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21. 发明申请

US20070197817A1 Method for the preparation of 3-substituted-3'-hydroxypropionitrile 审中-公开
标题翻译： 3-取代-3'-羟基丙腈的制备方法
公开(公告)号：US20070197817A1
公开(公告)日：2007-08-23
申请号：US10592223
申请日：2004-03-13
申请人： Seong-Jin Kim , Jeong-Ho Song , Jin-Won Yun , Ho-Seong Lee , Ho-Cheol Kim
发明人： Seong-Jin Kim , Jeong-Ho Song , Jin-Won Yun , Ho-Seong Lee , Ho-Cheol Kim
IPC分类号： C07C253/16
CPC分类号： C07C253/16 , C07C253/00 , C07C255/12 , C07C255/13 , C07C255/15 , C07C255/20 , C07C255/31 , C07C255/36
摘要： The present invention relates to a method for the preparation of 3-substituted-3′-hydroxypropionitrile, more particularly, to a method for the preparation of 3-substituted-3′-hydroxypropionitrile which comprises performing ring opening of 1-substituted-ethylene oxide using sodium cyanide and citric acid in a range of pH 7.8˜8.3 to provide 3-substituted-3′-hydroxypropionitrile in high optical purity and with high yield.
摘要翻译：本发明涉及3-取代-3'-羟基丙腈的制备方法，更具体地说涉及制备3-取代-3'-羟基丙腈的方法，该方法包括进行1-取代环氧乙烷的开环使用氰化钠和柠檬酸在pH 7.8〜8.3的范围内，以高光学纯度和高产率提供3-取代-3'-羟基丙腈。

22. 发明申请

US20070185337A1 Process for the preparation of optically pure 4-hydroxy-2-oxo-1-pyrrolidine acetamide 审中-公开
标题翻译：制备光学纯的4-羟基-2-氧代-1-吡咯烷乙酰胺的方法
公开(公告)号：US20070185337A1
公开(公告)日：2007-08-09
申请号：US11596580
申请日：2005-05-25
申请人： Seong-Jin Kim , Chung-woo Lim , Chang Boo , Jung-hoon Oh , Ki Kim , Jae Lee , Duk Won
发明人： Seong-Jin Kim , Chung-woo Lim , Chang Boo , Jung-hoon Oh , Ki Kim , Jae Lee , Duk Won
IPC分类号： C07D207/04
CPC分类号： C07D207/273
摘要： A process for the preparation of chiral 4-hydroxy-2-oxo-1-pyrrolidine acetamide includes adding sodium cyanide together with citric acid to a solution of chiral epichlorohydrin to obtain chiral 3-chloro-2-hydroxypropionitrile by ring opening reaction of the chiral epichlorohydrin, reacting the obtained product with an alcohol containing hydrochloride gas to obtain chiral 4-chloro-3-hydroxybutyric acid ester, and reacting the obtained product in a presence of a base with glycinamide or with glycine ester accompanied by ammonolysis with ammonia to produce the targeted chiral 4-hydroxy-2-oxo-1-pyrrolidine acetamide.
摘要翻译：手性4-羟基-2-氧代-1-吡咯烷乙酰胺的制备方法包括将氰化钠与柠檬酸一起加入到手性表氯醇的溶液中，以通过手性的开环反应获得手性3-氯-2-羟基丙腈将得到的产物与含有盐酸气体的醇反应，得到手性4-氯-3-羟基丁酸酯，并使得到的产物在碱的存在下与甘氨酰胺或甘氨酸酯反应，伴随着氨的氨解，生成靶向手性4-羟基-2-氧代-1-吡咯烷乙酰胺。

23. 发明授权

US5869564A Ink composition 失效
标题翻译：墨水组成
公开(公告)号：US5869564A
公开(公告)日：1999-02-09
申请号：US360199
申请日：1994-12-21
申请人： Bradley Leonard Beach , Arthur Fred Diaz , Seong-Jin Kim , Dennis Richard McKean , Anna Marie Pearson , Jing Xiao Sun , Ajay Kanubhai Suthar , Richard Barber Watkins
发明人： Bradley Leonard Beach , Arthur Fred Diaz , Seong-Jin Kim , Dennis Richard McKean , Anna Marie Pearson , Jing Xiao Sun , Ajay Kanubhai Suthar , Richard Barber Watkins
IPC分类号： C09D11/00 , C08L83/04
CPC分类号： C09D11/326
摘要： The invention relates to an aqueous ink composition for use in ink jet printers comprising an aqueous carrier; a pigment; and a copolymer comprising a hydrophilic segment having an acidic function group, and a hydrophobic segment having a hydrolytically stable siloxyl substituent.
摘要翻译：本发明涉及一种用于包括水性载体的喷墨打印机的水性油墨组合物; 颜料; 和包含具有酸性官能团的亲水链段的共聚物，以及具有水解稳定的硅氧烷取代基的疏水链段。

24. 发明授权

US08101781B2 Process for the preparation of highly optical pure carvedilol 有权
标题翻译：制备高光学纯卡维地洛的方法
公开(公告)号：US08101781B2
公开(公告)日：2012-01-24
申请号：US12280684
申请日：2006-08-31
申请人： Seong-Jin Kim , Chang Woo Jong , Hyun Bin Kang , Byung Hyun Moon , Long Guo Quan , Duk Kwon Won , Kyung Yong Jin
发明人： Seong-Jin Kim , Chang Woo Jong , Hyun Bin Kang , Byung Hyun Moon , Long Guo Quan , Duk Kwon Won , Kyung Yong Jin
IPC分类号： A61K31/403 , C07D209/88
CPC分类号： C07D209/88 , C07D263/24 , C07D413/12 , Y02P20/55
摘要： The present invention relates to a process for the efficient preparation of highly optical pure chiral carvedilol. According to the present invention, a chiral oxazolidin-2-one or oxazolidin-2-thione having formula 2, produced from the reaction of N-protected 2-(2-methoxyphenoxy)ethylamine with a chiral glycidol derivative is used as a key intermediate for the preparation of the chiral carvedilol. Specifically, the process for the preparation of the chiral carvedilol comprises a) reacting a compound of formula 2 with a halogenation agent, a sulfonation agent or a mitsunobu reagent to activate a hydroxyl group of the compound of formula 2, followed by nucleophilic substitution reaction with 9H-4-hydroxy carbazole to produce a compound of formula 7, and b) subjecting the obtained compound of formula 7 to a deprotection reaction in a presence of an inorganic base to produce the targeted chiral carvedilol. The process of the present invention can be accomplished in a mild condition. The process neither requires any extraordinary purification procedure, nor involves decrease of optical purity. Therefore, the process of the present invention provides highly optical pure chiral carvedilol in simple and efficient manner.
摘要翻译：本发明涉及高效光学纯手性卡维地洛的高效制备方法。根据本发明，由N-保护的2-（2-甲氧基苯氧基）乙胺与手性缩水甘醇衍生物的反应生成的具有式2的手性恶唑烷-2-酮或恶唑烷-2-硫酮用作关键中间体用于制备手性卡维地洛。具体地说，制备手性卡维西洛的方法包括：a）使式2的化合物与卤化剂，磺化剂或mitsunobu试剂反应以活化式2化合物的羟基，然后与 9H-4-羟基咔唑制备式7的化合物，和b）在无机碱的存在下使得到的式7的化合物进行脱保护反应，得到目标的手性卡维地洛。本发明的方法可以在温和的条件下完成。该方法既不需要任何非凡的纯化程序，也不涉及降低光学纯度。因此，本发明的方法以简单有效的方式提供高光学纯手性卡维地洛。

25. 发明申请

US20110198560A1 SUBSTRATE FOR EPITAXIAL GROWTH, PROCESS FOR MANUFACTURING GaN-BASED SEMICONDUCTOR FILM, GaN-BASED SEMICONDUCTOR FILM, PROCESS FOR MANUFACTURING GaN-BASED SEMICONDUCTOR LIGHT EMITTING ELEMENT AND GaN-BASED SEMICONDUCTOR LIGHT EMITTING ELEMENT 有权
标题翻译：用于外延生长的衬底，用于制造GaN基半导体膜的工艺，基于GaN的半导体膜，用于制造GaN基半导体发光元件和基于GaN的半导体发光元件的工艺
公开(公告)号：US20110198560A1
公开(公告)日：2011-08-18
申请号：US12867787
申请日：2009-02-13
申请人： Hiroaki Okagawa , Hiromitsu Kudo , Teruhisa Nakai , Seong-Jin Kim
发明人： Hiroaki Okagawa , Hiromitsu Kudo , Teruhisa Nakai , Seong-Jin Kim
IPC分类号： H01L33/06 , H01L29/20 , H01L21/20 , H01L33/32 , H01L29/04
CPC分类号： C23C16/303 , C23C16/0236 , C30B25/18 , C30B29/403 , H01L21/02378 , H01L21/02381 , H01L21/02403 , H01L21/0242 , H01L21/0243 , H01L21/02433 , H01L21/0254 , H01L21/02658 , H01L21/02661 , H01L33/007 , H01L33/18 , H01L33/32
摘要： A substrate for epitaxial growth of the present invention comprises: a single crystal part comprising a material different from a GaN-based semiconductor at least in a surface layer part; and an uneven surface, as a surface for epitaxial growth, comprising a plurality of convex portions arranged so that each of the convex portions has three other closest convex portions in directions different from each other by 120 degrees and a plurality of growth spaces, each of which is surrounded by six of the convex portions, wherein the single crystal part is exposed at least on the growth space, which enables a c-axis-oriented GaN-based semiconductor crystal to grow from the growth space.
摘要翻译：本发明的用于外延生长的衬底包括：至少在表层部分包括不同于GaN基半导体的材料的单晶部分; 以及作为外延生长用表面的不平坦表面，包括多个凸部，其布置成使得每个凸部在彼此相差120度的方向上具有三个其他最接近的凸部，以及多个生长空间，其由六个凸部包围，其中至少在生长空间上露出单晶部分，这使得c轴取向的GaN基半导体晶体能够从生长空间生长。

26. 发明申请

US20110087781A1 REAL-TIME HARMFUL WEBSITE BLOCKING METHOD USING OBJECT ATTRIBUTE ACCESS ENGINE 失效
标题翻译：使用对象属性访问引擎的实时有效的网站阻塞方法
公开(公告)号：US20110087781A1
公开(公告)日：2011-04-14
申请号：US12972284
申请日：2010-12-17
申请人： Seong-Jin Kim
发明人： Seong-Jin Kim
IPC分类号： G06F15/16
CPC分类号： G06F17/30867 , G06F21/51 , G06F2221/2119 , G06F2221/2149 , H04L63/1441 , H04L63/1483
摘要： A real-time harmful website blocking method using an object attribute access engine is disclosed. In one embodiment, information about visual objects, currently being displayed on a screen by processes currently being executed, is obtained from a client. Attributes of the visual objects are extracted from the obtained information about the visual objects. Whether harmfulness is present is determined based on the extracted object attributes, and thus whether to block access to a server being connected thereto is decided. The client is requested to terminate a process for displaying the visual objects.
摘要翻译：公开了一种使用对象属性访问引擎的实时有害网站拦截方法。在一个实施例中，从客户端获得关于当前正在执行的进程正在屏幕上显示的可视对象的信息。从获得的关于视觉对象的信息中提取可视对象的属性。基于所提取的对象属性确定是否存在有害性，并且因此确定是否阻止对连接到其的服务器的访问。请求客户端终止显示可视对象的过程。

27. 发明申请

US20050104081A1 Semiconductor light emitting diode and method for manufacturing the same 审中-公开
标题翻译：半导体发光二极管及其制造方法
公开(公告)号：US20050104081A1
公开(公告)日：2005-05-19
申请号：US10858715
申请日：2004-06-01
申请人： Seong-Jin Kim , Yong-Seok Choi , Chang-Yen Kim , Young-Heon Han , Soon-Jae Yu
发明人： Seong-Jin Kim , Yong-Seok Choi , Chang-Yen Kim , Young-Heon Han , Soon-Jae Yu
IPC分类号： H01L33/10 , H01L33/12 , H01L33/22 , H01L33/32 , H01L33/38 , H01L33/44 , H01L33/62 , H01L33/00
CPC分类号： H01L33/20 , H01L24/73 , H01L33/0079 , H01L33/382 , H01L33/405 , H01L2224/32245 , H01L2224/32257 , H01L2224/48091 , H01L2224/48247 , H01L2224/73265 , H01L2224/8592 , H01L2924/01322 , H01L2924/10158 , H01L2924/12032 , H01L2924/181 , H01L2924/00014 , H01L2924/00 , H01L2924/00012
摘要： Provided is a light emitting diode including a base substrate having a via hole, a buffer layer having a via hole which is partially overlapped with the via hole of the base substrate, a first conductive contact layer formed on the buffer layer, a first clad layer formed on the second conductive contact layer, a light emitting layer formed on the first clad layer, a second clad layer formed on the light emitting layer, a second conductive contact layer formed on the second conductive clad layer, a first electrode formed on the second conductive contact layer, and a second electrode connected with the first conductive contact layer through the via hole.
摘要翻译：本发明提供一种发光二极管，包括具有通孔的基底基板，具有与基底基板的通孔部分重叠的通孔的缓冲层，形成在缓冲层上的第一导电接触层，第一覆盖层形成在第二导电接触层上的发光层，形成在第一覆盖层上的发光层，形成在发光层上的第二覆盖层，形成在第二导电覆盖层上的第二导电接触层，形成在第二导电接触层上的第二电极导电接触层和通过通孔与第一导电接触层连接的第二电极。

28. 发明授权

US06827950B2 Pharmaceutical composition comprising Aralia extracts 有权
标题翻译：含有Aralia提取物的药物组合物
公开(公告)号：US06827950B2
公开(公告)日：2004-12-07
申请号：US10219613
申请日：2002-08-15
申请人： Eun-Kyung Hong , Young-Shin Chung , Yeong-Bok Han , Yun Hui Choi , Seong-Jin Kim , Hae-Ri Kim , Bu-Hyeon Kang
发明人： Eun-Kyung Hong , Young-Shin Chung , Yeong-Bok Han , Yun Hui Choi , Seong-Jin Kim , Hae-Ri Kim , Bu-Hyeon Kang
IPC分类号： A61K3578
CPC分类号： A61K36/25
摘要： The present invention relates to Aralia extracts and a therapeutic agent comprising Aralia extracts as an active ingredient. The composition and therapeutic agent according to the present invention are effective in preventing cataract, delaying the development of cataract, and treating cataract. According to the present invention, extracts of Aralia are obtained by extraction with alcohol. Addition of myo-inositol or taurine to the extracts will result in a synergistic effect in the treatment of cataract. In addition, oral administration of beverages, galenicals, and nutraceuticals, which comprise Aralia extracts as an active ingredient, will be effective in prevention, delay and treatment of cataract caused by complications of diabetes. Aralia extracts will have the same effect in the case where they are used as an ophthalmic agent. They can also be used as an eye drop or an eye ointment.
摘要翻译：本发明涉及Aralia提取物和包含Aralia提取物作为活性成分的治疗剂。根据本发明的组合物和治疗剂可有效预防白内障，延缓白内障的发展和治疗白内障。根据本发明，通过用醇萃取获得Aralia的提取物。将肌醇或牛磺酸加入提取物将导致治疗白内障的协同效应。此外，含有Aralia提取物作为活性成分的饮料，盖仑制品和营养制品的口服给药将有效预防，延迟和治疗由糖尿病并发症引起的白内障。在将它们用作眼科剂的情况下，Aralia提取物将具有相同的效果。它们也可以用作滴眼剂或眼膏。

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