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31. 发明授权

US06507664B1 Two-dimensional gels for separation, identification and characterization of biomolecules 失效
标题翻译：用于分离，鉴定和表征生物分子的二维凝胶
公开(公告)号：US06507664B1
公开(公告)日：2003-01-14
申请号：US09642246
申请日：2000-08-17
申请人： N. Leigh Anderson , Norman G. Anderson , Jack Goodman
发明人： N. Leigh Anderson , Norman G. Anderson , Jack Goodman
IPC分类号： G06K900
CPC分类号： G01N27/44795 , G01N27/44773 , G01N27/44782 , G01N2001/288 , Y10T436/113332 , Y10T436/25 , Y10T436/25375 , Y10T436/255
摘要： The present invention provides an integrated, fully automated, high-throughput system for two-dimensional electrophoresis comprised of gel-making machines, gel processing machines, gel compositions and geometries, gel handling systems, sample preparation systems, software and methods. The system is capable of continuous operation at high-throughput to allow construction of large quantitative data sets.
摘要翻译：本发明提供了一种用于由凝胶制造机，凝胶加工机，凝胶组合物和几何形状，凝胶处理系统，样品制备系统，软件和方法组成的二维电泳的集成的全自动化高通量系统。该系统能够以高通量连续运行，从而构建大量的数据集。

32. 发明授权

US06464629B1 Method and apparatus for temporarily immobilizing a local area of tissue 有权
标题翻译：临时固定组织局部区域的方法和装置
公开(公告)号：US06464629B1
公开(公告)日：2002-10-15
申请号：US09396047
申请日：1999-09-15
申请人： Eric Boone , Jack Goodman , John D. Hall , William G. O'Neill , Vincent J. Testa , Eric Vroegop , Cornelius Borst , Hendricus J. Mansvelt-Beck , Paul F. Gründeman
发明人： Eric Boone , Jack Goodman , John D. Hall , William G. O'Neill , Vincent J. Testa , Eric Vroegop , Cornelius Borst , Hendricus J. Mansvelt-Beck , Paul F. Gründeman
IPC分类号： A61F200
CPC分类号： A61B17/02 , A61B17/0218 , A61B2017/00314 , A61B2017/0243 , A61B2017/2904 , A61B2017/2905 , A61B2017/306
摘要： The invention is a method and apparatus for performing beating heart surgery, in which a single articulating arm supports multiple suction pods. Once the suction pods are applied to the heart surface, tightening a cable fixes the arm in place. Then, the suction pods may be spread apart from each other to tighten the surface of the cardiac tissue lying between the suction pods. In one embodiment, fixation of the arm as well as the spreading apart of the suction pods may occur concurrently or almost concurrently through the tensioning of a single cable. Additional embodiments of the method, system and its components are shown.
摘要翻译：本发明是一种用于进行心跳手术的方法和装置，其中单个关节臂支撑多个抽吸荚。一旦吸入荚被施加到心脏表面上，紧固电缆将臂固定到位。然后，抽吸荚可以彼此分开，以紧固位于抽吸荚之间的心脏组织的表面。在一个实施例中，臂的固定以及吸入舱的扩展分开可以通过单个电缆的张紧同时或几乎同时地发生。示出了该方法，系统及其部件的附加实施例。

33. 发明授权

US06416644B1 Automated system for two-dimensional electrophoresis 失效
公开(公告)号：US06416644B1
公开(公告)日：2002-07-09
申请号：US09680443
申请日：2000-10-06
申请人： N. Leigh Anderson , Norman G. Anderson , Jack Goodman
发明人： N. Leigh Anderson , Norman G. Anderson , Jack Goodman
IPC分类号： G01N2726
CPC分类号： G01N27/44795 , G01N27/44773 , G01N27/44782 , G01N2001/288 , Y10T436/113332 , Y10T436/25 , Y10T436/25375 , Y10T436/255
摘要： The present invention provides an integrated, fully automated, high-throughput system for two-dimensional electrophoresis comprised of gel-making machines, gel processing machines, gel compositions and geometries, gel handling systems, sample preparation systems, software and methods. The system is capable of continuous operation at high-throughput to allow construction of large quantitative data sets.

34. 发明授权

US5964703A Extravasation detection electrode patch 失效
标题翻译：外渗检测电极贴片
公开(公告)号：US5964703A
公开(公告)日：1999-10-12
申请号：US957121
申请日：1997-10-24
申请人： Jack Goodman , Arthur Zimmet
发明人： Jack Goodman , Arthur Zimmet
IPC分类号： A61B5/053 , A61M5/168 , A61B5/04
CPC分类号： A61B5/0535 , A61M5/16836
摘要： A medical extravasation device has an electrode patch that can attach to the skin for sensing electrical information. Tissue impedance is calculated from the electrode patch signals. The patch has elongate pick-up electrodes inboard of elongate energizing electrodes. The measuring zone determined by the elongate space between the pick-up electrodes enhances sensitivity and specificity. The presence of an extravasation is determined by interpreting the tissue impedance measurement. The method for determining the extravasation includes a first step of determining a pre-injection baseline measurement of the tissue impedance. Then, the tissue impedance is monitored during the procedure itself. A predetermined amount of change in tissue impedance is determined to indicate an extravasation.
摘要翻译：医疗外渗装置具有电极贴片，其可以附着到皮肤以感测电信息。从电极贴片信号计算组织阻抗。该贴片在细长的激励电极内部具有细长的拾取电极。由拾取电极之间的细长空间确定的测量区域提高了灵敏度和特异性。通过解释组织阻抗测量来确定外渗的存在。用于确定外渗的方法包括确定组织阻抗的预注射基线测量的第一步骤。然后，在程序本身期间监测组织阻抗。确定组织阻抗的预定量的变化以指示外渗。

35. 发明授权

US5768647A Camera positioning assembly 失效
标题翻译：摄像机定位组件
公开(公告)号：US5768647A
公开(公告)日：1998-06-16
申请号：US759700
申请日：1996-12-06
申请人： Jeffrey S. Coffin , Jack Goodman
发明人： Jeffrey S. Coffin , Jack Goodman
IPC分类号： G03B17/00 , G03B17/56
CPC分类号： G03B17/561
摘要： A camera positioning assembly including a backing board, a base member connected to said backing board about an axis, a gear adapted for rotational movement, an arm connected to said gear and said base member for moving said base member about said axis in order that rotational movement of said gear is translated into rotational movement of said base member and a servo-controller that controls the rotational movement of said gear.
摘要翻译：一种照相机定位组件，包括背板，与所述背板相关的轴线连接的基座构件，适于旋转移动的齿轮，连接到所述齿轮的臂，以及用于使所述基座构件围绕所述轴线移动的臂，以便旋转所述齿轮的运动转换成所述基座部件的旋转运动和控制所述齿轮的旋转运动的伺服控制器。

36. 发明授权

US5343909A Liquid transfer device 失效
标题翻译：液体转移装置
公开(公告)号：US5343909A
公开(公告)日：1994-09-06
申请号：US81051
申请日：1993-06-25
申请人： Jack Goodman
发明人： Jack Goodman
IPC分类号： G01N1/00 , B01L3/02 , B65B3/04 , G01N35/10
CPC分类号： B01L3/021 , B01L2400/0481
摘要： A liquid transfer device including a holder for a pipette array. A flexible preformed membrane having cups is over the proximal openings of the pipettes and sandwiched therebetween with a housing with the cups extending into the proximal openings of the pipettes. A vacuum drawn in the housing everts the membrane from the proximal openings thereby creating reduced pressure in the pipettes which when their distal ends are immersed in a liquid will draw up some of the liquid into the pipettes in substantially equal amounts. In one embodiment a movable abutment is provided to control the upward travel of the everting membrane and thereby the amount of liquid drawn into the pipettes. A method for fabricating the preformed membrane is also shown.
摘要翻译：一种液体输送装置，包括用于移液管阵列的保持器。具有杯的柔性预制膜在移液管的近端开口上方并且夹在其间的壳体具有杯状物延伸到移液管的近侧开口中。在壳体中抽吸的真空从近侧开口偏移膜，从而在移液管中产生减小的压力，当其远端浸入液体中时，将一些液体以基本相等的量吸入移液管中。在一个实施例中，设置可移动的邻接件以控制所述过渡膜的向上行进，从而控制吸入到移液管中的液体的量。还示出了制造预制膜的方法。

37. 发明授权

US07722632B2 Surgical suture holding device 有权
标题翻译：手术缝合保持装置
公开(公告)号：US07722632B2
公开(公告)日：2010-05-25
申请号：US10435236
申请日：2003-05-09
申请人： Paul T. Rothstein , Paul Pignato , Thomas Daigle , Jack Goodman
发明人： Paul T. Rothstein , Paul Pignato , Thomas Daigle , Jack Goodman
IPC分类号： A61B17/04
CPC分类号： A61B17/06061 , A61B17/0483 , A61B90/50 , A61B2017/0237
摘要： A device for holding a surgical suture including a base, a guide body, a cam body, a bearing member, and a spring member. The base has a top side, a front edge, and a back edge. The guide body projects from the top side of the base and defines a guide face having an entrance side and an exit side. The entrance side is adjacent the front edge and the exit side is adjacent the back edge. The cam body is pivotally mounted to the top side and forms a toothed surface positioned to selectively secure a surgical suture against the guide face. The spring member is positioned between the cam body and the bearing member, biasing the toothed surface toward the guide face.
摘要翻译：一种用于保持包括基部，引导体，凸轮体，支承构件和弹簧构件的手术缝合线的装置。底座具有顶侧，前边缘和后边缘。引导体从基部的顶侧突出并且限定具有入口侧和出口侧的引导面。入口侧邻近前缘，出口侧邻近后缘。凸轮主体枢转地安装到顶侧并形成齿形表面，其被定位成选择性地将外科缝合线固定抵靠引导面。弹簧构件定位在凸轮本体和轴承构件之间，将齿形表面朝向引导面偏置。

38. 发明申请

US20080243082A1 System for surgical drain fixation 审中-公开
标题翻译：手术排水固定系统
公开(公告)号：US20080243082A1
公开(公告)日：2008-10-02
申请号：US11731855
申请日：2007-03-30
申请人： Jack Goodman
发明人： Jack Goodman
IPC分类号： A61M27/00
CPC分类号： A61M25/02 , A61M2025/0266 , A61M2025/0273 , A61M2025/028
摘要： Devices, systems and methods for fixation of medical articles which remain in a patient's body for a period of time are provided. The articles may be secured to the patient's skin by use of a device having an arcuate channel for holding the medical article. In one device, a base member including an arcuate channel receives the medical article, which base member has a plurality of protrusions which rest against the skin providing a gap for application of a polymerizable adhesive composition which polymerizes, forming a seal around the medical article and securing the medical article to the body. Alternatively, a device including a base member having an arcuate channel is provided adhered to a flexible member. The device receives the medical article and is positioned proximate to the patient's skin. Polymerizable adhesive composition is applied to the flexible member, securing the medical article to the patient's body upon polymerization.
摘要翻译：提供了用于固定保留在患者体内一段时间的医疗用品的装置，系统和方法。可以通过使用具有用于保持医疗用品的弧形通道的装置将物品固定到患者的皮肤上。在一个装置中，包括弓形通道的基部构件接收医疗用品，该基底构件具有多个突出部，该突起部靠在皮肤上，提供用于施加可聚合的粘合剂组合物的间隙，聚合性粘合剂组合物聚合，在医疗制品周围形成密封，将医疗用品固定在身上。或者，包括具有弓形通道的基部构件的装置被附着到柔性构件。该装置接收医疗用品并且被定位成靠近患者的皮肤。可聚合的粘合剂组合物施加到柔性构件上，在聚合时将医疗制品固定到患者身上。

39. 发明申请

US20080194426A1 Flow-thru chip cartridge, chip holder, system & method thereof 审中-公开
标题翻译：流通芯片卡盘，芯片保持器及其系统及方法
公开(公告)号：US20080194426A1
公开(公告)日：2008-08-14
申请号：US12068150
申请日：2008-02-04
申请人： Jack Goodman , Matthew Torres , Hongjun Yang , David G. Mateer , Ian Stuart Richard Smith
发明人： Jack Goodman , Matthew Torres , Hongjun Yang , David G. Mateer , Ian Stuart Richard Smith
IPC分类号： C40B60/12
CPC分类号： G01N21/253 , B01L3/5027 , B01L3/502707 , B01L3/502715 , B01L3/502746 , B01L7/00 , B01L7/52 , B01L9/527 , B01L2200/027 , B01L2200/0689 , B01L2300/0636 , B01L2300/0816 , B01L2300/0877 , B01L2300/18 , B01L2300/1822 , B01L2300/1838 , B01L2400/0478 , B01L2400/0481 , B01L2400/0487 , B01L2400/06 , B01L2400/0622 , G01N21/05 , G01N2021/0346 , G01N2035/00158
摘要： A system for performing hybridization assays comprises a cartridge for housing a flow through device, where the cartridge includes a test fluid chamber for facilitating a substantially uniform flow of a test fluid mixture through the flow through device, and a fluidics station to deliver the test fluid mixture to the cartridge. The cartridge has a chip holder that holds the flow-through device, which has an array of microchannel passages. The chip holder has a support for placement of the flow though device, the test fluid chamber for directing a substantially uniform flow of a test fluid mixture through the array of microchannel passages of the flow through device, and a first port that receives the test fluid mixture. The cartridge has a sealing system for preventing the leakage of the test fluid around the flow through device. The test fluid chamber is defined in part by a spade-like surface having an inlet for the test fluid mixture.
摘要翻译：用于进行杂交测定的系统包括用于容纳流过装置的筒，其中所述筒包括用于促进测试流体混合物通过流动装置的基本均匀流动的测试流体室，以及用于输送测试流体的流体站混合到墨盒。盒具有保持流通装置的芯片保持器，该流通装置具有一组微通道通道。芯片保持器具有用于放置流通装置的支撑件，测试流体室用于引导测试流体混合物的基本上均匀的流动通过流过装置的微通道通道的阵列，以及接收测试流体的第一端口混合物。盒具有用于防止测试流体围绕流过装置的泄漏的密封系统。测试流体室部分地由具有用于测试流体混合物的入口的铲形表面限定。

40. 发明申请

US20080108878A1 Apparatus for temporarily engaging body tissue 审中-公开
标题翻译：用于临时接合身体组织的装置
公开(公告)号：US20080108878A1
公开(公告)日：2008-05-08
申请号：US12004937
申请日：2007-12-21
申请人： Jack Goodman , Tom Daigle , Douglas Gubbin , David Kim
发明人： Jack Goodman , Tom Daigle , Douglas Gubbin , David Kim
IPC分类号： A61B1/32
CPC分类号： A61B17/02 , A61B2017/00314 , A61B2017/2905 , A61B2017/306
摘要： An improved tissue engagement device such as a suction stabilizer or retractor. The stabilizer or retractor is provided with one or more suction pods mounted to the distal end of a flexible arm. The flexible arm is coupled to a base assembly, which attaches the arm to an associated retractor or other structure that is fixedly located relative to the operative site. The base assembly includes a fixed portion, which is coupled to the retractor or other fixed mounting point and a rotatable turret, allowing rotation of the arm relative to the fixed portion of the base assembly. A tensioning mechanism mounted to the turret applies tension to compress the turret around a corresponding pivot mounted to the fixed portion of the base to rotationally lock the turret and to lock the arm in its current configuration. If the device is a suction stabilizer, it may carry a spreading/tightening mechanism along with two suction pods and the tensioning mechanism may lock the relative location of the spreading/tightening mechanism relative to the arm and operate to spread the suction pods apart from one another to provide for additional stabilization at the desired anastomosis site. If the device is a suction retractor, the tensioning mechanism may lock a pivotably mounted carrier for a single enlarged suction pod so that the suction pod is held in its desired orientation relative to the arm.
摘要翻译：改进的组织接合装置，例如吸力稳定器或牵开器。稳定器或牵开器设置有一个或多个安装到柔性臂的远端的抽吸舱。柔性臂联接到基部组件，其将臂附接到相对于牵开器或相对于手术部位固定定位的其他结构。基座组件包括固定部分，该固定部分联接到牵开器或其他固定安装点以及可转动的转台，允许臂相对于基座组件的固定部分旋转。安装到转台上的张紧机构施加张力以围绕安装到基座的固定部分的相应枢轴压缩转台，以旋转地锁定转台并将臂锁定在其当前配置中。如果设备是吸力稳定器，则它可以与两个吸力舱一起携带扩张/紧固机构，并且张紧机构可以相对于手臂锁定扩张/紧固机构的相对位置，并且操作以将抽吸荚与一个另一个在所需的吻合部位提供额外的稳定。如果装置是抽吸牵开器，则张紧机构可以锁定可枢转地安装的载体以用于单个扩大的吸入舱，使得吸入舱相对于臂保持在其期望的方向。

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