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31. 发明授权

US5788689A Prosthetic heart valve rotator tool 失效
标题翻译：假心脏心脏旋转器工具
公开(公告)号：US5788689A
公开(公告)日：1998-08-04
申请号：US594972
申请日：1996-01-31
申请人： Bob Allan , Kimberly A. Anderson , William R. Holmberg , Kurt D. Krueger , Michael J. Girard , Thomas G. Schoon , Gary G. Rushmeyer
发明人： Bob Allan , Kimberly A. Anderson , William R. Holmberg , Kurt D. Krueger , Michael J. Girard , Thomas G. Schoon , Gary G. Rushmeyer
IPC分类号： A61F2/24 , A61B17/00
CPC分类号： A61F2/2427
摘要： A prosthetic heart valve rotator tool operates in the small chest cavity available to the surgeon, having parts that can be easily assembled and disassembled, allowing it to be cleaned and sterilized for repeated use.
摘要翻译：假体心脏瓣膜旋转器工具在外科医生可用的小胸腔中操作，具有易于组装和拆卸的部件，允许其被清洁和消毒以重复使用。

32. 发明授权

US08398704B2 Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient 有权
标题翻译：用于在患者心脏中的植入部位中定位和锚定瓣膜假体的支架
公开(公告)号：US08398704B2
公开(公告)日：2013-03-19
申请号：US12713058
申请日：2010-02-25
申请人： Helmut Straubinger , Johannes Jung , Michael J. Girard , Arnulf Mayer
发明人： Helmut Straubinger , Johannes Jung , Michael J. Girard , Arnulf Mayer
IPC分类号： A61F2/82 , A61F2/24
CPC分类号： A61F2/2418 , A61F2220/0016 , A61F2220/0058 , A61F2220/0075 , A61F2230/0023 , A61F2230/0054
摘要： The present invention relates to a stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis fastened to a stent will occur relative the stent in the implanted state of the stent, even given the peristaltic motion of the heart, the stent according to the invention comprises at least one fastening portion via which the valvular prosthesis is connectable to the stent. The stent further comprises positioning arches and retaining arches, whereby at least one positioning arch is connected to at least one retaining arch.
摘要翻译：本发明涉及一种用于在患者心脏中的植入部位定位和锚定瓣膜假体的支架。具体地，本发明涉及用于治疗心脏瓣膜变窄和/或心脏瓣膜功能不全的内用假体的可扩张支架。为了确保即使给予心脏的蠕动运动，固定在支架上的瓣膜假体也不会相对于支架的植入状态发生纵向位移，所以根据本发明的支架包括至少一个紧固部分瓣膜假体可以通过其连接到支架上。支架还包括定位拱门和保持拱门，由此至少一个定位弓连接到至少一个保持拱。

33. 发明申请

US20110295363A1 Prosthetic Heart Valve And Transcatheter Delivered Endoprosthesis Comprising A Prosthetic Heart Valve And A Stent 有权
标题翻译：假性心脏瓣膜和经导管交付假体心脏瓣膜和支架的内置假体
公开(公告)号：US20110295363A1
公开(公告)日：2011-12-01
申请号：US13114582
申请日：2011-05-24
申请人： Michael J. Girard , Randy Lane , Arnulf Mayer
发明人： Michael J. Girard , Randy Lane , Arnulf Mayer
IPC分类号： A61F2/82 , A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2220/0025 , A61F2220/0075 , A61F2240/001
摘要： The invention relates to a prosthetic heart valve (100) for an endoprosthesis (1) used in the treatment of a stenotic cardiac valve and/or a cardiac valve insufficiency. The prosthetic heart valve (100) comprises of a plurality of leaflets (102), which consist of a natural and/or synthetic material and have a first opened position for opening the heart chamber and a second closed position for closing the heart chamber, the leaflets (102) being able to switch between their first and second position in response to the blood flow through the heart. In addition, the prosthetic heart valve (100) comprises a leaflet support portion (103), consisting of biological and/or synthetic material for mounting of the prosthetic heart valve (100) to a stent (10), and a bendable transition area (104) which forms a junction between the leaflets (102) and the leaflet support portion (103), the transition area (104) progressing essentially in a U-shaped manner similar to a cusp shape of a natural aortic or pulmonary heart valve for reducing tissue stresses during opening and closing motion of the leaflets (102). The invention further relates to an endoprosthesis (1) comprising a prosthetic heart valve (100) and a stent (10)
摘要翻译：本发明涉及用于治疗狭窄心脏瓣膜和/或心脏瓣膜功能不全的内用假体（1）的假体心脏瓣膜（100）。所述假体心脏瓣膜（100）包括由天然和/或合成材料组成并且具有用于打开心室的第一打开位置和用于闭合心室的第二闭合位置的多个小叶（102），小叶（102）能够响应于通过心脏的血流而在它们的第一和第二位置之间切换。此外，假体心脏瓣膜（100）包括由用于将假体心脏瓣膜（100）安装到支架（10）的生物和/或合成材料组成的小叶支撑部分（103）和可弯曲的过渡区域 104），其形成在小叶（102）和小叶支撑部分（103）之间的连接处，过渡区域（104）基本上以类似于天然主动脉或肺心脏瓣膜的尖端形状的U形方式前进，用于还原在小叶（102）的打开和关闭运动期间的组织应力。本发明还涉及一种包括假体心脏瓣膜（100）和支架（10）的内用假体（1）

34. 发明申请

US20110208290A1 STENT FOR THE POSITIONING AND ANCHORING OF A VALVULAR PROSTHESIS IN AN IMPLANTATION SITE IN THE HEART OF A PATIENT 有权
标题翻译：在患者心脏中的植入位置的定位和锚定的固定
公开(公告)号：US20110208290A1
公开(公告)日：2011-08-25
申请号：US13033023
申请日：2011-02-23
申请人： Helmut Straubinger , Johannes Jung , Michael J. Girard , Arnulf Mayer
发明人： Helmut Straubinger , Johannes Jung , Michael J. Girard , Arnulf Mayer
IPC分类号： A61F2/82
CPC分类号： A61F2/2418 , A61F2/07 , A61F2/2412 , A61F2220/0058 , A61F2220/0075 , A61F2230/0023 , A61F2230/0054
摘要： The present invention relates to a stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis fastened to a stent will occur relative the stent in the implanted state of the stent, even given the peristaltic motion of the heart, the stent according to the invention comprises at least one fastening portion via which the valvular prosthesis is connectable to the stent. The stent further comprises positioning arches and retaining arches, whereby at least one positioning arch is connected to at least one retaining arch.
摘要翻译：本发明涉及一种用于在患者心脏中的植入部位定位和锚定瓣膜假体的支架。具体地，本发明涉及用于治疗心脏瓣膜变窄和/或心脏瓣膜功能不全的内用假体的可扩张支架。为了确保即使给予心脏的蠕动运动，固定在支架上的瓣膜假体也不会相对于支架的植入状态发生纵向位移，所以根据本发明的支架包括至少一个紧固部分瓣膜假体可以通过其连接到支架上。支架还包括定位拱门和保持拱门，由此至少一个定位弓连接到至少一个保持拱。

35. 发明授权

US06174279B1 Cardiac constraint with tension indicator 有权
标题翻译：心脏约束与张力指示器
公开(公告)号：US06174279B1
公开(公告)日：2001-01-16
申请号：US09400018
申请日：1999-09-21
申请人： Michael J. Girard
发明人： Michael J. Girard
IPC分类号： A61F1300
CPC分类号： A61F2/2481
摘要： A method and apparatus for treating congestive heart disease and related cardiac complications such as valvular disorders and includes a constraining device placed on the heart. The constraining device is a jacket of flexible material of knit construction defining a volume between an open upper end and a lower end. The jacket is dimensioned for the apex of the heart to be inserted into the volume through the open upper end and for the jacket to be slipped over the heart. The jacket is further dimensioned for the jacket to have a longitudinal dimension between the upper and lower ends sufficient for said jacket to constrain said lower portion of the heart. The jacket adapted to be adjusted on the heart to snugly conform to an external geometry of the heart to constrain circumferential expansion of the heart beyond. The jacket includes an indicator for indicating when the jacket is adjusted on the heart to a desired degree of tensioning
摘要翻译：一种用于治疗充血性心脏病和相关心脏并发症如瓣膜疾病的方法和装置，并且包括置于心脏上的约束装置。约束装置是编织结构的柔性材料的夹套，其限定开口上端和下端之间的体积。外套的尺寸适合心脏的顶点，通过开放的上端插入体积，并使护套滑过心脏。护套的尺寸进一步尺寸用于护套具有在上端和下端之间的纵向尺寸，足以使所述夹克限制心脏的所述下部。适合在心脏上进行调节的外套适合于心脏的外部几何形状以约束心脏的周向扩张。护套包括用于指示何时将护套在心脏上调节到期望的张紧程度的指示器

36. 发明授权

US5910170A Prosthetic heart valve stent utilizing mounting clips 失效
标题翻译：假体心脏瓣膜支架利用安装夹
公开(公告)号：US5910170A
公开(公告)日：1999-06-08
申请号：US992595
申请日：1997-12-17
申请人： Matthew S. Reimink , Richard F. Schroeder , M. William Mirsch, II , Michael J. Girard
发明人： Matthew S. Reimink , Richard F. Schroeder , M. William Mirsch, II , Michael J. Girard
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , Y10S623/90
摘要： The present invention includes a prosthetic heart valve having a stent and a piece of biocompatible material. The stent includes an inflow ring and a plurality of posts, each post extending from the ring to a post tip. The piece of material extends over the stent and substantially conforms to a profile of the stent. The piece of material includes a portion which extends adjacent a post tip. A clip is provided which has a shape generally conforming to the post tip to thereby clamp the portion of the piece of material to the post tip.
摘要翻译：本发明包括具有支架和一片生物相容性材料的假体心脏瓣膜。支架包括流入环和多个柱，每个柱从环延伸到后端。该块材料在支架上延伸并且基本上符合支架的轮廓。材料片包括一个邻近一个后端延伸的部分。提供了一种夹子，其具有大致与柱塞顶端相符的形状，从而将该部分材料夹紧到后端。

37. 发明授权

US5876436A Rotatable cuff assembly for a heart valve prosthesis 失效
标题翻译：用于心脏瓣膜假体的可旋转袖带组件
公开(公告)号：US5876436A
公开(公告)日：1999-03-02
申请号：US799289
申请日：1997-02-13
申请人： Guy P. Vanney , Michael J. Girard , William R. Kramlinger , Jonas A. Runquist , Kimberly A. Anderson , Scott D. Moore , Bob Allan , James E. Graf
发明人： Guy P. Vanney , Michael J. Girard , William R. Kramlinger , Jonas A. Runquist , Kimberly A. Anderson , Scott D. Moore , Bob Allan , James E. Graf
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , Y10S623/90
摘要： The invention provides a sewing cuff assembly for mounting to the body of a heart valve prosthesis. The sewing cuff assembly comprises a resiliently deformed spring for exerting a force directed toward the orifice structure. When a torque is applied to the valve, the force results in a rotation-resisting torque sufficient to resist rotation during normal operation of the valve after implantation but low enough to permit assisted rotation, as during surgery.
摘要翻译：本发明提供了一种用于安装到心脏瓣膜假体的身体的缝合袖带组件。缝合袖带组件包括弹性变形的弹簧，用于施加指向孔结构的力。当扭矩施加到阀门时，力将导致旋转阻力转矩足以在植入后阀门的正常操作期间抵抗旋转，但足够低以允许辅助旋转，如在手术期间。

38. 发明授权

US5843179A Suture guard for prosthetic heart valve 失效
标题翻译：假体心脏瓣膜缝合护罩
公开(公告)号：US5843179A
公开(公告)日：1998-12-01
申请号：US734360
申请日：1996-10-21
申请人： Guy P. Vanney , Deborah A. Loch , Kimberly A. Anderson , Susan M. Mulvaney , Kurt D. Krueger , Michael J. Girard
发明人： Guy P. Vanney , Deborah A. Loch , Kimberly A. Anderson , Susan M. Mulvaney , Kurt D. Krueger , Michael J. Girard
IPC分类号： A61F2/24
CPC分类号： A61F2/2409
摘要： A heart valve prosthesis for use in a heart includes an orifice defining a lumen therethrough for blood flow. An occluder is carried in the orifice and is movable between an open position which allows blood flow through the lumen and a closed position in which flow through the lumen is blocked. A suture cuff coupled to the orifice extends around an outer circumference of the orifice and is used for attaching the heart valve to a heart tissue annulus using sutures. The sutures are knotted proximate the suture cuff to secure the cuff to the annulus. A suture guard is coupled to the suture cuff and is movable between an open position in which the suture knot is exposed and a closed position in which the suture, suture knot and suture cuff are covered.
摘要翻译：在心脏中使用的心脏瓣膜假体包括限定用于血液流动的腔的孔。封堵器被携带在孔口中，并且可以在允许血液流过管腔的打开位置和闭合位置之间移动，在关闭位置，流过管腔的流动被阻塞。联接到孔的缝合箍围绕孔的外周延伸，并且用于使用缝线将心脏瓣膜附接到心脏组织环。缝合线缝合在缝合袖口附近，以将袖带固定在环状物上。缝合线保护件联接到缝合箍上，并且可以在其中暴露缝合线的打开位置和闭合位置之间移动，缝合线，缝线结和缝合箍被覆盖在闭合位置。

39. 发明授权

US5776187A Combined holder tool and rotator for a prosthetic heart valve 失效
标题翻译：用于假体心脏瓣膜的组合支架工具和旋转器
公开(公告)号：US5776187A
公开(公告)日：1998-07-07
申请号：US692396
申请日：1996-08-05
申请人： Kurt D. Krueger , Averdon M. DeLeon , William S. Nettekoven , Kimberly A. Anderson , Michael J. Girard
发明人： Kurt D. Krueger , Averdon M. DeLeon , William S. Nettekoven , Kimberly A. Anderson , Michael J. Girard
IPC分类号： A61F2/24
CPC分类号： A61F2/2427
摘要： The invention relates to a holder/rotator device which may be used to hold and then rotate a heart valve prosthesis during implantation of the heart valve prosthesis. The device comprises holder/rotator which includes a post and a rotator head, and a handle. The rotator head comprises a gripping surface of a material which engages and grips the surface of the heart valve prosthesis and facilitates the smooth rotation of the valve.
摘要翻译：本发明涉及一种保持器/转子装置，其可用于在心脏瓣膜假体植入期间保持心脏瓣膜假体并随后旋转心脏瓣膜假体。该装置包括保持器/旋转器，其包括柱和旋转头以及手柄。旋转头包括与心脏瓣膜假体接合并夹紧心脏瓣膜假体的表面并有助于瓣膜平滑旋转的材料的抓握表面。

40. 发明授权

US5571175A Suture guard for prosthetic heart valve 失效
标题翻译：假体心脏瓣膜缝合护罩
公开(公告)号：US5571175A
公开(公告)日：1996-11-05
申请号：US487497
申请日：1995-06-07
申请人： Guy Vanney , Kurt D. Krueger , Michael J. Girard
发明人： Guy Vanney , Kurt D. Krueger , Michael J. Girard
IPC分类号： A61F2/24
CPC分类号： A61F2/2409
摘要： An artificial heart valve prosthesis for use in a heart includes an orifice defining a lumen therethrough for blood flow. An occluder is carried in the orifice and is movable between an open position which allows blood flow through the lumen and a closed position in which flow through the lumen is blocked. A suture cuff coupled to the orifice extends around an outer circumference of the orifice and is used for attaching the heart valve to a heart tissue annulus using sutures. The sutures are knotted proximate the suture cuff to secure the cuff to the annulus. A suture guard is coupled to the suture cuff and is movable between an open position in which the suture knot is exposed and a closed position in which the suture, suture knot and suture cuff are covered.
摘要翻译：在心脏中使用的人造心脏瓣膜假体包括限定用于血液流动的腔的孔。封堵器被携带在孔口中，并且可以在允许血液流过管腔的打开位置和闭合位置之间移动，在关闭位置，流过管腔的流动被阻塞。联接到孔的缝合箍围绕孔的外周延伸，并且用于使用缝线将心脏瓣膜附接到心脏组织环。缝合线缝合在缝合袖口附近，以将袖带固定在环状物上。缝合线保护件联接到缝合箍上，并且可以在其中暴露缝合线的打开位置和闭合位置之间移动，缝合线，缝线结和缝合箍被覆盖在闭合位置。

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