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31. 发明授权

US08725258B2 Method and apparatus for automated adjustment of arrhythmia detection duration 有权
标题翻译：用于自动调节心律失常检测持续时间的方法和装置
公开(公告)号：US08725258B2
公开(公告)日：2014-05-13
申请号：US11467421
申请日：2006-08-25
申请人： Dan Li , Shelley Cazares
发明人： Dan Li , Shelley Cazares
IPC分类号： A61N1/362
CPC分类号： A61N1/3624 , A61B5/046 , A61B5/0464 , A61B5/7275 , A61N1/3622 , A61N1/3925 , A61N1/3962 , A61N1/3987
摘要： A cardiac rhythm management (CRM) system delivers anti-tachyarrhythmia therapies and uses patient-specific and/or tachyarrhythmia event-specific information to automatically set and adjust one or more arrhythmia detection durations. In one embodiment, the CRM system initializes and updates the one or more arrhythmia detection durations using patient-specific information such as medical history and recent medical trends. In another embodiment, the CRM dynamically adjusts the one or more arrhythmia detection durations using the patient's hemodynamic performance. One example of such an arrhythmia detection duration is a sustained rate duration (SRD) that starts when a tachyarrhythmia such as a supraventricular tachyarrhythmia is detected. An anti-tachyarrhythmia therapy is delivered only if the tachyarrhythmia sustains throughout the SRD.
摘要翻译：心律管理（CRM）系统提供抗心律失常疗法，并使用患者特异性和/或快速性心律失常事件特定信息来自动设置和调整一种或多种心律失常检测持续时间。在一个实施例中，CRM系统使用患者特定信息（例如病史和最近的医疗趋势）来初始化和更新一个或多个心律失常检测持续时间。在另一个实施例中，CRM使用患者的血液动力学性能来动态地调整一个或多个心律失常检测持续时间。这种心律失常检测持续时间的一个例子是当检测到诸如室上性快速性心律失常之类的快速性心律失常时开始的持续速率持续时间（SRD）。仅在快速性心律失常在整个SRD中持续时才能进行抗快速性心律失常治疗。

32. 发明申请

US20120330381A1 AUTOMATED DEVICE PROGRAMMING AT CHANGEOUT 有权
标题翻译：自动化设备编程更改
公开(公告)号：US20120330381A1
公开(公告)日：2012-12-27
申请号：US13603934
申请日：2012-09-05
申请人： Shelley Cazares , Dan Li , Jonathan Kwok
发明人： Shelley Cazares , Dan Li , Jonathan Kwok
IPC分类号： A61N1/08
CPC分类号： A61B5/0031 , G06F19/00
摘要： This document discusses, among other things, methods and systems for facilitating automated device programming at changeout. A method comprises receiving, from a first device, physiological data at a temporary storage device; and processing the received physiological data, wherein the processing includes determining if a first signal processing function was used by the first device and substantially offsetting the first signal processing function if the first signal processing function was used by the first device; and processing the resultant physiological data to be compatible with a second device. The method further comprising providing the processed resultant physiological data to the second device.
摘要翻译：本文档除了其他内容之外还讨论了用于在切换时实现自动化设备编程的方法和系统。一种方法包括从临时存储装置接收来自第一装置的生理数据; 以及处理所接收的生理数据，其中所述处理包括确定所述第一设备是否使用第一信号处理功能，并且如果所述第一设备使用所述第一信号处理功能，则基本上抵消所述第一信号处理功能; 以及将所生成的生理数据处理为与第二设备兼容。该方法还包括向第二设备提供经处理的合成生理数据。

33. 发明申请

US20100292761A1 AUTOMATED DEVICE PROGRAMMING AT CHANGEOUT 有权
标题翻译：自动化设备编程更改
公开(公告)号：US20100292761A1
公开(公告)日：2010-11-18
申请号：US12839913
申请日：2010-07-20
申请人： Shelley Cazares , Dan Li , Jonathan Kwok
发明人： Shelley Cazares , Dan Li , Jonathan Kwok
IPC分类号： A61N1/08
CPC分类号： A61B5/0031 , G06F19/00
摘要： This document discusses, among other things, methods and systems for facilitating automated device programming at changeout. A method comprises receiving, from a first device, physiological data at a temporary storage device; and processing the received physiological data, wherein the processing includes determining if a first signal processing function was used by the first device and substantially offsetting the first signal processing function if the first signal processing function was used by the first device; and processing the resultant physiological data to be compatible with a second device. The method further comprising providing the processed resultant physiological data to the second device.
摘要翻译：本文档除了其他内容之外还讨论了用于在切换时实现自动化设备编程的方法和系统。一种方法包括从临时存储装置接收来自第一装置的生理数据; 以及处理所接收的生理数据，其中所述处理包括确定所述第一设备是否使用第一信号处理功能，并且如果所述第一设备使用所述第一信号处理功能，则基本上抵消所述第一信号处理功能; 以及将所生成的生理数据处理为与第二设备兼容。该方法还包括向第二设备提供经处理的合成生理数据。

34. 发明授权

US07582061B2 Method and apparatus for morphology-based arrhythmia classification using cardiac and other physiological signals 有权
标题翻译：使用心脏和其他生理信号进行形态学心律失常分类的方法和装置
公开(公告)号：US07582061B2
公开(公告)日：2009-09-01
申请号：US11316332
申请日：2005-12-22
申请人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
发明人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
IPC分类号： A61B5/02
CPC分类号： A61B5/0464 , A61B5/7264 , A61N1/3621 , A61N1/36521 , A61N1/36542 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/36585 , A61N1/3925 , A61N1/3962
摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.
摘要翻译：快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板波形的形态特征之间的相关性的相关系数。通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

35. 发明申请

US20080071182A1 Systems and methods for arranging and labeling cardiac episodes 有权
标题翻译：安排和标记心脏病发作的系统和方法
公开(公告)号：US20080071182A1
公开(公告)日：2008-03-20
申请号：US11643220
申请日：2006-12-21
申请人： Shelley Cazares , Aaron McCabe , Alok Sathaye , Dan Li
发明人： Shelley Cazares , Aaron McCabe , Alok Sathaye , Dan Li
IPC分类号： A61B5/0402
CPC分类号： A61B5/0464 , A61B5/726
摘要： Methods and systems for arranging and labeling cardiac episodes based on acquired cardiac episode data are described. Cardiac episodes are algorithmically arranged based on one or more discriminating features of the episode data. A user is presented with at least one episode selected from the arrangement of cardiac episodes. The user inputs a label that characterizes the selected episode. The label is algorithmically appended to the data of the selected episode and to other episodes of the arrangement of cardiac episodes based on the discriminating features.
摘要翻译：描述了基于获得性心脏病发作数据来安排和标记心脏发作的方法和系统。基于事件数据的一个或多个鉴别特征，算术地布置心脏事件。向用户呈现从心脏发作的排列中选出的至少一个情节。用户输入表征所选剧集的标签。基于鉴别特征，标签被算法地附加到所选事件的数据和心脏发作的安排的其他发作。

36. 发明申请

US20080004500A1 AUTOMATED DEVICE PROGRAMMING AT CHANGEOUT 有权
标题翻译：自动化设备编程更改
公开(公告)号：US20080004500A1
公开(公告)日：2008-01-03
申请号：US11427407
申请日：2006-06-29
申请人： Shelley Cazares , Dan Li , Jonathan Kwok
发明人： Shelley Cazares , Dan Li , Jonathan Kwok
IPC分类号： A61B5/00
CPC分类号： A61B5/0031 , G06F19/00
摘要： This document discusses, among other things, methods and systems for facilitating automated device programming at changeout. A method comprises receiving, from a first device, physiological data at a temporary storage device; and processing the received physiological data, wherein the processing includes determining if a first signal processing function was used by the first device and substantially offsetting the first signal processing function if the first signal processing function was used by the first device; and processing the resultant physiological data to be compatible with a second device. The method further comprising providing the processed resultant physiological data to the second device.
摘要翻译：本文档除了其他内容之外还讨论了用于在切换时实现自动化设备编程的方法和系统。一种方法包括从临时存储装置接收来自第一装置的生理数据; 以及处理所接收的生理数据，其中所述处理包括确定所述第一设备是否使用第一信号处理功能，并且如果所述第一设备使用所述第一信号处理功能，则基本上抵消所述第一信号处理功能; 以及将所生成的生理数据处理为与第二设备兼容。该方法还包括向第二设备提供经处理的合成生理数据。

37. 发明授权

US07783356B2 Automated device programming at changeout 有权
标题翻译：自动化设备编程改变
公开(公告)号：US07783356B2
公开(公告)日：2010-08-24
申请号：US11427407
申请日：2006-06-29
申请人： Shelley Cazares , Dan Li , Jonathan Kwok
发明人： Shelley Cazares , Dan Li , Jonathan Kwok
IPC分类号： A61N1/362
CPC分类号： A61B5/0031 , G06F19/00
摘要： This document discusses, among other things, methods and systems for facilitating automated device programming at changeout. A method comprises receiving, from a first device, physiological data at a temporary storage device; and processing the received physiological data, wherein the processing includes determining if a first signal processing function was used by the first device and substantially offsetting the first signal processing function if the first signal processing function was used by the first device; and processing the resultant physiological data to be compatible with a second device. The method further comprising providing the processed resultant physiological data to the second device.
摘要翻译：本文档除了其他内容之外还讨论了用于在切换时实现自动化设备编程的方法和系统。一种方法包括从临时存储装置接收来自第一装置的生理数据; 以及处理所接收的生理数据，其中所述处理包括确定所述第一设备是否使用第一信号处理功能，并且如果所述第一设备使用所述第一信号处理功能，则基本上抵消所述第一信号处理功能; 以及将所生成的生理数据处理为与第二设备兼容。该方法还包括向第二设备提供经处理的合成生理数据。

38. 发明申请

US20090292332A1 METHOD AND APPARATUS FOR MORPHOLOGY-BASED ARRHYTHMIA CLASSIFICATION USING CARDIAC AND OTHER PHYSIOLOGICAL SIGNALS 有权
标题翻译：使用心脏和其他生理信号进行形态学基于ARRHYTHMIA分类的方法和装置
公开(公告)号：US20090292332A1
公开(公告)日：2009-11-26
申请号：US12536828
申请日：2009-08-06
申请人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
发明人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
IPC分类号： A61N1/39 , A61B5/02 , A61B5/0205
CPC分类号： A61B5/0464 , A61B5/7264 , A61N1/3621 , A61N1/36521 , A61N1/36542 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/36585 , A61N1/3925 , A61N1/3962
摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.
摘要翻译：快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板波形的形态特征之间的相关性的相关系数。通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

39. 发明申请

US20080065165A1 Method and apparatus for identifying potentially misclassified arrhythmic episodes 有权
标题翻译：用于识别潜在错误分类的心律失常发作的方法和装置
公开(公告)号：US20080065165A1
公开(公告)日：2008-03-13
申请号：US11643221
申请日：2006-12-21
申请人： Christopher Dale Johnson , Alok Sathaye , Shelley Cazares
发明人： Christopher Dale Johnson , Alok Sathaye , Shelley Cazares
IPC分类号： A61N1/37
CPC分类号： A61B5/7264 , A61B5/02405 , A61B5/0245 , A61B5/04 , A61B5/04525 , A61B5/0464 , A61B5/6846 , A61B5/726 , A61N1/37247 , G06F19/00 , G06F19/3481
摘要： An implantable cardiac device is configured to classify cardiac arrhythmias using a plurality of arrhythmia discrimination algorithms. Data is provided that is associated with a plurality of cardiac arrhythmic episodes for which a cardiac electrical therapy was delivered or withheld by the implantable medical device based on the plurality of arrhythmia discrimination algorithms. A metric for each of the arrhythmic episodes is computed. The metric defines a measure by which the implantable cardiac device properly classified the arrhythmia. Potentially misclassified arrhythmic episodes of the plurality of cardiac arrhythmic episodes for which cardiac electrical therapy was inappropriately delivered or withheld are algorithmically identified using the metric.
摘要翻译：可植入心脏装置被配置为使用多个心律失常鉴别算法对心律失常进行分类。提供了与多个心律失常发作相关联的数据，根据多种心律不齐判别算法，心脏电疗法由可植入医疗装置递送或保留。计算每个心律失常发作的指标。该度量定义了可植入心脏装置适当分类心律失常的措施。使用度量来算法地识别心电图治疗被不适当地递送或禁止的多个心律失调发作的潜在的错误分类的心律失常发作。

40. 发明申请

US20070239217A1 Cardiac tachy arrhythmia therapy selection based on patient response information 失效
标题翻译：基于患者反应信息的心脏快速心律失常治疗选择
公开(公告)号：US20070239217A1
公开(公告)日：2007-10-11
申请号：US11807696
申请日：2007-05-30
申请人： Shelley Cazares
发明人： Shelley Cazares
IPC分类号： A61N1/00
CPC分类号： A61N1/3925 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61N1/3622 , A61N1/365 , A61N1/3962
摘要： Cardiac treatment methods and devices providing templates representative of past tachyarrhythmia events, each template associated with a therapy. A cardiac waveform is detected, and if it corresponds to a particular template associated with a previous therapy that was satisfactory in terminating a past event, the previous therapy is delivered again. If unsatisfactory, the previous therapy is eliminated as an option. If, for example, the previous therapy was an antitachycardia pacing therapy unsatisfactory in terminating the past tachyarrhythmia event, delivery of the antitachycardia pacing therapy is eliminated as an option. Instead of ATP therapy, one or more of a cardioversion, defibrillation, or alternate anti-tachycardia pacing therapy may be associated with the particular template. Cardiac waveforms and templates may correspond in terms of one or more of morphology, timing, drug regimen, medication, neural activity, patient activity, hemodynamic status, cardiac tissue impedance, transthoracic impedance, or other information corresponding to the episode.
摘要翻译：提供代表过去快速性心律失常事件的模板的心脏治疗方法和装置，每种模板与治疗相关联。检测到心脏波形，并且如果它对应于与先前疗法相关联的特定模板，其在终止过去事件时令人满意，则再次传送先前的治疗。如果不满意，以前的治疗作为一种选择被消除。例如，如果以前的治疗是抗心动过速起搏治疗在终止过去的快速性心律失常事件中不令人满意，则作为选择消除了抗心动过速起搏疗法的输送。代替ATP治疗，可以将一种或多种心脏复律，除颤或替代的抗心动过速起搏治疗与特定模板相关联。心脏波形和模板可以对应于形态，时间，药物方案，药物，神经活动，患者活动，血液动力学状态，心脏组织阻抗，经胸阻抗或对应于该发作的其他信息中的一种或多种。

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