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31. 发明授权

US07115123B2 Handpiece with electrode and non-volatile memory 有权
标题翻译：手机带电极和非易失性存储器
公开(公告)号：US07115123B2
公开(公告)日：2006-10-03
申请号：US10404883
申请日：2003-03-31
申请人： Edward W. Knowlton , Roger A. Stern , Bryan Weber , Mitchell Levinson
发明人： Edward W. Knowlton , Roger A. Stern , Bryan Weber , Mitchell Levinson
IPC分类号： A61B18/18
CPC分类号： A61B18/14 , A45D44/22 , A61B18/00 , A61B18/0218 , A61B18/12 , A61B18/1206 , A61B18/1402 , A61B18/148 , A61B90/02 , A61B2017/003 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00047 , A61B2018/00452 , A61B2018/00488 , A61B2018/0066 , A61B2018/00702 , A61B2018/00779 , A61B2018/00791 , A61B2018/00875 , A61B2018/00988 , A61B2018/0237 , A61B2018/1495 , A61B2090/064 , A61B2090/065 , A61F2007/0021 , A61H7/001 , A61H9/005 , A61H9/0071 , A61H2201/10 , A61M2205/3606 , A61N1/06 , A61N1/28 , A61N1/30 , A61N1/403 , A61N2005/0645
摘要： An apparatus for cooling a skin surface includes an RF device that has an RF electrode with dielectric and conductive portions. The RF device is configured to be coupled to an RF energy source. A cooling member is coupled to the RF device. A memory is coupled to the RF device. The memory is configured to store information to facilitate operation of at least one of the RF electrode, the cooling member, and the RF energy source.
摘要翻译：用于冷却皮肤表面的装置包括具有电介质和导电部分的RF电极的RF装置。 RF设备被配置为耦合到RF能量源。冷却构件耦合到RF装置。存储器耦合到RF设备。存储器被配置为存储信息以便于RF电极，冷却构件和RF能量源中的至少一个的操作。

32. 发明授权

US07104987B2 Control system and process for application of energy to airway walls and other mediums 有权
标题翻译：控制系统和能量应用于气道壁和其他介质的过程
公开(公告)号：US07104987B2
公开(公告)日：2006-09-12
申请号：US10414411
申请日：2003-04-14
申请人： Michael Biggs , Roger A. Stern , Christopher James Danek
发明人： Michael Biggs , Roger A. Stern , Christopher James Danek
IPC分类号： A61B18/18
CPC分类号： A61N1/06 , A61B18/14 , A61B2018/00541 , A61N1/40
摘要： The present invention includes a system for delivering energy to an airway wall of a lung comprising an energy delivering apparatus and a PID controller having one or more variable gain factors which are rest after energy deliver has begun. The energy delivering apparatus may include a flexible elongated member and a distal expandable basket having at least one electrode for transferring energy to the airway wall and at least one temperature sensor for measuring temperature. The PID controller determines a new power set point base on an error between a preset temperature and the measured temperature. The algorithm can be Pi+1=Pi+G(αei+βei−1+γei−2) where α, β and γ are preset values and α is from 1 to 2; βis from −1 to −2; and γ is from −0.5 to 0−5. In another variation, the controller is configured to shut down if various measured parameters are exceeded such as, for example, energy, impedance, temperature, temperature differences, activation time and combinations thereof. Methods for treating a target medium using a PID algorithm are also provided.
摘要翻译：本发明包括一种用于向肺气道壁输送能量的系统，包括能量输送装置和具有一个或多个可变增益因子的PID控制器，所述可变增益因子在能量传递开始之后休息。能量输送装置可以包括柔性细长构件和远端可膨胀篮，其具有用于将能量传递到气道壁的至少一个电极和用于测量温度的至少一个温度传感器。 PID控制器根据预设温度和测量温度之间的误差确定新的功率设定点。该算法可以是P + 1 + 1 + 1 + 1 + 1 + 其中α，β和γ是预设值，α是1至2; 贝塔从-1到-2; 而γ为-0.5至0-5。在另一变型中，控制器被配置为如果超过各种测量参数，例如能量，阻抗，温度，温差，激活时间及其组合，则关闭。还提供了使用PID算法处理目标介质的方法。

33. 发明授权

US06592223B1 System and method for optimal viewing of computer monitors to minimize eyestrain 失效
公开(公告)号：US06592223B1
公开(公告)日：2003-07-15
申请号：US09680573
申请日：2000-10-06
申请人： Roger A. Stern , Jory E. Moon , Sherwyne R. Bakar
发明人： Roger A. Stern , Jory E. Moon , Sherwyne R. Bakar
IPC分类号： A61B302
CPC分类号： G06F3/013 , A61B3/024 , A61B3/028 , A61B3/032 , A61B3/06 , A61B5/0002 , G06F1/1601 , G06F3/011 , G06F3/14 , G06F2200/1611
摘要： A system and method for helping ensure that a user of a computer is set up to optimally view the computer monitor under optimal conditions in order to minimize eyestrain. The system includes determining an optimal viewing distance and monitoring the distance of a user from the computer monitor during use of the computer. The system further includes notifying the user when they stray from the optimal viewing distance and further may include testing various aspects of the user's eyesight during use of the computer monitor.

34. 发明授权

US06413255B1 Apparatus and method for treatment of tissue 有权
标题翻译：用于治疗组织的装置和方法
公开(公告)号：US06413255B1
公开(公告)日：2002-07-02
申请号：US09522275
申请日：2000-03-09
申请人： Roger A. Stern
发明人： Roger A. Stern
IPC分类号： A61B1818
CPC分类号： A61N5/04 , A61B18/14 , A61B18/1402 , A61B2018/00011 , A61B2018/00023 , A61B2018/00452 , A61B2018/00464 , A61B2018/00702 , A61B2018/00779 , A61B2018/00791 , A61B2018/00875 , A61B2018/1495 , A61B2090/064 , A61N1/403
摘要： An apparatus to treat the skin includes a template having a tissue interface surface and an energy delivery device coupled to the template. The energy delivery device is configured to be coupled to a power source and has a variable resistance portion. A sensor is coupled to one of the template, the energy delivery device, the tissue interface surface or a power source coupled to the energy delivery device. In another embodiment the variable resistance portion configured to reduce an electrode edge effect
摘要翻译：用于治疗皮肤的装置包括具有组织界面表面的模板和耦合到模板的能量输送装置。能量输送装置被配置为耦合到电源并且具有可变电阻部分。传感器耦合到模板，能量输送装置，组织接口表面或耦合到能量输送装置的电源之一。在另一实施例中，可变电阻部分被配置为减小电极边缘效应

35. 发明授权

US6086909A Device and method for treatment of dysmenorrhea 有权
标题翻译：用于治疗痛经的装置和方法
公开(公告)号：US6086909A
公开(公告)日：2000-07-11
申请号：US249963
申请日：1999-02-12
申请人： Donald C. Harrison , James H. Liu , Wolfgang A. Ritschel , Roger A. Stern
发明人： Donald C. Harrison , James H. Liu , Wolfgang A. Ritschel , Roger A. Stern
IPC分类号： A61M31/00 , A61F6/08 , A61F13/20 , A61K9/00 , A61K9/02 , A61K9/08 , A61K31/192 , A61K31/21 , A61K31/27 , A61K31/405 , A61K45/00 , A61P15/00 , A61F6/06 , A61F6/14 , A61F13/02
CPC分类号： A61K9/0034 , A61F6/08 , A61K9/0036
摘要： Methods, devices, and compositions for treatment of dysmenorrhea comprise an intravaginal drug delivery system containing an appropriate pharmaceutical agent incorporated into a pharmaceutically acceptable carrier whereby the pharmaceutical agent is released into the vagina and absorbed through the vaginal mucosa to provide relief of dysmenorrhea. The drug delivery system can be a tampon device, vaginal ring, pessary, tablet, suppository, vaginal medicated tampon, vaginal sponge, bioadhesive tablet, bioadhesive microparticle, cream, lotion, foam, ointment, paste, solution or gel. The system delivers a higher concentration to the muscle of the uterus, the primary site for the dyskinetic muscle contraction, which is the pathophysiologic cause of dysmenorrhea.
摘要翻译：用于治疗痛经的方法，装置和组合物包括阴道内药物递送系统，其包含掺入药学上可接受的载体中的合适的药剂，由此将药剂释放到阴道中并通过阴道粘膜吸收以缓解痛经。药物输送系统可以是棉塞装置，阴道环，子宫托，片剂，栓剂，阴道药物棉塞，阴道海绵，生物粘附片，生物粘附微粒，霜剂，洗剂，泡沫，软膏，糊剂，溶液或凝胶。该系统向子宫肌肉提供更高的浓度，这是运动障碍肌肉收缩的主要部位，这是痛经的病理生理原因。

36. 发明授权

US5533511A Apparatus and method for noninvasive blood pressure measurement 失效
标题翻译：无创血压测量仪器及方法
公开(公告)号：US5533511A
公开(公告)日：1996-07-09
申请号：US177448
申请日：1994-01-05
申请人： William J. Kaspari , Roger A. Stern
发明人： William J. Kaspari , Roger A. Stern
IPC分类号： A61B5/022 , A61B5/00
CPC分类号： A61B5/02007 , A61B5/022 , A61B5/7257 , Y10S128/925
摘要： A blood pressure monitor for determining a patient's blood pressure comprises a processor attached to a first input device for receiving an initial input representing the patient's absolute blood pressure, and a noninvasive sensor attached to the patient for measuring at least one physiological function. The processor executes a procedure for evaluating the initial input and the sensed physiological function to determine the patient's blood pressure. A method for determining a patient's blood pressure comprises the steps of storing an initial input representing a patient's absolute blood pressure, noninvasively sensing at least one of the patient's physiological functions, and evaluating the initial input and the sensed input to determine the patient's blood pressure. The present invention can also be used to analyze and track other physiological variables such as vascular wall compliance, changes in the strength of ventricular contractions, changes in vascular resistance, changes in fluid volume, changes in cardiac output, myocardial contractility and other related factors.
摘要翻译：用于确定患者血压的血压监测器包括附接到第一输入装置的处理器，用于接收表示患者的绝对血压的初始输入，以及附接到患者的用于测量至少一个生理功能的无创传感器。处理器执行用于评估初始输入和感测的生理功能以确定患者的血压的过程。用于确定患者血压的方法包括以下步骤：存储表示患者绝对血压的初始输入，非侵入性地感测患者生理功能中的至少一个，以及评估初始输入和感测输入以确定患者的血压。本发明还可用于分析和跟踪其他生理变量，如血管壁依从性，心室收缩强度变化，血管阻力变化，体积变化，心输出量变化，心肌收缩力等相关因素。

37. 发明授权

US5456682A Electrode and associated systems using thermally insulated temperature sensing elements 失效
标题翻译：使用绝热温度传感元件的电极和相关系统
公开(公告)号：US5456682A
公开(公告)日：1995-10-10
申请号：US191055
申请日：1994-02-02
申请人： Stuart D. Edwards , Roger A. Stern
发明人： Stuart D. Edwards , Roger A. Stern
IPC分类号： A61B18/04 , A61B17/00 , A61B18/00 , A61B18/12 , A61B18/14 , A61B19/00 , A61B17/36
CPC分类号： A61B18/00 , A61B18/1206 , A61B18/1492 , A61B2017/00017 , A61B2017/00101 , A61B2017/00292 , A61B2017/003 , A61B2017/00482 , A61B2018/00101 , A61B2018/00351 , A61B2018/00357 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00684 , A61B2018/00702 , A61B2018/00779 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/00815 , A61B2018/00827 , A61B2018/00869 , A61B2018/00875 , A61B2018/00892 , A61B2018/00916 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2090/0803 , A61B2562/08 , A61M2205/6018 , A61M2205/6027 , A61M2205/70
摘要： An ablation electrode carries a temperature sensing element for measuring the temperature of the tissue being ablated. A thermal insulating element associated with the sensing element blocks the transfer of heat energy from between the temperature sensing element and the body. The temperature sensing element therefore measures temperature without being affected by the surrounding thermal mass of the electrode.
摘要翻译：消融电极携带用于测量正在烧蚀的组织的温度的温度感测元件。与感测元件相关联的绝热元件阻止从温度感测元件和身体之间传递热能。因此，温度感测元件在不受电极的周围热质量影响的情况下测量温度。

38. 发明授权

US5423808A Systems and methods for radiofrequency ablation with phase sensitive power detection 失效
标题翻译：使用相敏检测射频消融的系统和方法
公开(公告)号：US5423808A
公开(公告)日：1995-06-13
申请号：US158809
申请日：1993-11-29
申请人： Stuart D. Edwards , Roger A. Stern
发明人： Stuart D. Edwards , Roger A. Stern
IPC分类号： A61B17/00 , A61B18/12 , A61B18/14 , A61B17/39
CPC分类号： A61B18/1206 , A61B18/12 , A61B18/1492 , A61B2017/00101 , A61B2017/00292 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00767 , A61B2018/00779 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00827 , A61B2018/00869 , A61B2018/00875 , A61B2018/00892 , A61B2018/1253 , A61B2018/1467
摘要： Systems for ablating tissue control radiofrequency power to an ablation electrode by relying upon actual phase sensitive power measurements, unaffected by phase shifts between radiofrequency voltage and current. The systems also detect these phase differences, if they develop, and integrate this factor in making their control decisions.
摘要翻译：通过依赖于实际的相敏功率测量来消融组织控制射频功率到消融电极的系统，不受射频电压和电流之间的相移的影响。系统还会检测这些阶段的差异，如果它们发展，并整合这个因素来做出他们的控制决策。

39. 发明授权

US5281217A Steerable antenna systems for cardiac ablation that minimize tissue damage and blood coagulation due to conductive heating patterns 失效
标题翻译：用于心脏消融的可导向天线系统，可以最大限度地减少由导电加热模式引起的组织损伤和血液凝固
公开(公告)号：US5281217A
公开(公告)日：1994-01-25
申请号：US868031
申请日：1992-04-13
申请人： Stuart D. Edwards , Jerome Jackson , Roger A. Stern , Thomas M. Morse , Patrick M. Owens
发明人： Stuart D. Edwards , Jerome Jackson , Roger A. Stern , Thomas M. Morse , Patrick M. Owens
IPC分类号： A61B18/18 , A61N1/00
CPC分类号： A61B18/18 , A61B18/1815 , A61B2018/1861
摘要： A coaxial antenna assembly conducts a pressurized medium for absorbing heat along the coaxial cable.
摘要翻译：同轴天线组件传导用于沿同轴电缆吸收热量的加压介质。

40. 发明授权

US5277201A Endometrial ablation apparatus and method 失效
标题翻译：子宫内膜消融装置及方法
公开(公告)号：US5277201A
公开(公告)日：1994-01-11
申请号：US877567
申请日：1992-05-01
申请人： Roger A. Stern
发明人： Roger A. Stern
IPC分类号： A61B18/12 , A61B17/00 , A61B17/42 , A61B18/14 , A61N1/06 , A61N1/40 , A61N5/00
CPC分类号： A61N1/06 , A61B18/14 , A61B18/1485 , A61N1/40 , A61B2017/00092 , A61B2017/00101 , A61B2017/00292 , A61B2017/4216 , A61B2018/00065 , A61B2018/00083 , A61B2018/00113 , A61B2018/0016 , A61B2018/0022 , A61B2018/00559 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/124 , A61B2018/1253 , A61B2018/1465 , A61B2018/1467 , A61B2018/162
摘要： An endometrial ablation method comprising passing sufficient RF current having a frequency of from 250 kHz to about 100 MHz through substantially the entire surface of the endometrium to heat the endometrium, in a single operation, to a temperature within the range of from 45.degree. C. to 90.degree. C. and preferably not above 70.degree. C. for a time sufficient to destroy the cells of the lining while maintaining the average temperature of the myometrium at a temperature below about 42.degree. C. The apparatus comprises a electroconductive expandable member such as a balloon for extending the organ and effecting electrical contact with the endometrial lining to be destroyed. The balloon is connected to a power source adapted to provide radiofrequency electric power having the desired characteristics to selectively heat the endometrial lining to the desired temperature. The balloon can be an electroconductive elastomer such as a mixture of a polymeric elastomer and electroconductive particles. Alternatively, it can be a non-extensible bladder having a shape and size, in its fully expanded form, which will extend the organ and effecting contact with the endometrial lining to be destroyed. One surface of the non-extensible bladder can be coated with electroconductive material. The coating can be applied to the inner surface of the non-extensible bladder if the bladder wall thickness is less than about 25 mm.
摘要翻译：子宫内膜消融方法包括通过基本上子宫内膜的整个表面传递具有250kHz至约100MHz的频率的足够的RF电流，以在单次操作中将子宫内膜加热至45℃的温度。至90℃，优选不高于70摄氏度，足以破坏衬里细胞的时间，同时将子宫肌层的平均温度保持在低于约42℃的温度。该装置包括导电性可扩张构件，例如用于延伸器官并与子宫内膜进行电接触以消灭的气球。气球连接到适于提供具有期望特性的射频电力的电源，以选择性地将子宫内膜衬里加热到所需温度。气球可以是导电弹性体，例如聚合物弹性体和导电颗粒的混合物。或者，其可以是具有其完全展开形式的形状和尺寸的不可伸展的囊，其将延伸器官并且与要被破坏的子宫内膜相接触。不可伸展气囊的一个表面可以用导电材料涂覆。如果膀胱壁厚度小于约25毫米，涂层可以施加到不可伸长膀胱的内表面。

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