专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明授权

US08211697B2 Induced pluripotent stem cells produced using reprogramming factors and a rho kinase inhibitor or a histone deacetylase inhibitor 有权
标题翻译：使用重编程因子和rho激酶抑制剂或组蛋白脱乙酰酶抑制剂产生的诱导多能干细胞
公开(公告)号：US08211697B2
公开(公告)日：2012-07-03
申请号：US12157967
申请日：2008-06-13
申请人： Kazuhiro Sakurada , Hideki Masaki , Tetsuya Ishikawa , Shunichi Takahashi
发明人： Kazuhiro Sakurada , Hideki Masaki , Tetsuya Ishikawa , Shunichi Takahashi
IPC分类号： C12N5/02 , C12N15/00
CPC分类号： C12N15/85 , C12N5/0696 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/606 , C12N2510/00 , C12N2799/027
摘要： Described herein are multipotent stem cells, e.g., human and other mammalian pluripotent stem cells, and related methods.
摘要翻译：本文描述的是多能干细胞，例如人和其他哺乳动物多能干细胞，以及相关方法。

22. 发明申请

US20110039332A1 HUMAN PLURIPOTENT STEM CELLS INDUCED FROM UNDIFFERENTIATED STEM CELLS DERIVED FROM A HUMAN POSTNATAL TISSUE 审中-公开
标题翻译：从人类后组织衍生的不同的干细胞诱导的人PLUIPOTENT干细胞
公开(公告)号：US20110039332A1
公开(公告)日：2011-02-17
申请号：US12663840
申请日：2007-11-20
申请人： Kazuhiro Sakurada , Hldeki Masaki , Tetsuya Ishikawa , Shunichi Takahashi
发明人： Kazuhiro Sakurada , Hldeki Masaki , Tetsuya Ishikawa , Shunichi Takahashi
IPC分类号： C12N5/071 , C12N5/0735
CPC分类号： C12N15/85 , C12N5/0696 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/606 , C12N2510/00 , C12N2799/027
摘要： To establish human pluripotent stem cells having properties close to human ES cells comprising the genome of the patient per se that can circumvent immunological rejection of transplanted cells from cells derived from a postnatal human tissue. It was found that human pluripotent stem cells can be induced by introducing three genes of Oct3/4, Sox2 and KIf 4, or three genes of Oct3/4, Sox2 and KIf 4 plus the c-Myc gene or a histone deacetylase (HDAC) inhibitor to undifferentiated stem cells present in various human postnatal tissues in which each gene of Tert, Nanog, Oct3/4 and Sox2 has not undergone epigenetic inactivation.
摘要翻译：建立具有接近人类ES细胞的人类多能干细胞，其包含患者本身的基因组，其可以规避来自出生后人体组织的细胞的移植细胞的免疫排斥。发现人类多能干细胞可以通过引入Oct3 / 4，Sox2和KIf4的三个基因或Oct3 / 4，Sox2和KIf4的三个基因加上c-Myc基因或组蛋白脱乙酰酶（HDAC）来诱导，抑制剂存在于各种人类出生后组织中的未分化干细胞，其中Tert，Nanog，Oct3 / 4和Sox2的每个基因未经历表观遗传学失活。

23. 发明授权

US07748671B2 Suction cup device 失效
标题翻译：吸杯装置
公开(公告)号：US07748671B2
公开(公告)日：2010-07-06
申请号：US11841293
申请日：2007-08-20
申请人： Shunichi Takahashi
发明人： Shunichi Takahashi
IPC分类号： A45D42/14
CPC分类号： F16B47/00
摘要： Herein disclosed a suction cup device including: a case; a suction cup of which a surface on one side in the thickness direction thereof is a suction surface and a surface on the other side is a back surface; a displacement mechanism provided in the case and operative to support a central part in the radial direction of the back surface of the suction cup in such a manner that the central part can be displaced in the thickness direction; and a contact part which is provided in the case and which, when the suction surface makes suction contact with a surface to be sucked, can make contact with a part, on the outside of the suction contact part of the surface to be sucked, of the surface to be sucked, wherein the contact part includes a plurality of contact elements spaced from each other and making contact with a plurality of parts of said surface to be sucked which are spaced at intervals in the circumferential direction of the suction cup.
摘要翻译：这里公开了一种吸盘装置，包括：壳体; 其厚度方向一侧的表面是吸附面，另一侧的表面为背面的吸盘，所述位移机构设置在所述壳体中并且可操作以使得所述中心部分能够在所述厚度方向上移位的方式支撑所述吸盘的所述后表面的径向方向上的中心部分; 以及接触部，其设置在壳体中，并且当吸引面与要吸附的表面进行吸力接触时，可以与待吸附的表面的吸力接触部分的外侧的部分接触待吸附的表面，其中所述接触部分包括彼此间隔开的多个接触元件，并且与所述吸盘周向隔开间隔开的所述待吸附表面的多个部分接触。

24. 发明申请

US20090304646A1 Multipotent/Pluripotent Cells and Methods 审中-公开
标题翻译：多能/多能细胞和方法
公开(公告)号：US20090304646A1
公开(公告)日：2009-12-10
申请号：US12465633
申请日：2009-05-13
申请人： Kazuhiro Sakurada , Hideki Masaki , Tetsuya Ishikawa , Shunichi Takahashi
发明人： Kazuhiro Sakurada , Hideki Masaki , Tetsuya Ishikawa , Shunichi Takahashi
IPC分类号： A61K35/12 , C12N5/08 , C12Q1/68
CPC分类号： C12N15/85 , C12N5/0696 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/606 , C12N2510/00 , C12N2799/027
摘要： Described herein are multipotent stem cells, e.g., human and other mammalian pluripotent stem cells, and related methods.
摘要翻译：本文描述的是多能干细胞，例如人和其他哺乳动物多能干细胞，以及相关方法。

25. 发明授权

US06352061B2 Control device for a variable valve timing mechanism of an engine 失效
标题翻译：发动机可变气门正时机构的控制装置
公开(公告)号：US06352061B2
公开(公告)日：2002-03-05
申请号：US09772827
申请日：2001-01-30
申请人： Shunichi Takahashi
发明人： Shunichi Takahashi
IPC分类号： F01L134
CPC分类号： F01L1/34 , F01L1/3442 , F01L2001/34426 , F01L2001/3444 , F01L2001/34469 , F01L2800/00 , F01L2820/041 , Y10T477/675
摘要： An engine control device with a variable valve timing mechanism is provided for preventing an abrupt engine output fluctuation in the process of transmission operation or lock up clutch switching operation in an engine with the variable valve timing mechanism, and a torque shock is restrained accordingly. An ECU determines whether or not an automatic transmission is in the process of transmission operation or whether or not a lock up clutch is in the process of switching. If the automatic transmission is in the process of transmission operation or the lock up clutch is in the process of switching, a target valve timing is not updated, and the valve timing at the time is held. Thus, the operation of a VVT in the process of transmission operation of the automatic transmission or the switching operation of the lock up clutch is stopped, so that an engine output fluctuation caused by change in the valve timing can be prevented and the torque shock can be restrained.
摘要翻译：提供一种具有可变气门正时机构的发动机控制装置，用于防止变速器操作过程中的发动机输出突然变化或使用可变气门正时机构锁定发动机中的离合器切换操作，并且相应地抑制转矩冲击。 ECU判断自动变速器是否处于变速器运转过程中，或者锁止离合器是否处于切换过程中。如果自动变速器处于变速器运转或锁止离合器处于切换过程中，则不能更新目标气门正时，并且保持此时的气门正时。因此，在自动变速器的变速器运转或锁止离合器的切换动作的过程中，VVT的动作停止，从而可以防止由气门正时变化引起的发动机输出变动，被束缚

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式