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    • 32. 发明申请
    • Apparatuses and methods for assaying analytes using photoelectrochemical labels
    • 使用光电化学标记分析分析物的装置和方法
    • US20060148102A1
    • 2006-07-06
    • US10535905
    • 2003-05-06
    • Lianghong GuoDong DongDong ZhengFuquan WangXiqiang YangJing Cheng
    • Lianghong GuoDong DongDong ZhengFuquan WangXiqiang YangJing Cheng
    • G01N33/551
    • G01N33/582C12Q1/6816G01N2458/30C12Q2563/113C12Q2523/313
    • The present invention provides apparatus, kits and methods for assaying analytes using photoelectrochemical molecules as labels. Specifically, the present invention provides a method for assaying an analyte, comprising: a) contacting a sample suspected of containing an analyte with a reactant capable of binding and/or reacting with the analyte under suitable conditions to allow binding of analyte, if present in the sample, to the reactant; and b) assessing binding and/or reacting between the analyte and the reactant to determine presence and/or amount of analyte in the sample, wherein the reactant, analyte, or additional reactant or additional analyte or analyte analog is labeled with a photoelectrochemically active molecule. The assessing step also comprises converting the photoelectrochemically active molecule with light to an excited state in the presence of an electrode, and assessing an electric current generated by an electron transfer between the excited photoelectrochemically active molecule and the electrode.
    • 本发明提供了使用光电化学分子作为标记来测定分析物的装置,试剂盒和方法。 具体地,本发明提供了一种用于分析分析物的方法,其包括:a)在合适的条件下将疑似含有分析物的样品与能够与分析物结合和/或反应的反应物接触,以使分析物(如果存在于 样品,反应物; 和b)评估分析物和反应物之间的结合和/或反应以确定样品中分析物的存在和/或量,其中反应物,分析物或附加反应物或其他分析物或分析物类似物用光电化学活性分子标记 。 评估步骤还包括在电极存在下将光电化学活性分子与光转化为激发态,并评估由激发的光电化学活性分子和电极之间的电子转移产生的电流。
    • 38. 发明授权
    • Process for preparing porous polymer particles
    • 制备多孔聚合物颗粒的方法
    • US08466206B1
    • 2013-06-18
    • US13334199
    • 2011-12-22
    • Xiqiang YangJames R. Bennett
    • Xiqiang YangJames R. Bennett
    • C08J9/00
    • C08J9/0066C08J9/28C08J2201/0482C08J2325/14C08J2367/00
    • A process for forming polymer particles with aligned pores and controlled narrow particle size distribution, including: a) forming an oil phase by dissolving a polymeric binder in a solvent; b) dispersing the oil phase into a water phase containing a controlled amount of particulate stabilizer and forming an oil-in-water emulsion of controlled narrow dispersed oil phase droplet size distribution; c) freezing the emulsion to freeze solvent in the oil droplets to form frozen solvent domains within the polymeric binder, and also the water in the continuous water phase; and d) removing the frozen solvent from the polymeric binder and the frozen water in the continuous water phase, thereby forming porous polymer particles of controlled narrow particle size distribution and containing directional aligned non-spherical pore structures. Optionally, the porous particles may contain encapsulated functional ingredients.
    • 一种用于形成具有排列孔和受控的窄粒度分布的聚合物颗粒的方法,包括:a)通过将聚合物粘合剂溶解在溶剂中形成油相; b)将油相分散到含有受控量的颗粒稳定剂的水相中并形成受控窄分散油相液滴尺寸分布的水包油乳液; c)冷冻乳液以在油滴中冷冻溶剂,以在聚合物粘合剂内形成冷冻溶剂结构域,以及连续水相中的水; 以及d)从连续水相中的聚合物粘合剂和冷冻水中除去冷冻的溶剂,从而形成受控窄粒度分布的多孔聚合物颗粒并且包含定向排列的非球形孔结构。 任选地,多孔颗粒可以含有包封的功能性成分。
    • 39. 发明授权
    • Method of preparing toner having controlled morphology
    • 制备具有受控形态的调色剂的方法
    • US08137888B2
    • 2012-03-20
    • US12342138
    • 2008-12-23
    • Xiqiang Yang
    • Xiqiang Yang
    • G03G9/087
    • G03G9/0804C08J3/16G03G9/0827G03G9/08755
    • A method for the preparation of shaped polymeric particles, and in a particular embodiment shaped electrostatographic toner particles, of controlled morphology including the following steps. A selected solvent or solvent mixture is used to dissolve a polyester polymer material to form an organic phase, wherein the polyester material is formed from at least one diol and at least one multicarboxylic aromatic acid and has a solubility parameter of greater than 9.0 (cal/cm3)1/2, the selected solvent or solvent mixture includes at least a first solvent having a solubility parameter of less than 9.0 (cal/cm3)1/2, and the difference in solubility parameters for the polyester material and the at least first solvent is between 1.0 and 3.0 (cal/cm3)1/2. The organic phase is dispersed in an aqueous phase containing a particulate stabilizer to form a dispersion, which is then homogenized. The organic solvent is evaporated from the dispersion to form shaped polymeric particles, and the resultant product is recovered, washed and dried.
    • 一种用于制备成形聚合物颗粒的方法,并且在特定实施方案中形成具有受控形态的成形的静电调色剂颗粒,包括以下步骤。 使用选择的溶剂或溶剂混合物来溶解聚酯聚合物材料以形成有机相,其中聚酯材料由至少一种二醇和至少一种多元芳族酸形成,并且具有大于9.0的溶解度参数(cal / cm 3)1/2,所选择的溶剂或溶剂混合物至少包括溶解度参数小于9.0(cal / cm 3)1/2的第一溶剂,以及聚酯材料和至少第一溶剂参数的差异 溶剂为1.0-3.0(cal / cm3)1/2。 将有机相分散在含有颗粒稳定剂的水相中以形成分散体,然后将其均化。 从分散体蒸发有机溶剂以形成成型的聚合物颗粒,并将所得产物回收,洗涤和干燥。