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    • 28. 发明授权
    • Pharmaceutical preparations of bioactive substances extracted from natural sources
    • 从天然来源提取生物活性物质的药物制剂
    • US06746695B1
    • 2004-06-08
    • US09578849
    • 2000-05-26
    • Michael Z. MartinMehdi Ashraf-KhorassaniLarry Taylor
    • Michael Z. MartinMehdi Ashraf-KhorassaniLarry Taylor
    • A61K3578
    • A61K36/48A61K36/185A61K36/32A61K36/61A61K36/67A61K36/734A61K36/77A61K2300/00
    • This invention relates to methods of extracting and purifying bioactive substances from various plants and herbs. More specifically the invention relates to methods of extracting and separating bioactive substances from various plants and herbs, such as Kava root, Byrsonima species, Aesculus californica, Crataegus mexicana, Simmondsia chinensis, Pfaffia species, Alternanthera repens, Bursera species, Turnera species, Perezia species, Heimia salicifolia, Psidium species, Enterlobium species, Ptychopetalum olacoides, Liriosma ovata, and Chaunochiton kappleri, using supercritical fluid extraction and/or fluorocarbon solvent extract. The present invention further relates to separation of bioactive substances contained in extracts using packed column supercritical fluid chromatography or HPLC where dense gas with or without modifiers is the mobile phase. The present invention also relates to pharmaceutical preparations and dietary supplements which may be prepared with the extracted bioactive substances and use of such pharmaceutical preparations and dietary supplements to treat various human ailments.
    • 本发明涉及从各种植物和草药中提取和纯化生物活性物质的方法。 更具体地说,本发明涉及从各种植物和草药中提取和分离生物活性物质的方法,例如卡瓦根,Byrsonima种,加利福尼亚cal ica,中华Cr ensis,Pfaffia物种,Alternanthera repens,Bursera物种,Turnera物种,Perezia物种 使用超临界流体萃取和/或碳氟化合物溶剂提取物,海蜇,鱼腥草属,ium藜种,ol,ides ides,,,。。。。。。。。。。。。。。。。。。。。。 本发明还涉及使用填充柱超临界流体色谱或HPLC分离萃取物中所含的生物活性物质,其中具有或不具有改性剂的致密气体是流动相。 本发明还涉及可以用提取的生物活性物质制备的药物制剂和膳食补充剂,以及使用这些药物制剂和膳食补充剂来治疗各种人类疾病。