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41. 发明专利

ES2784369T3 Uso de laminina 2 para el diagnóstico de carcinoma hepatocelular y cáncer de páncreas 未知
公开(公告)号：ES2784369T3
公开(公告)日：2020-09-24
申请号：ES16788569
申请日：2016-09-28
申请人： ABBOTT JAPAN CO LTD , UNIV TOKYO
发明人： YOSHIMURA TORU , YOSHIDA EISAKU , KOSHIKAWA NAOHIKO , SEIKI MOTOHARU
IPC分类号： G01N33/574
摘要： Un método para diagnosticar carcinoma hepatocelular (HCC) en un sujeto con necesidad de ello, el método comprendiendo: (a) determinar los niveles de monómero de laminina gamma 2 y uno o ambos de antagonista-II de vitamina K inducido por proteínas (PIVKA-II) y alfa fetoproteína (AFP) en una muestra biológica obtenida del sujeto; (b) comparar el nivel de monómero de laminina gamma 2 y uno o ambos de antagonista-II de vitamina K inducido por proteínas (PIVKA-II) y alfa fetoproteína (AFP) con niveles de referencia de monómero de laminina gamma 2, PIVKA-II y/o AFP; y (c) identificar que el sujeto tiene HCC cuando los niveles de monómero de laminina gamma 2 y uno o ambos de PIVKA-II y AFP son mayores que los niveles de referencia de monómero de laminina gamma 2, PIVKA-II y/o AFP, respectivamente.

42. 发明专利

HK1259001A1 癌症的預後和診斷方法未知
公开(公告)号：HK1259001A1
公开(公告)日：2019-11-22
申请号：HK19101487
申请日：2019-01-29
申请人： ABBOTT JAPAN CO LTD , UNIV TOKYO
发明人： NAOHIKO KOSHIKAWA , MASATOSHI NAKAGAWA , EISAKU YOSHIDA , TORU YOSHIMURA , MOTOHARU SEIKI
IPC分类号： G01N20060101

43. 发明专利

HK1211345A1 METHODS OF PROGNOSIS AND DIAGNOSIS OF CANCER 未知
公开(公告)号：HK1211345A1
公开(公告)日：2016-05-20
申请号：HK15112178
申请日：2015-12-10
申请人： ABBOTT JAPAN CO LTD , UNIV TOKYO
发明人： KOSHIKAWA NAOHIKO , NAKAGAWA MASATOSHI , YOSHIDA EISAKU , YOSHIMURA TORU , SEIKI MOTOHARU
IPC分类号： G01N20060101
摘要： Provided are methods of diagnosing cancer in a patient by detecting the presence and/or amount of a biomarker of cancer in a sample from the patient. The methods and biomarkers may be used to develop an accurate prognosis for a patient having cancer or suspected of having cancer, or to accurately diagnose a patient having, or suspected of having cancer. The methods and biomarkers may be used to identify and/or classify a patient as a candidate for a cancer therapy.

44. 发明专利

ES2246062T3 PREPARACION DEL TIPO DE ABSORCION PERCUTANEA QUE CONTIENE TULOBUTEROL. 未知
公开(公告)号：ES2246062T3
公开(公告)日：2006-02-01
申请号：ES98123314
申请日：1998-12-08
申请人： NITTO DENKO CORP , ABBOTT JAPAN CO LTD
发明人： NAKANO YOSHIHISA , HORI MITSUHIKO , YAMAMOTO KEIJI , OTSUKA SABURO
IPC分类号： A61K9/70 , A61K31/00 , A61K31/045 , A61K31/135 , A61P11/00 , A61P11/08
摘要： SE DESCRIBE UNA PREPARACION DEL TIPO DE ABSORCION PERCUTANEA, QUE COMPRENDE UN SOPORTE Y UNA CAPA DE YESO LAMINADA SOBRE EL MISMO, QUE INCLUYE TULOBUTEROL EN UNA PROPORCION NO INFERIOR AL 5% EN PESO, EN ESTADO DE DISOLUCION, Y UN ADHESIVO. LA PREPARACION DE LA PRESENTE INVENCION RETIENE EL INGREDIENTE ACTIVO, TULOBUTEROL, A UNA ELEVADA CONCENTRACION EN ESTADO DE DISOLUCION COMPLETA EN LA CAPA DE YESO. EN CONSECUENCIA, ESTA LIBRE DE LOS CAMBIOS A LO LARGO DEL TIEMPO EN CUANTO A SU PROPIEDAD DE LIBERACION DEL FARMACO Y SU PROPIEDAD ADHESIVA PROVOCADA POR LA PRECIPITACION DE LOS CRISTALES DE FARMACO CON EL TRANSCURSO DEL TIEMPO. LA PREPARACION DE LA INVENCION ES SUPERIOR EN ABSORCION PERCUTANEA DEL FARMACO, PARTICULARMENTE LA VELOCIDAD DE ABSORCION PERCUTANEA EN LA ETAPA INICIAL DE LA ADMINISTRACION; MUESTRA UNA DURACION SUPERIOR DE EFICACIA PORQUE MANTIENE DURANTE UN TIEMPO PROLONGADO UNA CONCENTRACION EN SANGRE EFECTIVA; Y VA ASOCIADA A MENOS CAMBIOS CON EL TRANSCURSO DEL TIEMPO EN CUANTO ASUS PROPIEDADES ADHESIVAS, POR EJEMPLO, SU ADHERENCIA A LA PIEL.

45. 发明专利

HK1025385A1 Immunoassay apparatus 未知
公开(公告)号：HK1025385A1
公开(公告)日：2000-11-10
申请号：HK00104397
申请日：2000-07-18
申请人： ABBOTT JAPAN CO LTD
发明人： NAKAYA MIHO , CHIBA RYOTARO
IPC分类号： G01N20060101 , G01N33/543 , C12M1/34 , G01N33/558
摘要： An immunoassay device which comprises a Chromatography strip having a substrate adhered to the under surface thereof and a protective laminate adhered to the top surface thereof, wherein a space is arranged on the top and/or under surface of at least a partial region of a coloring region of the chromatography strip. The immunoassay device can perform uniform capillary flow of sample solution in the coloring region of a chromatography strip of the immunoassay device and therefore has high detection accuracy.

46. 发明专利

PT922453E PREPARACAO DO TIPO DE ABSORCAO PERCUTANEA CONTENDO TULOBUTEROL 未知
公开(公告)号：PT922453E
公开(公告)日：2005-11-30
申请号：PT98123314
申请日：1998-12-08
申请人： NITTO DENKO CORP , ABBOTT JAPAN CO LTD
发明人： OTSUKA SABURO , YOSHIHISA NAKANO , MITSUHIKO HORI , KEIJI YAMAMOTO
IPC分类号： A61K9/70 , A61K31/00 , A61K31/045 , A61K31/135 , A61P11/00 , A61P11/08

47. 发明专利

AU3309793A AN AMPHOTERIC TRICYCLIC COMPOUND 未知
公开(公告)号：AU3309793A
公开(公告)日：1993-08-26
申请号：AU3309793
申请日：1993-02-17
申请人： ABBOTT JAPAN CO LTD
发明人： YASUO ITO , HIDEO KATO , SHINGO YASUDA , NORIYUKI KADO , NOBUHIKO IWASAKI , HIROYUKI NISHINO , MAKOTO TAKESHITA
IPC分类号： A61K31/445 , A61K31/00 , A61K31/4465 , A61K31/4523 , A61K31/4545 , A61K31/55 , A61P11/00 , A61P17/00 , A61P27/16 , A61P37/00 , A61P37/08 , A61P43/00 , C07D491/04 , C07D491/044 , C07D491/052

48. 发明专利

JP2014062760A Specimen automatic conveyance system performing allocation of specimen between plural analyzers capable of simultaneously measuring multi-item, and method thereof 审中-公开
标题翻译：标准自动输送系统执行能够同时测量多项目的多个分析仪之间的样本分配及其方法
公开(公告)号：JP2014062760A
公开(公告)日：2014-04-10
申请号：JP2012206756
申请日：2012-09-20
申请人： Abbott Japan Co Ltd , アボットジャパン株式会社
发明人： KANEHIRO MASAHIKO , MORI MASAYUKI
IPC分类号： G01N35/00
摘要： PROBLEM TO BE SOLVED: To provide a specimen automatic conveyance system capable of efficiently performing allocation.SOLUTION: A specimen automatic conveyance system confirms a measurement item of a specimen, determines the processing capacity of an analyzer at that time for each of plural analyzers, and allocates the confirmed measurement item of the specimen to an analyzer according to the processing capacity of the analyzer at that time. For example, the processing capacity of an analyzer at that time is based on the number of accumulative correction measurements of the analyzer at that time.
摘要翻译：要解决的问题：提供能够有效地执行分配的样本自动传送系统。解决方案：样本自动传送系统确认样本的测量项目，确定多个分析器中的每个分析器的处理能力，以及根据分析仪当时的处理能力，将分析仪的确认测定项目分配给分析仪。例如，此时分析仪的处理能力是基于当时分析仪的累积校正测量次数。

49. 发明专利

JP2011098133A Self-injection aid and self-injection system 有权
标题翻译：自动注射和自动注射系统
公开(公告)号：JP2011098133A
公开(公告)日：2011-05-19
申请号：JP2009255715
申请日：2009-11-09
申请人： Abbott Japan Co Ltd , アボットジャパン株式会社
发明人： ITAKURA ATSUSHI , MOROI NORIKO
IPC分类号： A61M5/32 , A61M5/178
摘要： PROBLEM TO BE SOLVED: To provide a self-injection aid which has a simple operation to remove a needle cap from a syringe, prevents a cover from being opened in the middle of the self-injection, mitigates the resistance of a patient to the self-injection, and allowing him/her to confirm the syringe while the cover is closed. SOLUTION: The self-injection aid for assisting the self-injection to allow the patient him/herself to inject a therapeutic medicine filled inside the syringe includes: a body for fixing the syringe; and a transparent cover to be openable/closable with respect to the body. When the syringe is fixed to the body at a correct position, the cover is closed and locked with respect to the body. The self injection aid also includes: a needle cap removal mechanism for removing the needle cap of the syringe; and an operation mechanism to operate the needle cap removal mechanism in accordance with the closing operation of the cover with respect to the body. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：为了提供一种自动注射辅助装置，其具有从注射器去除针帽的简单操作，防止了在自身注射中间的盖子被打开，从而减轻了患者的阻力自动注射，并允许他/她在盖子关闭时确认注射器。解决方案：用于辅助自身注射以允许患者自己注射填充在注射器内部的治疗药物的自身注射助剂包括：用于固定注射器的主体; 以及相对于身体可打开/关闭的透明盖。当注射器在正确的位置固定到身体时，盖子相对于身体被封闭并锁定。自身注射辅助装置还包括：用于去除注射器的针帽的针头盖移除机构; 以及根据盖相对于身体的关闭操作来操作针帽移除机构的操作机构。版权所有（C）2011，JPO＆INPIT

50. 发明专利

JP2008290964A Antibody-antibody conjugate and application to antibody-determining diagnostic agent 有权
标题翻译：抗体抗体结合和应用于抗体测定诊断代理
公开(公告)号：JP2008290964A
公开(公告)日：2008-12-04
申请号：JP2007137603
申请日：2007-05-24
申请人： Abbott Japan Co Ltd , アボットジャパン株式会社
发明人： TAKEDA KATSUMICHI , YOSHIDA EISAKU
IPC分类号： C07K16/46 , C07K16/08 , G01N33/569
摘要： PROBLEM TO BE SOLVED: To develop a substitute for an antigen-specific human immunoglobulin which is a positive control or a calibrator indispensable for the evaluation of the measured result in a system for measuring an antigen-specific human immunoglobulin and difficult to stably acquire.
SOLUTION: The chemical conjugation of a plurality of kinds of antibodies (immunoglobulins) provides an artificial antibody having the plurality of properties. For example, the chemical conjugation of anti-parvovirus B19 mouse IgG antibody and human IgM antibody gives an artificial antibody recognizing parvovirus B19 antigen and having the property of human IgM and the product is useful as a positive control or a calibrator used in a method for measuring anti-parvovirus B19 antigen human IgM antibody.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：待解决的问题：开发一种抗原特异性人免疫球蛋白的替代物，该抗原特异性人免疫球蛋白是用于测定抗原特异性人免疫球蛋白的测定系统中难以稳定的测定结果所必需的阳性对照或校准物获得。解决方案：多种抗体（免疫球蛋白）的化学共轭提供具有多种性质的人造抗体。例如，抗细小病毒B19小鼠IgG抗体和人IgM抗体的化学偶联产生识别细小病毒B19抗原并具有人IgM性质的人造抗体，并且该产物可用作阳性对照或用于方法测量抗细小病毒B19抗原人IgM抗体。版权所有（C）2009，JPO＆INPIT

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