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31. 发明授权

US4432990A 5-Aminoimidazoles as immunoregulants 失效
标题翻译： 5-氨基咪唑作为免疫调节剂
公开(公告)号：US4432990A
公开(公告)日：1984-02-21
申请号：US377125
申请日：1982-05-11
申请人： David Robinson
发明人： David Robinson
IPC分类号： A61K31/415 , A61P35/00 , A61P37/00 , C07D233/88 , C07D233/90
CPC分类号： C07D233/90 , Y10S514/885 , Y10S514/908
摘要： There are described compounds of formula I ##STR1## in which X is --CN, --CONH.sub.2, --CSNH.sub.2, ##STR2## or --CO.sub.2 R.sub.3, R is H or alkyl C 1 to 8,R.sub.1 and R.sub.3, which may be the same or different, are each alkyl C 1 to 8, andR.sub.2 is H or alkanoyl C 2 to 8,and the pharmaceutically acceptable acid addition salts thereof.There are also described processes for producing the compounds, and pharmaceutical, e.g. immunoregulant, compositions containing them.
摘要翻译：描述了式I的化合物，其中X是-CN，-CONH 2，-CSNH 2，或者-CO 2 R 3，R是H或C 1至8的烷基，R 1和R 3可以相同或不同的是各自为C 1至8的烷基，R 2为H或C 2至8的烷酰基，及其药学上可接受的酸加成盐。还描述了用于生产化合物的方法，以及药物，例如，免疫调节剂，含有它们的组合物。

32. 发明授权

US10194992B2 Indicator for knife location in a stapling or vessel sealing instrument 有权
公开(公告)号：US10194992B2
公开(公告)日：2019-02-05
申请号：US13350522
申请日：2012-01-13
申请人： David Robinson
发明人： David Robinson
IPC分类号： A61B34/20 , A61B34/30 , A61B18/14 , A61B17/00 , A61B17/072 , A61B90/98 , A61B90/00
摘要： Systems and methods are provided for displaying an image of a tracked tool on a user interface, wherein at least a portion of the tool is hidden from view in any image on a user interface at any point during a procedure. The tool may include a cutting tool having jaws for clamping a material and a knife for cutting the clamped material, and superimposing an indicator of a knife position on the display during and/or after cutting. The knife position may include a location and/or orientation of the knife, including any or all of a pre-cut, cut-complete, cut-incomplete and an exposed position. The disclosed systems and methods allows a user to view the knife position in applications where the knife may not be visible to a user, which is particularly useful for clamping and cutting a body tissue with a robotic surgical system in minimally invasive procedures.

33. 发明授权

US09219883B2 Controlling placeshifted content 有权
标题翻译：控制放置的内容
公开(公告)号：US09219883B2
公开(公告)日：2015-12-22
申请号：US13397243
申请日：2012-02-15
申请人： David Robinson , Robert Wadey
发明人： David Robinson , Robert Wadey
IPC分类号： H04N7/18 , H04N7/16
CPC分类号： H04N7/16 , H04N21/2407 , H04N21/25435 , H04N21/4227 , H04N21/4623 , H04N21/4882 , H04N21/6106 , H04N21/6156 , H04N21/6581 , H04N21/8355 , H04N21/8358
摘要： Media content to be place shifted is received at the local user device along with a place shift enabled parameter that contains data associated with the received media content and that indicates whether the received media content is authorized to be place shifted. A user command to place shift the received media content to the remote user device is also received. It is then determined, by analyzing the place shift enabled parameter, whether the received media content is authorized to be place shifted and based on this determination the place shifting of the received content to a remote device is allowed or impaired.
摘要翻译：在本地用户设备处接收要移位的媒体内容以及包含与所接收的媒体内容相关联的数据并且指示所接收的媒体内容是否被授权进行移位的启用移位参数。还接收用于将接收的媒体内容移位到远程用户设备的用户命令。然后，通过分析启用了移位功能的参数，确定接收到的媒体内容是否被授权进行移位，并且基于该确定，允许或减少接收的内容向远程设备的移位。

34. 发明授权

US09089714B2 Stitched components of an active implantable medical device 有权
标题翻译：有源可植入医疗器械的缝合部件
公开(公告)号：US09089714B2
公开(公告)日：2015-07-28
申请号：US12549831
申请日：2009-08-28
申请人： David Robinson
发明人： David Robinson
IPC分类号： A61N1/05 , A61N1/375 , H05K3/10 , A61N1/36 , A61N1/372
CPC分类号： A61N1/375 , A61B2562/125 , A61N1/0551 , A61N1/3605 , A61N1/37229 , H05K3/103 , H05K2201/0129 , H05K2201/0281 , H05K2201/0308 , H05K2201/10287 , H05K2201/10598 , H05K2203/1189 , Y10T29/4913
摘要： An active implantable medical device (AIMD) comprising an implantable electronics module and a tissue interface. At least one of the electronics module and the tissue interface comprises an electrically non-conductive, biocompatible and needle-piercable base having one or more biocompatible electrically conductive strands of conductive filaments stitched to the base. As used herein, stitching a conductive filament to a base refers to sewing, embroidering or otherwise securing the filament to the base through the use of hand or machine needlework.
摘要翻译：一种包括可植入电子模块和组织界面的主动植入式医疗装置（AIMD）。电子模块和组织界面中的至少一个包括具有一个或多个与基底缝合的导电丝的一个或多个生物相容的导电股线的非导电，生物相容性和针刺的基底。如本文所使用的，将导电丝缝合到基部是指通过使用手或机针刺将缝线，刺绣或以其他方式将灯丝固定到基座。

35. 发明授权

US08897888B2 Knitted electrode assembly and integrated connector for an active implantable medical device 有权
标题翻译：用于有源植入式医疗器械的针织电极组件和集成连接器
公开(公告)号：US08897888B2
公开(公告)日：2014-11-25
申请号：US12549457
申请日：2009-08-28
申请人： John L. Parker , David Robinson
发明人： John L. Parker , David Robinson
IPC分类号： A61N1/05 , A61M25/00 , A61N1/375
CPC分类号： A61N1/05 , A61M25/0009 , A61N1/0472 , A61N1/0484 , A61N1/0529 , A61N1/375
摘要： An active implantable medical device (AIMD). The AIMD comprises: a knitted electrode assembly comprising: at least one biocompatible, electrically non-conductive filament arranged in substantially parallel rows each stitched to an adjacent row, and at least one biocompatible, electrically conductive filament having a first end intertwined with a first row of the at least one non-conductive filament, and a second end intertwined with a second row of the at least one non-conductive filament, wherein the first and second rows are spaced from one another.
摘要翻译：主动植入医疗器械（AIMD）。 AIMD包括：编织电极组件，其包括：至少一个生物相容的，不导电的细丝，其布置成大致平行的行，每个行缝合到相邻排，以及至少一个生物相容的导电细丝，其具有缠绕在第一排的所述至少一个非导电细丝，以及与所述至少一个非导电细丝的第二排缠绕的第二端，其中所述第一和第二行彼此间隔开。

36. 发明授权

US08638057B2 Selective additional control in a control console for surgical instruments 有权
标题翻译：手术器械控制台中的选择性附加控制
公开(公告)号：US08638057B2
公开(公告)日：2014-01-28
申请号：US13356989
申请日：2012-01-24
申请人： Randal P. Goldberg , Michael Hanuschik , Paul Millman , John W. Zabinski , David Robinson , Paul W. Mohr , Thomas R. Nixon , David W. Bailey
发明人： Randal P. Goldberg , Michael Hanuschik , Paul Millman , John W. Zabinski , David Robinson , Paul W. Mohr , Thomas R. Nixon , David W. Bailey
IPC分类号： B64C13/20
CPC分类号： A61B34/30 , A61B34/25 , A61B34/37 , A61B90/361 , A61B2017/00477 , A61B2017/00973 , Y10T74/20
摘要： A control console to remotely control medical equipment is disclosed having a base with an ergonomically adjustable pedal system. The base further has an opening to receive the pedal system. The pedal system includes a moveable pedal tray with a pedal base. The tray includes a first left pedal assembly and a first right pedal assembly, and an upper tier having a second left pedal assembly and a second right pedal assembly respectively in alignment with and elevated above the first left pedal assembly and the first right pedal assembly. Rollers are rotatable coupled to the moveable pedal tray to allow it roll over a floor. A drive assembly is coupled between the moveable pedal tray and the base. The drive assembly applies a force to the to roll the moveable pedal tray over the floor within the opening of the base.
摘要翻译：公开了一种用于遥控医疗设备的控制台，具有具有人体工程学可调节踏板系统的基座。基座还具有接收踏板系统的开口。踏板系统包括具有踏板底座的可动踏板盘。托盘包括第一左踏板组件和第一右踏板组件，以及上层，其具有分别与第一左踏板组件和第一右踏板组件对准并升高的第二左踏板组件和第二右踏板组件。辊可旋转地联接到可移动的踏板盘，以允许其在地板上滚动。驱动组件联接在可动踏板盘和基座之间。驱动组件向基座的开口内的地板上施加力以将可动踏板托盘滚动。

37. 发明申请

US20130031374A1 FIRMWARE-BASED TRUSTED PLATFORM MODULE FOR ARM PROCESSOR ARCHITECTURES AND TRUSTZONE SECURITY EXTENSIONS 有权
标题翻译：用于ARM处理器架构和TRUSTZONE安全扩展的基于固件的TRUSTED平台模块
公开(公告)号：US20130031374A1
公开(公告)日：2013-01-31
申请号：US13193945
申请日：2011-07-29
申请人： Stefan Thom , Jeremiah Cox , David Linsley , Magnus Nystrom , Himanshu Raj , David Robinson , Stefan Saroiu , Rob Spiger , Alastair Wolman
发明人： Stefan Thom , Jeremiah Cox , David Linsley , Magnus Nystrom , Himanshu Raj , David Robinson , Stefan Saroiu , Rob Spiger , Alastair Wolman
IPC分类号： G06F21/00
CPC分类号： G06F21/552 , G06F21/46 , G06F21/57 , G06F21/572 , G06F21/575 , G06F21/71 , G06F21/74 , G06F2221/034
摘要： A “Firmware-Based TPM” or “fTPM” ensures that secure code execution is isolated to prevent a wide variety of potential security breaches. Unlike a conventional hardware based Trusted Platform Module (TPM), isolation is achieved without the use of dedicated security processor hardware or silicon. In general, the fTPM is first instantiated in a pre-OS boot environment by reading the fTPM from system firmware or firmware accessible memory or storage and placed into read-only protected memory of the device. Once instantiated, the fTPM enables execution isolation for ensuring secure code execution. More specifically, the fTPM is placed into protected read-only memory to enable the device to use hardware such as the ARM® architecture's TrustZone™ extensions and security primitives (or similar processor architectures), and thus the devices based on such architectures, to provide secure execution isolation within a “firmware-based TPM” without requiring hardware modifications to existing devices.
摘要翻译：基于固件的TPM或fTPM确保安全代码执行被隔离，以防止各种潜在的安全漏洞。与传统的基于硬件的可信平台模块（TPM）不同，在不使用专用安全处理器硬件或硅片的情况下实现隔离。通常，通过从系统固件或固件可访问的存储器或存储器读取fTPM并将其放置在设备的只读受保护的存储器中，fTPM首先在前OS引导环境中实例化。一旦实例化，fTPM就能实现执行隔离，以确保执行安全的代码。更具体地说，将fTPM放置到受保护的只读存储器中，以使设备能够使用诸如ARM®架构的TrustZone™扩展和安全原语（或类似的处理器架构）之类的硬件，从而使基于这种架构的设备提供基于固件的TPM中的安全执行隔离，而不需要对现有设备进行硬件修改。

38. 发明申请

US20120319319A1 FORMING FEEDTHROUGHS FOR HERMETICALLY SEALED HOUSINGS USING TWO-MATERIAL POWDER INJECTION MOLDING 有权
标题翻译：使用两种粉末注射成型制成的密封外壳的成型工艺
公开(公告)号：US20120319319A1
公开(公告)日：2012-12-20
申请号：US13512172
申请日：2010-11-26
申请人： John L. Parker , David Robinson , David Thomas , Mark Fretz
发明人： John L. Parker , David Robinson , David Thomas , Mark Fretz
IPC分类号： B29C45/16
CPC分类号： A61N1/3754 , A61N1/3756 , B22F3/225 , B28B1/24 , B29C33/302 , B29C45/0001 , C04B2111/00137 , C04B2235/6022
摘要： Methods of forming a feedthrough using a mold that defines a cavity when closed and includes one or more cores configured to move in and out of the mold cavity. The methods include injecting non-electrically conductive powder injection molding (PIM) feedstock into the mold cavity to form an insulative body around a portion of each of the cores disposed in the mold cavity, removing each of the cores from the insulative body to form one or more core cavities in the insulative body, injecting electrically conductive PIM feedstock into the core cavities to form one or more conductors in the core cavities, respectively, and sintering the insulative body and the conductors to form the feedthrough.
摘要翻译：使用模具形成馈通的方法，所述模具在关闭时限定空腔，并且包括配置成移入和移出模腔的一个或多个芯体。所述方法包括将非导电粉末注射成型（PIM）原料注入到模腔中以在设置在模腔中的每个芯的一部分周围形成绝缘体，从绝缘体去除每个芯以形成一个或更多个芯腔，分别将导电PIM原料注入到芯腔中以在芯腔中形成一个或多个导体，并且烧结绝缘体和导体以形成馈通。

39. 发明申请

US20120209314A1 Methods and Systems for Indicating a Clamping Prediction 有权
标题翻译：用于指示夹紧预测的方法和系统
公开(公告)号：US20120209314A1
公开(公告)日：2012-08-16
申请号：US13350502
申请日：2012-01-13
申请人： David Weir , Grant Duque , Kevin Durant , Patrick Flanagan , Maggie Nixon , David Robinson , John Zabinski
发明人： David Weir , Grant Duque , Kevin Durant , Patrick Flanagan , Maggie Nixon , David Robinson , John Zabinski
IPC分类号： A61B17/28
CPC分类号： A61B34/25 , A61B17/00 , A61B17/07207 , A61B17/28 , A61B17/29 , A61B34/30 , A61B34/37 , A61B90/06 , A61B90/08 , A61B2017/00115 , A61B2017/00132 , A61B2017/2808 , A61B2034/254 , A61B2034/301 , A61B2090/064 , A61B2090/0811 , B25J9/1694 , G06F3/016 , G06F3/14 , G06F3/16
摘要： End effectors with closing mechanisms, and related tools and methods are disclosed. The disclosed end effectors may be particularly beneficial when used for minimally invasive surgery. An example surgical tool comprises a first and second jaw movable between a closed grasped or clamped configuration and an open configuration. The tool further comprises a soft grip mode for grasping the tissue at a first force during which a separation parameter between the jaws is measured, and a therapeutic clamping mode in which the jaws clamp on the body tissue at a force greater than the grasping force. The methods comprise grasping the body tissue between jaw members, measuring the separation parameter between jaws, indicating on a user interface the separation parameter for comparison to a desired separation parameter, and then releasing the body tissue for repositioning or therapeutically clamping the body tissue in response to the separation parameter indication.
摘要翻译：具有关闭机构的结束执行器以及相关的工具和方法被公开。所公开的末端效应器在用于微创手术时可能是特别有益的。一种示例性外科手术工具包括可在关闭的被抓握或夹紧构型和打开构型之间移动的第一和第二钳口。该工具进一步包括用于在第一力处抓住组织的软抓握模式，在该第一力期间测量夹爪之间的分离参数，以及治疗夹紧模式，其中夹爪以大于抓握力的力夹紧在身体组织上。所述方法包括抓住钳口构件之间的身体组织，测量钳口之间的分离参数，在用户界面上指示分离参数以与期望的分离参数进行比较，然后释放身体组织以重新定位或治疗性地夹紧身体组织以作出响应到分离参数指示。

40. 发明申请

US20120209288A1 Indicator for Knife Location in a Stapling or Vessel Sealing Instrument 审中-公开
标题翻译：刀具位置指示器在装订或容器密封仪器中
公开(公告)号：US20120209288A1
公开(公告)日：2012-08-16
申请号：US13350522
申请日：2012-01-13
申请人： David Robinson
发明人： David Robinson
IPC分类号： A61B19/00
CPC分类号： A61B34/20 , A61B18/14 , A61B18/1445 , A61B34/30 , A61B90/98 , A61B2017/00022 , A61B2017/00398 , A61B2017/07285 , A61B2018/1455 , A61B2034/2051 , A61B2034/2059 , A61B2090/0803
摘要： Systems and methods are provided for displaying an image of a tracked tool on a user interface, wherein at least a portion of the tool is hidden from view in any image on a user interface at any point during a procedure. The tool may include a cutting tool having jaws for clamping a material and a knife for cutting the clamped material, and superimposing an indicator of a knife position on the display during and/or after cutting. The knife position may include a location and/or orientation of the knife, including any or all of a pre-cut, cut-complete, cut-incomplete and an exposed position. The disclosed systems and methods allows a user to view the knife position in applications where the knife may not be visible to a user, which is particularly useful for clamping and cutting a body tissue with a robotic surgical system in minimally invasive procedures.
摘要翻译：提供了用于在用户界面上显示被跟踪工具的图像的系统和方法，其中在过程期间的任何时刻，在用户界面上的任何图像中，工具的至少一部分被隐藏在视图中。该工具可以包括具有用于夹紧材料的夹爪和用于切割被夹紧材料的刀的切割工具，以及在切割期间和/或之后将刀位置的指示器叠加在显示器上。刀位置可以包括刀的位置和/或取向，包括预切割，切割完成，切割不完全和暴露位置中的任何一个或全部。所公开的系统和方法允许用户在用户不可见的应用中观察刀位置，这对于在微创程序中用机器人手术系统夹紧和切割身体组织特别有用。

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