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    • 29. 发明授权
    • Therapeutic agents
    • 治疗剂
    • US06531148B1
    • 2003-03-11
    • US09719314
    • 2001-02-01
    • Tatsuji EnokiJun TomonoNobuto KoyamaKatsushige IkaiHiroaki SagawaIkunoshin Kato
    • Tatsuji EnokiJun TomonoNobuto KoyamaKatsushige IkaiHiroaki SagawaIkunoshin Kato
    • A61K4700
    • A61K31/7004A23L3/3535A23L3/3562A23L33/10A23V2002/00A61K31/35A61K31/351A61K31/357A23V2250/60A23V2250/608A23V2250/5024A23V2250/5036
    • Therapeutic or preventive agents for diseases requiring apoptosis induction, cancerous diseases, diseases requiring the inhibition of active oxygen production, those requiring the inhibition of nitrogen monoxide production, those requiring the inhibition of prostaglandin synthesis, those requiring the inhibition of synovial cell proliferation, those requiring the induction of heat shock protein production or those requiring the inhibition of &agr;-glycosidase, which contain as the active ingredient compounds selected from among compounds represented by general formula (I), (wherein X and Y are each H or CH2OH, provided that when X is CH2OH, Y is H, while when X is H, Y is CH2OH), those represented by general formula (II), (wherein R is a residue obtained by freeing a compound having an SH group from the SH group) and salts of both; and foods, drinks, cosmetics and so on, containing compounds selected from among compounds of general formula (I), those of general formula (II) and salts of both.
    • 需要细胞凋亡诱导的疾病,癌性疾病,需要抑制活性氧产生的疾病,需要抑制一氧化氮生成的那些的治疗或预防剂,需要抑制前列腺素合成的那些,需要抑制滑膜细胞增殖的那些,需要 诱导热休克蛋白产生或需要抑制α-糖苷酶的那些,其含有选自通式(I)表示的化合物中的活性成分,其中X和Y各自为H或CH 2 OH,条件是当 X是CH 2 OH,Y是H,而X是H,Y是CH 2 OH),由通式(II)表示的那些(其中R是从SH基团中释放具有SH基团的化合物获得的残基) 的两个 和食品,饮料,化妆品等,其含有选自通式(I)的化合物,通式(II)的化合物和二者的盐的化合物。