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    • 24. 发明授权
    • 5-Alkoxy-picolinic acid calcium salts and anti-hypertensive composition
containing 5-alkoxy-picolinic acid calcium salts and anti-hypertensive
composition thereof
    • 含有5-烷氧基 - 吡啶甲酸钙盐及其抗高血压组合物的5-烷氧基 - 吡啶甲酸钙盐和抗高血压组合物
    • US4189489A
    • 1980-02-19
    • US838180
    • 1977-09-30
    • Takemi KoedaTakashi TsuruokaUichi ShibataHiroyasu AsaokaMitsugu HachisuOsamu ItohYasuharu SekizawaShigeharu InouyeTaro Niida
    • Takemi KoedaTakashi TsuruokaUichi ShibataHiroyasu AsaokaMitsugu HachisuOsamu ItohYasuharu SekizawaShigeharu InouyeTaro Niida
    • A61K31/44A61P9/12C07D213/65C07D213/79A61K31/445C07D213/89
    • C07D213/79C07D213/65
    • 5-Alkoxy-picolinic acids and the salts and the esters thereof represented by the formula (I): ##STR1## wherein R represents an alkyl group having 1 to 6 carbon atoms and M represents a hydrogen atom; a calcium atom; a sodium atom; a potassium atom; an aluminum atom; an unsubstituted phenyl group; a phenyl group substituted with one or more of an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms or a halogen atom (such as a chlorine, bromine, iodine, etc., atom); a phthalidyl group; an alkoxyalkyl group wherein the alkyl moiety and the alkoxy moiety each has 1 to 4 carbon atoms; or an acyloxyalkyl group having the formula ##STR2## wherein R.sub.2 represents a hydrogen atom or a methyl group and R.sub.3 represents an alkyl group having 1 to 5 carbon atoms (such as a methyl, n-propyl, isobutyl, t-butyl, etc., group), an alkoxy group having 1 to 4 carbon atoms, a phenyl group, a phenyl group substituted with one or more of an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms or a halogen atom (such as a chlorine, bromine, iodine, etc., atom) or an aralkyl group wherein the alkyl moiety has 1 to 3 carbon atoms, which are useful as anti-hypertensive agents, a process for preparing 5-alkoxy-picolinic acids and the salts and the esters thereof, and anti-hypertensive compositions containing the 5-alkoxy-picolinic acids and the salts and the esters thereof.
    • 5-烷氧基 - 吡啶甲酸及其由式(I)表示的盐及其酯:其中R表示具有1至6个碳原子的烷基,M表示氢原子; 钙原子; 一个钠原子; 钾原子; 铝原子; 未取代的苯基; 被一个或多个具有1至4个碳原子的烷基,具有1至4个碳原子的烷氧基或卤素原子(例如氯,溴,碘等)原子取代的苯基; 苯酞基; 其中烷基部分和烷氧基部分各自具有1至4个碳原子的烷氧基烷基; 或具有式“IMAGE”的酰氧基烷基,其中R 2表示氢原子或甲基,R 3表示具有1至5个碳原子的烷基(例如甲基,正丙基,异丁基,叔丁基等) ,基团),具有1至4个碳原子的烷氧基,苯基,被一个或多个具有1至4个碳原子的烷基取代的苯基,具有1至4个碳原子的烷氧基或卤素原子 (例如氯,溴,碘等原子)或其中烷基部分具有1至3个碳原子的芳烷基,其可用作抗高血压剂,制备5-烷氧基 - 吡啶甲酸的方法和 其盐和酯,以及含有5-烷氧基 - 吡啶甲酸及其盐及其酯的抗高血压组合物。
    • 25. 发明授权
    • Translucent reflective type liquid crystal display
    • 半透明反光型液晶显示屏
    • US07277143B2
    • 2007-10-02
    • US10522772
    • 2002-09-20
    • Katsuyuki FunahataMakoto AbeOsamu ItohShinichi Komura
    • Katsuyuki FunahataMakoto AbeOsamu ItohShinichi Komura
    • G02F1/1335
    • G02F1/133555G02F1/136227
    • A low cost transflective type liquid crystal display is provided which can display a bright image with high contrast under both indoor and outdoor illumination environments. The liquid crystal display performing transmission type display and reflection type display, includes: a plurality of pixels surrounded on a substrate 10 by a plurality of gate electrodes 11 and a plurality of source electrodes 15 arranged perpendicularly to the gate electrodes; a switching element 19 arranged in each pixel and disposed neat at the intersection between each gate electrode and each source electrode; and a pixel electrode 16 connected to the switching element, wherein the pixel electrode is constituted of a transparent conductive layer and a conductive member 17 having a light reflection function and electrically connected to the transparent conductive layer.
    • 提供了一种低成本半透式液晶显示器,其可以在室内和室外照明环境下显示具有高对比度的明亮图像。 执行透射型显示和反射型显示的液晶显示器包括:通过多个栅电极11和与栅电极垂直设置的多个源极15围绕在基板10上的多个像素; 开关元件19布置在每个像素中并且整齐地布置在每个栅电极和每个源极之间的交叉处; 以及连接到开关元件的像素电极16,其中像素电极由透明导电层和具有光反射功能的导电构件17构成,并且电连接到透明导电层。
    • 26. 发明授权
    • Method for preparing [F-18-]fluoride ion
    • [F-18-]氟离子的制备方法
    • US06190637B1
    • 2001-02-20
    • US09266603
    • 1999-03-11
    • Sento InoMasahiko TamuraOsamu Itoh
    • Sento InoMasahiko TamuraOsamu Itoh
    • A61K5100
    • G21G1/10C07B59/00G21G2001/0015
    • The present invention provides a method for preparing [F-18]-fluoride ion which comprises the step of bringing [O-18]-enriched water containing [F-18]-fluoride ion formed by proton irradiation of [O-18]-enriched water into contact with a strongly acidic cation exchange resin to remove impurity cations, the step of then bringing the [O-18]-enriched water containing [F-18]-fluoride ion treated above into contact with a weakly basic anion exchange resin to make [F-18]-fluoride ion adsorbed to the resin and, along therewith, to recover the [O-18]-enriched water which has passed through the resin, and the step of eluting and collecting the [F-18]-fluoride ion adsorbed to the weakly basic anion exchange resin. According to the method for preparing [F-18]-fluoride ion of the present invention, [F-18]-fluoride ion can be collected at a high collection efficiency even from a larger amount (about 2 ml or more) of [O-18]-enriched water containing [F-18]-fluoride ion than the amount in prior method, and moreover expensive [O-18]-enriched water can be recovered and reused in the preparation of [F-18]-fluoride ion.
    • 本发明提供了制备[F-18] - 氟化物离子的方法,该方法包括使含有[O-18] - 氟化物离子的[O-18] - 含氟[ 富含水与强酸性阳离子交换树脂接触以除去杂质阳离子,然后将含有上述[F-18] - 氟化物离子的[O-18]富含水的水溶液与弱碱性阴离子交换树脂接触的步骤 使[F-18] - 氟化物离子吸附到树脂上,并与其一起回收已经通过树脂的[O-18]富含水,以及洗脱和收集[F-18] 氟离子吸附到弱碱性阴离子交换树脂上。 根据本发明的[F-18] - 氟化物离子的制备方法,即使从大量(约2ml以上)的[O -18]富含[F-18] - 氟离子的富含水的水,而且[F-18] - 氟化物离子的制备中可以回收并重复使用富含[O-18]的富含水的[F-18] 。
    • 28. 发明授权
    • 5-Alkoxy-picolinic esters and anti-hypertensive composition containing
5-alkoxy-picolinic esters
    • 5-烷氧基 - 吡啶甲酸酯和含有5-烷氧基 - 吡啶甲酸酯的抗高血压组合物
    • US4198416A
    • 1980-04-15
    • US944683
    • 1978-09-22
    • Takemi KoedaTakashi TsuruokaUichi ShibataHiroyasu AsaokaMitsugu HachisuOsamu ItohYasuharu SekizawaShigeharu InouyeTaro Niida
    • Takemi KoedaTakashi TsuruokaUichi ShibataHiroyasu AsaokaMitsugu HachisuOsamu ItohYasuharu SekizawaShigeharu InouyeTaro Niida
    • C07D213/65C07D213/79A61K31/44
    • C07D213/79C07D213/65
    • 5-Alkoxy-picolinic esters represented by the formula (I): ##STR1## wherein R represents an alkyl group having 1 to 6 carbon atoms and R.sub.1 represents an unsubstituted phenyl group; a phenyl group substituted with one or more of an alkyl group having 1 to 4 carbon atoms or an acetyl group; a phthalidyl group; an alkoxyalkyl group wherein the alkyl moiety and the alkoxy moiety each has 1 to 4 carbon atoms; an alkoxyalkoxyalkyl group wherein the alkyl moiety and the alkoxy moiety each has 1 to 4 carbon atoms; an indanyl group; or an acyloxyalkyl group having the formula ##STR2## wherein R.sub.2 represents a hydrogen atom or a methyl group and R.sub.3 represents an alkyl group having 1 to 5 carbon atoms (such as a methyl, n-propyl, isobutyl, t-butyl, etc., group), an alkoxy group having 1 to 4 carbon atoms, a phenyl group, a phenyl group substituted with one or more of an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms or a halogen atom (such as chlorine, bromine, iodine, etc., atom) or an aralkyl group wherein the alkyl moiety has 1 to 3 carbon atoms, which are useful as anti-hypertensive agents, a process for preparing 5-alkoxy-picolinic esters, and anti-hypertensive compositions containing the 5-alkoxy-picolinic esters.
    • 由式(I)表示的5-烷氧基 - 吡啶甲酸酯:其中R表示具有1至6个碳原子的烷基,R 1表示未取代的苯基; 被一个或多个具有1至4个碳原子的烷基或乙酰基取代的苯基; 苯酞基; 其中烷基部分和烷氧基部分各自具有1至4个碳原子的烷氧基烷基; 其中烷基部分和烷氧基部分各自具有1至4个碳原子的烷氧基烷氧基烷基; 茚满基; 或具有式“IMAGE”的酰氧基烷基,其中R 2表示氢原子或甲基,R 3表示具有1至5个碳原子的烷基(例如甲基,正丙基,异丁基,叔丁基等) ,基团),具有1至4个碳原子的烷氧基,苯基,被一个或多个具有1至4个碳原子的烷基取代的苯基,具有1至4个碳原子的烷氧基或卤素原子 (例如氯,溴,碘等原子)或其中烷基部分具有1〜3个碳原子的芳烷基,其可用作抗高血压剂,制备5-烷氧基 - 吡啶甲酸酯的方法和 含有5-烷氧基 - 吡啶甲酸酯的抗高血压组合物。
    • 29. 发明申请
    • METHOD FOR PRODUCING REGENERATED TARGET
    • 生产再生目标的方法
    • US20110256013A1
    • 2011-10-20
    • US13141261
    • 2009-12-17
    • Toshiya YamamotoTakanobu MiyashitaOsamu Itoh
    • Toshiya YamamotoTakanobu MiyashitaOsamu Itoh
    • B22F3/14B22F7/00
    • B22F7/02C04B35/645C23C14/3414
    • A sintering method with uniaxial pressing includes: a powder filling step of disposing a spent target in an inner space of a frame jig having the inner space piercing in a uniaxial direction, and filling the inner space with a raw material powder for a target to cover an erosion part side of the spent target with the raw material powder for a target, a cushioning-material disposition step of disposing a deformable cushioning material so that the raw material powder for a target with which the inner space has been filled in the powder filling step is sandwiched between the spent target and the deformable cushioning material; and a sintering step of pressing the raw material powder for a target with which the inner space has been filled and the spent target in the uniaxial direction through the cushioning material and sintering them.
    • 具有单轴压制的烧结方法包括:粉末填充步骤,将废靶设置在具有沿着单轴方向穿透的内部空间的框架夹具的内部空间中,并且将内部空间填充到用于覆盖目标的原料粉末 用于目标物的原料粉末的废弃物的侵蚀部分侧,缓冲材料配置步骤,设置可变形的缓冲材料,使得已经填充有内部空间的靶材的原料粉末填充到粉末填充物中 步骤夹在废料和可变形缓冲材料之间; 以及烧结步骤,通过缓冲材料将填充有内部空间的靶材的原料粉末和沿单轴方向的废弃物料按压,并烧结。
    • 30. 发明授权
    • Pressure sensor
    • 压力传感器
    • US07404330B2
    • 2008-07-29
    • US11717167
    • 2007-03-13
    • Hiroshi UchigashimaKiyoshi OtsukaOsamu Itoh
    • Hiroshi UchigashimaKiyoshi OtsukaOsamu Itoh
    • G01L9/00
    • G01L9/0042G01L19/0084G01L19/143
    • A pressure sensor includes a metal housing and a semiconductor chip. The housing has a diaphragm unitary with the housing and an inlet for introducing fluid to the diaphragm. The inlet has a first end exposed to the diaphragm and a second end exposed to an outside of the housing. The housing has a thin-wall portion at the first end of the inlet and the thin-wall portion serves as the diaphragm. The chip is mounted on the diaphragm. The area and thickness of the chip are set so that separation between the chip and diaphragm can be prevented. Since the separation is prevented based on the area and thickness of the chip, there is no need that the diaphragm is made of a material having a thermal expansion coefficient similar to that of the chip.
    • 压力传感器包括金属壳体和半导体芯片。 壳体具有与壳体一体的隔膜和用于将流体引入隔膜的入口。 入口具有暴露于隔膜的第一端和暴露于壳体外部的第二端。 壳体在入口的第一端具有薄壁部分,薄壁部分用作隔膜。 芯片安装在隔膜上。 芯片的面积和厚度被设定为能够防止芯片和隔膜之间的间隔。 由于基于芯片的面积和厚度来防止分离,因此不需要由具有与芯片的热膨胀系数相似的热膨胀系数的材料制成隔膜。