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1. 发明授权

US07141037B2 Apparatus and method for air-in-line detection 有权
标题翻译：空中在线检测装置及方法
公开(公告)号：US07141037B2
公开(公告)日：2006-11-28
申请号：US10656424
申请日：2003-09-05
申请人： Robert D. Butterfield , Allen B. Farquhar
发明人： Robert D. Butterfield , Allen B. Farquhar
IPC分类号： A61M31/00 , A61M1/00
CPC分类号： G01N29/38 , A61M5/14228 , A61M5/365 , G01N29/032 , G01N2291/02433 , Y10S128/13
摘要： The concentration of air in a fluid delivery line is determined by monitoring output signals corresponding to the amount of air detected in the fluid and processing those signals along with information as to the time or total volume of fluid dispensed since each signal was produced. The processor determines an air concentration value based on the received signal values, with the air concentration value determined by giving greater weight to more recent signal values. Where the air concentration value exceeds a predetermined value, an alarm signal may be activated or fluid delivery may be stopped. The processor also may determine a secondary air concentration value, which may be determined from the raw signal values instead of the weighted signal values. Where the secondary air concentration value exceeds a second predetermined threshold, an alarm signal may be activated or fluid delivery may be stopped.
摘要翻译：流体输送管线中的空气浓度通过监测对应于在流体中检测到的空气量的输出信号并且处理这些信号以及关于由于每个信号产生而分配的流体的时间或总体积的信息来确定。处理器基于接收到的信号值来确定空气浓度值，其中通过对更近的信号值给予更大的权重来确定空气浓度值。当空气浓度值超过预定值时，可以启动报警信号或停止流体输送。处理器还可以确定二次空气浓度值，其可以根据原始信号值而不是加权信号值来确定。在二次空气浓度值超过第二预定阈值的情况下，可以启动报警信号或者可以停止流体输送。

2. 发明申请

US20080208484A1 APPARATUS AND METHOD FOR AIR-IN-LINE DETECTION 有权
标题翻译：用于空中在线检测的装置和方法
公开(公告)号：US20080208484A1
公开(公告)日：2008-08-28
申请号：US11563658
申请日：2006-11-27
申请人： Robert D. Butterfield , Allen B. Farquhar
发明人： Robert D. Butterfield , Allen B. Farquhar
IPC分类号： G01N33/00 , G08B21/00
CPC分类号： G01N29/38 , A61M5/14228 , A61M5/365 , G01N29/032 , G01N2291/02433 , Y10S128/13
摘要： The concentration of air or other agents in a fluid delivery line is determined by monitoring agent signals and processing those agent signals along with information regarding the age of each agent signal. The processor determines a primary agent concentration value based on the received agent signal values, with the primary agent concentration value determined by giving greater weight to more recent agent signal values. Where the primary agent concentration value exceeds a primary threshold value, an alarm signal may be activated. The processor also may determine a secondary agent concentration value, which may be determined from the actual agent signal values instead of the weighted agent signal values. Where the secondary agent concentration value exceeds a secondary threshold value, an alarm signal may be activated.
摘要翻译：流体输送管线中的空气或其他试剂的浓度通过监测试剂信号和处理那些试剂信号以及关于每个试剂信号的年龄的信息来确定。处理器基于接收的代理信号值来确定主代理集中值，其中通过对更近的代理信号值给予更大的权重来确定主代理集中度值。当主剂浓度值超过主要阈值时，可以激活报警信号。处理器还可以确定次级剂量浓度值，其可以根据实际代理信号值而不是加权代理信号值来确定。当副试剂浓度值超过次级阈值时，可以激活报警信号。

3. 发明授权

US08082112B2 Apparatus and method for air-in-line detection 有权
标题翻译：空中在线检测装置及方法
公开(公告)号：US08082112B2
公开(公告)日：2011-12-20
申请号：US11563658
申请日：2006-11-27
申请人： Robert D. Butterfield , Allen B. Farquhar
发明人： Robert D. Butterfield , Allen B. Farquhar
IPC分类号： G01N31/00
CPC分类号： G01N29/38 , A61M5/14228 , A61M5/365 , G01N29/032 , G01N2291/02433 , Y10S128/13
摘要： The concentration of air or other agents in a fluid delivery line is determined by monitoring agent signals and processing those agent signals along with information regarding the age of each agent signal. The processor determines a primary agent concentration value based on the received agent signal values, with the primary agent concentration value determined by giving greater weight to more recent agent signal values. Where the primary agent concentration value exceeds a primary threshold value, an alarm signal may be activated. The processor also may determine a secondary agent concentration value, which may be determined from the actual agent signal values instead of the weighted agent signal values. Where the secondary agent concentration value exceeds a secondary threshold value, an alarm signal may be activated.
摘要翻译：流体输送管线中的空气或其他试剂的浓度通过监测试剂信号和处理那些试剂信号以及关于每个试剂信号的年龄的信息来确定。处理器基于接收的代理信号值来确定主代理集中值，其中通过对更近的代理信号值给予更大的权重来确定主代理集中度值。当主剂浓度值超过主要阈值时，可以激活报警信号。处理器还可以确定次级剂量浓度值，其可以根据实际代理信号值而不是加权代理信号值来确定。当副试剂浓度值超过次级阈值时，可以激活报警信号。

4. 发明授权

US06416291B1 Fluid flow resistance monitoring system 有权
标题翻译：流体阻力监测系统
公开(公告)号：US06416291B1
公开(公告)日：2002-07-09
申请号：US09602831
申请日：2000-06-23
申请人： Robert D. Butterfield , Allen B. Farquhar
发明人： Robert D. Butterfield , Allen B. Farquhar
IPC分类号： F04B4906
CPC分类号： A61M5/16859
摘要： Flow parameters in a fluid delivery assembly are determined by monitoring pressure responses and processing those responses along with information regarding the fluid flow. In one aspect, a processor controls the pump to pump flow quantities in accordance with a pseudorandom code. Portions of the resulting pressure signal sensed at the conduit is averaged, and the averaged values are then decoded in accordance with the pseudorandom code. An estimate of the equilibrium pressure is generated from the decoded average pressure values, while a summation of the pressure samples is generated from the undecoded pressure signals. The resistance to fluid flow of the system is determined from the estimated equilibrium pressure and pressure summation. For low flow rates, a processor controls the pump to pump fluid in a series of fluid boluses, with each fluid bolus delivered in the beginning of a separate timeslot. The equilibrium pressure is measured at the end of each timeslot, and a summation of the pressure samples is generated from the pressure signals. For high flow rates, the pump is controlled to vary the flow rate and the change in pressure is divided by the change in flow to directly determine the resistance. A resistance display continuously displays the resistance of the system. The pseudorandom coding and decoding can be used to filter out pressure-response crosstalk caused by multiple fluid infusion segments feeding into a common line.
摘要翻译：流体输送组件中的流量参数通过监测压力响应并且处理这些响应以及关于流体流动的信息来确定。在一个方面，处理器控制泵根据伪随机码来泵送流量。在导管处感测到的所得压力信号的部分被平均化，然后根据伪随机码对平均值进行解码。从解码的平均压力值产生平衡压力的估计，而从未解码的压力信号产生压力样本的总和。根据估计的平衡压力和压力求和确定系统对流体流动的阻力。对于低流量，处理器控制泵以一系列流体喷射泵送流体，每个流体推注在单独的时隙开始时传送。在每个时隙的末端测量平衡压力，并从压力信号产生压力样本的总和。对于高流量，泵被控制以改变流量，并且压力变化除以流量的变化以直接确定阻力。电阻显示连续显示系统的电阻。伪随机编码和解码可用于滤除由多个流体输注段馈送到公共线中引起的压力 - 响应串扰。

5. 发明授权

US06616633B1 Apparatus and method for air-in-line detection 失效
标题翻译：空中在线检测装置及方法
公开(公告)号：US06616633B1
公开(公告)日：2003-09-09
申请号：US08933709
申请日：1997-09-19
申请人： Robert D. Butterfield , Allen B. Farquhar
发明人： Robert D. Butterfield , Allen B. Farquhar
IPC分类号： A61M100
CPC分类号： G01N29/38 , A61M5/14228 , A61M5/365 , G01N29/032 , G01N2291/02433 , Y10S128/13
摘要： The concentration of air or other agents in a fluid delivery line is determined by monitoring agent signals and processing those agent signals along with information regarding the age of each agent signal. The processor determines a primary agent concentration value based on the received agent signal values, with the primary agent concentration value determined by giving greater weight to more recent agent signal values. Where the primary agent concentration value exceeds a primary threshold value, an alarm signal may be activated. The processor also may determine a secondary agent concentration value, which may be determined from the actual agent signal values instead of the weighted agent signal values. Where the secondary agent concentration value exceeds a secondary threshold value, an alarm signal may be activated.
摘要翻译：流体输送管线中的空气或其他试剂的浓度通过监测试剂信号和处理那些试剂信号以及关于每个试剂信号的年龄的信息来确定。处理器基于接收的代理信号值来确定主代理集中值，其中通过对更近的代理信号值给予更大的权重来确定主代理集中度值。当主剂浓度值超过主要阈值时，可以激活报警信号。处理器还可以确定次级剂量浓度值，其可以根据实际代理信号值而不是加权代理信号值来确定。当副试剂浓度值超过次级阈值时，可以激活报警信号。

6. 发明授权

US6158965A Fluid flow resistance monitoring system 失效
公开(公告)号：US6158965A
公开(公告)日：2000-12-12
申请号：US688673
申请日：1996-07-30
申请人： Robert D. Butterfield , Allen B. Farquhar
发明人： Robert D. Butterfield , Allen B. Farquhar
IPC分类号： A61M5/142 , A61M5/168 , F04B49/06
CPC分类号： A61M5/16859
摘要： Flow parameters in a fluid delivery assembly are determined by monitoring pressure responses and processing those responses along with information regarding the fluid flow. In one aspect, a processor controls the pump to pump flow quantities in accordance with a pseudorandom code. Portions of the resulting pressure signal sensed at the conduit is averaged, and the averaged values are then decoded in accordance with the pseudorandom code. An estimate of the equilibrium pressure is generated from the decoded average pressure values, while a summation of the pressure samples is generated from the undecoded pressure signals. The resistance to fluid flow of the system is determined from the estimated equilibrium pressure and pressure summation. For low flow rates, a processor controls the pump to pump fluid in a series of fluid boluses, with each fluid bolus delivered in the beginning of a separate timeslot. The equilibrium pressure is measured at the end of each timeslot, and a summation of the pressure samples is generated from the pressure signals. For high flow rates, the pump is controlled to vary the flow rate and the change in pressure is divided by the change in flow to directly determine the resistance. A resistance display continuously displays the resistance of the system. The pseudorandom coding and decoding can be used to filter out pressure-response crosstalk caused by multiple fluid infusion segments feeding into a common line.

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