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21. 发明授权

US4418140A Process for the development of color photographic light-sensitive material 失效
标题翻译：彩色摄影感光材料的开发工艺
公开(公告)号：US4418140A
公开(公告)日：1983-11-29
申请号：US366515
申请日：1982-04-08
申请人： Hiroyuki Mifune , Shoji Ishiguro , Tadao Shishido , Tatsuo Nishimura
发明人： Hiroyuki Mifune , Shoji Ishiguro , Tadao Shishido , Tatsuo Nishimura
IPC分类号： G03C7/26 , C07D257/04 , G03C7/30 , G03C7/392 , G03C7/00
CPC分类号： C07D257/04 , G03C7/3926 , Y02P20/55
摘要： A process for the development of color photographic light-sensitive material is described. The process comprises color developing an exposed light-sensitive material in the presence of a compound of the general formula: ##STR1## wherein M is a hydrogen atom, an alkali metal atom, NH.sub.4 or a protective group for the mercapto group which undergoes cleavage by the action of an alkali; R is a hydrogen atom or an alkyl group containing 1 to 3 carbon atoms; and R' is a hydrogen atom or an alkyl group containing 1 to 3 carbon atoms. This process prevents the formation of color development fog without seriously reducing sensitivity.
摘要翻译：描述了彩色照相感光材料的开发方法。该方法包括在下列通式的化合物存在下显色曝光的感光材料：其中M是氢原子，碱金属原子，NH 4或巯基的保护基，其通过碱的作用; R是氢原子或含有1至3个碳原子的烷基; 并且R'是氢原子或含有1至3个碳原子的烷基。该过程防止形成颜色发展，而不会严重降低灵敏度。

22. 发明授权

US4200575A 7[(2-Thiazolyl)-2-(oxoimino)acetamido]cephalosporin derivatives 失效
标题翻译： 7 [（2-噻唑基）-2-（氧代亚氨基）乙酰氨基]头孢菌素衍生物
公开(公告)号：US4200575A
公开(公告)日：1980-04-29
申请号：US930041
申请日：1978-08-01
申请人： Mitsuo Numata , Tatsuo Nishimura
发明人： Mitsuo Numata , Tatsuo Nishimura
IPC分类号： A61K31/545 , A61K31/546 , A61P31/04 , C07D501/20 , C07D501/22 , C07D501/24 , C07D501/34 , C07D501/36 , C07D501/46
CPC分类号： C07D501/20
摘要： Novel [2-(syn)-carbamoyloximinoacetamido]cephalosporins of the formula: ##STR1## [wherein, Y.sup.1 is hydrogen, hydroxyl, carbamoyloxy, acyloxy, quaternary ammonium or nitrogen-containing heterocyclic thio; R.sup.1 is alkyl, aralkyl or aryl; R.sup.2 is hydrogen or an ester residue; k is 0 or 1] and a salt thereof show strong antibacterial activities particularly against Gram-negative bacteria and they are useful as antibacterial agents.
摘要翻译：具有下式的新型[2-（顺式） - 氨基甲酰亚氨基乙酰胺基]头孢菌素其中Y1是氢，羟基，氨基甲酰氧基，酰氧基，季铵或含氮杂环硫基; R1是烷基，芳烷基或芳基; R2是氢或酯残基; k为0或1]，其盐对革兰氏阴性菌具有强的抗菌活性，可用作抗菌剂。

23. 发明授权

US5120841A Cephalosporin ester derivatives 失效
标题翻译： CEPHALOSPORIN ESTER衍生物
公开(公告)号：US5120841A
公开(公告)日：1992-06-09
申请号：US027433
申请日：1987-03-18
申请人： Tatsuo Nishimura , Yoshinobu Yoshimura , Mitsuo Numata
发明人： Tatsuo Nishimura , Yoshinobu Yoshimura , Mitsuo Numata
IPC分类号： C07D501/36 , A61K31/54 , A61K31/545 , A61K31/546 , A61P31/04 , C07C67/08 , C07D20060101 , C07D257/04 , C07D277/22 , C07D499/42 , C07D501/00 , C07D501/02 , C07D501/04 , C07D501/20 , C07D501/34 , C07D501/46 , C07D501/56
CPC分类号： C07D501/36
摘要： A compound of the formula: ##STR1## wherein R.sub.1 is a hydrogen atom or a lower alkyl group; R.sub.2 is an unsubstituted or lower alkyl-substituted alicyclic alkyl group of 3 to 12 carbon atoms or a C.sub.3-6 alicyclic alkyl-substituted lower alkyl group or a pharmaceutically acceptable salt thereof, processes for preparing the same, a pharmaceutical composition thereof are provided. The compound has an improved absorbability and can be orally applied as antibiotics.
摘要翻译：下式的化合物：其中R 1是氢原子或低级烷基; R2是3-12个碳原子的未取代或低级烷基取代的脂环族烷基或C3-6脂环族烷基取代的低级烷基或其药学上可接受的盐，其制备方法，其药物组合物。该化合物具有改善的吸收性，可作为抗生素口服使用。

24. 发明授权

US4760308A Electron gun for color picture tubes 失效
标题翻译：电子枪彩色显像管
公开(公告)号：US4760308A
公开(公告)日：1988-07-26
申请号：US307572
申请日：1981-10-01
申请人： Shoji Shirai , Masaaki Yamauchi , Hiroshi Takano , Masakazu Fukushima , Tatsuo Nishimura
发明人： Shoji Shirai , Masaaki Yamauchi , Hiroshi Takano , Masakazu Fukushima , Tatsuo Nishimura
IPC分类号： H01J29/50 , H01J29/51 , H01J29/62
CPC分类号： H01J29/50 , H01J29/51
摘要： An electron gun for a color picture tube has beam generators for generating three electron beams and directing them toward the fluorescent screen along three paths which are parallel with each other on the same plane, and at least one pair of electrode surfaces each having three apertures centered with the three paths for forming independent main lenses so as to focus the electron beams on the fluorescent screen, the electrode surfaces being spaced apart from each other. Provided for the electrode surface are cylindrical shield members centered with the apertures and extending from the apertures in opposition to the opposing electrode surface. Outer ones of the cylindrical shield members have each an end surface inclined with respect to the center axis of the aperture so as to form inclined electric fields effective to converge the outer beams to one point to which the central beam converges.
摘要翻译：用于彩色显像管的电子枪具有用于产生三束电子束的光束发生器，并且沿着在相同平面上彼此平行的三条路径将荧光屏导向荧光屏，并且至少一对电极表面各自具有三个孔利用形成独立的主透镜的三条路径以将电子束聚焦在荧光屏上，电极表面彼此间隔开。为电极表面提供的是圆柱形屏蔽构件，其与孔对中并且从孔开始相对于相对的电极表面延伸。圆柱形屏蔽构件中的另外一个具有相对于孔的中心轴线倾斜的端面，以便形成有效地将外梁会聚到中心束会聚到一点的倾斜电场。

25. 发明授权

US4729992A Cephalosporin esters, their production and use 失效
标题翻译：头孢菌素酯，其生产和使用
公开(公告)号：US4729992A
公开(公告)日：1988-03-08
申请号：US724927
申请日：1985-04-19
申请人： Tatsuo Nishimura , Yoshinobu Yoshimura , Mitsuo Numata
发明人： Tatsuo Nishimura , Yoshinobu Yoshimura , Mitsuo Numata
IPC分类号： A61K31/545 , A61K31/546 , A61P31/04 , C07D501/36
CPC分类号： C07D501/36
摘要： A compound of the formula: ##STR1## or a pharmaceutical acceptable salt thereof, processes for preparing the same and a pharmaceutical composition containing the compound or the salt thereof mentioned above are provided. The compound has antibiotic activity and has improved absorbability.
摘要翻译：提供下式的化合物或其药学上可接受的盐，其制备方法和含有上述化合物或其盐的药物组合物。该化合物具有抗菌活性并具有改善的吸收性。

26. 发明授权

US4328302A Lithographic silver halide photographic light-sensitive material 失效
标题翻译：平版印刷卤化银照相感光材料
公开(公告)号：US4328302A
公开(公告)日：1982-05-04
申请号：US232483
申请日：1981-02-09
申请人： Tatsuo Nishimura , Hiroyuki Mifune , Yoshiharu Fuseya , Yukihide Urata , Tadao Shishido , Yasuo Kasama
发明人： Tatsuo Nishimura , Hiroyuki Mifune , Yoshiharu Fuseya , Yukihide Urata , Tadao Shishido , Yasuo Kasama
IPC分类号： G03C1/06 , C07D257/04 , G03C1/35
CPC分类号： C07D257/04 , G03C1/355 , Y10S430/15
摘要： A lithographic silver halide photographic light-sensitive material is described which scarcely exhibits colored fringe and black pepper, forms halftone dots of good quality whether a fresh or an exhausted developer is used for processing thereof, and which scarcely shows a drop in sensitivity even when a developer contaminated by a fixing solution is used; said material comprises a support and at least one lithographic silver halide emulsion layer, and containing in said emulsion layer or in another hydrophilic colliodal layer which does not contain silver halide emulsion at least one compound represented by formula (I) ##STR1## wherein M represents hydrogen, an alkali metal ion or --NH.sub.4.sup..sym. ; X represents --SO.sub.2 NHR', --COOM', --SO.sub.3 M', --OH or --CONH.sub.2, wherein M' represents hydrogen, an alkali metal ion or --NH.sub.4.sup..sym. ; and R' represents hydrogen or an alkyl group having from 1 to 3 carbon atoms; R represents hydrogen or an alkyl group having from 1 to 3 carbon atoms; and n represents 1 or 2.
摘要翻译：描述了几乎不显示有色边缘和黑胡椒的平版卤化银照相感光材料，即使使用新鲜或耗尽的显影剂进行处理，也形成质量好的半色调点，并且即使当使用受固定液污染的显影剂; 所述材料包括载体和至少一个平版卤化银乳剂层，并且在所述乳剂层中或在不含有卤化银乳剂的另一亲水性乳液层中包含至少一种由式（I）表示的化合物（I）其中M表示氢，碱金属离子或-NH4（+）; X表示-SO 2 NHR'，-COOM'，-SO 3 M'，-OH或-CONH 2，其中M'表示氢，碱金属离子或-NH 4（+）。并且R'表示氢或具有1至3个碳原子的烷基; R表示氢或具有1至3个碳原子的烷基; n表示1或2。

27. 发明授权

US4239758A Cephalosporins 失效
标题翻译：头孢菌素
公开(公告)号：US4239758A
公开(公告)日：1980-12-16
申请号：US44215
申请日：1979-05-31
申请人： Mitsuo Numata , Masayoshi Yamaoka , Isao Minamida , Mitsuru Shiraishi , Tatsuo Nishimura
发明人： Mitsuo Numata , Masayoshi Yamaoka , Isao Minamida , Mitsuru Shiraishi , Tatsuo Nishimura
IPC分类号： A61K20060101 , A61K31/545 , A61K31/546 , A61P31/04 , C07D20060101 , C07D501/00 , C07D501/04 , C07D501/20 , C07D501/22 , C07D501/24 , C07D501/26 , C07D501/28 , C07D501/34 , C07D501/36 , C07D501/38 , C07D501/46 , C07D501/56 , C07D501/60
CPC分类号： C07D501/20 , C07D501/24
摘要： A novel cephalosporin derivative of the formula: ##STR1## [wherein X is hydrogen, hydroxyl, acyloxy, alkoxy, carbamoyloxy, quaternary ammonium or a group of the formula --SR.sup.1 (where R.sup.1 is a nitrogen-containing heterocyclic group)] or a pharmaceutically acceptable salt or ester thereof is found to have potent antibiotic activity against various bacteria, particularly against gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Proteus mirabilis, Proteus morganii, Proteus rettgeri and Citrobacter freundii.
摘要翻译：一种下式的新型头孢菌素衍生物：其中X是氢，羟基，酰氧基，烷氧基，氨基甲酰氧基，季铵或式-SR1（其中R1是含氮杂环基）的基团）或药学上发现其可接受的盐或酯对各种细菌，特别是对革兰氏阴性细菌如大肠杆菌，肺炎克雷伯杆菌，普通变形杆菌，奇异变形杆菌，变形杆菌，变形杆菌和弗氏氟柠檬酸杆菌具有有效的抗生素活性。

28. 发明授权

US4172891A Cephalosporins 失效
标题翻译：头孢菌素
公开(公告)号：US4172891A
公开(公告)日：1979-10-30
申请号：US783230
申请日：1977-03-31
申请人： Mitsuo Numata , Masayoshi Yamaoka , Isao Minamida , Mitsuru Shiraishi , Tatsuo Nishimura
发明人： Mitsuo Numata , Masayoshi Yamaoka , Isao Minamida , Mitsuru Shiraishi , Tatsuo Nishimura
IPC分类号： A61K20060101 , A61K31/545 , A61K31/546 , A61P31/04 , C07D20060101 , C07D501/00 , C07D501/04 , C07D501/20 , C07D501/22 , C07D501/24 , C07D501/26 , C07D501/28 , C07D501/34 , C07D501/36 , C07D501/38 , C07D501/46 , C07D501/56 , C07D501/60
CPC分类号： C07D501/20 , C07D501/24
摘要： A novel cephalosporin derivative of the formula: ##STR1## [wherein X is hydrogen, hydroxyl, acyloxy, alkoxy, carbamoyloxy, quaternary ammonium or a group of the formula --SR.sup.1 (where R.sup.1 is a nitrogen-containing heterocyclic group)] or a pharmaceutically acceptable salt or ester thereof is found to have potent antibiotic activity against various bacteria, particularly against gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Proteus mirabilis, Proteus morganii, Proteus rettgeri and Citrobacter freundii.
摘要翻译：一种下式的新型头孢菌素衍生物：其中X是氢，羟基，酰氧基，烷氧基，氨基甲酰氧基，季铵或式-SR1（其中R1是含氮杂环基）的基团）或药学上发现其可接受的盐或酯对各种细菌，特别是对革兰氏阴性细菌如大肠杆菌，肺炎克雷伯杆菌，普通变形杆菌，奇异变形杆菌，变形杆菌，变形杆菌和弗氏氟柠檬酸杆菌具有有效的抗生素活性。

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