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    • 24. 发明授权
    • Container for accommodating optical fiber coil and optical fiber module having the container
    • 用于容纳光纤线圈的容器和具有容器的光纤模块
    • US07548679B2
    • 2009-06-16
    • US11923269
    • 2007-10-24
    • Masaaki HiranoMasahiro YamaguchiMasaki Tsuruga
    • Masaaki HiranoMasahiro YamaguchiMasaki Tsuruga
    • G02B6/00
    • G02B6/4457
    • A container for an optical fiber coil and an optical fiber module including the container is provided, wherein an excess length portion of a pigtail fiber is accommodated in the container and the remaining portion can be drawn out from the container. The container includes a first part for accommodating a coil having a functional optical fiber, and a second part disposed on an outer periphery side of the first part and windingly accommodating a pigtail fiber that is optically connected to the functional optical fiber. The second part has a gap that extends over the entirety of the outer periphery, and communicates with the exterior. The optical fiber module includes the container, the coil having the functional optical fiber accommodated in the first part of the container, and the pigtail fiber that is optically connected to the functional fiber and that has a portion windingly accommodated in the second part.
    • 提供了一种用于光纤线圈的容器和包括容器的光纤模块,其中猪尾纤维的多余长度部分容纳在容器中,其余部分可以从容器中抽出。 容器包括用于容纳具有功能光纤的线圈的第一部分和设置在第一部分的外周侧上的第二部分,并且卷绕容纳与功能光纤光学连接的引出纤维。 第二部分具有在整个外周上延伸并与外部连通的间隙。 光纤模块包括容器,具有容纳在容器的第一部分中的功能光纤的线圈和光纤连接到功能性光纤并且具有卷绕在第二部分中的部分的尾纤光纤。
    • 30. 发明授权
    • Recombinant lysophosphatidic acid phosphatase
    • 重组溶血磷脂酸性磷酸酶
    • US06472193B1
    • 2002-10-29
    • US09600588
    • 2000-09-11
    • Tadaomi TakenawaMasami HiroyamaTatsuya KishimotoMasahiro YamaguchiMitsuyoshi ToyosatoKouji Mizuno
    • Tadaomi TakenawaMasami HiroyamaTatsuya KishimotoMasahiro YamaguchiMitsuyoshi ToyosatoKouji Mizuno
    • C12N914
    • C12N9/16C12Q1/42
    • An object of the present invention is to provide a recombinant LPA phosphates capable of specifically hydrolyzing LPA, which is useful for elucidation of the metabolic pathway of LPA, and also for diagnosis and treatment of various diseases with which LPA is associated. The present invention also provides for a method capable of simply and inexpensively determining LPA associated with various diseases. The present invention also provides for a kit for determination suitable for the method. The present invention has succeeded in purifying the LPA phosphatase using bovine brain as a raw material, and further in cloning human LPA phosphatase gene. The present invention specifically relates to a DNA encoding a peptide comprising the amino acid sequence of SEQ ID NO:1; a DNA comprising the nucleotide sequence of SEQ ID NO:2; a protein encoded by the DNA; and expression vector carrying the DNA; a transformant harboring the expression vector; a method for producing a recombinant lysophosphatidic acid phosphatase by the transformant; a method for determination of LPA by the protein; a determination reagent for LPA by the protein; a kit for diagnosis, comprising the reagent for determination, and the like.
    • 本发明的目的是提供能够特异性水解LPA的重组LPA磷酸酯,其可用于阐明LPA的代谢途径,以及用于诊断和治疗与LPA相关的各种疾病。 本发明还提供了能够简单且廉价地确定与各种疾病相关的LPA的方法。 本发明还提供了适用于该方法的用于测定的试剂盒。 本发明成功地使用牛脑作为原料来纯化LPA磷酸酶,进一步克隆人类LPA磷酸酶基因。 本发明具体涉及编码包含SEQ ID NO:1的氨基酸序列的肽的DNA; 包含SEQ ID NO:2的核苷酸序列的DNA; 由DNA编码的蛋白质; 和携带DNA的表达载体; 携带表达载体的转化体; 由转化体生产重组溶血磷脂酸性磷酸酶的方法; 一种由蛋白质测定LPA的方法; 用于蛋白质的LPA的测定试剂; 用于诊断的试剂盒,包括用于测定的试剂等。