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21. 发明申请

US20060195153A1 System and method for selectively stimulating different body parts 有权
标题翻译：选择性刺激不同身体部位的系统和方法
公开(公告)号：US20060195153A1
公开(公告)日：2006-08-31
申请号：US11343627
申请日：2006-01-31
申请人： Anthony DiUbaldi , Michael Tracey
发明人： Anthony DiUbaldi , Michael Tracey
IPC分类号： A61N1/18
CPC分类号： A61N1/0492 , A61N1/0551 , A61N1/36003 , A61N1/36007 , A61N1/36014 , A61N1/36017 , A61N1/36021
摘要： A device and method is provided for transdermally stimulating selected body parts of a mammal. The device includes a first waveform generator adapted to generate a first waveform having a first frequency capable of stimulating a first predetermined body part, a second waveform generator adapted to generate a carrier waveform having a second frequency capable of passing through tissue of the mammal, and a third waveform generator adapted to generate a third waveform having a third frequency different from and out of phase with that of the first waveform, and capable of stimulating a second predetermined body part. The device further includes a modulation device electrically coupled to the first, second and third waveform generators and adapted to modulate the carrier, first, and third waveforms to create a modulated signal package, and a first electrode electrically coupled to the modulation device and positioned substantially adjacent to the skin of the mammal, and adapted to apply the modulated signal package thereto.
摘要翻译：提供了用于经皮刺激哺乳动物的选定身体部位的装置和方法。该装置包括适于产生具有能够刺激第一预定身体部位的第一频率的第一波形的第一波形发生器，适于产生能够通过哺乳动物组织的第二频率的载波波形的第二波形发生器，以及第三波形发生器，其适于产生具有与所述第一波形的第三频率不同且与所述第一波形不相位的第三频率的第三波形，并且能够刺激第二预定体部。该装置还包括电耦合到第一，第二和第三波形发生器并且适于调制载波，第一和第三波形以产生调制信号封装的调制装置，以及电耦合到调制装置并基本上位于与哺乳动物的皮肤相邻，并且适于将调制信号包施加到其上。

22. 发明申请

US20060074272A1 Portable system for assessing urinary function and peforming endometrial ablation 审中-公开
标题翻译：便携式系统评估尿功能和子宫内膜消融
公开(公告)号：US20060074272A1
公开(公告)日：2006-04-06
申请号：US10959264
申请日：2004-10-06
申请人： Anthony DiUbaldi
发明人： Anthony DiUbaldi
IPC分类号： A61F2/00
CPC分类号： A61B5/202 , A61B5/205 , A61B18/04 , A61B2018/046 , A61B2090/064 , A61B2560/0443
摘要： A medical system is provided that includes a control device and a plurality of modules each capable of being removably coupled to the control device. When a first one of the plurality of modules is removably coupled to the control device, the medical system is capable of performing a test to assess urinary function, and when a second one of the plurality of modules is removably coupled to the control device, the medical system is capable of performing endometrial ablation.
摘要翻译：提供了一种医疗系统，其包括控制装置和多个模块，每个模块能够可移除地联接到控制装置。当多个模块中的第一个可移除地耦合到控制装置时，医疗系统能够执行用于评估尿功能的测试，并且当多个模块中的第二个模块可移除地耦合到控制装置时，医疗系统能够进行子宫内膜消融。

23. 发明申请

US20050277998A1 System and method for nerve stimulation 有权
标题翻译：神经刺激的系统和方法
公开(公告)号：US20050277998A1
公开(公告)日：2005-12-15
申请号：US11146522
申请日：2005-06-07
申请人： Michael Tracey , Anthony DiUbaldi
发明人： Michael Tracey , Anthony DiUbaldi
IPC分类号： A61B5/03 , A61B5/20 , A61N1/36 , A61N1/18
CPC分类号： A61N1/36007 , A61B5/20 , A61B5/202 , A61B5/205 , A61B5/6874 , A61B2562/028 , A61N1/0492 , A61N1/0514 , A61N1/0521 , A61N1/36017 , A61N1/36021 , G06F19/00
摘要： A system and method for stimulating a nerve, wherein the system includes a first waveform generator adapted to generate a first waveform having a frequency capable of stimulating a predetermined nerve of the mammal, a second waveform generator adapted to generate a carrier waveform having a frequency capable of passing through tissue of the mammal, a modulation device electrically coupled to the first and second waveform generators and adapted to modulate the first and carrier waveforms to create a modulated waveform, and an electrode electrically coupled to the modulation device and positioned substantially adjacent to skin of the mammal, and adapted to apply the modulated waveform thereto.
摘要翻译：一种用于刺激神经的系统和方法，其中所述系统包括适于产生具有能够刺激哺乳动物的预定神经的频率的第一波形的第一波形发生器，适于生成具有频率能力的载波波形的第二波形发生器通过哺乳动物的组织的调制装置，电耦合到第一和第二波形发生器并适于调制第一和载波波形以产生调制波形的调制装置，以及电耦合到调制装置并基本上邻近皮肤定位的电极并且适于将调制波形应用于其。

24. 发明授权

US08260439B2 Nerve stimulation patches and methods for stimulating selected nerves 有权
标题翻译：神经刺激斑块和刺激选择神经的方法
公开(公告)号：US08260439B2
公开(公告)日：2012-09-04
申请号：US11941508
申请日：2007-11-16
申请人： Anthony DiUbaldi , Michael Tracey , Rex O. Bare , Bradley Sargent , Stephen B. Wahlgren
发明人： Anthony DiUbaldi , Michael Tracey , Rex O. Bare , Bradley Sargent , Stephen B. Wahlgren
IPC分类号： A61N1/18
CPC分类号： A61N1/0456 , A61N1/0452 , A61N1/0492 , A61N1/0496 , A61N1/36007 , A61N1/36014 , A61N1/36021 , A61N1/375 , A61N1/3756 , A61N1/3758 , H05K3/281 , H05K2201/2018
摘要： A selective nerve stimulation patch includes a substrate having a top surface and a bottom surface, integrated components overlying the top surface of the substrate and being electrically interconnected with one another for generating at least one nerve stimulating signal, electrodes integrated into the substrate and exposed at the bottom surface thereof for applying the at least one nerve stimulating signal to a target nerve, a waterproof, breathable cover overlying the substrate and the integrated components, and a support flange surrounding the substrate and coupling the cover and the substrate together. The support flange has a top surface that slopes downwardly toward an outer perimeter thereof, and at least a portion of the cover conforms to the sloping top surface of the support flange. In one embodiment, the patch generates a high frequency waveform with properties such as amplitude, frequency and the like chosen so as to overcome tissue impedance and the stimulation threshold of the target nerve. The modulated waveform is the waveform obtained by modulating the carrier waveform by a pulse envelope.
摘要翻译：选择性神经刺激贴片包括具有顶表面和底表面的基底，整合的元件覆盖在基底的顶表面上并且彼此电互连以产生至少一种神经刺激信号，集成到基底中并暴露于其底表面用于将至少一个神经刺激信号施加到目标神经，覆盖在基底和集成部件上的防水透气盖，以及围绕基底并将盖和基底连接在一起的支撑凸缘。支撑凸缘具有朝向其外周向下倾斜的顶表面，并且盖的至少一部分符合支撑凸缘的倾斜顶表面。在一个实施例中，贴片产生具有所选择的诸如振幅，频率等特性的高频波形，以便克服组织阻抗和目标神经的刺激阈值。调制波形是通过用脉冲包络调制载波波形而获得的波形。

25. 发明授权

US08175718B2 Electrode patch and method for neurostimulation 有权
标题翻译：电极贴片和神经刺激方法
公开(公告)号：US08175718B2
公开(公告)日：2012-05-08
申请号：US11641617
申请日：2006-12-19
申请人： Stephen Wahlgren , Anthony DiUbaldi , John Young , Michael Freeman
发明人： Stephen Wahlgren , Anthony DiUbaldi , John Young , Michael Freeman
IPC分类号： A61N1/04
CPC分类号： A61N1/0456 , A61B5/04001 , A61B5/6833 , A61B2562/046 , A61N1/0476 , A61N1/0492 , A61N1/36014
摘要： A system for stimulating a nerve or nerves in a patient includes an electrode patch having an array of equally spaced concentric electrodes each having a central cathode and a concentrically surrounding anode. The electrode array patch is used to determine the location of the nerve or nerves to be stimulated by electrical pulses. Once the location of the nerve is determined, a concentric electrode patch having a central cathode and a concentrically surrounding anode is positioned at the optimal location on the patient's skin to effect neurostimulation. The concentric electrode patch may be removably affixed to the patient's skin by adhesive or magnets.
摘要翻译：用于刺激患者中的神经或神经的系统包括具有等间隔的同心电极阵列的电极贴片，每个均具有中心阴极和同心环绕的阳极。电极阵列贴片用于确定由电脉冲刺激的神经或神经的位置。一旦确定了神经的位置，具有中心阴极和同心环绕的阳极的同心电极贴片就位于病人皮肤上的最佳位置上，以进行神经刺激。同心电极贴片可以通过粘合剂或磁体可移除地固定到患者的皮肤上。

26. 发明申请

US20090132018A1 Nerve Stimulation Patches And Methods For Stimulating Selected Nerves 有权
标题翻译：神经刺激补丁和刺激所选神经的方法
公开(公告)号：US20090132018A1
公开(公告)日：2009-05-21
申请号：US11941508
申请日：2007-11-16
申请人： Anthony DiUbaldi , Michael Tracey , Rex O. Bare , Bradley Sargent , Stephen B. Wahlgren
发明人： Anthony DiUbaldi , Michael Tracey , Rex O. Bare , Bradley Sargent , Stephen B. Wahlgren
IPC分类号： A61N1/04
CPC分类号： A61N1/0456 , A61N1/0452 , A61N1/0492 , A61N1/0496 , A61N1/36007 , A61N1/36014 , A61N1/36021 , A61N1/375 , A61N1/3756 , A61N1/3758 , H05K3/281 , H05K2201/2018
摘要： A selective nerve stimulation patch includes a substrate having a top surface and a bottom surface, integrated components overlying the top surface of the substrate and being electrically interconnected with one another for generating at least one nerve stimulating signal, electrodes integrated into the substrate and exposed at the bottom surface thereof for applying the at least one nerve stimulating signal to a target nerve, a waterproof, breathable cover overlying the substrate and the integrated components, and a support flange surrounding the substrate and coupling the cover and the substrate together. The support flange has a top surface that slopes downwardly toward an outer perimeter thereof, and at least a portion of the cover conforms to the sloping top surface of the support flange. In one embodiment, the patch generates a high frequency waveform with properties such as amplitude, frequency and the like chosen so as to overcome tissue impedance and the stimulation threshold of the target nerve. The modulated waveform is the waveform obtained by modulating the carrier waveform by a pulse envelope.
摘要翻译：选择性神经刺激贴片包括具有顶表面和底表面的基底，整合的元件覆盖在基底的顶表面上并且彼此电互连以产生至少一种神经刺激信号，集成到基底中并暴露于其底表面用于将至少一个神经刺激信号施加到目标神经，覆盖在基底和集成部件上的防水透气盖，以及围绕基底并将盖和基底连接在一起的支撑凸缘。支撑凸缘具有朝向其外周向下倾斜的顶表面，并且盖的至少一部分符合支撑凸缘的倾斜顶表面。在一个实施例中，贴片产生具有所选择的诸如振幅，频率等特性的高频波形，以便克服组织阻抗和目标神经的刺激阈值。调制波形是通过用脉冲包络调制载波波形而获得的波形。

27. 发明申请

US20060195146A1 System and method for selectively stimulating different body parts 有权
标题翻译：选择性刺激不同身体部位的系统和方法
公开(公告)号：US20060195146A1
公开(公告)日：2006-08-31
申请号：US11344285
申请日：2006-01-31
申请人： Michael Tracey , Anthony DiUbaldi , Douglas Johns
发明人： Michael Tracey , Anthony DiUbaldi , Douglas Johns
IPC分类号： A61N1/18
CPC分类号： A61N1/36017 , A61N1/0492 , A61N1/0551 , A61N1/36003 , A61N1/36007 , A61N1/36014 , A61N1/36021
摘要： Devices and methods are provided for electrically stimulating a predetermined body part of a mammal. The method includes placing at least one electrode in proximity to the mammal's skin, injecting an electrically conductive gel into the body of the mammal so as to form a conductive gel pathway extending at least partially along a distance between the at least one electrode and the predetermined body part, and stimulating the predetermined body part by applying an electrical signal via the electrode that travels, at least in part, through the conductive gel pathway.
摘要翻译：提供了用于电刺激哺乳动物的预定身体部位的装置和方法。该方法包括将至少一个电极放置在哺乳动物的皮肤附近，将导电凝胶注射到哺乳动物的体内，以便形成至少部分地沿着至少一个电极与预定的电极之间的距离延伸的导电凝胶通路并通过经由至少部分地穿过导电凝胶路径行进的电极施加电信号来刺激预定的身体部位。

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