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21. 发明申请

US20090291153A1 Health food, Method for producing the same and dried Product and Extract 审中-公开
标题翻译：保健食品，生产方法和干燥产品和提取物
公开(公告)号：US20090291153A1
公开(公告)日：2009-11-26
申请号：US10577328
申请日：2005-04-14
申请人： Kazuo Umezawa , Izumi Takei , Seiji Shibahara , Itaru Kojima , Takashi Koyano , Chika Ishii
发明人： Kazuo Umezawa , Izumi Takei , Seiji Shibahara , Itaru Kojima , Takashi Koyano , Chika Ishii
IPC分类号： A61K36/24 , A61P3/10
CPC分类号： A61K31/455 , A23L33/105 , A23V2002/00 , A61K36/24 , A23V2250/21 , A23V2200/328
摘要： Conophylline, contained in leaves of Ervatamia microphylla or Tabernaemontana divaricata, can induce non-tumor cells to differentiate into insulin-producing cells and thereby to produce insulin and also to lower blood glucose levels. Thus, in the present invention, dried products and extracts of leaves of Ervatamia microphylla or Tabernaemontana divaricata, which contain conophylline, are used as health foods for preventing and improving diabetes and obesity or health foods for lowering blood glucose levels.
摘要翻译：茶叶中含有的叶绿素（Ervatamia microphylla）或Tabernaemontana divaricata，可诱导非肿瘤细胞分化成胰岛素生成细胞，从而产生胰岛素，降低血糖水平。因此，本发明中，作为防止和改善用于降低血糖水平的糖尿病和肥胖症或健康食品的健康食品，使用干燥产品和含有茶碱的小叶螨的叶子的提取物或者Tabernaemontana divaricata的叶子提取物。

22. 发明申请

US20080106689A1 Display Element And Display Device 审中-公开
标题翻译：显示元件和显示设备
公开(公告)号：US20080106689A1
公开(公告)日：2008-05-08
申请号：US10574505
申请日：2005-08-24
申请人： Iichiro Inoue , Seiji Shibahara , Koichi Miyachi , Shoichi Ishihara
发明人： Iichiro Inoue , Seiji Shibahara , Koichi Miyachi , Shoichi Ishihara
IPC分类号： C09K19/02
CPC分类号： G02F1/1393 , C09K19/22 , C09K19/24 , C09K19/3028 , C09K19/3068 , C09K19/3444 , C09K2019/0407 , C09K2019/0481 , C09K2019/3027 , G02F1/1334 , G02F1/13731 , G02F1/139
摘要： A display element of the present invention includes: a pair of substrates which are opposed to each other; and a substance layer, which is sandwiched between the substrates, exhibiting an optical isotropy when no electric field is applied, while exhibiting an optical anisotropy when an electric field is applied, and the display element performs display operation by applying an electric field to between the substrates. The substance layer includes a liquid crystalline medium exhibiting a nematic liquid crystal phase, and it is Δn×|Δ∈|≧1.9, where Δn is a refractive index anisotropy at 550 nm in a nematic phase of the liquid crystalline medium, and |Δ∈| is an absolute value of a dielectric anisotropy at 1 kHz in the nematic phase of the liquid crystalline medium. The display element and a display device including the display element realize a fast response speed and a low driving voltage and driving in a wide temperature range.
摘要翻译：本发明的显示元件包括：一对彼此相对的基板; 以及夹在基板之间的物质层，当没有施加电场时呈现光学各向同性，同时当施加电场时呈现光学各向异性，并且显示元件通过施加电场来进行显示操作底物。物质层包括显示向列型液晶相的液晶介质，它是Deltanx |Δε|> = 1.9，其中Deltan是在液晶介质的向列相中的550nm处的折射率各向异性，| Delta ∈| 是在液晶介质的向列相中1kHz的介电各向异性的绝对值。显示元件和包括显示元件的显示装置实现快速响应速度和低驱动电压并在宽温度范围内驱动。

23. 发明授权

US5631257A Benzoxazole derivatives 失效
标题翻译：苯并恶唑衍生物
公开(公告)号：US5631257A
公开(公告)日：1997-05-20
申请号：US487697
申请日：1995-06-07
申请人： Katsuyoshi Iwamatsu , Yasuo Sato , Masaaki Izumi , Fukio Konno , Seiji Shibahara , Shigeharu Inoye , Koichi Shudo , Kazuko Amano
发明人： Katsuyoshi Iwamatsu , Yasuo Sato , Masaaki Izumi , Fukio Konno , Seiji Shibahara , Shigeharu Inoye , Koichi Shudo , Kazuko Amano
IPC分类号： A61K31/42 , A61K31/423 , A61K31/495 , A61K31/496 , A61K31/55 , A61P1/00 , A61P1/08 , A61P1/14 , A61P25/04 , A61P25/18 , A61P25/20 , A61P25/22 , A61P43/00 , C07D263/58 , C07D263/60 , C07D487/10 , C07D401/00 , C07D419/00
CPC分类号： C07D263/58 , C07D263/60 , C07D487/10
摘要： A benzoxazole derivative of the formula (1) or (2) which has an alicyclic diamine group at the 2-position: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, X.sup.-, m and n are defined herein. The compound shows excellent 5-HT.sub.3 receptor antagonism and is useful as an antiemetic agent, a peristalsis controlling agent, an analgesic agent, an antianxiety agent and a schizophrenia treating agent.
摘要翻译：（2）中具有脂环族二胺基团的式（1）或（2）的苯并恶唑衍生物：其中R1，R2，R3，R4，R5，R6， X，m和n在本文中定义。该化合物显示优异的5-HT 3受体拮抗作用，可用作止吐剂，蠕动控制剂，止痛剂，抗焦虑剂和精神分裂症治疗剂。

24. 发明授权

US5618795A Dibekacin derivatives and arbekacin derivatives active against resistant bacteria, and the production thereof 失效
标题翻译：对抗性细菌有活性的二比卡星衍生物和阿贝卡星衍生物及其生产
公开(公告)号：US5618795A
公开(公告)日：1997-04-08
申请号：US524644
申请日：1995-09-08
申请人： Shinichi Kondo , Seiji Shibahara , Takayuki Usui , Toshiaki Kudo , Shuichi Gomi , Atsushi Tamura , Yoko Ikeda , Daishiro Ikeda , Tomio Takeuchi
发明人： Shinichi Kondo , Seiji Shibahara , Takayuki Usui , Toshiaki Kudo , Shuichi Gomi , Atsushi Tamura , Yoko Ikeda , Daishiro Ikeda , Tomio Takeuchi
IPC分类号： C07H15/236 , A61K31/70
CPC分类号： C07H15/234
摘要： As new dibekacin derivatives and new arbekacin derivatives are now provided 2"-amino-2"-deoxydibekacin, 2"-amino-5,2"-dideoxydibekacin, 2"-amino-2"-deoxyarbekacin, 2"-amino-5,2"-dideoxyarbekacin, 2"-amino-5,2"-dideoxy-5-epi-fluoroarbekacin and 2"-amino-5,2"-dideoxy-5-epi-aminoarbekacin which all exhibit high antibacterial activity against a wide variety of gram-positive and gram-negative bacteria, including resistant bacteria such as methicillin-resistant Staphylococcus aureus and which are of low toxicity to mammals and are useful as antibacterial agent for treatment of bacterial infections.
摘要翻译：现在提供新的二卡辛衍生物和新的阿贝卡星衍生物2' - 氨基-2' - 脱氧胆碱，2“ - 氨基-5,2” - 脱氧胆酸，2“ - 氨基-2'-脱氧阿糖胞苷，2 “ - 氨基-5,2” - 双脱氧肉豆蔻素，2“ - 氨基-5,2” - 双脱氧-5-表 - 氟代贝卡星和2“ - 氨基-5,2” - 双脱氧-5-表所有这些都表现出对各种革兰氏阳性和革兰氏阴性细菌的高抗菌活性，包括耐甲氧西林金黄色葡萄球菌等抗性细菌，对哺乳动物毒性低，可用作细菌治疗的抗菌剂感染。

25. 发明授权

US5607927A Cephalosporin derivative 失效
标题翻译：头孢菌素衍生物
公开(公告)号：US5607927A
公开(公告)日：1997-03-04
申请号：US385363
申请日：1995-02-07
申请人： Masaki Tsushima , Katsuyoshi Iwamatsu , Atsushi Tamura , Seiji Shibahara
发明人： Masaki Tsushima , Katsuyoshi Iwamatsu , Atsushi Tamura , Seiji Shibahara
IPC分类号： A61K31/545 , A61K31/546 , A61P31/04 , C07D501/00 , C07D501/59 , C07D519/00 , C07D519/06 , C07D501/36
CPC分类号： C07D501/00 , Y02P20/55
摘要： An aminothiazolyl- or aminothiadiazolyl-cephalosporin derivative represented by the following general formula (I) which has a condensed-ring thio group as a 3-positioned substituent group that contains a thiazolylthio group, an oxazolylthio group or a heterocyclic ring thereof as one of the ring components. The compound according to the present invention has excellent activities to inhibit growth of various bacteria, especially Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA), and therefore, the antibacterial agent comprising, as an active ingredient, the inventive compound can be used as a therapeutic drug for the treatment of various bacterial infections. ##STR1##
摘要翻译：作为下述通式（I）表示的氨基噻唑基 - 或氨基噻二唑基 - 头孢菌素衍生物，其具有稠环硫基作为含有噻唑基硫基，恶唑基硫基或其杂环的3位取代基环组件。根据本发明的化合物具有优异的抑制各种细菌，特别是耐甲氧西林金黄色葡萄球菌（MRSA）的革兰氏阳性菌生长的活性，因此作为本发明化合物作为活性成分的抗菌剂可以是用作治疗各种细菌感染的治疗药物。

26. 发明授权

US5194617A 2,3-disubstituted-4-hydroxyquinoline derivatives 失效
标题翻译： 2,3-二取代-4-羟基喹啉衍生物
公开(公告)号：US5194617A
公开(公告)日：1993-03-16
申请号：US807946
申请日：1991-12-10
申请人： Nobuto Minowa , Tomoya Machinami , Takashi Shomura , Masaji Sezaki , Toru Sasaki , Seiji Shibahara , Shigeharu Inouye
发明人： Nobuto Minowa , Tomoya Machinami , Takashi Shomura , Masaji Sezaki , Toru Sasaki , Seiji Shibahara , Shigeharu Inouye
IPC分类号： C07D215/22 , C07D215/233
CPC分类号： C07D215/233
摘要： 2,3-disubstituted-4-hydroxyquinoline derivatives of the general formula (I): ##STR1## [wherein R.sup.1 represents a hydrogen atom or R.sup.3 CO-- (wherein R.sup.3 is a lower alkyl group); R.sup.2 represents a hydrogen atom, --CH.sub.3 or --C.sub.2 H.sub.5 ; A represents ##STR2## and W represents a hydrogen atom, or 1- 4 halogen atoms or alkyl groups which are substituted at the nucleus and may be the same or different] have a strong antagonistic action on leukotriene D.sub.4.
摘要翻译：（I）的2,3-二取代-4-羟基喹啉衍生物：其中R1表示氢原子或R3CO-（其中R3是低级烷基）; R 2表示氢原子，-CH 3或-C 2 H 5; A表示，W表示氢原子或1-4个卤原子或在核上被取代且可相同或不同的烷基对白三烯D4具有强拮抗作用。

27. 发明授权

US5141946A Azole derivatives and anti-ulcerative composition containing same 失效
标题翻译：唑衍生物和含有其的抗溃疡组合物
公开(公告)号：US5141946A
公开(公告)日：1992-08-25
申请号：US716622
申请日：1991-06-14
申请人： Kiyoaki Katano , Tamako Tomomoto , Hiroko Ogino , Naoki Yamazaki , Fumiya Hirano , Yasukatsu Yuda , Fukio Konno , Motohiro Nishio , Tomoya Machinami , Seiji Shibahara , Takashi Tsuruoka , Shigeharu Inouye
发明人： Kiyoaki Katano , Tamako Tomomoto , Hiroko Ogino , Naoki Yamazaki , Fumiya Hirano , Yasukatsu Yuda , Fukio Konno , Motohiro Nishio , Tomoya Machinami , Seiji Shibahara , Takashi Tsuruoka , Shigeharu Inouye
IPC分类号： C07D487/04 , A61K31/435 , A61K31/44 , A61K31/445 , A61K31/495 , A61K31/535 , A61P1/04 , C07D471/04 , C07D498/04 , C07D513/04
CPC分类号： C07D471/04 , C07D513/04
摘要： Compounds of the general formula (I): ##STR1## and pharmaceutically acceptable salts thereof, in whichA, B, C and D each represent --CH.dbd. or --N.dbd., with the proviso that at least one of them is --N.dbd.;X represents --NH--, --O-- or --S--;Y represents --(CH.sub.2).sub.p -- wherein p is an integer from 0 to 4, --C(CH.sub.3).sub.2 --, --CH.sub.2 CH.dbd.CH--, --CH.sub.2 CO--, --CF.sub.2 -- or --CH.sub.2 COCH.sub.2 --;R.sup.1 represents a hydrogen atom, a C.sub.1-4 alkyl group, a halogen atom or a C.sub.1-4 alkoxy group;R.sup.2 represnts a hydrogen atom, a hydroxyl group, a saturated or unsaturated C.sub.1-6 alkyl group, a C.sub.1-6 alkoxy group, a carboxyl group, a saturated or unsaturated C.sub.1-12 alkoxycarbonyl group which may be optionally substituted, a cycloalkoxycarbonyl group, a saturated or unsaturated five- or six-memebered heterocyclic group containing at least one nitrogen atom optionally with one or more nitrogen and/or oxygen atoms, which may be optionally condensed and/or substituted, --CONR.sup.3 R.sup.4, --NR.sup.3 R.sup.4, --OCOR.sup.3 or --NHCONHR.sup.3 wherein R.sup.3 and R.sup.4, which may be the same or different, represent a C.sub.1-6 alkyl group which may be optionally substituted or a cycloalkyl group, andm and n each represent an integrer from 0 to 2.The compounds are useful in treating ulcers.
摘要翻译：通式（I）的化合物：其中A，B，C和D各自表示-CH =或-N =，条件是其中至少一个为 -N =; X表示-NH-，-O-或-S-; Y表示 - （CH 2）p - ，其中p是0至4的整数，-C（CH 3）2 - ， - CH 2 CH = CH - ， - CH 2 CO - ， - CF 2 - 或-CH 2 COCH 2 - R1表示氢原子，C1-4烷基，卤素原子或C1-4烷氧基; R2表示氢原子，羟基，饱和或不饱和的C1-6烷基，C1-6烷氧基，羧基，可以任意取代的饱和或不饱和的C 1-12烷氧基羰基，环烷氧基羰基，含有至少一个氮原子的饱和或不饱和五元或六元杂环基团，任选具有一个或多个氮原子和/或氧原子，其可以任选地被缩合和/或取代，-CONR 3 R 4，-NR 3 R 4，-OCOR 3或 - NHCONHR 3其中R3和R4可以相同或不同，表示可以任选被取代的C 1-6烷基或环烷基，m和n各自表示0至2的整数。该化合物可用于处理溃疡

28. 发明申请

US20120092817A1 DISPLAY DEVICE 审中-公开
标题翻译：显示设备
公开(公告)号：US20120092817A1
公开(公告)日：2012-04-19
申请号：US13253276
申请日：2011-10-05
申请人： Seiji Shibahara , Shizuo Mizukami
发明人： Seiji Shibahara , Shizuo Mizukami
IPC分类号： H05K7/00
CPC分类号： G02F1/13452 , G02F1/1345 , G02F2001/133311 , G02F2001/133331 , G02F2201/50
摘要： A display device including: a display cell that includes a first substrate and a second substrate that are arranged to be opposing, includes a wiring region that is wider than the first substrate on the second substrate, and includes an electrode in the wiring region; a wiring substrate in which at least a portion is arranged to be opposing the wiring region and which is electrically connected to the electrode; a front panel that is provided on a front surface of the first substrate; and a desiccating bonding agent that fixes the front panel to the first substrate while covering from at least a portion of a side surface of the first substrate to a connection portion between the electrode and the wiring substrate.
摘要翻译：一种显示装置，包括：显示单元，包括布置成相对的第一基板和第二基板，包括比所述第二基板上的所述第一基板宽的布线区域，并且在所述布线区域中包括电极; 布线基板，其中至少一部分布置成与布线区域相对并且与电极电连接; 前面板，其设置在所述第一基板的前表面上; 以及干燥粘合剂，其将前面板固定到第一基板，同时从第一基板的侧表面的至少一部分覆盖到电极和布线基板之间的连接部分。

29. 发明授权

US07838089B2 Liquid crystal material, liquid crystal display device and liquid crystal display 有权
标题翻译：液晶材料，液晶显示装置和液晶显示器
公开(公告)号：US07838089B2
公开(公告)日：2010-11-23
申请号：US12336014
申请日：2008-12-16
申请人： Seiji Shibahara
发明人： Seiji Shibahara
IPC分类号： C09K19/52 , C09K19/54 , G02F1/13
CPC分类号： C09K19/3444 , C09K19/12 , C09K19/14 , C09K19/16 , C09K19/2007 , C09K19/22 , C09K19/3003 , C09K19/3028 , C09K19/3098 , C09K19/32 , C09K19/322 , C09K19/3402 , C09K19/3491 , C09K2019/0481 , C09K2019/3027 , C09K2019/3422 , G02F1/0081 , G02F1/13725 , G02F2001/133742 , G02F2001/13712 , Y10T428/10
摘要： A liquid crystal display device capable of obtaining good display characteristics and good response characteristics is provided. A liquid crystal material being a paraelectric material, the liquid crystal material includes: a liquid crystal molecule exhibiting a nematic liquid crystal phase at room temperature and including one or more cyclic structures; and a bent-shaped molecule including cyclic structures which are large in number compared to the cyclic structures included in the liquid crystal molecule.
摘要翻译：提供能够获得良好的显示特性和良好的响应特性的液晶显示装置。作为顺电材料的液晶材料，所述液晶材料包括：在室温下显示向列型液晶相并且包含一个或多个环状结构的液晶分子; 以及包含与包含在液晶分子中的环状结构相比数量多的循环结构的弯曲形分子。

30. 发明申请

US20100039589A1 Dispay Panel and Display Apparatus 有权
标题翻译：分配面板和显示设备
公开(公告)号：US20100039589A1
公开(公告)日：2010-02-18
申请号：US11991791
申请日：2006-06-14
申请人： Seiji Shibahara
发明人： Seiji Shibahara
IPC分类号： G02F1/1335
CPC分类号： G02F1/134309 , G02F1/1337 , G02F1/134363
摘要： Scanning signal lines (41) and data signal lines (47) are arranged so as to cross each other, and common signal lines (42) and the scanning signal lines (41) are arranged to be parallel to each other. Moreover, a polarlizer (37) provided to an upper substrate (36) and a polarlizer (38) provided to a lower substrate (30) are arranged such that absorption axial directions (37a) and (38a) cross at an angle that is orthogonal. Moreover, the absorption axial directions (37a) and (38a) are arranged so as to be perpendicular to or parallel to directions in which the data signal lines (47), the scanning signal lines (41), and the common signal lines (42) are extended, respectively. This realizes an improved response speed and an increased transmissivity.
摘要翻译：扫描信号线（41）和数据信号线（47）被布置为彼此交叉，并且公共信号线（42）和扫描信号线（41）被布置为彼此平行。此外，设置到上基板（36）的极化器（37）和设置在下基板（30）上的极化器（38）被布置成使得吸收轴向（37a）和（38a）以正交的角度交叉。此外，吸收轴方向（37a）和（38a）被布置成垂直于或并联于数据信号线（47），扫描信号线（41）和公共信号线（42）的方向）分别扩展。这实现了改进的响应速度和增加的透射率。

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