专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明申请

WO2007027875A2 RANDOMIZED STIMULATION OF A GASTROINTESTINAL ORGAN 审中-公开
标题翻译： GASTROINTESTINAL ORGAN的随机刺激
公开(公告)号：WO2007027875A2
公开(公告)日：2007-03-08
申请号：PCT/US2006/034003
申请日：2006-08-31
申请人： INTRAPACE, INC. , IMRAN, Mir, A.
发明人： IMRAN, Mir, A.
IPC分类号： A61N1/32
CPC分类号： A61N1/36007
摘要： A device, system and method for stimulating a digestive organ is provided where the stimulation is randomized.
摘要翻译：提供用于刺激消化器官的装置，系统和方法，其中刺激是随机化的。

42. 发明申请

WO2017151986A1 URETHRAL CATHETERS AND METHODS FOR FACILITATED INTRODUCTION INTO THE URINARY TRACT 审中-公开
标题翻译：尿道导管及其辅助引入泌尿道的方法
公开(公告)号：WO2017151986A1
公开(公告)日：2017-09-08
申请号：PCT/US2017/020543
申请日：2017-03-02
申请人： IMRAN, Mir
发明人： IMRAN, Mir
IPC分类号： A61M25/01 , A61N1/36
摘要： Embodiments of the invention provide apparatus, systems and methods for facilitating introduction of a urinary drainage catheter (UDC) into the urinary tract (UT). One embodiment provides a UDC including electrodes for delivering high frequency current to a patient's pudenal nerves to relax the urinary sphincter (US) before passing the UDC therethrough so as reduce the resistance force on the UDC and discomfort to the patient. The electrodes can comprise at least one pair of bipolar electrodes and may be flexible so as to bend and flex within the urethra. The UDC includes one or more lumens including a drainage lumen and an inflation lumen for inflating an anchoring device on the UDC. The UDC can include a pressure sensor to assess relaxation of the US. The UDC may include a second set of electrodes and irrigation lumen for relaxing the US and flushing the urethra with the UDC in place.
摘要翻译：本发明的实施例提供了便于将尿液引流导管（UDC）引入泌尿道（UT）的装置，系统和方法。一个实施例提供了一种UDC，其包括用于将高频电流递送至患者的皮神经的电极，以便在使UDC通过UDC之前松弛尿道括约肌（US），从而减小UDC上的阻力和患者的不适。电极可以包括至少一对双极电极并且可以是柔性的以便在尿道内弯曲和弯曲。 UDC包括一个或多个管腔，该管腔包括排出管腔和膨胀管腔，用于给UDC上的锚定装置充气。 UDC可以包括一个压力传感器来评估美国的放松。 UDC可以包括第二组电极和灌洗腔，用于放松美国并用UDC冲洗尿道。

43. 发明申请

WO2016183374A1 DEVICE, SYSTEM AND METHODS FOR MEASUREMENT OF PRESSURES IN THE URINARY TRACT 审中-公开
标题翻译：用于测量尿路压力的装置，系统和方法
公开(公告)号：WO2016183374A1
公开(公告)日：2016-11-17
申请号：PCT/US2016/032203
申请日：2016-05-12
申请人： IMRAN, Mir , TRANCHINA, Ben
发明人： IMRAN, Mir , TRANCHINA, Ben
IPC分类号： A61B5/20 , A61B5/02 , A61B5/021 , A61B5/0215 , A61B5/04 , A61M25/00
CPC分类号： A61B5/205 , A61B5/6853 , A61M25/0017 , A61M25/1018 , A61M2025/0003 , A61M2025/0036 , A61M2210/1078 , A61M2210/1085 , A61N1/0551
摘要： A catheter for measuring pressure in the urinary tract of a patient. A plurality of lumens is formed in the catheter body, and an adaptor is coupled to the proximal end of the catheter body. The adaptor includes a port for each lumen. A first pressure sensor, typically including a balloon, is fluidically coupled to a first lumen and is configured and positioned to measure pressure in a urethra of the patient. A second pressure sensor, also typically including a balloon, is fluidically coupled to a second lumen and is configured and positioned on the catheter body to measure pressure in a bladder of the patient. An expandable retention member, which may be coupled to a third lumen, is positioned on the catheter body between the first and second expandable pressure sensors so that the catheter body may be retained at a selected location.
摘要翻译：用于测量患者尿道压力的导管。在导管主体中形成多个内腔，并且适配器联接到导管主体的近端。适配器包括每个管腔的端口。通常包括气囊的第一压力传感器流体耦合到第一内腔，并被构造和定位成测量患者尿道中的压力。也通常包括气囊的第二压力传感器流体耦合到第二腔，并被配置并定位在导管主体上以测量患者膀胱中的压力。可连接到第三腔的可扩张保留构件位于第一和第二可膨胀压力传感器之间的导管主体上，使得导管主体可以保持在选定位置。

44. 发明申请

WO2015176031A2 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR FABRICATION OF SOLID MASSES COMPRISING POLYPEPTIDES AND/OR PROTEINS 审中-公开
标题翻译：用于制造包含多肽和/或蛋白质的固体组合物的药物组合物和方法
公开(公告)号：WO2015176031A2
公开(公告)日：2015-11-19
申请号：PCT/US2015031239
申请日：2015-05-15
申请人： INCUBE LABS LLC , MORALES MERCEDES , IMRAN MIR , KORUPOLU RADHIKA , HASHIM MIR
发明人： MORALES MERCEDES , IMRAN MIR , KORUPOLU RADHIKA , HASHIM MIR
IPC分类号： G06Q50/22 , G06F19/00
CPC分类号： A61K38/28 , A61K9/2018 , A61K9/2027 , A61K9/2031 , A61K9/2072 , A61K9/2077 , A61K38/26 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/24 , C07K2317/76
摘要： Embodiments of the invention provide shaped masses comprising one or more drugs such as proteins or polypeptides and methods for forming such shaped masses. One embodiment provides a shaped mass comprising a drug such as a protein or polypeptide having a biological activity in the body of a mammal. The shaped mass is formed by compression of a precursor material comprising the drug wherein an amount of biologically active drug in the mass is a preserved above a minimum level. Drugs which may be incorporated into the shaped mass may include one or more glucose regulating proteins such as insulin, incretins; and immunoglobulins such as TNF-inhibiting antibodies or interleukin neutralizing antibodies. Embodiments of the shaped mass may be incorporated into a tissue penetrating member which is inserted into the intestinal wall allowing for the oral delivery of proteins and peptides which would otherwise be degraded in the intestinal tract.
摘要翻译：本发明的实施方案提供包含一种或多种药物如蛋白质或多肽的成形物质以及用于形成这种成形物质的方法。一个实施方案提供了包含药物例如在哺乳动物体内具有生物活性的蛋白质或多肽的成形团块。成形物质通过压缩包含药物的前体材料而形成，其中所述物质中的生物活性药物的量保持在最低水平以上。可以掺入成形物质中的药物可以包括一种或多种葡萄糖调节蛋白，例如胰岛素，肠降血糖素; 和免疫球蛋白例如TNF抑制性抗体或白细胞介素中和抗体。成形物质的实施方式可以被结合到组织穿透构件中，该组织穿透构件被插入到肠壁中，从而允许蛋白质和肽的口服递送，否则这些蛋白质和肽将在肠道中降解。

45. 发明申请

WO2013052708A1 SOLID DRUG DELIVERY APPARATUS, FORMULATIONS AND METHODS OF USE 审中-公开
标题翻译：固体药物递送装置，制剂和使用方法
公开(公告)号：WO2013052708A1
公开(公告)日：2013-04-11
申请号：PCT/US2012/058813
申请日：2012-10-04
申请人： INCUBE LABS, LLC , IMRAN, Mir
发明人： IMRAN, Mir
IPC分类号： A61M1/00
CPC分类号： A61K31/635 , A61M5/14276 , A61M37/0069 , A61M2205/04
摘要： Embodiments provide apparatus and methods for delivering solid form medications such as pellets to various locations in the body. One embodiment provides an apparatus for in vivo delivery of medication pellets comprising a housing including a port, a pellet-containing belt disposed in the housing, and a mechanism for transferring the pellets from the belt to a delivery site (DS) outside the housing. Each pellet contains a dose of drug to treat a medical condition. An elongate member is coupled to the housing and includes a lumen for pellet delivery, a proximal end coupled to the port and a distal end positioned at the DS. The pellet can be delivered to the DS at regular intervals or responsive to a detected biological event. Embodiments of the invention are particularly useful for delivering medication to treat a medical condition over an extended period without requiring a patient to take external medication.
摘要翻译：实施例提供了用于将诸如颗粒的固体形式药物递送到身体中的各个位置的装置和方法。一个实施方案提供用于体内递送药物丸粒的装置，其包括壳体，该壳体包括端口，设置在壳体中的包含粒料的带以及用于将粒料从带传送到壳体外部的输送部位（DS）的机构。每个丸剂含有一定剂量的药物以治疗病情。细长构件联接到壳体并且包括用于颗粒递送的内腔，联接到端口的近端和位于DS处的远端。颗粒可以定期递送到DS，或响应于检测到的生物事件。本发明的实施方案特别可用于递送药物以在长时间内治疗医疗状况，而不需要患者服用外部药物。

46. 发明申请

WO2012149227A3 MOUTHPIECE FOR MEASUREMENT OF BIOMETRIC DATA OF A DIVER AND UNDERWATER COMMUNICATION 审中-公开
标题翻译：用于测量潜水和水下通信的生物量数据的意义
公开(公告)号：WO2012149227A3
公开(公告)日：2013-01-24
申请号：PCT/US2012035310
申请日：2012-04-26
申请人： INCUBE LABS LLC , IMRAN MIR
发明人： IMRAN MIR
IPC分类号： A61B5/1455 , A61B1/24 , A61B5/08
CPC分类号： A61B5/0002 , A61B5/0816 , A61B5/14551 , A61B5/6803 , A61B5/682 , A61B2562/0204 , A61B2562/0238 , B63C11/186 , B63C11/26
摘要： Embodiments of the invention provide a system, apparatus and methods for measurement of biometric data of a diver. In many embodiments, the system includes a mouthpiece having a sensor device comprising a light emitter and detector configured to emit and detect light at a wavelength having an absorbance correlated with a level of a blood gas saturation e.g., oxygen, nitrogen, C02,. The emitter is positioned to emit light onto oral tissue of the diver and the detector positioned to detect light which is received from the oral tissue either by transmittance of light through the oral tissue or by reflection of light from the tissue. The target oral tissue can include one or both of gum or buccal tissue. Such embodiments allow data to be collected without having to wear additional sensors or measurement devices and allow for measurement of blood gas levels as the diver breaths through their mouthpiece.
摘要翻译：本发明的实施例提供了一种用于测量潜水员的生物特征数据的系统，装置和方法。在许多实施例中，该系统包括具有传感器装置的接口管，该传感器装置包括光发射器和检测器，其被配置为发射和检测具有与血液饱和度例如氧气，氮气，CO 2等级相关的吸光度的波长的光。发射器被定位成将光发射到潜水员的口腔组织上，并且检测器被定位成通过透过口腔组织的光的透射或通过来自组织的光的反射来检测从口腔组织接收的光。目标口腔组织可以包括口香糖或口腔组织中的一种或两种。这样的实施例允许收集数据而不必佩戴附加的传感器或测量装置，并允许当潜水员通过其喉舌呼吸时测量血液气体水平。

47. 发明申请

WO2012154704A2 SYSTEM AND METHOD FOR BIPHASIC TRANSDERMAL IONTOPHORETIC DELIVERY OF THERAPEUTIC AGENTS FOR THE CONTROL OF ADDICTIVE CRAVINGS 审中-公开
标题翻译：用于控制附加治疗的治疗药物的双向超声波输送的系统和方法
公开(公告)号：WO2012154704A2
公开(公告)日：2012-11-15
申请号：PCT/US2012/036857
申请日：2012-05-07
申请人： INCUBE LABS, LLC , IMRAN, Mir , IMRAN, Talat , HASHIM, Mir
发明人： IMRAN, Mir , IMRAN, Talat , HASHIM, Mir
IPC分类号： A61N1/30 , A61N1/04 , A61M37/00 , A61K9/70
CPC分类号： A61N1/30 , A61K9/0009 , A61K9/0014 , A61K31/465 , A61N1/0432 , A61N1/0448 , A61N1/303 , A61N1/325
摘要： Embodiments of the invention provide methods for the transdermal delivery of therapeutic agents for the treatment of addictive cravings e.g., nicotine compounds for the treatment of nicotine cravings from tobacco use. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient.
摘要翻译：本发明的实施方案提供了用于治疗成瘾性渴望的治疗剂的透皮递送方法，例如用于治疗来自烟草使用的尼古丁渴望的尼古丁化合物。用于这种传送的方法的实施例包括将至少一个电极组件定位成与患者的皮肤电连通。组合物包括包含被动地扩散入皮肤的治疗剂的溶液。使用具有例如极性和大小的特性的第一电流，在第一时段期间，将剂量的药剂从组合物输送到皮肤中，以将药剂排斥出组合体。在第二时段期间，使用具有吸引剂的特性的第二电流将试剂保持在组合中，使得药剂递送到皮肤中最小化。可以根据患者的输入要求递送剂量。

48. 发明申请

WO2012154697A2 SYSTEM AND METHOD FOR ENHANCING SPEECH OF A DIVER WEARING A MOUTHPIECE 审中-公开
标题翻译：用于增强潜水员口音的系统和方法
公开(公告)号：WO2012154697A2
公开(公告)日：2012-11-15
申请号：PCT/US2012/036845
申请日：2012-05-07
申请人： INCUBE LABS, LLC , IMRAN, Mir
发明人： IMRAN, Mir
IPC分类号： G10L21/02 , B63C11/26 , B63C11/12
CPC分类号： G10L21/0364 , B63C11/26 , G10L13/00 , G10L13/033 , G10L2021/03643 , H04B11/00 , H04B13/005 , H04B13/02 , H04R1/44 , H04R1/46
摘要： Embodiments described herein provide a system, apparatus and methods to enable a diver to communicate more clearly with other divers or locations. Embodiments process the speech to add clarity, or otherwise convert speech into an outputted form that is more intelligible e.g. so as to simulate the diver's unhindered speech. Embodiments provide hardware and software for receiving and recognizing hindered speech of a diver (e.g., speech hindered by a mouthpiece) and then augmenting the speech with generated output sounds corresponding to the intended speech sound or generating or replacing at least some of the diver's speech with synthesized words. The output sounds may be in the speaker's own voice or a synthesized voice. Embodiments may be configured to add clarity to and/or augment speech that is hindered by the wearing of a mouthpiece from a snorkel, SCUBA or other diving apparatus.
摘要翻译：本文描述的实施例提供了使潜水员能够与其他潜水员或位置更清楚地通信的系统，装置和方法。实施例处理语音以增加清晰度，或以其它方式将语音转换为更易理解的输出形式。以模拟潜水员不受阻碍的演讲。实施例提供了用于接收和识别潜水员（例如，由喉舌阻碍的语音）的受阻语音的硬件和软件，然后用对应于预期语音的生成的输出声音来增加语音，或者用至少一些潜水员的语音产生或替换合成词。输出声音可能在扬声器自己的声音或合成声音中。实施例可以被配置为增加通过来自浮潜，SCUBA或其它潜水装置的接口管的磨损而妨碍的语音的清晰度和/或增加语音。

49. 发明申请

WO2012129576A2 SYSTEM AND METHOD FOR BIPHASIC TRANSDERMAL IONTOPHREOTIC DELIVERY OF THERAPEUTIC AGENTS 审中-公开
标题翻译：系统和方法用于治疗药物的双向透皮递送
公开(公告)号：WO2012129576A2
公开(公告)日：2012-09-27
申请号：PCT/US2012/030633
申请日：2012-03-26
申请人： INCUBE LABS, LLC , IMRAN, Mir , HASHIM, Mir , MCLAUGHLIN, Glen , ARASTU, Huma , VAIDYANATHAN, Rekha , HARRIS, Joel , KORUPOLU, Radhika , MANGOGNA, Andrew , ONG, Chang , PATEL, Sanjay , WANG, Lu , WILLIAMS, Timothy
发明人： IMRAN, Mir , HASHIM, Mir , MCLAUGHLIN, Glen , ARASTU, Huma , VAIDYANATHAN, Rekha , HARRIS, Joel , KORUPOLU, Radhika , MANGOGNA, Andrew , ONG, Chang , PATEL, Sanjay , WANG, Lu , WILLIAMS, Timothy
IPC分类号： A61N1/30 , A61N1/36 , A61N1/04 , A61K9/70
CPC分类号： A61N1/325 , A61K9/0009 , A61K9/0014 , A61K31/4178 , A61K31/4468 , A61K31/454 , A61K31/5415 , A61N1/0436 , A61N1/044 , A61N1/0448 , A61N1/30 , A61N1/303
摘要： Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.
摘要翻译：各种实施方案提供用于治疗剂的双相离子电渗透皮递送的方法和系统。用于这种递送的方法的实施例包括将至少一个电极组件定位成与患者的皮肤电通信。该组件包括包含被动扩散到皮肤中的治疗剂的溶液。在第一阶段期间，使用具有例如极性和大小等特征的第一电流将剂量的药剂从组件递送到皮肤中，以将药剂排出组件。在第二阶段期间，具有吸引药剂的特征的第二电流被用于将药剂保持在组件中，使得药剂递送到皮肤中被最小化。一剂药剂可以通过来自患者的输入按需递送。实施例可以用于递送引起不希望的被动扩散的不利影响的试剂。

50. 发明申请

WO2012040254A3 DEVICE, SYSTEM AND METHOD FOR MONITORING AND COMMUNICATING BIOMETRIC DATA OF A DIVER 审中-公开
标题翻译：用于监测和传播潜水生物量数据的装置，系统和方法
公开(公告)号：WO2012040254A3
公开(公告)日：2012-06-28
申请号：PCT/US2011052429
申请日：2011-09-20
申请人： INCUBE LABS LLC , IMRAN MIR
发明人： IMRAN MIR
IPC分类号： A61B5/145 , A61B5/02 , A61B5/1455 , H04B7/24
CPC分类号： A61B5/14551 , A61B5/0002 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/02416 , A61B5/0816 , A61B5/6826 , A61B5/6831 , A61B5/7228 , A61B5/7278 , A61B5/7296 , A61B5/7405 , A61B5/746 , A61B2560/0214 , A61B2560/0242 , A61B2560/0247 , A61B2560/0252 , A61B2562/18 , B63B22/00 , B63B35/00 , B63B2035/007 , B63C11/02 , B63C11/26
摘要： A system and method for monitoring biometric data of a diver and signaling those data from a first communication device to other communication devices, e.g., those of other divers, on a ship or buoy. A signal generated from a device of the diver can generate a diver identifier, an indication of a stress state of the diver and the diver's location.
摘要翻译：一种用于监测潜水员的生物特征数据并将这些数据从第一通信设备发送到其他通信设备（例如其他潜水员在船舶或浮标上的通信设备）的系统和方法。从潜水员的装置产生的信号可以产生潜水员标识符，潜水员的应力状态和潜水者位置的指示。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式