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    • 31. 发明申请
    • VELOCITY MEASURING METHOD AND VELOCITY MEASURING DEVICE USING THE SAME
    • 使用相同的速度测量方法和速度测量装置
    • US20090177091A1
    • 2009-07-09
    • US11915625
    • 2006-01-06
    • Shinichiro UmemuraTakashi AzumaTetsuya HayashiNaoyuki Murayama
    • Shinichiro UmemuraTakashi AzumaTetsuya HayashiNaoyuki Murayama
    • A61B8/06
    • G01S15/8981A61B8/06A61B8/488G01S15/8977
    • The present invention is to provide a velocity measuring method and a velocity measuring device for carrying out the method. The velocity measuring method includes: a step (S4) for expanding N time series signals by using 0-th to (N−1)-th degree discrete Legendre function as a base; a step (S5) for calculating 2n-th degree complex expansion coefficient by multiplying a linear combination of a (2n−1)-th degree expansion coefficient and a (2n+1)-th degree expansion coefficient by an imaginary unit and then linearly combining the result and a 2n-th degree expansion coefficient, and calculating a (2n+1)-th degree complex expansion coefficient by multiplying the (2n+1)-th degree expansion coefficient by an imaginary unit and then linearly combining the result, the 2n-th degree expansion coefficient and a (2n+2)-th degree expansion coefficient; a degree decision step (S4) for determining the degree m of a coefficient having the maximum absolute value among the complex expansion coefficients; and a step (S8) for calculating a signed velocity signal concerning a moving reflection object from a ratio of square sums of the expansion coefficients or complex expansion coefficients corresponding to the degree m.
    • 本发明提供一种用于实施该方法的速度测量方法和速度测量装置。 速度测量方法包括:通过使用第0到第(N-1)度离散勒让德函数作为基础来扩展N个时间序列信号的步骤(S4) 通过将第(2n-1)个膨胀系数和第(2n + 1)次膨胀系数的线性组合乘以虚数单位然后线性地计算2n倍复数膨胀系数的步骤(S5) 组合结果和2n度膨胀系数,并且通过将第(2n + 1)度膨胀系数乘以虚数单位然后将结果线性组合来计算第(2n + 1)度复数膨胀系数, 第2n度膨胀系数和第(2n + 2)膨胀系数; 用于确定复数展开系数中具有最大绝对值的系数的程度m的度决定步骤(S4) 以及用于根据与度数m对应的展开系数或复扩展系数的平方和的比率来计算关于移动反射物体的有符号速度信号的步骤(S8)。
    • 34. 发明申请
    • Ultrasonic imaging device
    • 超声波成像装置
    • US20060173340A1
    • 2006-08-03
    • US10546658
    • 2003-12-04
    • Shinichiro Umemura
    • Shinichiro Umemura
    • A61B8/14
    • A61B8/481G01S7/52038G01S7/52039G01S15/8963G01S15/8979
    • The present invention provides an ultrasonic imaging technique for realizing a contrast echo image having an S/N ratio sufficiently high to make a definite diagnosis on the basis of a contrast echo image by imaging an echo component scattered by a microbubble contrast medium and a tissue harmonic component generated when a transmission pulse propagates nonlinearly so that the echo component and the tissue harmonic component are clearly distinguished from each other. The invention provides an ultrasonic imaging device for transmitting/receiving ultrasonic pulses to/from a living body in which microbubbles for contrast are introduced and forming a contrast image of the inside of the living body by using the microbubble for contrast, wherein transmitting/receiving operations are performed N times (N=an integer of three or greater) by using transmission pulse waves having a common envelope signal while varying carrier waves in phase by 360°/N from one wave to another under the same transmission/reception wave focus condition, and N pieces of time-series reception echo signals (a), (b), and (c) obtained by the N times of transmitting/receiving operations are summed to obtain a summed signal (d), thereby forming the contrast image.
    • 本发明提供了一种用于实现S / N比足够高的对比度回波图像的超声成像技术,以通过对由微泡造影剂散射的回波分量进行成像和组织谐波来进行基于对比度回波图像的确定诊断 当发射脉冲非线性传播时产生的分量使得回波分量和组织谐波分量彼此清楚地区分开。 本发明提供了一种超声波成像装置,用于向生物体发送/接收超声波脉冲,其中引入了用于对比的微泡,并且通过使用用于对比的微泡形成生物体内部的对比度图像,其中发射/接收操作 通过使用具有公共包络信号的发送脉冲波,在相同的发送/接收波聚焦条件下从一个波到另一个相位相移360°/ N的载波,执行N次(N = 3或更大的整数) 并且将通过N次发送/接收操作获得的N个时间序列接收回波信号(a),(b)和(c)相加以获得加和信号(d),从而形成对比度图像。
    • 35. 发明授权
    • Method and device of synthesizing panorama image from ultrasound images
    • 从超声图像合成全景图像的方法和装置
    • US06328693B1
    • 2001-12-11
    • US09492132
    • 2000-01-27
    • Takafumi MiyatakeAkio NagasakaShinichiro Umemura
    • Takafumi MiyatakeAkio NagasakaShinichiro Umemura
    • A61B800
    • A61B8/14A61B8/463A61B8/5238G01S7/52065G01S7/52074G06T7/30G06T2207/30004
    • A cheap, very operable ultrasound diagnosing device capable of forming a panorama slice image in a real time manner is realized. The device comprises: an imaging unit 120 for converting ultrasound data obtained from a probe 200 into an image; computers (130, 140) having a shift amount detecting function of detecting a shift amount between formed images by the operation of the probe 200 and a rotation amount detecting function of detecting a rotation amount between slice images generated by the operation of the probe 200; and panorama image displaying means 150 for displaying a panorama image 151 obtained by connecting the sequence of slice images captured during diagnosis in a plane manner in accordance with the shift amount and the rotation amount detected by the computers in parallel to the motion image display. Thus, the panorama image can be formed in a real time manner from the sequence of slice images obtained by the probe. The panorama image forming state can be recognized on a display momentarily and an erroneous probe operation can be corrected.
    • 实现了能够以实时方式形成全景切片图像的便宜且非常可操作的超声诊断装置。 该装置包括:成像单元120,用于将从探针200获得的超声数据转换为图像; 具有通过探针200的操作检测形成图像之间的移动量的移位量检测功能的计算机(130,140)和检测由探针200的操作产生的切片图像之间的旋转量的旋转量检测功能; 以及全景图像显示装置150,用于显示通过根据与计算机并行地检测到的运动图像显示的移动量和旋转量,以平面方式连接在诊断期间捕获的切片图像序列而获得的全景图像151。 因此,可以从由探针获得的切片图像的序列中实时地形成全景图像。 可以立即在显示器上识别全景图像形成状态,并且可以校正错误的探针操作。
    • 36. 发明授权
    • Method for analyzing nucleic acid or protein and apparatus therefor
    • 分析核酸或蛋白质的方法及其设备
    • US5409586A
    • 1995-04-25
    • US111508
    • 1993-08-24
    • Masao KamahoriTakeshi FujitaShinichiro UmemuraTakashi Yamada
    • Masao KamahoriTakeshi FujitaShinichiro UmemuraTakashi Yamada
    • G01N27/447G01N27/26
    • G01N27/44704G01N27/44721G01N27/44743
    • Analysis of a nucleic acid samples having thousands of bases is conducted by capillary electrophoresis. The electrophoretic section is provided with a first capillary filled with an agarose gel and a second capillary filled with a polyacrylamide gel. An on-column detector is incorporated with the second capillary for optical detection. To fill a capillary with a gel, a solution is fed under high pressure from a first flow channel through a switching valve into a second flow channel connected to the capillary. To inject a sample in the capillary, a sample injector is connected to a switching valve passage, and a buffer solution is connected to the capillary through a flow channel and the switching valve. After switching the valve, the first passage is incorporated into the flow channel between the buffer solution and the capillary being filled. Then, the sample is electrokinetically injected into the capillary. When conducting genetic polymorphism by electrophoresis, temperature control elements are provided to maintain the capillary at a predetermined temperature and a DNA sample device is provided to heat the sample to a temperature higher than a disassociation temperature thereof for directly injecting the heated sample into the capillary.
    • 通过毛细管电泳分析具有数千个碱基的核酸样品。 电泳部分设置有填充有琼脂糖凝胶的第一毛细管和填充有聚丙烯酰胺凝胶的第二毛细管。 柱内检测器与第二毛细管并入,用于光学检测。 为了用凝胶填充毛细管,将溶液在高压下从第一流动通道通过切换阀进入连接到毛细管的第二流动通道。 为了在毛细管中注入样品,将样品注射器连接到切换阀通道,并且缓冲溶液通过流动通道和切换阀连接到毛细管。 在切换阀之后,第一通道被并入缓冲溶液和被填充的毛细管之间的流动通道中。 然后,将样品电动注射到毛细管中。 当通过电泳进行遗传多态性时,提供温度控制元件以将毛细管保持在预定温度,并且提供DNA样品装置以将样品加热到高于其解离温度的温度,以将加热的样品直接喷射到毛细管中。
    • 39. 发明授权
    • Ultrasonic imaging apparatus
    • 超声波成像装置
    • US08388536B2
    • 2013-03-05
    • US12545975
    • 2009-08-24
    • Takashi AzumaShinichiro Umemura
    • Takashi AzumaShinichiro Umemura
    • A61B8/00
    • G01S15/8954G01S7/52022G01S7/52046G01S15/104G01S15/8959G01S15/8961
    • In an ultrasonic contrast imaging method in which signals specific to a contrast agent are extracted to form an image, imaging is performed with the following three well-balanced properties: frame rate, spatial resolution, and contrast-agent selectivity. A first chirp signal whose frequency increases with time and a second chirp signal obtained by inverting the first chirp signal about the time axis are used, and they are individually transmitted and received. A decoder having decode filters each adapted for a coded sequence, which is obtained when the chirp signal is decomposed into a pulse signal and a coded sequence, is provided. The decode filters are adapted for echo signals received in response to two chirp signals, respectively, and outputs of the two decode filters are input to a subtractor, whereby the difference therebetween is determined. Thus, contrast-agent selectivity is balanced with spatial resolution.
    • 在提取特定于造影剂的信号以形成图像的超声波对比度成像方法中,使用以下三个良好平衡的特性进行成像:帧速率,空间分辨率和造影剂选择性。 使用其频率随时间增加的第一啁啾信号和通过使关于时间轴的第一啁啾信号反相而获得的第二啁啾信号,并且它们被单独发送和接收。 一种具有解码滤波器的解码器,每个解码滤波器适用于当线性调频信号被分解为脉冲信号和编码序列时获得的编码序列。 解码滤波器适用于响应于两个啁啾信号而接收的回波信号,并且两个解码滤波器的输出被输入到减法器,从而确定它们之间的差异。 因此,造影剂选择性与空间分辨率平衡。