methods are described for imaging an eye portion or for treating glaucoma in an eye of a patient. In a first step an optical microscopic image of a portion of the eye is acquired. In the optical microscopic image a distinguishable anatomical structure is identified to predict a location of a volume portion to be imaged three-dimensionally. Three-dimensional imaging of the located volume portion is performed by acquiring an optical coherence tomography image of the located volume portion. The volume portion is treated by either directing a laser beam to the volume portion or inserting an implant based on the OCT-image.
摘要翻译：描述了用于对眼部进行成像或用于治疗患者眼睛中的青光眼的系统和方法。在第一步骤中，获取眼睛的一部分的光学显微镜图像。在光学显微镜图像中，识别出可区分的解剖结构以预测待三维成像的体积部分的位置。通过获取定位体积部分的光学相干断层摄影图像来执行定位体积部分的三维成像。通过将激光束引导到体积部分或基于OCT图像插入植入物来处理体积部分。

42. 发明授权

US07508525B2 High efficiency balanced detection interferometer 失效
标题翻译：高效平衡检测干涉仪
公开(公告)号：US07508525B2
公开(公告)日：2009-03-24
申请号：US12150375
申请日：2008-04-28
申请人： Yan Zhou , Matthew J. Everett , Martin Hacker
发明人： Yan Zhou , Matthew J. Everett , Martin Hacker
IPC分类号： G01B9/02 , G01B11/02
CPC分类号： G01B9/02091 , G01B2290/40
摘要： An interferometer configured for use in optical coherence domain (OCT) reflectometry systems is disclosed. In the preferred embodiments, efficient routing of light and a balanced detection arrangement provide a high signal to noise ratio. In one set of embodiments, a pair of cascaded 2×2 couplers is used to split light along separate sample and reference paths and also for combining light returning from those paths and supplying the interfered collected light to the detection system. The interferometer can be used with various OCT modalities including time-domain and frequency domain approaches.
摘要翻译：公开了一种配置用于光学相干域（OCT）反射系统的干涉仪。在优选实施例中，光的有效路由和平衡检测装置提供高的信噪比。在一组实施例中，使用一对级联的2x2耦合器来沿独立的采样和参考路径分离光，并且还用于组合从那些路径返回的光并将受干扰的收集的光提供给检测系统。干涉仪可以与各种OCT模式一起使用，包括时域和频域方法。

43. 发明申请

US20070291277A1 Spectral domain optical coherence tomography system 审中-公开
标题翻译：光谱光学相干断层扫描系统
公开(公告)号：US20070291277A1
公开(公告)日：2007-12-20
申请号：US11820773
申请日：2007-06-20
申请人： Matthew Everett , Scott Meyer , Martin Hacker , Jochen Horn , Christopher Baker , Kabir Arianta , James Foley , Jochen Straub , Yue Qiu , David Landhuis , Claus Flachenecker , Clement Viard
发明人： Matthew Everett , Scott Meyer , Martin Hacker , Jochen Horn , Christopher Baker , Kabir Arianta , James Foley , Jochen Straub , Yue Qiu , David Landhuis , Claus Flachenecker , Clement Viard
IPC分类号： G01B11/02 , G01B9/02
CPC分类号： G01B9/02077 , A61B3/102 , G01B9/0203 , G01B9/02044 , G01B9/02091 , G01B2290/65 , G01B2290/70 , G01N21/4795
摘要： An ophthalmic imaging device for improved ophthalmic imaging including: an optical coherence scanning device, a fundus imaging device: an iris viewer; a motorized chin rest; an internal test target, and a fixation target device wherein the optical coherence scanning device, the ophthalmic scanning device, the iris viewer, and the fixation target device all share at least one common optical element. The optical coherence device preferably employs a Mach-Zehnder interferometer with an all fiber reference path; monitoring and attenuating power within the reference path. The multiple devices are separately and in combination aligned with the eye. The system includes internal and external calibration and improved image formats.
摘要翻译：一种用于改进眼科成像的眼科成像装置，包括：光学相干扫描装置，眼底成像装置：虹膜观察者; 机动下巴休息; 内部测试对象和固定目标设备，其中光学相干扫描设备，眼科扫描设备，虹膜观察器和固定目标设备都共享至少一个公共光学元件。光学相干装置优选采用具有全光纤参考路径的马赫 - 策德尔干涉仪; 在参考路径内监测和衰减功率。多个装置是分开的并且与眼睛组合对准。该系统包括内部和外部校准和改进的图像格式。

44. 发明申请

US20070034616A1 Method for processing materials with laser pulses having a large spectral bandwidth and device for carrying out said method 有权
标题翻译：使用具有大光谱带宽的激光脉冲处理材料的方法和用于执行所述方法的装置
公开(公告)号：US20070034616A1
公开(公告)日：2007-02-15
申请号：US10565582
申请日：2004-07-20
申请人： Mark Bischoff , Martin Hacker , Roland Sauerbrey , Gregor Stobrawa , Wolfgang Ziegler
发明人： Mark Bischoff , Martin Hacker , Roland Sauerbrey , Gregor Stobrawa , Wolfgang Ziegler
IPC分类号： B23K26/00
CPC分类号： B23K26/06 , B23K26/064
摘要： A method and device for processing materials with laser pulses having a large spectral bandwidth and a device for carrying out said method. The aim of the invention is to create an easy, flexible method enabling universally applicable processing which can, however, be adapted to specific processing and methodological requirements. According to the invention, one or several spectral parameters of the laser pulses, i.e. the spectral amplitude and/or spectral phase and/or spectral polarization thereof, is/are specifically modified, preferably according to a measuring process variable, in order to process material or during the occurrence of said processing. The invention is used in order to process material with laser pulses having a large spectral bandwidth, particularly femto-second pulses and pico-second pulses.
摘要翻译：一种用于利用具有大光谱带宽的激光脉冲处理材料的方法和装置以及用于执行所述方法的装置。本发明的目的是创建一种容易，灵活的方法，使得普遍适用的处理可以适应特定的处理和方法要求。根据本发明，激光脉冲的一个或几个光谱参数，即其光谱幅度和/或光谱相位和/或其光谱偏振被优选地根据测量过程变量进行修改，以便处理材料或在所述处理的发生期间。本发明用于处理具有大光谱带宽的激光脉冲的材料，特别是毫微微秒脉冲和微微秒脉冲。

45. 发明申请

US20060228011A1 Method and apparatus for measuring motion of a subject using a series of partial images from an imaging system 有权
公开(公告)号：US20060228011A1
公开(公告)日：2006-10-12
申请号：US11389351
申请日：2006-03-24
申请人： Matthew Everett , Claus Flachenecker , Martin Hacker , Scott Meyer , Keith O'Hara , Rick Williams
发明人： Matthew Everett , Claus Flachenecker , Martin Hacker , Scott Meyer , Keith O'Hara , Rick Williams
IPC分类号： G09G5/00 , G06K9/00
CPC分类号： A61B3/102 , A61B3/113
摘要： A line scan imager is used to determine the motion of a subject. Each line of image data from the line scan imager is compared with a reference image. The location of a matching line in the reference image reveals the displacement of the subject. The current subject displacement can be determined based on each line of image data. The resulting displacement information can be used to correctly place other optical beams on the subject. The method can be applied to tracking the human eye to facilitate measurement, imaging, or treatment with a beam of optical radiation.

46. 发明授权

US08857443B2 Method and arrangement for selecting an IOL and/or the surgical parameters within the framework of the IOL implantation on the eye 有权
标题翻译：用于在IOL植入眼睛框架内选择IOL和/或手术参数的方法和装置
公开(公告)号：US08857443B2
公开(公告)日：2014-10-14
申请号：US13483938
申请日：2012-05-30
申请人： Martin Hacker , Martin Kuehner , Rico Fuchs , Matthias Reich
发明人： Martin Hacker , Martin Kuehner , Rico Fuchs , Matthias Reich
IPC分类号： A61B19/00
CPC分类号： A61B3/0025 , A61B2034/108 , A61F2/1613 , G06F19/00 , G16H50/50
摘要： Selection of an appropriate intraocular lens (IOL) and/or the applicable surgical parameters for optimizing the results of refractive procedures on the eye. Features of the IOL are crucial for the selection and/or adjustment of the optimal IOL, but so is the IOL selection method (and parameters) from a surgical perspective. For the method, corresponding output parameters are determined from predetermined, estimated, or measured input parameters and/or their mean values, wherein at least two input parameters are varied with one another and which have at least one input parameter as a distribution function. The resulting function is optimized by means of corresponding target values and the determined distribution function of one or more output parameters is used as a decision aid. The present solution is used for selecting an appropriate IOL and/or the applicable surgical parameters and is applicable in the field of eye surgery for implanting IOLs.
摘要翻译：选择适当的眼内晶状体（IOL）和/或用于优化眼睛屈光程序结果的适用手术参数。 IOL的特征对于最佳IOL的选择和/或调整至关重要，而从手术角度来说，IOL选择方法（和参数）也是至关重要的。对于该方法，相应的输出参数由预定的，估计的或测量的输入参数和/或它们的平均值确定，其中至少两个输入参数彼此变化并且具有至少一个输入参数作为分布函数。所得到的函数通过相应的目标值进行优化，并且将一个或多个输出参数的确定的分布函数用作决策辅助。本解决方案用于选择适当的IOL和/或适用的外科手术参数，并且可用于眼部手术植入IOL的领域。

47. 发明授权

US08728062B2 Device and method for controlling a laser therapy of the eye 有权
标题翻译：用于控制眼睛激光治疗的装置和方法
公开(公告)号：US08728062B2
公开(公告)日：2014-05-20
申请号：US13070217
申请日：2011-03-23
申请人： Manfred Dick , Martin Hacker , Michael Kempe
发明人： Manfred Dick , Martin Hacker , Michael Kempe
IPC分类号： A61B18/20 , A61B3/10 , A61B5/15 , A61B5/00
CPC分类号： A61B3/102 , A61B5/0093 , A61B5/15 , A61F9/00821 , A61F2009/00851 , A61F2009/00863 , G01B9/02091
摘要： A device for controlling a laser therapy of the eye, including an evaluation unit that determines an intensity of a transient temperature effect by analysis of interferometric signals obtained from the eye and a control unit that controls the laser therapy, which is based on said transient temperature effect, the control unit being connected with said evaluation unit. A method for controlling a laser therapy of the eye, includes determination of the intensity of a transient temperature effect that is utilized for the control of the laser therapy, based on the effect, by analysis of interferometric signals.
摘要翻译：一种用于控制眼睛的激光治疗的装置，包括通过分析从眼睛获得的干涉信号和控制激光治疗的控制单元来确定瞬时温度效应的强度的评估单元，其基于所述瞬态温度所述控制单元与所述评估单元相连。用于控制眼睛的激光治疗的方法包括通过分析干涉信号来确定用于激光治疗的控制的瞬时温度效应的强度。

48. 发明申请

US20130308097A1 OPTIMIZED DEVICE FOR SWEPT SOURCE OPTICAL COHERENCE DOMAIN REFLECTOMETRY AND TOMOGRAPHY 有权
标题翻译：用于切割源的优化设备光学相关域反射光谱法和TOMOGRAPHY
公开(公告)号：US20130308097A1
公开(公告)日：2013-11-21
申请号：US13981688
申请日：2012-01-30
申请人： Ralf Ebersbach , Martin Hacker
发明人： Ralf Ebersbach , Martin Hacker
IPC分类号： A61B3/10
CPC分类号： A61B3/102 , G01B9/02004 , G01B9/02059 , G01B9/02091
摘要： Optimized device for swept source optical coherence domain reflectometry and tomography. In the coherence-optical device, light, with the aid of an interferometer, is used for distance-measuring and imaging purposes on reflecting and scattering areas of the human eye. The optimized device according to the invention consists of includes a tunable light source, matched to the sought-after measurement region ZOCT, with a resonator length LR, an interferometric measurement arrangement, a data capturing unit for capturing the light portions scattered back from the sample and a data processing unit. Here the resonator length LR of the tunable light source is matched not only to the sought-after measurement region ZOCT, but also to the entire interferometric measurement arrangement such that disturbance points present in the interferometric measurement arrangement cannot create disturbance signals in the sought-after measurement region ZOCT.
摘要翻译：扫频源光学相干域反射和层析成像的优化设备。在相干光学装置中，借助于干涉仪的光被用于在人眼的反射和散射区域上的距离测量和成像目的。根据本发明的优化装置包括与所寻找的测量区域ZOCT匹配的可调谐光源，具有谐振器长度LR，干涉测量装置，用于捕获从样品散射回来的光部分的数据捕获单元和数据处理单元。这里，可调谐光源的谐振器长度LR不仅与所寻求的测量区域ZOCT匹配，而且与整个干涉测量装置相匹配，使得存在于干涉测量装置中的干扰点不能产生所寻求的干扰信号测量区域ZOCT。

49. 发明授权

US08491122B2 Arrangement for attaining high-precision measurements of an eye 有权
标题翻译：用于获得眼睛高精度测量的布置
公开(公告)号：US08491122B2
公开(公告)日：2013-07-23
申请号：US13091836
申请日：2011-04-21
申请人： Martin Hacker , Scott A. Meyer
发明人： Martin Hacker , Scott A. Meyer
IPC分类号： A61B3/14
CPC分类号： A61B3/152
摘要： A solution for attaining high-precision and reproducible measurements during opthalmological biometry and imaging includes an illumination unit for producing a fixation marker, a device for transmitting the light of the produced fixation marker into the eye, a measurement device and a control unit. The illumination unit includes a device for the targeted change of the beam direction of the produced fixation marker. A camera for the detection of the line of vision of the eye is connected to the control unit. The control unit determines the sufficient congruity between detected line of vision and displayed beam direction of the produced fixation marker and, in dependence of the degree of probability of the congruity, triggers a measurement. The suggested arrangement is applicable for opthalmological diagnostic devices, which exhibit a camera and a measuring system, whereby measurements can be taken in all areas of the eye.
摘要翻译：用于在眼科生物测定和成像期间获得高精度和可再现的测量的解决方案包括用于产生固定标记的照明单元，用于将产生的定影标记的光透射到眼睛中的装置，测量装置和控制单元。照明单元包括用于靶向改变所产生的定影标记的光束方向的装置。用于检测眼睛视线的相机连接到控制单元。控制单元确定检测到的视线与所产生的固定标记的显示光束方向之间的足够的一致性，并且根据一致性概率的程度触发测量。该建议的布置适用于展示相机和测量系统的眼科诊断装置，由此可以在眼睛的所有区域进行测量。

50. 发明申请

US20130107209A1 SYSTEM FOR THE IMPROVED IMAGING OF EYE STRUCTURES 有权
标题翻译：改善眼睛结构成像的系统
公开(公告)号：US20130107209A1
公开(公告)日：2013-05-02
申请号：US13696030
申请日：2011-04-23
申请人： Martin Hacker , Rudolf Murai von Bünau , Burkhard Wagner
发明人： Martin Hacker , Rudolf Murai von Bünau , Burkhard Wagner
IPC分类号： A61B3/10
CPC分类号： A61B3/102 , A61B3/107 , A61B5/0066 , G01N21/4795 , G01N2021/1787
摘要： A system for the improved imaging of eye structures based on optical coherence tomography. The system includes an interferometric measuring arrangement, which has an optical element arranged in the measurement arm or reference arm for influencing the polarization state of the light before the light is interferometrically superimposed, a scanning unit arranged in the measurement arm for implementing OCT scans, a detector for recording the produced interference pattern, and an evaluating and documenting unit. At least two different polarization states of the light are produced. The interference patterns produced in the interferometric measuring arrangement are recorded and forwarded to the evaluating and documenting unit which reconstructs OCT scans from the transmitted interference patterns, combines the OCT scans, and presents and/or stores the resulting OCT signals. The system can be used for pachymetry in addition to the pre- and post-operative imaging for analysis and measurement.
摘要翻译：一种基于光学相干断层扫描的改善眼结构成像的系统。该系统包括干涉测量装置，其具有布置在测量臂或参考臂中的光学元件，用于在光被干涉地叠加之前影响光的偏振状态;布置在测量臂中用于实现OCT扫描的扫描单元，用于记录产生的干涉图案的检测器，以及评估和记录单元。产生光的至少两种不同的偏振态。在干涉测量装置中产生的干涉图案被记录并转发给评估和记录单元，其从发射的干涉图案重建OCT扫描，组合OCT扫描，并呈现和/或存储所得到的OCT信号。除了用于分析和测量的术前和术后成像，该系统可用于深度测量。

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