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21. 发明专利

GB2110089A Device for sterilizing articles and environment 未知
公开(公告)号：GB2110089A
公开(公告)日：1983-06-15
申请号：GB8203683
申请日：1982-02-09
申请人： ALZA CORP
发明人： YUM SU II
IPC分类号： A01N25/26 , A01N25/34 , A01N35/02 , A61L2/18
摘要： A device for controlling the presence of unwanted microorganisms comprising a polymer comprising a probiocide that produces the biocide formaldehyde, an effervescent couple for evolving carbon dioxide, and optionally a surfactant.

22. 发明专利

ES2285704T3 FORMULACIONES NUEVAS PARA LA ADMINISTRACION TRANSDERMICA DE PERGOLIDA. 未知
公开(公告)号：ES2285704T3
公开(公告)日：2007-11-16
申请号：ES95929346
申请日：1996-06-07
申请人： ALZA CORP
发明人： YUM SU II , NELSON MELINDA K , CAMPBELL PATRICIA S
IPC分类号： A61K31/48 , A61M37/00 , A61K9/70 , A61K47/06 , A61K47/14 , A61K47/18 , A61P25/16
摘要： Composición para administrar pergolida a través de una membrana o superficie corporal a una velocidad terapéuticamente eficaz a un individuo que necesita una terapia con pergolida mediante permeación a través de la membrana o superficie corporal, comprendiendo la composición una cantidad de una sal farmacéuticamente aceptable de pergolida y un potenciador de la permeación que comprende una mezcla de monolaurato de glicerol y laurato de metilo.

23. 发明专利

DK0831827T3 未知
公开(公告)号：DK0831827T3
公开(公告)日：2007-09-10
申请号：DK95929346
申请日：1996-06-07
申请人： ALZA CORP
发明人： NELSON MELINDA K , YUM SU II , CAMPBELL PATRICIA S
IPC分类号： A61K31/48 , A61M37/00 , A61K9/70 , A61K47/06 , A61K47/14 , A61K47/18 , A61P25/16
摘要： Composition of matter for application to a body surface or membrane to administer pergolide by permeation through the body surface or membrane, the composition comprising pergolide to be administered, at a therapeutically effective rate, alone or in combination with a permeation enhancer or mixture. Also disclosed are drug delivery devices containing the pergolide or pergolide and enhancer composition and methods for the transdermal administration of the pergolide and pergolide/enhancer composition.

24. 发明专利

DE69334093T2 未知
公开(公告)号：DE69334093T2
公开(公告)日：2007-06-06
申请号：DE69334093
申请日：1993-02-19
申请人： ALZA CORP
发明人： WARRING JESSICA A , YUM SU II , SWEDLOW DAVID B , TASKOVICH LINA T , CORMIER MICHAEL J N , OLLERDESSEN ALBERT
IPC分类号： A61M35/00 , A61B5/00 , A61B5/024 , A61N1/30
摘要： A method for non-invasive monitoring of a characteristic of the blood of a patient, comprising: (i) providing a transdermal delivery device (10) comprising: (a) a backing member (20) that is substantially impermeable to a vaso-dilating agent; (b) a first adhesive layer (26) adjacent to one surface of the backing member; (c) a reservoir (22) adjacent to another surface of the backing member, the reservoir comprising sufficient vaso-dilating agent to induce local vaso-dilation in the skin of the patient to which the device may be attached; (d) a rate-controlling membrane (24) adjacent to a backing layer distal surface of the reservoir, (ii) attaching one exposed surface of the delivery device to a predetermined site on the patient's skin; (iii) mating an electro-optical sensor (40) to the first adhesive layer (26) of the transdermal delivery device, either before or after step (ii); (iv) thereafter permitting transdermal delivery of the vaso-dilating agent through the skin site at a rate dependent on the composition and thickness of the rate-controlling membrane (24) and on the diffusion co-efficient of the vaso-dilating agent within the rate-controlling membrane (24); and (v) concurrently monitoring a characteristic of the patient's blood with the sensor.

25. 发明专利

ES2171672T3 未知
公开(公告)号：ES2171672T3
公开(公告)日：2002-09-16
申请号：ES96914625
申请日：1996-05-13
申请人： ALZA CORP
发明人： LEE EUN SOO , YUM SU II
IPC分类号： A61K9/00 , A61K9/70 , A61K47/14 , A61L15/44
摘要： The present invention is directed to the transdermal administration of a drug together with a suitable amount of an acyl lactylate permeation enhancer. The invention includes a transdermal drug delivery device comprising a matrix adapted to be placed in drug- and- permeation enhancer-transmitting relation with a skin site. The matrix contains sufficient amounts of an acyl lactylate permeation enhancer and drug, in combination, to continuously administer drug to the systemic circulation of a patient at a therapeutically effective rate. The invention is also directed to compositions and methods for transdermal administration of a drug together with an acyl lactylate permeation enhancer, alone or in combination with other enhancers.

26. 发明专利

DK0828516T3 未知
公开(公告)号：DK0828516T3
公开(公告)日：2002-07-22
申请号：DK96914625
申请日：1996-05-13
申请人： ALZA CORP
发明人： LEE EUN SOO , YUM SU II
IPC分类号： A61K9/00 , A61K9/70 , A61K47/14 , A61L15/44
摘要： The present invention is directed to the transdermal administration of a drug together with a suitable amount of an acyl lactylate permeation enhancer. The invention includes a transdermal drug delivery device comprising a matrix adapted to be placed in drug- and- permeation enhancer-transmitting relation with a skin site. The matrix contains sufficient amounts of an acyl lactylate permeation enhancer and drug, in combination, to continuously administer drug to the systemic circulation of a patient at a therapeutically effective rate. The invention is also directed to compositions and methods for transdermal administration of a drug together with an acyl lactylate permeation enhancer, alone or in combination with other enhancers.

27. 发明专利

BR9608551A 未知
公开(公告)号：BR9608551A
公开(公告)日：1999-07-06
申请号：BR9608551
申请日：1996-05-30
申请人： ALZA CORP
发明人： BURKOTH TERRY L , TASKOVICH LINA T , MARZAN CRISOLOGO NIEVES , BESTE RUSSELL , HAMLIN RICHARD D , GALE ROBERT M , LEE EUN SOO , YUM SU II
IPC分类号： A61K9/00 , A61K9/70 , A61K47/14
摘要： Compositions, devices, and methods for transdermal administration of an active agent are disclosed using a novel dual permeation enhancer mixture comprising lauryl acetate and a monoglyceride, preferably glycerol monolaurate. The dual permeation enhancer mixture comprising lauryl acetate is a potent permeation enhancer and provides stable systems which are more readily characterized.

28. 发明专利

AU6476496A Novel formulations for transdermal delivery of pergolide 未知
公开(公告)号：AU6476496A
公开(公告)日：1996-12-30
申请号：AU6476496
申请日：1996-06-07
申请人： ALZA CORP
发明人： YUM SU II , NELSON MELINDA K , CAMPBELL PATRICIA S
IPC分类号： A61M37/00 , A61K9/70 , A61K31/48 , A61K47/06 , A61K47/14 , A61K47/18 , A61P25/16
摘要： Composition of matter for application to a body surface or membrane to administer pergolide by permeation through the body surface or membrane, the composition comprising pergolide to be administered, at a therapeutically effective rate, alone or in combination with a permeation enhancer or mixture. Also disclosed are drug delivery devices containing the pergolide or pergolide and enhancer composition and methods for the transdermal administration of the pergolide and pergolide/enhancer composition.

29. 发明专利

ZA937452B Delayed onset transdermal delivery device 未知
公开(公告)号：ZA937452B
公开(公告)日：1994-06-07
申请号：ZA937452
申请日：1993-10-07
申请人： ALZA CORP
发明人： LEE EUN SOO , YUM SU II , THEEUWES FELIX
IPC分类号： A61K9/70 , A61K47/48 , A61K

30. 发明专利

ZA923663B SKIN PERMEATION ENHANCER COMPOSITIONS USING GLYCEROL MONOLINOLEATE 未知
公开(公告)号：ZA923663B
公开(公告)日：1993-01-27
申请号：ZA923663
申请日：1992-05-20
申请人： ALZA CORP
发明人： LEE EUN SOO , EUN SOO LEE , NEDBERGE DIANE E , DIANE E NEDBERGE , YUM SU II , SU II YUM
IPC分类号： A61K9/00 , A61K9/127 , A61K9/70 , A61K47/14 , A61K

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