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    • 22. 发明专利
    • Method and apparatus for separating single stranded nucleic acid and microarray and dna chip
    • 分离单条核酸和微量核糖核酸切片的方法和装置
    • JP2006230342A
    • 2006-09-07
    • JP2005052896
    • 2005-02-28
    • Tokyo Univ Of Agriculture & TechnologyYokogawa Electric Corp国立大学法人東京農工大学横河電機株式会社
    • MATSUNAGA TADASHITAKEYAMA HARUKOTANAKA TAKESHITANAAMI TAKEOSATO SAAYAKATAKURA HISAOMIMORI YUJISHIGEKI GOSUKE
    • C12N15/09C12M1/00G01N33/53G01N37/00
    • C12N15/1006C12Q1/6806C12Q1/6837C12Q2563/131C12Q2523/113
    • PROBLEM TO BE SOLVED: To provide a technique by which a single stranded nucleic acid used on genetic information analyses can simply be provided in a short time.
      SOLUTION: This method for separating the single stranded nucleic acid is characterized by amplifying a nucleic acid with the second substance-bound first primer capable of being specifically bound to the first substance and the second substance-non-bounded second primer, binding the double stranded nucleic acid obtained by the nucleic acid amplification to the first substance, and then dissociating the first substance-bound double stranded nucleic acid into the single stranded nucleic acid. And, the apparatus for separating the single stranded nucleic acid is characterized by having the second substance-bound first primer capable of being specifically bound to the first substance, a nucleic acid-amplifying portion 1 for amplifying the nucleic acid with the second substance-non-bound second primer, a binding portion 2 for binding the double stranded nucleic acid obtained by the nucleic acid amplification to the first substance, and a dissociating portion 3 for dissociating the first substance-bound double stranded nucleic acid into the single stranded nucleic acid.
      COPYRIGHT: (C)2006,JPO&NCIPI
    • 要解决的问题:提供在短时间内可以简单地提供用于遗传信息分析的单链核酸的技术。 解决方案:用于分离单链核酸的方法的特征在于用能够与第一物质和第二物质无界第二引物特异性结合的第二物质结合的第一引物扩增核酸,结合 通过对第一物质进行核酸扩增获得的双链核酸,然后将第一物质结合的双链核酸解离成单链核酸。 并且,用于分离单链核酸的装置的特征在于具有能够与第一物质特异性结合的第二物质结合的第一引物,用于扩增具有第二物质非核酸的核酸的核酸扩增部分1 用于将通过核酸扩增获得的双链核酸与第一物质结合的结合部分2和用于将第一物质结合的双链核酸解离成单链核酸的解离部分3。 版权所有(C)2006,JPO&NCIPI
    • 23. 发明专利
    • Biochip producing device
    • 生物制造设备
    • JP2006078382A
    • 2006-03-23
    • JP2004263727
    • 2004-09-10
    • Yokogawa Electric Corp横河電機株式会社
    • TANAAMI TAKEOSATO SAAYA
    • G01N33/53G01N1/00G01N37/00
    • B01L3/0258B01J19/0046B01J2219/00382B01J2219/00533B01J2219/00659B01J2219/0072B01L3/5085
    • PROBLEM TO BE SOLVED: To provide a biochip producing device that can shorten a biochip producing period, prevents mixing of different kinds of biopolymer solutions, and can easily obtain a uniform site.
      SOLUTION: The biochip producing device for arranging many different biopolymers on a substrate of the biochip comprises a support body movable in any direction, an integrally constituted stamp attached to the support body, and a biopolymer solution feeder for feeding two or more kinds of different biopolymer solutions adhering to the stamp tip. The biopolymer solutions are stuck to the stamp tip from the biopolymer solution feeder, and the stamp is pressed onto the substrate of the biochip, thereby sticking the biopolymer solutions to the substrate surface of the biochip in the arrangement same as that of the stamp to simultaneously form a plurality of sites.
      COPYRIGHT: (C)2006,JPO&NCIPI
    • 要解决的问题:提供可以缩短生物芯片生产周期的生物芯片生产装置,防止不同种类的生物聚合物溶液的混合,并且可以容易地获得均匀的部位。 解决方案:用于在生物芯片的基底上排列许多不同的生物聚合物的生物芯片生产装置包括可沿任何方向移动的支撑体,附着在支撑体上的整体构造的印模,以及用于输送两种或更多种的生物聚合物溶液进料器 不同的生物聚合物溶液附着在印章上。 将生物聚合物溶液从生物聚合物溶液进料器粘附到印模尖端,并将印模压在生物芯片的基底上,从而将生物聚合物溶液粘贴到生物芯片的基底表面上,同时与印模相同 形成多个站点。 版权所有(C)2006,JPO&NCIPI
    • 26. 发明专利
    • Cartridge system for chemical reaction
    • 化学反应盒系统
    • JP2010060574A
    • 2010-03-18
    • JP2009282795
    • 2009-12-14
    • Yokogawa Electric Corp横河電機株式会社
    • TANAAMI TAKEOKATAKURA HISAOSATO SAAYA
    • G01N35/10C12M1/00G01N33/53G01N37/00
    • PROBLEM TO BE SOLVED: To provide a compact cartridge system for chemical reaction detecting a target molecule using a chip for target molecule detection and efficiently detecting the target molecule. SOLUTION: The cartridge system for chemical reaction has a cartridge for chemical reaction forming chambers for containing a solution and a flow channel connecting these chambers by partly adhering a base plate to an elastic member, and a roller which applies external force to the cartridge for chemical reaction and delivers internal liquid by deformation of the cartridge for chemical reaction. The system is provided with a containing part formed inside the cartridge for chemical reaction as a chamber and contains the chip for target molecule detection, first and second chambers formed inside the cartridge for chemical reaction as chambers and provided in front of and in the rear of the containing part by placing it therebetween, and two rollers provided with a constant space and move in parallel with the elastic member pressed against the base plate. By reciprocating two rollers, the solution is reciprocated between the first chamber and the second chamber. COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:提供用于使用用于靶分子检测的芯片和有效检测靶分子来检测靶分子的化学反应的紧凑的盒系统。 解决方案:用于化学反应的药筒系统具有用于容纳溶液的化学反应形成室的药筒和通过将基板部分地粘附到弹性部件而连接这些腔室的流动通道,以及向外界施加外力的辊 用于化学反应的墨盒,并通过墨盒的化学反应产生内部液体。 该系统设置有形成在用于化学反应的盒中的容纳部分作为室,并且包含用于靶分子检测的芯片,形成在用于化学反应的盒作为室内的第一和第二室,并且设置在 容纳部分通过放置在其间,以及设置有恒定空间并与弹性构件平行移动的两个辊压靠在基板上。 通过往复运动两个辊,溶液在第一室和第二室之间往复运动。 版权所有(C)2010,JPO&INPIT
    • 27. 发明专利
    • Method and device for evaluating characteristics of battery
    • 用于评估电池特性的方法和装置
    • JP2010048567A
    • 2010-03-04
    • JP2008210524
    • 2008-08-19
    • Yokogawa Electric Corp横河電機株式会社
    • TOMOSADA NOBUHIROYAMAZAKI DAISUKEKIMURA ATSUSHIKAWANO MAKOTOSATO SAAYAAKUTSU TOMOMI
    • G01R31/00H01M8/04H01M8/10
    • Y02E60/521
    • PROBLEM TO BE SOLVED: To provide a method and a device for evaluating characteristics of a battery, capable of efficiently obtaining current-voltage characteristics, and the like, from measurements with fewer measurement points.
      SOLUTION: An operating point switching means 61 sequentially changes a DC-like operating point of the battery. An impedance obtaining means 62 obtains the value of resistance, constituting the battery at the operating point, on the basis of the results of the measurement performing the impedance measurement with the superimposition of AC components under the DC-like operating point currently selected by the operating point switching means 61. A current-voltage characteristics obtaining means 63 obtains discrete current-voltage characteristics at the measurement part in the DC-like operating point. A current-voltage characteristics interpolation means 64 interpolates the current-voltage characteristics between the adjacent operating points, on the basis of the value of resistance obtained by the impedance obtaining means 62 for the current-voltage characteristics obtained by the current-voltage characteristics obtaining means 63.
      COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:提供一种用于评估电池特性的方法和装置,其能够从具有较少测量点的测量中有效地获得电流 - 电压特性等。 解决方案:工作点切换装置61顺序地改变电池的类DC工作点。 阻抗获取装置62基于通过操作当前选择的类似DC的工作点处的AC分量的叠加来执行阻抗测量的测量结果,获得在工作点构成电池的电阻值 电流 - 电压特性获得装置63在类似DC的工作点的测量部分获得离散的电流 - 电压特性。 电流 - 电压特性插值装置64基于由电流 - 电压特性获得装置获得的电流 - 电压特性由阻抗获得装置62获得的电阻值来内插相邻工作点之间的电流 - 电压特性 (C)2010年,JPO&INPIT
    • 29. 发明专利
    • Characteristic evaluation method and characteristic evaluation device for fuel cell
    • 燃料电池的特征评估方法和特征评估装置
    • JP2009134924A
    • 2009-06-18
    • JP2007308693
    • 2007-11-29
    • Yokogawa Electric Corp横河電機株式会社
    • TOMOSADA NOBUHIROYAMAZAKI DAISUKEKIMURA ATSUSHISHINTANI YUKIHIROAKUTSU TOMOMISATO SAAYA
    • H01M8/04H01M8/10
    • Y02E60/521
    • PROBLEM TO BE SOLVED: To provide a characteristic evaluation method and a characteristic evaluation device for a fuel cell, capable of accurately evaluating the fuel cell by using an equivalent circuit model suitably showing electric impedance of the fuel cell.
      SOLUTION: As for a plurality of equivalent circuit models having mutually different structures, a step of evaluating appropriateness for application of the equivalent circuit model and a step of modelling the fuel cell by fitting a circuit constant of the appropriate equivalent circuit model obtained by the step of evaluating its appropriateness are provided in the characteristic evaluation method. The step of evaluating its appropriateness evaluates appropriateness of the equivalent circuit model by using suitability for fitting of individual equivalent circuit model and the maximum value of element errors. Furthermore, the appropriateness of a combination of the equivalent circuit models corresponding to electric impedance characteristics of a unit cell, an anode and a cathode of the fuel cell is evaluated on the basis of relationship existed between these electric impedance characteristics.
      COPYRIGHT: (C)2009,JPO&INPIT
    • 要解决的问题:为了提供一种能够通过使用适当地示出燃料电池的电阻抗的等效电路模型来精确地评估燃料电池的燃料电池的特性评估方法和特性评估装置。 解决方案:对于具有相互不同结构的多个等效电路模型,评估适用于等效电路模型的步骤和通过拟合所获得的适当的等效电路模型的电路常数对燃料电池进行建模的步骤 通过评价其适用性的步骤在特征评价方法中提供。 评估其适当性的步骤通过使用适用于各个等效电路模型的拟合和元件误差的最大值来评估等效电路模型的适用性。 此外,基于这些电阻抗特性之间的关系来评估对应于燃料电池的单电池,阳极和阴极的电阻抗特性的等效电路模型的组合的适当性。 版权所有(C)2009,JPO&INPIT