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31. 发明申请

US20100219941A1 SYSTEM, APPARATUS, AND METHOD FOR PCB-BASED AUTOMATION TRACEABILITY 有权
标题翻译：基于PCB的自动化跟踪的系统，设备和方法
公开(公告)号：US20100219941A1
公开(公告)日：2010-09-02
申请号：US12513913
申请日：2007-11-07
申请人： Chuck Pagano , Richard Keenan
发明人： Chuck Pagano , Richard Keenan
IPC分类号： H04Q5/22
CPC分类号： G06K19/07749 , H01Q1/2225 , H01Q13/10 , H05K1/0266 , H05K2201/093 , H05K2201/09663 , H05K2201/10098
摘要： A system, apparatus, and method are provided for using a PCB component as an antenna to allow for RFID communication in the UHF band. The present invention enables supply chain management of a PCB and products containing the PCB by enabling tracking of a PCB at the assembly level such that at each production stage of the board production it is known exactly where the product is and what is its present state of test. One embodiment uses an existing ground plane of a PCB, splitting the ground plane of all the layers of the PCB, allowing for a dipole structure that provides an adequate received energy level to power the circuit to the “on” state thereby allowing RFID/Electronic Product Code transactions. In alternative embodiments, existing or added traces are used in place of the split ground plane as an antenna for the RFID IC. The supply chain management can employ a dedicated RFID interrogator that is connected to an IT network and allows for bill of materials to be fulfilled in an automated fashion throughout the assembly of the PCB. The manufacturer of the end product can also use the RFID IC in an own end product item level supply management system that includes inventory, shipments, and returns.
摘要翻译：提供了一种使用PCB部件作为天线以允许UHF频带中的RFID通信的系统，装置和方法。本发明通过使得能够在组装级别跟踪PCB来实现PCB和包含PCB的产品的供应链管理，使得在电路板生产的每个生产阶段，已知产品在何处以及其当前状态测试。一个实施例使用PCB的现有接地平面，分割PCB的所有层的接地平面，允许提供足够的接收能级以将电路供电到“接通”状态的偶极结构，从而允许RFID /电子产品代码交易。在替代实施例中，使用现有的或附加的迹线来代替用于RFID IC的天线的分离接地平面。供应链管理可以使用专门的RFID询问器，该询问器连接到IT网络，并允许在PCB的整个组装过程中以自动化方式实现物料清单。最终产品的制造商也可以在自己的最终产品级供应管理系统中使用RFID IC，包括库存，出货和退货。

32. 发明申请

US20100030137A1 APPARATUS AND METHODS FOR ANALYZING BODY FLUID SAMPLES 审中-公开
公开(公告)号：US20100030137A1
公开(公告)日：2010-02-04
申请号：US12511014
申请日：2009-07-28
申请人： W. Dale Hall , David N. Callicoat , Jennifer H. Gable , James R. Braig , Kenneth G. Witte , Mark Wechsler , Peter Rule , Richard Keenan
发明人： W. Dale Hall , David N. Callicoat , Jennifer H. Gable , James R. Braig , Kenneth G. Witte , Mark Wechsler , Peter Rule , Richard Keenan
IPC分类号： A61M5/168
CPC分类号： A61B5/14546 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150358 , A61B5/150755 , A61B5/150862 , A61B5/150992 , A61B5/153 , A61B5/155 , A61B5/157 , A61M5/14212 , A61M2230/20
摘要： An apparatus is provided for monitoring a predetermined parameter of a patient's body fluid while infusing an infusion fluid into the patient. The apparatus comprises an infusion line and a catheter configured for insertion into a blood vessel of the patient, and a reversible infusion pump connected between a source of an infusion fluid and the infusion line and catheter. The apparatus further comprises a body fluid sensor assembly mounted in fluid communication with the infusion line and which includes a first sensor and a sample cell. The first sensor provides a signal indicative of a predetermined parameter of any fluid present in the infusion line. The sample cell is substantially transmissive to light comprising a wavelength λ. The apparatus further comprises a controller that is configured to operate the infusion pump in a forward direction so as to pump the infusion fluid through the infusion line and catheter for infusion into the patient. The controller is configured to intermittently interrupt its operating of the infusion pump in the forward direction to operate the infusion pump in a rearward direction so as to draw a body fluid sample from the patient through the catheter and infusion line. The body fluid sample drawn from the patient is disposed such that a first portion of the body fluid sample is in sensing contact with the first sensor of the body fluid sensor assembly, and a second portion of the body fluid sample is disposed within the sample cell of the body fluid sensor assembly. The controller further is configured to monitor the signal provided by the first sensor of the body fluid sensor assembly and to detect a change in the signal indicative of the arrival of the body fluid sample at the first sensor. The controller, in response to detecting the arrival of the body fluid sample at the first sensor, is configured to cease its operating of the infusion pump in the rearward direction. The signal produced by the first sensor provides an indication of a predetermined parameter of the patient's body fluid when the body fluid sample is in sensing contact with the first sensor.

33. 发明申请

US20090326343A1 FLUID HANDLING CASSETTE HAVING A SPECTROSCOPIC SAMPLE CELL 有权
标题翻译：具有光谱样品池的流体处理箱
公开(公告)号：US20090326343A1
公开(公告)日：2009-12-31
申请号：US12359874
申请日：2009-01-26
申请人： Jennifer H. Gable , James R. Braig , Kenneth I. Li , Mark Wechsler , Peng Zheng , Richard Keenan
发明人： Jennifer H. Gable , James R. Braig , Kenneth I. Li , Mark Wechsler , Peng Zheng , Richard Keenan
IPC分类号： A61B5/15
CPC分类号： A61B5/157 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B5/1411 , A61B5/1427 , A61B5/1451 , A61B5/14517 , A61B5/14532 , A61B5/14535 , A61B5/14546 , A61B5/1455 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150267 , A61B5/150358 , A61B5/150755 , A61B5/150862 , A61B5/150992 , A61B5/153 , A61B5/155 , A61B5/4839 , A61B10/0064 , A61B2560/0443 , A61M5/14212 , A61M5/14232 , A61M5/16854 , A61M5/1723 , A61M5/365 , A61M5/38 , A61M2205/12 , A61M2205/3306 , A61M2230/20 , A61M2230/201 , G01N21/03 , G01N21/3577 , G01N2021/3595 , G01N2201/02 , G01N2201/061 , G06F19/00 , Y10T137/4478 , Y10T137/7722 , Y10T137/86485 , Y10T436/111666 , Y10T436/2575
摘要： A fluid handling module is configured for removable engagement with a reusable main fluid handling instrument. The module includes a module housing and a first fluid passageway extending from the module housing. The first fluid passageway has a patient end remote from the housing. The first fluid passageway is configured to provide fluid communication with a bodily fluid in a patient. A fluid component separator is in fluid communication with the first fluid passageway. The fluid component separator is configured to separate at least one component from a portion of the bodily fluid drawn from the patient. A spectroscopic sample cell is configured to hold at least a portion of the first component.
摘要翻译：流体处理模块被配置为可移除地与可重复使用的主流体处理装置接合。模块包括模块壳体和从模块壳体延伸的第一流体通道。第一流体通道具有远离壳体的患者端。第一流体通道被配置为提供与患者体内的体液的流体连通。流体组分分离器与第一流体通道流体连通。流体部件分离器构造成将至少一个部件与从患者抽出的体液的一部分分离。光谱样品池被配置为保持第一组分的至少一部分。

34. 发明申请

US20080161723A1 INFUSION FLOW INTERRUPTION METHOD AND APPARATUS 审中-公开
标题翻译：输注流中断方法和装置
公开(公告)号：US20080161723A1
公开(公告)日：2008-07-03
申请号：US11850972
申请日：2007-09-06
申请人： Richard Keenan , Jeffrey Chiou , Peter Rule , James R. Braig
发明人： Richard Keenan , Jeffrey Chiou , Peter Rule , James R. Braig
IPC分类号： A61B5/00 , A61M5/142
CPC分类号： A61B5/4839 , A61B5/14532 , A61B5/14557 , A61B5/15003 , A61B5/150221 , A61B5/150229 , A61B5/150236 , A61B5/150244 , A61B5/150267 , A61B5/150305 , A61B5/150755 , A61B5/150786 , A61B5/150824 , A61B5/150854 , A61B5/153 , A61B5/157 , A61M1/3609 , A61M5/14 , A61M5/1415 , A61M2005/1404 , A61M2005/1726 , A61M2230/201
摘要： Disclosed are systems, apparatus and methods for determining information related to analyte(s) (e.g., concentration) in a sample such as biological fluid. An analysis system for determining information relating to at least one analyte in a sample of biological fluid can be configured to: withdraw the sample of biological fluid from the source of biological fluid; interrupt the flow of infusion fluid while the sample of biological fluid is withdrawn; analyze the withdrawn biological fluid to determine information relating to at least one analyte; and resume the flow of infusion fluid after the sample of biological fluid is withdrawn. A method of interrupting flow of an infusion fluid without triggering an alarm can comprise, while the flow of the infusion fluid is interrupted, diverting the flow of the infusion fluid from a fluid passageway to an expandable volume at a rate that maintains constant flow from an infusion pump.
摘要翻译：公开了用于确定样品（例如生物流体）中与分析物（例如浓度）相关的信息的系统，装置和方法。用于确定与生物流体样品中的至少一种分析物相关的信息的分析系统可以被配置为：从生物流体源中抽出生物流体的样品; 中断生物流体样本取出时输液的流动; 分析所抽取的生物流体以确定与至少一种分析物有关的信息; 并在取出生物流体的样品后恢复输注液的流动。一种在不触发报警的情况下中断输注流体的流动的方法可以包括在输注流体的流动被中断的同时将输注流体的流动从流体通道转移到可膨胀体积，其速率保持恒定的流量输液泵。

35. 发明授权

US07388202B2 Method and apparatus for determining an analyte concentration in a sample having interferents 有权
标题翻译：用于确定具有干扰物的样品中的分析物浓度的方法和装置
公开(公告)号：US07388202B2
公开(公告)日：2008-06-17
申请号：US11256656
申请日：2005-10-21
申请人： Bernhard B. Sterling , W. Dale Hall , Kenneth G. Witte , Mark Wechsler , Peng Zheng , Richard Keenan
发明人： Bernhard B. Sterling , W. Dale Hall , Kenneth G. Witte , Mark Wechsler , Peng Zheng , Richard Keenan
IPC分类号： G01J1/00 , G01N21/35
CPC分类号： G01N21/274 , A61B5/14532 , A61B5/14535 , A61B5/14546 , A61B5/1459 , A61B5/1495 , A61B2560/0223 , A61M5/14212 , A61M2230/20 , G01N21/35 , G01N35/00693 , G01N35/00712 , G01N2201/1215 , G01N2201/127
摘要： A method and apparatus are described that permit an analyte concentration to be estimated from a measurement in the presence of compounds that interfere with the measurement. The method reduces the error in the analyte concentration in the presence of interferents. The method includes the use of a set of measurements obtained for a large population having a range of known analyte and interfering compound concentrations. From a sample measurement, which may or may not be one of the population, likely present interferents are identified, and a calibration vector is calculated.
摘要翻译：描述了允许在干扰测量的化合物存在下从测量估计分析物浓度的方法和装置。该方法减少了在存在干扰物的情况下分析物浓度的误差。该方法包括使用对具有已知分析物范围和干扰化合物浓度的大群体获得的一组测量。从可能或可能不是其中一个群体的样本测量中，可能存在干扰物被识别，并且计算校准向量。

36. 发明申请

US20070239096A1 ANTI-CLOTTING APPARATUS AND METHODS FOR FLUID HANDLING SYSTEM 有权
标题翻译：用于流体处理系统的防粘装置和方法
公开(公告)号：US20070239096A1
公开(公告)日：2007-10-11
申请号：US11734242
申请日：2007-04-11
申请人： Richard Keenan , Jeff Chiou
发明人： Richard Keenan , Jeff Chiou
IPC分类号： A61M37/00
CPC分类号： G01N29/00 , A61B5/14532 , A61B5/14546 , A61B5/14557 , A61M1/3672 , A61M5/1723 , A61M2005/1404 , A61M2205/3306 , A61M2230/201
摘要： Methods and apparatus are provided for determining the concentration of an analyte in a sample, such as an analyte in a sample of bodily fluid. In some embodiments, a method for maintaining clear passageways in an extracorporeal blood flow system includes intermittently providing one or more anti-clotting agents to a passageway of the extracorporeal blood flow system. In some embodiments, an extracorporeal blood flow system includes a passageway and a device operatively connected to provide one or more anti-clotting agents to a least a portion of said passageway.
摘要翻译：提供了用于确定样品（例如体液样品中的分析物）中的分析物的浓度的方法和装置。在一些实施方案中，用于在体外血流系统中维持清晰通道的方法包括间歇地向体外血流系统的通道提供一种或多种抗凝血剂。在一些实施方案中，体外血液流动系统包括通路和操作性连接的装置，以向所述通道的至少一部分提供一种或多种抗凝血剂。

37. 发明申请

US20070132510A1 Preserving linearity of an isolator-free power amplifier by dynamically switching active devices 有权
标题翻译：通过动态切换主动来保持无隔离器功率放大器的线性度
公开(公告)号：US20070132510A1
公开(公告)日：2007-06-14
申请号：US10538624
申请日：2003-12-10
申请人： Saleh Osman , Richard Keenan , Jaroslaw Lucek
发明人： Saleh Osman , Richard Keenan , Jaroslaw Lucek
IPC分类号： H03F1/14
CPC分类号： H03F1/0277 , H03F1/32 , H03F1/52 , H03F2200/294 , H03F2200/372 , H03G1/0088
摘要： An amplifier circuit (100) includes a driver stage (120) with active devices (140) for pre-amplification and output of a pre-amplified signal; and an output stage (160) with active devices (180) for further amplification of the pre-amplified signal and output of an amplified signal. A detector (190) measures levels of forward and reflected parts of the amplified signal, and a control circuit (145) independently and selectively controls turning on and off of the active devices (140, 180) of the driver and output stages (120, 160) as a function of the levels of the forward and reflected signals to substantially maintain linearity of the amplifier circuit (100) with load variations.
摘要翻译：放大器电路（100）包括具有有源器件（140）的驱动器级（120），用于预放大和预放大信号的输出; 以及具有用于进一步放大预放大信号和输出放大信号的有源器件（180）的输出级（160）。检测器（190）测量放大信号的正向和反射部分的电平，并且控制电路（145）独立地并且选择性地控制驱动器和输出级（120,180）的有源器件（140,180）的导通和截止， 160）作为正向和反射信号的电平的函数，以基本上保持放大器电路（100）的负载变化的线性。

38. 发明申请

US20060235348A1 Method of extracting and analyzing the composition of bodily fluids 审中-公开
标题翻译：提取和分析体液组成的方法
公开(公告)号：US20060235348A1
公开(公告)日：2006-10-19
申请号：US11314964
申请日：2005-12-21
申请人： David Callicoat , Jennifer Gable , James Braig , Kenneth Witte , Mark Wechsler , Peng Zheng , Peter Rule , Richard Keenan , Richard King
发明人： David Callicoat , Jennifer Gable , James Braig , Kenneth Witte , Mark Wechsler , Peng Zheng , Peter Rule , Richard Keenan , Richard King
IPC分类号： A61M31/00 , A61M37/00 , A61B5/00
CPC分类号： A61B5/157 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B5/1411 , A61B5/1427 , A61B5/1451 , A61B5/14517 , A61B5/14532 , A61B5/14535 , A61B5/14546 , A61B5/1455 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150267 , A61B5/150358 , A61B5/150755 , A61B5/150862 , A61B5/150992 , A61B5/153 , A61B5/155 , A61B5/4839 , A61B10/0064 , A61B2560/0443 , A61M5/14212 , A61M5/14232 , A61M5/16854 , A61M5/1723 , A61M5/365 , A61M5/38 , A61M2205/12 , A61M2205/3306 , A61M2230/20 , A61M2230/201 , G01N21/03 , G01N21/3577 , G01N2021/3595 , G01N2201/02 , G01N2201/061 , Y10T137/4478 , Y10T137/7722 , Y10T137/86485 , Y10T436/111666 , Y10T436/2575
摘要： A method of extracting and analyzing bodily fluids from a patient at the point of care for the patient is provided. The method comprises establishing fluid communication between an analyte detection system and a bodily fluid in the patient. A portion of the bodily fluid is drawn from the patient. The drawn portion is separated into a first component of the bodily fluid, while the analyte detection system remains in fluid communication with the patient. The analyte detection system analyzes the first component to measure a concentration of an analyte.
摘要翻译：提供了在患者护理点从患者提取和分析体液的方法。该方法包括在患者体内建立分析物检测系统和体液之间的流体连通。体液的一部分从患者身上抽出。被抽取的部分被分离成体液的第一组分，而分析物检测系统保持与患者的流体连通。分析物检测系统分析第一组分以测量分析物的浓度。

39. 发明申请

US20060189858A1 Analyte detection system for multiple analytes 有权
标题翻译：多种分析物的分析物检测系统
公开(公告)号：US20060189858A1
公开(公告)日：2006-08-24
申请号：US11314176
申请日：2005-12-21
申请人： Bernhard Sterling , James Braig , Kenneth Witte , Peter Rule , Richard Keenan , W. Hall
发明人： Bernhard Sterling , James Braig , Kenneth Witte , Peter Rule , Richard Keenan , W. Hall
IPC分类号： A61B5/00 , A61M31/00
CPC分类号： A61M5/1723 , A61B5/14532 , A61B5/14546 , A61B5/14557 , A61B5/1495 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150755 , A61B5/150862 , A61B5/150992 , A61B5/153 , A61B5/155 , A61B5/157 , A61M5/14212 , A61M5/14232 , A61M5/16854 , A61M2205/12 , A61M2230/20 , A61M2230/201 , G01N1/14 , G01N21/05 , G01N21/274 , G01N21/35 , G01N2021/0346
摘要： An apparatus for analyzing the composition of bodily fluid. The apparatus comprises a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient; and a pump unit in operative engagement with the fluid handling network. The pump unit has an infusion mode in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus further comprises a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample. In one implementation, the pump unit comprises a first pump operable in the infusion mode but not in the sample draw mode, and a second pump operable in the sample draw mode but not in the infusion mode.
摘要翻译：一种用于分析体液组成的装置。该装置包括流体处理网络，其包括被配置为保持患者体内与体液的流体连通的患者端; 以及与所述流体处理网络操作地接合的泵单元。泵单元具有输注模式，其中泵单元可操作以通过患者端向患者输送输注流体，以及抽样模式，其中泵单元可操作以从患者抽取体液样本，通过病人结束所述设备还包括定位成分析样品的至少一部分的光谱分析仪; 与光谱分析仪通信或并入其中的处理器; 以及可由处理器执行的存储的程序指令，以获得样本的两个或多个属性的测量。在一个实施方案中，泵单元包括可在输液模式中操作但不在样品抽取模式中的第一泵，以及可在样品抽取模式中操作但不在输注模式中的第二泵。

40. 发明申请

US20060188407A1 Fluid handling cassette having a spectroscopic sample cell 有权
公开(公告)号：US20060188407A1
公开(公告)日：2006-08-24
申请号：US11316672
申请日：2005-12-21
申请人： Jennifer Gable , James Braig , Kenneth Li , Mark Wechsler , Peng Zheng , Richard Keenan
发明人： Jennifer Gable , James Braig , Kenneth Li , Mark Wechsler , Peng Zheng , Richard Keenan
IPC分类号： B01L3/00
CPC分类号： A61B5/157 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B5/1411 , A61B5/1427 , A61B5/1451 , A61B5/14517 , A61B5/14532 , A61B5/14535 , A61B5/14546 , A61B5/1455 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150267 , A61B5/150358 , A61B5/150755 , A61B5/150862 , A61B5/150992 , A61B5/153 , A61B5/155 , A61B5/4839 , A61B10/0064 , A61B2560/0443 , A61M5/14212 , A61M5/14232 , A61M5/16854 , A61M5/1723 , A61M5/365 , A61M5/38 , A61M2205/12 , A61M2205/3306 , A61M2230/20 , A61M2230/201 , G01N21/03 , G01N21/3577 , G01N2021/3595 , G01N2201/02 , G01N2201/061 , G06F19/00 , Y10T137/4478 , Y10T137/7722 , Y10T137/86485 , Y10T436/111666 , Y10T436/2575
摘要： A fluid handling module is configured for removable engagement with a reusable main fluid handling instrument. The module includes a module housing and a first fluid passageway extending from the module housing. The first fluid passageway has a patient end remote from the housing. The first fluid passageway is configured to provide fluid communication with a bodily fluid in a patient. A fluid component separator is in fluid communication with the first fluid passageway. The fluid component separator is configured to separate at least one component from a portion of the bodily fluid drawn from the patient. A spectroscopic sample cell is configured to hold at least a portion of the first component.

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