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21. 发明授权

US5154680A Pressure waveform monitor 失效
标题翻译：压力波形监视器
公开(公告)号：US5154680A
公开(公告)日：1992-10-13
申请号：US500063
申请日：1990-03-27
申请人： Gary M. Drzewiecki , Robert D. Butterfield , Edward J. Ciaccio
发明人： Gary M. Drzewiecki , Robert D. Butterfield , Edward J. Ciaccio
IPC分类号： A61B5/0215 , A61B5/021 , A61B5/024
CPC分类号： A61B5/021 , A61B5/02416
摘要： A pressure waveform monitor noninvasively monitors the pressure waveform in an underlying vessel such as an artery. The apparatus comprises at least one/continuous, relatively thin and narrow diaphragm mounted in a housing to be placed on the tissue overlying the vessel of interest. The diaphragm is longer than the diameter of the vessel for purposely monitoring pressure in the tissue adjacent the vessel of interest. The tonometer also comprises deformation sensor means for measuring deformation of the diaphragm both over the vessel and adjacent the vessel, and signal processing means for combining the waveform of the vessel as monitored by the part of the diaphragm over the vessel with the waveforms of adjacent tissue to accurately determine the actual pressure waveform in the vessel.
摘要翻译：压力波形监测器非侵入性地监测下面的血管（例如动脉）中的压力波形。该装置包括安装在壳体中的至少一个/连续，相对薄且窄的膜片，以被放置在覆盖感兴趣血管的组织上。隔膜比容器的直径长，用于有意识地监测邻近感兴趣血管的组织中的压力。眼压计还包括变形传感器装置，用于测量在容器和容器附近的膜片的变形，以及信号处理装置，用于将容器的部分隔膜监测的容器的波形与相邻组织的波形相组合以准确地确定容器中的实际压力波形。

22. 发明授权

US4710163A Detection of fluid flow faults in the parenteral administration of fluids 失效
标题翻译：检测流体肠胃外给药中的流体流动故障
公开(公告)号：US4710163A
公开(公告)日：1987-12-01
申请号：US872086
申请日：1986-06-06
申请人： Robert D. Butterfield
发明人： Robert D. Butterfield
IPC分类号： A61M1/00 , A61M5/00 , A61M5/168
CPC分类号： A61M5/16859 , A61M2205/702 , Y10S128/13
摘要： This invention is directed to a method and system for evaluating the fluid communication between a parenteral fluid delivery system and a patient's blood vessel. In accordance with the invention, one or more fluid flow pulses are applied to the fluid within the delivery system. Both positive and negative fluid flow pulses may be applied. The pressure response to the pulses under conditions of normal, unimpeded fluid flow is significantly different than the pressure response to such pulses when an infiltration or other fluid flow fault has occurred and this difference is used to detect fluid faults.
摘要翻译：本发明涉及一种用于评估肠胃外流体输送系统和患者血管之间的流体连通的方法和系统。根据本发明，一个或多个流体流动脉冲被施加到输送系统内的流体。可以施加正和负流体流动脉冲。在正常的，不受阻碍的流体流动的条件下，对脉冲的压力响应与当发生渗透或其它流体流动故障时对这种脉冲的压力响应显着不同，并且该差异用于检测流体故障。

23. 发明申请

US20120141306A1 FLUID PUMP WITH DISPOSABLE COMPONENT 有权
标题翻译：流体泵与可配置的组件
公开(公告)号：US20120141306A1
公开(公告)日：2012-06-07
申请号：US13306671
申请日：2011-11-29
申请人： Robert D. Butterfield
发明人： Robert D. Butterfield
IPC分类号： F04B17/00
CPC分类号： A61M5/14593 , A61M5/1413 , A61M5/14224 , A61M2005/14513 , A61M2205/106 , A61M2205/122 , A61M2205/128
摘要： A pump having a disposable fluid contacting portion which defines a fluid inlet and outlet and a fluid path there between is presented. The pump includes a drive portion configured to engage the disposable portion to cause fluid to be moved from the fluid inlet to the fluid outlet. The disposable portion is configured to be selectively coupled to the drive portion. The disposable portion includes a driven membrane which forms a portion of the fluid path, and the drive portion includes a drive membrane. The two membranes are vacuum coupled to each other, whereby movement of the drive membrane causes the driven membrane to move, causing fluid to be pumped through the disposable portion. The pump has particular utility in the medical field for moving fluid from a source to a patient. The pump may include features such as an air-trap, bubble detection, fluid flow controls, and pressure detection.
摘要翻译：提供具有限定流体入口和出口的一次性流体接触部分和其间的流体路径的泵。泵包括构造成接合一次性部分以使流体从流体入口移动到流体出口的驱动部分。一次性部分构造成选择性地联接到驱动部分。一次性部分包括形成流体路径的一部分的驱动膜，驱动部分包括驱动膜。两个膜彼此真空联接，由此驱动膜的移动导致从动膜移动，使得流体被泵送通过一次性部分。该泵在医疗领域具有特别的用途，用于将流体从源运动到患者。泵可以包括诸如空气阱，气泡检测，流体流量控制和压力检测的特征。

24. 发明授权

US08096186B2 Systems and methods for measuring fluid pressure within a disposable IV set connected to a fluid supply pump 有权
标题翻译：用于测量连接到流体供应泵的一次性IV组中的流体压力的系统和方法
公开(公告)号：US08096186B2
公开(公告)日：2012-01-17
申请号：US12731001
申请日：2010-03-24
申请人： Robert D. Butterfield
发明人： Robert D. Butterfield
IPC分类号： G01L9/12
CPC分类号： A61B5/6866 , A61B5/021 , A61M5/16854 , A61M2205/12 , A61M2205/3306 , A61M2205/3317 , G01L9/007 , G01L9/0072 , G01L9/0076 , G01L19/003
摘要： Systems and methods of measuring pressure of fluid in a disposable IV set connected to a fluid supply pump is disclosed. At least one sensing arrangement coupled to the fluid supply pump is provided. A chamber having a movable element is provided, the movable element configured to move in response to changes in fluid pressure within the disposable IV set and thereby cause a change in a sensed measurement variable associated with the sensing arrangement without contacting the sensing arrangement. A measuring signal indicative of the sensed measurement variable is generated. The fluid pressure within the disposable IV set is determined based on the measuring signal.
摘要翻译：公开了一种测量连接到流体供应泵的一次性IV组中的流体压力的系统和方法。提供耦合到流体供应泵的至少一个感测装置。提供具有可移动元件的室，所述可移动元件构造成响应于所述一次性IV组内的流体压力的变化而移动，并且因此引起与感测装置相关联的感测测量变量的变化而不接触感测装置。产生指示感测的测量变量的测量信号。一次性IV组内的流体压力基于测量信号确定。

25. 发明授权

US08082112B2 Apparatus and method for air-in-line detection 有权
标题翻译：空中在线检测装置及方法
公开(公告)号：US08082112B2
公开(公告)日：2011-12-20
申请号：US11563658
申请日：2006-11-27
申请人： Robert D. Butterfield , Allen B. Farquhar
发明人： Robert D. Butterfield , Allen B. Farquhar
IPC分类号： G01N31/00
CPC分类号： G01N29/38 , A61M5/14228 , A61M5/365 , G01N29/032 , G01N2291/02433 , Y10S128/13
摘要： The concentration of air or other agents in a fluid delivery line is determined by monitoring agent signals and processing those agent signals along with information regarding the age of each agent signal. The processor determines a primary agent concentration value based on the received agent signal values, with the primary agent concentration value determined by giving greater weight to more recent agent signal values. Where the primary agent concentration value exceeds a primary threshold value, an alarm signal may be activated. The processor also may determine a secondary agent concentration value, which may be determined from the actual agent signal values instead of the weighted agent signal values. Where the secondary agent concentration value exceeds a secondary threshold value, an alarm signal may be activated.
摘要翻译：流体输送管线中的空气或其他试剂的浓度通过监测试剂信号和处理那些试剂信号以及关于每个试剂信号的年龄的信息来确定。处理器基于接收的代理信号值来确定主代理集中值，其中通过对更近的代理信号值给予更大的权重来确定主代理集中度值。当主剂浓度值超过主要阈值时，可以激活报警信号。处理器还可以确定次级剂量浓度值，其可以根据实际代理信号值而不是加权代理信号值来确定。当副试剂浓度值超过次级阈值时，可以激活报警信号。

26. 发明授权

US08075514B2 Infusion data communication system 有权
标题翻译：输液数据通信系统
公开(公告)号：US08075514B2
公开(公告)日：2011-12-13
申请号：US10812723
申请日：2004-03-29
申请人： Robert D. Butterfield , David L. Schlotterbeck
发明人： Robert D. Butterfield , David L. Schlotterbeck
IPC分类号： A61M31/00
CPC分类号： A61M5/5086 , A61M5/142 , A61M5/172 , A61M2005/14208 , A61M2205/3569 , A61M2205/3592 , A61M2205/6018 , A61M2205/6054 , G06F19/00 , G06F19/326 , G06F19/3468 , G06Q50/22 , Y02A90/22 , Y02A90/26
摘要： An infusion data communication system provides a communication link among a fluid container, an infusion pump, and a patient through which identification data may be communicated. Data devices are located at the fluid container and the patient and conduct low frequency RF energy at a low power level containing the data into the medical fluid. The data-laden RF energy propagates through the medication fluid to data readers at the infusion pump which receives the RF energy and reads the data. A comparison is made to verify that the right medication is mounted to the infusion pump for administration to the right patient. RFID devices may be used for the data devices and readers. Pump programming data may also be propagated to the infusion pump from the container RFID tag. The RFID device at the patient may be writable and may be used to store a patient MAR.
摘要翻译：输注数据通信系统在流体容器，输液泵和患者之间提供通信链路，通过该通信链路可以传达识别数据。数据设备位于流体容器和患者身上，并将含有数据的低功率水平的低频RF能量传送到医用流体中。数据载入的RF能量通过药物流体传播到输注泵的数据读取器，其接收RF能量并读取数据。进行比较，以验证正确的药物是否安装到输液泵，以便管理给合适的患者。 RFID设备可以用于数据设备和读取器。泵编程数据也可以从容器RFID标签传播到输注泵。患者身上的RFID设备可以是可写的，并且可以用于存储患者MAR。

27. 发明授权

US06416291B1 Fluid flow resistance monitoring system 有权
标题翻译：流体阻力监测系统
公开(公告)号：US06416291B1
公开(公告)日：2002-07-09
申请号：US09602831
申请日：2000-06-23
申请人： Robert D. Butterfield , Allen B. Farquhar
发明人： Robert D. Butterfield , Allen B. Farquhar
IPC分类号： F04B4906
CPC分类号： A61M5/16859
摘要： Flow parameters in a fluid delivery assembly are determined by monitoring pressure responses and processing those responses along with information regarding the fluid flow. In one aspect, a processor controls the pump to pump flow quantities in accordance with a pseudorandom code. Portions of the resulting pressure signal sensed at the conduit is averaged, and the averaged values are then decoded in accordance with the pseudorandom code. An estimate of the equilibrium pressure is generated from the decoded average pressure values, while a summation of the pressure samples is generated from the undecoded pressure signals. The resistance to fluid flow of the system is determined from the estimated equilibrium pressure and pressure summation. For low flow rates, a processor controls the pump to pump fluid in a series of fluid boluses, with each fluid bolus delivered in the beginning of a separate timeslot. The equilibrium pressure is measured at the end of each timeslot, and a summation of the pressure samples is generated from the pressure signals. For high flow rates, the pump is controlled to vary the flow rate and the change in pressure is divided by the change in flow to directly determine the resistance. A resistance display continuously displays the resistance of the system. The pseudorandom coding and decoding can be used to filter out pressure-response crosstalk caused by multiple fluid infusion segments feeding into a common line.
摘要翻译：流体输送组件中的流量参数通过监测压力响应并且处理这些响应以及关于流体流动的信息来确定。在一个方面，处理器控制泵根据伪随机码来泵送流量。在导管处感测到的所得压力信号的部分被平均化，然后根据伪随机码对平均值进行解码。从解码的平均压力值产生平衡压力的估计，而从未解码的压力信号产生压力样本的总和。根据估计的平衡压力和压力求和确定系统对流体流动的阻力。对于低流量，处理器控制泵以一系列流体喷射泵送流体，每个流体推注在单独的时隙开始时传送。在每个时隙的末端测量平衡压力，并从压力信号产生压力样本的总和。对于高流量，泵被控制以改变流量，并且压力变化除以流量的变化以直接确定阻力。电阻显示连续显示系统的电阻。伪随机编码和解码可用于滤除由多个流体输注段馈送到公共线中引起的压力 - 响应串扰。

28. 发明授权

US5827223A Upstream occulsion detection system 失效
标题翻译：上游阴囊检测系统
公开(公告)号：US5827223A
公开(公告)日：1998-10-27
申请号：US522001
申请日：1995-08-31
申请人： Robert D. Butterfield
发明人： Robert D. Butterfield
IPC分类号： A61M5/00 , A61M5/168 , A61M31/00
CPC分类号： A61M5/16859 , A61M2005/16872
摘要： A pumping segment of a fluid line alternately in fluid communication with the upstream and downstream portions of the fluid line connects a fluid supply to a fluid receiver. A pressure sensor located downstream of the segment monitors the pressure during the segment's communication with the upstream and downstream ends. The pressure difference is used to establish a pressure threshold against which the average pressure is compared to determine if an upstream occlusion exists. Should the average pressure fall within a cautionary zone, the pump is reversed to examine the pressure difference once again. Based on the pressure difference during the reversal, a pressure threshold line may be adjusted thereby adapting to fluid administration conditions.
摘要翻译：交替地与流体管线的上游部分和下游部分流体连通的流体管线的泵送段将流体供应件连接到流体接收器。位于分段下游的压力传感器监测分段与上游和下游端的通信期间的压力。压力差被用于建立压力阈值，使平均压力与之对照以确定是否存在上游阻塞。如果平均压力落在警戒区内，则泵反转以再次检查压力差。基于反转期间的压力差，可以调整压力阈值线，从而适应流体管理条件。

29. 发明授权

US5716194A System for increasing flow uniformity 失效
标题翻译：增加流动均匀性的系统
公开(公告)号：US5716194A
公开(公告)日：1998-02-10
申请号：US305677
申请日：1994-09-12
申请人： Robert D. Butterfield , Gregory I. Voss
发明人： Robert D. Butterfield , Gregory I. Voss
IPC分类号： A61M5/168 , F04B43/08 , F04B43/12 , F04B49/06 , F04B49/00
CPC分类号： F04B43/082 , A61M5/16831 , F04B49/065 , F04B2203/0213
摘要： A pumping mechanism moving in movement increments is controlled to space those movement increments in direct proportion to the volume resulting from each movement increment. In a further aspect, movement increments are grouped to result in approximately equal volumes per group. The mechanism moves continuously through the movement increments in each group. Groups are spaced to result in approximately equal flow volumes per group. The number of groups decreases as the flow rate increases. The number of movement increments in each group and the volume of each group increase as the flow rate increases.
摘要翻译：控制以移动增量移动的抽吸机构，以便将这些运动增量与每个运动增量产生的体积成比例地放置。在另一方面，运动增量被分组以导致每组大致相等的体积。机构通过每组运动增量连续移动。组间隔以导致每组大致相等的流量。随着流量的增加，组数减少。每组中运动增量的数量和每组的体积随着流量的增加而增加。

30. 发明授权

US5439001A Flexible diaphragm tonometer 失效
标题翻译：柔性隔膜眼压计
公开(公告)号：US5439001A
公开(公告)日：1995-08-08
申请号：US154801
申请日：1993-11-17
申请人： Robert D. Butterfield , Gary M. Drzewiecki
发明人： Robert D. Butterfield , Gary M. Drzewiecki
IPC分类号： A61B5/0245 , A61B5/022 , A61B5/021
CPC分类号： A61B5/02007 , A61B5/02233
摘要： A pressure waveform monitor for non-invasively monitoring the pressure waveform inside a vessel, such as an artery, includes a flexible diaphragm extended across an opening of a container containing a fluid. The flexible diaphragm is placed against tissue surrounding an artery such that arterial pressure causes a deflection in the diaphragm. A deflection in the diaphragm causes the fluid to be redistributed throughout the container which is effectively divided into an array of volume compartments. The relative volume distribution is determined through impedance plethysmography. The diaphragm is maintained in a calibrated position by maintaining the array of volume compartments at relatively unchanged volumes. When the relative volumes remain essentially unchanged, calibrated tonometry is possible. The pressure within the container is then used to determine the pulse waveform and the pressure within the artery.
摘要翻译：用于非侵入性地监测诸如动脉的血管内的压力波形的压力波形监视器包括延伸穿过容纳流体的容器的开口的柔性隔膜。将柔性隔膜放置在围绕动脉的组织上，使得动脉压力导致隔膜中的偏转。隔膜中的偏转导致流体在整个容器中重新分布，其被有效地分成容积隔室的阵列。相对体积分布通过阻抗体积描记法确定。通过将体积隔室的阵列保持在相对不变的体积，将隔膜保持在校准位置。当相对体积基本保持不变时，校准的眼压测量是可能的。然后使用容器内的压力来确定脉搏波形和动脉内的压力。

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