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21. 发明授权

US6067996A Nail decoration using ink jets 失效
标题翻译：指甲装饰使用喷墨
公开(公告)号：US6067996A
公开(公告)日：2000-05-30
申请号：US366610
申请日：1999-08-03
申请人： Paul J. Weber , Luiz B. Da Silva , Michael R. Weber
发明人： Paul J. Weber , Luiz B. Da Silva , Michael R. Weber
IPC分类号： A45D34/04 , B41J3/407 , A45D29/00
CPC分类号： B41J3/407 , A45D34/04 , A45D2029/005
摘要： Inkjet printing technology is used to apply a selected design on a fingernail or toenail. The nail printing device applies highly detailed, customized, multicolored designs that are scaled to the size and shape of the individual nail. The device comprises an ink jet print head; a holder for aligning the digit or nail, and a control system that contains the nail designs in an electronic digital form, scales and corrects the designs to the individual nail size and shape, and directs the ink jet print head to apply the scaled design to the nail.
摘要翻译：喷墨打印技术用于将选定的设计应用于指甲或趾甲。指甲打印设备应用高度详细，定制化，多彩多姿的设计，其尺寸与单个钉子的尺寸和形状相符。该装置包括喷墨打印头; 用于对准数字或钉子的保持器以及包含电子数字形式的指甲设计的控制系统，将设计缩放并校正为各个钉子的尺寸和形状，并引导喷墨打印头将缩放的设计应用于指甲。

22. 发明授权

US5931166A Fingernail decorating 失效
标题翻译：指甲装饰
公开(公告)号：US5931166A
公开(公告)日：1999-08-03
申请号：US218579
申请日：1998-12-22
申请人： Paul J. Weber , Michael R. Weber , Luiz B. Da Silva
发明人： Paul J. Weber , Michael R. Weber , Luiz B. Da Silva
IPC分类号： A45D34/04 , B41J3/407 , A45D29/00
CPC分类号： B41J3/407 , A45D34/04 , A45D2029/005
摘要： The invention provides a method and an apparatus for decorating or coloring fingernails or toenails. According to the method, a subject's fingernail is scanned to obtain an image and the image is transferred to a computer. The computer then maps out the fingernail surface and scales a selected image or design to fit on the fingernail. This information is then used by the computer to activate an inkjet assembly to print out the stored image on the fingernail surface.
摘要翻译：本发明提供了一种用于装饰或着色指甲或脚趾甲的方法和装置。根据该方法，扫描对象的指甲以获得图像，并将图像传送到计算机。计算机然后映射出指甲表面并缩放选定的图像或设计以适应指甲。该信息随后被计算机使用以激活喷墨组件以将存储的图像打印在指甲表面上。

23. 发明授权

US07494492B2 Skin treatment device 有权
标题翻译：皮肤治疗装置
公开(公告)号：US07494492B2
公开(公告)日：2009-02-24
申请号：US11216595
申请日：2005-08-30
申请人： Luiz B. Da Silva , George Choi
发明人： Luiz B. Da Silva , George Choi
IPC分类号： A61B18/08
CPC分类号： A61B18/082 , A61B2017/00734 , A61B2017/00761
摘要： A compact hand held device is provided that can be safely used by those suffering from acne, blemished skin or fine wrinkles. The hand held device includes an on/off switch and a button that pulses the device when it is placed on the target site. A battery within the device powers a circuit board and drives a short pulse of current through a heating element, which heats up to approximately 300° C. in less than 0.1 sec. Thermal conduction transfers the heat to the skin and causes a biological response that accelerates acne clearing, treats blemished skin or fine wrinkles. The total heat transferred is low enough to prevent burns. Application of acne treatment creams and gels further accelerates treatment
摘要翻译：提供了一个紧凑的手持装置，可以被那些患有痤疮，瑕疵的皮肤或细皱纹的人安全使用。手持设备包括一个开/关开关和一个按钮，当设备放置在目标站点上时，该按钮将脉冲。设备内的电池为电路板供电，并通过加热元件驱动短脉冲电流，加热元件在小于0.1秒内加热至约300°C。热传导将热量转移到皮肤，并引起加速痤疮清除，治疗瑕疵皮肤或细皱纹的生物反应。传热的总热量足够低以防止灼伤。痤疮治疗霜和凝胶的应用进一步加速治疗

24. 发明授权

US06607500B2 Integrated cast and muscle stimulation system 失效
公开(公告)号：US06607500B2
公开(公告)日：2003-08-19
申请号：US09853440
申请日：2001-05-10
申请人： Luiz B. Da Silva , Michael R. Weber , David I. Blatt , Jeffrey S. Mannheimer
发明人： Luiz B. Da Silva , Michael R. Weber , David I. Blatt , Jeffrey S. Mannheimer
IPC分类号： A61F501
CPC分类号： A61N1/36003 , A61N1/0452 , A61N1/0456 , A61N1/0464 , A61N1/0472 , A61N1/32 , A61N1/326 , A61N1/36021
摘要： The present invention is a device that allows electrical stimulation to an anatomical site that is covered by a cast. The electrode is applied to achieve a desired physiological response (e.g., bone growth), treatment of pain, or the prevention of muscle atrophy.

25. 发明授权

US06538739B1 Bubble diagnostics 失效
标题翻译：气泡诊断
公开(公告)号：US06538739B1
公开(公告)日：2003-03-25
申请号：US08941015
申请日：1997-09-30
申请人： Steven R. Visuri , Beth M. Mammini , Luiz B. Da Silva , Peter M. Celliers
发明人： Steven R. Visuri , Beth M. Mammini , Luiz B. Da Silva , Peter M. Celliers
IPC分类号： G01B1100
CPC分类号： G01N21/431 , A61B18/20 , A61B18/26 , A61B2017/00057 , A61B2017/22008 , A61B2018/00636
摘要： The present invention is intended as a means of diagnosing the presence of a gas bubble and incorporating the information into a feedback system for opto-acoustic thrombolysis. In opto-acoustic thrombolysis, pulsed laser radiation at ultrasonic frequencies is delivered intraluminally down an optical fiber and directed toward a thrombus or otherwise occluded vessel. Dissolution of the occlusion is therefore mediated through ultrasonic action of propagating pressure or shock waves. A vapor bubble in the fluid surrounding the occlusion may form as a result of laser irradiation. This vapor bubble may be used to directly disrupt the occlusion or as a means of producing a pressure wave. It is desirable to detect the formation and follow the lifetime of the vapor bubble. Knowledge of the bubble formation and lifetime yields critical information as to the maximum size of the bubble, density of the absorbed radiation, and properties of the absorbing material. This information can then be used in a feedback system to alter the irradiation conditions.
摘要翻译：本发明旨在作为诊断气泡的存在并将该信息并入用于光声溶解的反馈系统中的手段。在光声波溶解中，超声频率下的脉冲激光辐射在光纤内向内递送并引向血栓或其它闭塞血管。因此，阻塞的溶解通过传播压力或冲击波的超声波作用来介导。作为激光照射的结果，可以形成围绕闭塞的流体中的蒸气泡。该气泡可用于直接破坏闭塞或产生压力波的手段。需要检测形成并遵循蒸气泡的寿命。关于气泡形成和寿命的知识产生关于气泡的最大尺寸，吸收辐射的密度和吸收材料的性质的关键信息。然后可以在反馈系统中使用该信息来改变照射条件。

26. 发明授权

US06522407B2 Optical detection dental disease using polarized light 有权
标题翻译：光学检测牙病使用偏振光
公开(公告)号：US06522407B2
公开(公告)日：2003-02-18
申请号：US10100824
申请日：2002-03-18
申请人： Matthew J. Everett , Billy W. Colston, Jr. , Ujwal S. Sathyam , Luiz B. Da Silva , Daniel Fried
发明人： Matthew J. Everett , Billy W. Colston, Jr. , Ujwal S. Sathyam , Luiz B. Da Silva , Daniel Fried
IPC分类号： G01J400
CPC分类号： A61B5/0088 , A61B5/0066 , A61B5/0073 , G01B9/02091 , G01B2290/70 , G01N21/4795
摘要： A polarization sensitive optical imaging system is used to detect changes in polarization in dental tissues to aid the diagnosis of dental disease such as caries. The degree of depolarization is measured by illuminating the dental tissue with polarized light and measuring the polarization state of the backscattered light. The polarization state of this reflected light is analyzed using optical polarimetric imaging techniques. A hand-held fiber optic dental probe is used in vivo to direct the incident beam to the dental tissue and collect the reflected light. To provide depth-resolved characterization of the dental tissue, the polarization diagnostics may be incorporated into optical coherence domain reflectometry and optical coherence tomography (OCDR/OCT) systems, which enables identification of subsurface depolarization sites associated with demineralization of enamel or bone.
摘要翻译：偏振敏感光学成像系统用于检测牙组织中极化的变化，以帮助牙科疾病如龋齿的诊断。通过用偏振光照射牙组织并测量背向散射光的偏振状态来测量去极化度。使用光学偏振成像技术分析该反射光的偏振状态。体内使用手持光纤牙科探针将入射光束引导到牙齿组织并收集反射光。为了提供牙科组织的深度分辨表征，偏振诊断可以被并入到光学相干畴反射测量和光学相干断层扫描（OCDR / OCT）系统中，其能够识别与釉质或骨的脱矿质相关的地下去极化位点。

27. 发明授权

US07749260B2 Devices and methods for treatment of skin conditions 有权
标题翻译：用于治疗皮肤病症的装置和方法
公开(公告)号：US07749260B2
公开(公告)日：2010-07-06
申请号：US11299284
申请日：2005-12-09
申请人： Luiz B. Da Silva , George Choi , Joseph Neev
发明人： Luiz B. Da Silva , George Choi , Joseph Neev
IPC分类号： A61F7/00
CPC分类号： A61B18/082 , A61B2017/00734 , A61B2017/00761 , A61B2018/00005 , A61B2018/0047 , A61B2018/00714 , A61B2018/00761 , A61B2018/00791
摘要： Devices and methods for the treatment of skin conditions and lesions are disclosed herein. One aspect of the invention is a compact hand held device that can be safely used by those suffering from skin conditions, such as acne, warts, cold blisters, blemished skin, or fine wrinkles. The devices described herein employ the application of heat for the treatment of skin conditions and lesions. Typically, the peak temperatures employed are about 70° C. to about 400° C. by the devices, are achieved in less than about 1 second, and maintained for less than about 1 second. In some embodiments, the skin surface is heated with heat pulses. Thermal conduction transfers heat from the device to the skin and causes a biological response that accelerates acne clearing, treats blemished skin, itching, or fine wrinkles. The total heat transferred is low enough to prevent burns.
摘要翻译：本文公开了用于治疗皮肤病况和损伤的装置和方法。本发明的一个方面是紧凑的手持装置，其可以被患有皮肤状况的人安全地使用，例如痤疮，疣，冷水泡，瑕疵的皮肤或细皱纹。本文描述的装置使用热量来治疗皮肤病症和损伤。通常，所用装置的峰值温度为约70℃至约400℃，在小于约1秒钟内实现，并保持少于约1秒。在一些实施方案中，用热脉冲加热皮肤表面。热传导将热量从设备传递到皮肤，并引起加速痤疮清除，治疗瑕疵皮肤，瘙痒或细皱纹的生物反应。传热的总热量足够低以防止灼伤。

28. 发明申请

US20080139974A1 Devices and Methods for Treatment of Skin Conditions 有权
标题翻译：用于治疗皮肤病症的装置和方法
公开(公告)号：US20080139974A1
公开(公告)日：2008-06-12
申请号：US11947607
申请日：2007-11-29
申请人： Luiz B. Da Silva
发明人： Luiz B. Da Silva
IPC分类号： A61N7/00 , A61B18/04 , A61H1/00
CPC分类号： A61N7/00 , A61B8/546 , A61B2017/00734 , A61B2018/00005 , A61N2007/0056
摘要： Devices and methods for the treatment of skin conditions and lesions are disclosed herein. A compact hand held device that can be safely used by those suffering from skin conditions, such as acne, warts, cold blisters, blemished skin, or fine wrinkles. The devices employ the application of ultrasound energy and heat for the treatment of skin conditions and lesions. Typically, the peak temperatures employed are about 40° C. to about 70° C. by the devices, are achieved in less than about 20 second, and maintained for less than about 40 second. Ultrasound absorption and thermal conduction transfers heat from the device to the skin and causes a biological response that accelerates acne clearing, treats blemished skin, itching, or fine wrinkles. The total heat transferred is low enough to prevent burns.
摘要翻译：本文公开了用于治疗皮肤病况和损伤的装置和方法。一种紧凑的手持式装置，可以被那些患有皮肤病症的人安全使用，如痤疮，疣，冷水泡，瑕疵的皮肤或细纹。这些装置采用超声能量和热量来治疗皮肤病症和病变。通常，所用装置的峰值温度为约40℃至约70℃，在小于约20秒内达到，并保持少于约40秒。超声吸收和热传导将热量从装置转移到皮肤，并引起加速痤疮清除，治疗瑕疵皮肤，瘙痒或细皱纹的生物反应。传热的总热量足够低以防止灼伤。

29. 发明授权

US06647285B2 Optical probe with light fluctuation protection 失效
标题翻译：光探头具有光波动保护
公开(公告)号：US06647285B2
公开(公告)日：2003-11-11
申请号：US09997470
申请日：2001-11-29
申请人： Luiz B. Da Silva , Charles L. Chase
发明人： Luiz B. Da Silva , Charles L. Chase
IPC分类号： A61B600
CPC分类号： A61B5/0084 , A61B5/0091 , A61B5/4312
摘要： An optical probe for tissue identification includes an elongated body. Optical fibers are located within the elongated body for transmitting light to and from the tissue. Light fluctuation protection is associated with the optical fibers. In one embodiment the light fluctuation protection includes a reflective coating on the optical fibers to reduce stray light. In another embodiment the light fluctuation protection includes a filler with very high absorption located within the elongated body between the optical fibers.
摘要翻译：用于组织识别的光学探针包括细长体。光纤位于细长体内，用于将光传送到组织和从组织发射光。光波动保护与光纤相关联。在一个实施例中，光波动保护包括在光纤上的反射涂层以减少杂散光。在另一个实施例中，光波动保护包括位于光纤之间的细长主体内的具有非常高吸收的填充物。

30. 发明授权

US06491685B2 Laser and acoustic lens for lithotripsy 失效
标题翻译：激光和声透镜用于碎石术
公开(公告)号：US06491685B2
公开(公告)日：2002-12-10
申请号：US09516999
申请日：2000-03-01
申请人： Steven R. Visuri , Anthony J. Makarewicz , Richard A. London , William J. Benett , Peter Krulevitch , Luiz B. Da Silva
发明人： Steven R. Visuri , Anthony J. Makarewicz , Richard A. London , William J. Benett , Peter Krulevitch , Luiz B. Da Silva
IPC分类号： A61B1722
CPC分类号： A61B18/26 , A61B2018/263
摘要： An acoustic focusing device whose acoustic waves are generated by laser radiation through an optical fiber. The acoustic energy is capable of efficient destruction of renal and biliary calculi and deliverable to the site of the calculi via an endoscopic procedure. The device includes a transducer tip attached to the distal end of an optical fiber through which laser energy is directed. The transducer tip encapsulates an exogenous absorbing dye. Under proper irradiation conditions (high absorbed energy density, short pulse duration) a stress wave is produced via thermoelastic expansion of the absorber for the destruction of the calculi. The transducer tip can be configured into an acoustic lens such that the transmitted acoustic wave is shaped or focused. Also, compressive stress waves can be reflected off a high density/low density interface to invert the compressive wave into a tensile stress wave, and tensile stresses may be more effective in some instances in disrupting material as most materials are weaker in tension than compression. Estimations indicate that stress amplitudes provided by this device can be magnified more than 100 times, greatly improving the efficiency of optical energy for targeted material destruction.
摘要翻译：声波聚焦装置，其声波通过激光辐射通过光纤产生。声能能够有效地破坏肾脏和胆汁结石，并可通过内窥镜手术递送至结石部位。该装置包括附接到光纤的远端的换能器尖端，通过激光能量被引导。换能器尖端封装外源吸收染料。在适当的照射条件（高吸收能量密度，短脉冲持续时间）下，通过吸收器的热弹性膨胀产生应力波，以破坏结石。换能器尖端可以被配置成声透镜，使得发射的声波成形或聚焦。此外，压应力波可以从高密度/低密度界面反射，以将压缩波反转成拉伸应力波，并且拉伸应力在某些情况下在破坏材料中可能更有效，因为大多数材料的张力比压缩弱。估计表明，该装置提供的应力幅度可以放大100倍以上，大大提高了光能量对目标材料的破坏效率。

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