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41. 发明申请

US20120227471A1 SAMPLING PROBES, SYSTEMS, APPARATUSES, AND METHODS 有权
标题翻译：采样探针，系统，装置和方法
公开(公告)号：US20120227471A1
公开(公告)日：2012-09-13
申请号：US13411337
申请日：2012-03-02
申请人： Wesley SMITH , Glen DAVIS , John JACKSON , Gregory KADUCHAK , Michael WARD
发明人： Wesley SMITH , Glen DAVIS , John JACKSON , Gregory KADUCHAK , Michael WARD
IPC分类号： G01N1/10
CPC分类号： G01N35/1011 , G01N15/1404 , G01N35/0099
摘要： A sampling system is provided. The sampling system includes a housing. Mounted to the housing is a Hall effect sensor. A probe configured to contact a sample is inserted into the housing. The probe includes an elongated portion and a restorative spring inserted onto the elongated portion of the probe. The restorative spring provides sufficient restorative force to return the probe to a relaxed position. The Hall effect sensor is configured to sense a field strength generated by the proximity of the restorative spring of the probe in the extended position.
摘要翻译：提供采样系统。采样系统包括壳体。安装到外壳是霍尔效应传感器。被配置成接触样品的探针被插入壳体中。探针包括细长部分和插入到探针的细长部分上的修复弹簧。修复弹簧提供足够的修复力以将探头返回到松弛位置。霍尔效应传感器被配置为感测由延伸位置处的探头的修复弹簧附近产生的场强。

42. 发明申请

US20090162887A1 Particle analysis in an acoustic cytometer 有权
公开(公告)号：US20090162887A1
公开(公告)日：2009-06-25
申请号：US12283491
申请日：2008-09-11
申请人： Gregory Kaduchak , Michael D. Ward
发明人： Gregory Kaduchak , Michael D. Ward
IPC分类号： C12N5/06 , C12Q1/02 , G01N1/00 , B07B13/04
CPC分类号： G01N29/14 , B01L3/502761 , B01L2200/0636 , B01L2200/0652 , B01L2300/0838 , B01L2300/0864 , B01L2400/0439 , B01L2400/0487 , G01N15/1404 , G01N15/1459 , G01N15/1463 , G01N33/4833 , G01N2001/4094 , G01N2015/1081 , G01N2015/1415 , G01N2015/142 , G01N2015/149
摘要： The present invention is a method and apparatus for acoustically manipulating one or more particles.

43. 发明申请

US20090158823A1 Particle analysis in an acoustic cytometer 有权
标题翻译：声学细胞仪中的粒子分析
公开(公告)号：US20090158823A1
公开(公告)日：2009-06-25
申请号：US12283461
申请日：2008-09-11
申请人： Gregory Kaduchak , Michael D. Ward
发明人： Gregory Kaduchak , Michael D. Ward
IPC分类号： G01N15/06 , G01N1/10
CPC分类号： G01N29/14 , B01L3/502761 , B01L2200/0636 , B01L2200/0652 , B01L2300/0838 , B01L2300/0864 , B01L2400/0439 , B01L2400/0487 , G01N15/1404 , G01N15/1459 , G01N15/1463 , G01N33/4833 , G01N2001/4094 , G01N2015/1081 , G01N2015/1415 , G01N2015/142 , G01N2015/149
摘要： The present invention is a method and apparatus for acoustically manipulating one or more particles.
摘要翻译：本发明是用于声学地操纵一个或多个颗粒的方法和装置。

44. 发明申请

US20090139332A1 Method for non-contact particle manipulation and control of particle spacing along an axis 有权
标题翻译：非接触式颗粒操纵和沿着轴线控制颗粒间距的方法
公开(公告)号：US20090139332A1
公开(公告)日：2009-06-04
申请号：US12288896
申请日：2008-10-23
申请人： Gregory Russ Goddard , Gregory Kaduchak , James Hubert Jett , Steven Wayde Graves
发明人： Gregory Russ Goddard , Gregory Kaduchak , James Hubert Jett , Steven Wayde Graves
IPC分类号： G01H17/00
CPC分类号： G01N15/1404 , G01N15/1484 , G01N2015/142 , G01N2015/149 , Y10T137/206
摘要： Method and system for uniformly spacing particles in a flowing system comprising suspending particles in an elongated fluid filled cavity; exposing said cavity to an axial acoustic standing wave field, wherein said axial acoustic standing wave field drives said particles to nodal and anti-nodal positions along the center axis of said cavity to result in uniformly spaced particles; and focusing said particles to the center axis of said cavity.
摘要翻译：用于在流动系统中均匀间隔颗粒的方法和系统，包括将颗粒悬浮在细长的流体填充空腔中; 将所述空腔暴露于轴向声驻波场，其中所述轴向声驻波场沿着所述空腔的中心轴线将所述颗粒驱动到节点和反节点位置，以产生均匀间隔的颗粒; 并将所述颗粒聚焦到所述空腔的中心轴线上。

45. 发明申请

US20090042239A1 Particle Fusing Systems and Methods Using Acoustic Radiation Pressure 有权
标题翻译：使用声辐射压力的粒子定影系统和方法
公开(公告)号：US20090042239A1
公开(公告)日：2009-02-12
申请号：US12239483
申请日：2008-09-26
申请人： Michael D. Ward , Gregory Kaduchak
发明人： Michael D. Ward , Gregory Kaduchak
IPC分类号： C12Q1/02 , C12N13/00 , C12N5/16
CPC分类号： G01N15/1404 , A61M1/3678 , G01N15/12 , G01N15/147 , G01N21/1702 , G01N21/64 , G01N21/6428 , G01N21/645 , G01N27/447 , G01N29/222 , G01N33/56966 , G01N2015/1409 , G01N2015/1415 , G01N2015/142 , G01N2291/02416 , G01N2291/02809 , G01N2291/02836 , Y10T436/101666 , Y10T436/25 , Y10T436/25375 , Y10T436/25625 , Y10T436/2575
摘要： The present invention comprises methods and systems that use acoustic radiation pressure.
摘要翻译：本发明包括使用声辐射压力的方法和系统。

46. 发明申请

US20090029870A1 Particle Analyzing Systems and Methods Using Acoustic Radiation Pressure 有权
标题翻译：使用声辐射压力的粒子分析系统和方法
公开(公告)号：US20090029870A1
公开(公告)日：2009-01-29
申请号：US12239453
申请日：2008-09-26
申请人： Michael D. Ward , Gregory Kaduchak
发明人： Michael D. Ward , Gregory Kaduchak
IPC分类号： C40B30/04 , C12Q1/02 , B03C1/02 , G01N27/74
CPC分类号： G01N15/1404 , A61M1/3678 , G01N15/12 , G01N15/147 , G01N21/1702 , G01N21/64 , G01N21/6428 , G01N21/645 , G01N27/447 , G01N29/222 , G01N33/56966 , G01N2015/1409 , G01N2015/1415 , G01N2015/142 , G01N2291/02416 , G01N2291/02809 , G01N2291/02836 , Y10T436/101666 , Y10T436/25 , Y10T436/25375 , Y10T436/25625 , Y10T436/2575
摘要： The present invention comprises methods and systems that use acoustic radiation pressure.
摘要翻译：本发明包括使用声辐射压力的方法和系统。

47. 发明申请

US20080245745A1 Acoustic concentration of particles in fluid flow 有权
标题翻译：流体流中颗粒的声学浓度
公开(公告)号：US20080245745A1
公开(公告)日：2008-10-09
申请号：US11784936
申请日：2007-04-09
申请人： Michael D. Ward , Gregory Kaduchak
发明人： Michael D. Ward , Gregory Kaduchak
IPC分类号： B01D35/06 , B01D29/00
CPC分类号： G01N1/4077 , C12M47/02 , G01N2001/4094
摘要： An apparatus for acoustic concentration of particles in a fluid flow includes a substantially acoustically transparent membrane and a vibration generator that define a fluid flow path therebetween. The fluid flow path is in fluid communication with a fluid source and a fluid outlet and the vibration generator is disposed adjacent the fluid flow path and is capable of producing an acoustic field in the fluid flow path. The acoustic field produces at least one pressure minima in the fluid flow path at a predetermined location within the fluid flow path and forces predetermined particles in the fluid flow path to the at least one pressure minima.
摘要翻译：用于流体流中的颗粒声学浓缩的装置包括基本上声透明的膜和在其间限定流体流路的振动发生器。流体流动路径与流体源和流体出口流体连通，并且振动发生器邻近流体流动路径布置并且能够在流体流动路径中产生声场。该声场在流体流动路径内的预定位置处在流体流动路径中产生至少一个压力最小值，并且迫使流体流动路径中的预定粒子达到至少一个压力最小值。

48. 发明授权

US06467350B1 Cylindrical acoustic levitator/concentrator 有权
标题翻译：圆柱形声音升降机/集中器
公开(公告)号：US06467350B1
公开(公告)日：2002-10-22
申请号：US09810905
申请日：2001-03-15
申请人： Gregory Kaduchak , Dipen N. Sinha
发明人： Gregory Kaduchak , Dipen N. Sinha
IPC分类号： B01D1706
CPC分类号： B01D49/006
摘要： A low-power, inexpensive acoustic apparatus for levitation and/or concentration of aerosols and small liquid/solid samples having particulates up to several millimeters in diameter in air or other fluids is described. It is constructed from a commercially available, hollow cylindrical piezoelectric crystal which has been modified to tune the resonance frequency of the breathing mode resonance of the crystal to that of the interior cavity of the cylinder. When the resonance frequency of the interior cylindrical cavity is matched to the breathing mode resonance of the cylindrical piezoelectric transducer, the acoustic efficiency for establishing a standing wave pattern in the cavity is high. The cylinder does not require accurate alignment of a resonant cavity. Water droplets having diameters greater than 1 mm have been levitated against the force of gravity using; less than 1 W of input electrical power. Concentration of aerosol particles in air is also demonstrated.
摘要翻译：描述了用于悬浮和/或浓缩气溶胶的低功率，廉价的声学设备和在空气或其它流体中直径达数毫米的微粒的小液体/固体样品。它由市售的中空圆柱形压电晶体构成，其经修改以调节晶体的呼吸模式共振的谐振频率与气缸的内腔的共振频率。当内部圆柱形空腔的共振频率与圆柱形压电换能器的呼吸模式共振相匹配时，用于在空腔中建立驻波模式的声学效率高。气缸不需要精确对准谐振腔。直径大于1毫米的水滴已经相对于重力使用了; 小于1W的输入电力。也证明了气溶胶颗粒在空气中的浓度。

49. 发明授权

US09529008B2 Sampling probes, systems, apparatuses, and methods 有权
标题翻译：采样探头，系统，设备和方法
公开(公告)号：US09529008B2
公开(公告)日：2016-12-27
申请号：US13411337
申请日：2012-03-02
申请人： Wesley Smith , Glen Davis , John Jackson , Gregory Kaduchak , Michael Ward
发明人： Wesley Smith , Glen Davis , John Jackson , Gregory Kaduchak , Michael Ward
IPC分类号： G01N1/10 , G01N35/10
CPC分类号： G01N35/1011 , G01N15/1404 , G01N35/0099
摘要： A sampling system is provided. The sampling system includes a housing. Mounted to the housing is a Hall effect sensor. A probe configured to contact a sample is inserted into the housing. The probe includes an elongated portion and a restorative spring inserted onto the elongated portion of the probe. The restorative spring provides sufficient restorative force to return the probe to a relaxed position. The Hall effect sensor is configured to sense a field strength generated by the proximity of the restorative spring of the probe in the extended position.
摘要翻译：提供采样系统。采样系统包括壳体。安装到外壳是霍尔效应传感器。被配置成接触样品的探针被插入壳体中。探针包括细长部分和插入到探针的细长部分上的修复弹簧。修复弹簧提供足够的修复力以将探头返回到松弛位置。霍尔效应传感器被配置为感测由延伸位置处的探头的修复弹簧附近产生的场强。

50. 发明授权

US09457139B2 Kits for systems and methods using acoustic radiation pressure 有权
标题翻译：使用声辐射压力的系统和方法的套件
公开(公告)号：US09457139B2
公开(公告)日：2016-10-04
申请号：US12239501
申请日：2008-09-26
申请人： Michael D. Ward , John W. Elling , Gregory Kaduchak
发明人： Michael D. Ward , John W. Elling , Gregory Kaduchak
IPC分类号： A61M1/36 , G01N15/12 , G01N27/447 , G01N21/64 , G01N15/14 , G01N29/22 , G01N21/17
CPC分类号： G01N15/1404 , A61M1/3678 , G01N15/12 , G01N15/147 , G01N21/1702 , G01N21/64 , G01N21/6428 , G01N21/645 , G01N27/447 , G01N29/222 , G01N33/56966 , G01N2015/1409 , G01N2015/1415 , G01N2015/142 , G01N2291/02416 , G01N2291/02809 , G01N2291/02836 , Y10T436/101666 , Y10T436/25 , Y10T436/25375 , Y10T436/25625 , Y10T436/2575
摘要： A kit for reagents for use in an acoustic apparatus includes a first fluid that is a lysis fluid, a second fluid having an acoustic contrast that is greater than that of the first fluid, and a reagent for labeling a particle.
摘要翻译：用于声学设备的用于试剂的试剂盒包括作为裂解液的第一流体，具有大于第一流体的声学对比度的第二流体和用于标记颗粒的试剂。

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