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11. 发明授权

US06469300B1 Apparatus and method for injecting a concentrated fluorescent dye into a sealed air-conditioning system 有权
标题翻译：将浓缩荧光染料注入密封空调系统的装置和方法
公开(公告)号：US06469300B1
公开(公告)日：2002-10-22
申请号：US09654867
申请日：2000-09-05
申请人： Phil Trigiani , Tony Ferraro
发明人： Phil Trigiani , Tony Ferraro
IPC分类号： G01T1161
CPC分类号： B60H1/00585 , F24F11/36 , F25B45/00 , F25B2345/001 , F25B2500/222
摘要： An apparatus and a method for injecting a concentrated fluorescent dye into a sealed air-conditioning system prior to the system going into service are revealed. The apparatus is made of a heated reservoir connected to a heated hose which is connected to a heated injector. The method involves heating a fluorescent dye to form a molten liquid fluorescent dye, maintaining the liquid fluorescent dye at a constant temperature and viscosity and injecting the liquid fluorescent dye into a component of a sealed air-conditioning system prior to the system going into service.
摘要翻译：揭示了在系统投入使用之前将浓缩荧光染料注入密封空调系统的装置和方法。该设备由连接到加热软管的加热储存器制成，该加热软管连接到加热的喷射器。该方法包括加热荧光染料以形成熔融液体荧光染料，将液体荧光染料保持在恒定温度和粘度，并在系统投入使用之前将液体荧光染料注入到密封空调系统的部件中。

12. 发明授权

US06444997B1 Radiation image read-out apparatus 有权
公开(公告)号：US06444997B1
公开(公告)日：2002-09-03
申请号：US09808103
申请日：2001-03-15
申请人： Yuji Isoda
发明人： Yuji Isoda
IPC分类号： G01T1161
摘要： A radiation image read-out apparatus including a lens array and a line sensor for reading an image recorded on a stimulable phosphor sheet provides a read-out image of high quality which is free from a spurious pattern due to non-aperture regions of the lens array. A first memory stores an image signal representing the image recorded on the stimulable phosphor sheet. Spurious pattern signal calculating means calculates a spurious pattern signal based on positions of the non-aperture regions on the lens array. The spurious pattern signal is stored in a second memory. Image modification means reads the image signal and the spurious pattern signal from the first and second memories to calculate a processed image signal free from any spurious pattern signal on a pixel-by-pixel basis. The spurious pattern signal may instead be obtained by causing the apparatus to read a uniform radiation image recorded on the stimulable phosphor sheet.

13. 发明授权

US06429432B1 Gamma radiation isolation shield and method of use 有权
标题翻译：伽玛辐射隔离屏蔽及使用方法
公开(公告)号：US06429432B1
公开(公告)日：2002-08-06
申请号：US09449787
申请日：1999-11-26
申请人： Colin J. McNaught , Douglas Arthur Kieper , Benjamin Lawrence Welch , Lee Holland Fairchild
发明人： Colin J. McNaught , Douglas Arthur Kieper , Benjamin Lawrence Welch , Lee Holland Fairchild
IPC分类号： G01T1161
CPC分类号： G21F3/00 , G01T1/1648
摘要： An adjustable gamma radiation isolation shield that effectively shields the gamma camera from potentially interfering radiation emitted from sources other than the particular anatomical portion under examination. The shield is placed adjacent to the breast or other body portion under examination on the side thereof opposite that addressed by the gamma camera i.e., at about 90° to the viewing angle of the camera. The shield includes a first gamma ray permeable layer capable of absorbing fluorescent low energy radiation produced by a second adjacent gamma radiation absorbing layer or any other source. In operation, the breast is located between the gamma camera/detector and shield. Gamma radiation emitted by the radiopharmaceutical-containing breast impinges the gamma camera for measurement and simultaneously penetrates the gamma permeable layer and is absorbed by the gamma radiation absorbing layer. Fluorescence produced upon absorption of the gamma radiation is inhibited from reintroduction into the gamma camera by absorption in the first gamma permeable layer that absorbs this secondary radiation. Gamma or other potentially interfering radiation entering the system from beyond the gamma radiation absorbing layer is similarly absorbed and any secondary fluorescent radiation produced therein absorbed by the first gamma permeable layer.
摘要翻译：一个可调节的伽马辐射隔离屏蔽，可有效屏蔽伽马相机免受从被检查的特定解剖部分以外的其他光源发射的潜在干扰辐射。护罩被放置在与伽马照相机相对的一侧相对于被检查的乳房或其他身体部分附近，即与摄像机的视角成约90°。屏蔽包括能够吸收由第二相邻伽马射线吸收层或任何其它源产生的荧光低能辐射的第一伽马射线可渗透层。在操作中，乳房位于伽马相机/检测器和屏蔽之间。由含放射性药物的乳腺发射的γ射线照射用于测量的γ照相机并同时穿透γ透射层并被伽马射线吸收层吸收。通过在吸收该二次辐射的第一γ透射层中的吸收来抑制伽马射线吸收时产生的荧光被再次引入γ照相机。 γ射线吸收层之外进入系统的γ或其他潜在干扰辐射被类似地吸收，并且其中产生的任何二次荧光辐射由第一γ透射层吸收。

14. 发明授权

US06403957B1 Nucleic acid reading and analysis system 失效
标题翻译：核酸读取和分析系统
公开(公告)号：US06403957B1
公开(公告)日：2002-06-11
申请号：US09690191
申请日：2000-10-16
申请人： Stephen P. A. Fodor , J. Leighton Read , Lubert Stryer , Michael C. Pirrung
发明人： Stephen P. A. Fodor , J. Leighton Read , Lubert Stryer , Michael C. Pirrung
IPC分类号： G01T1161
CPC分类号： C08G69/00 , B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00619 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00639 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01L7/52 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07C229/14 , C07C229/16 , C07D263/44 , C07D317/62 , C07H19/04 , C07H19/10 , C07H21/00 , C07K1/04 , C07K1/042 , C07K1/045 , C07K1/047 , C07K1/062 , C07K7/06 , C07K17/06 , C07K17/14 , C12Q1/6809 , C12Q1/6816 , C12Q1/6837 , C12Q1/6874 , C40B40/06 , C40B40/10 , C40B60/14 , C40B80/00 , G01N15/1475 , G01N21/253 , G01N21/6428 , G01N21/6452 , G03F7/00 , G03F7/26 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , H01L25/50 , H01L2924/0002 , Y02P20/55 , Y10S435/961 , Y10S435/968 , Y10S435/969 , Y10S435/973 , Y10S436/807 , Y10S436/809 , Y10T428/31971 , Y10T436/2575 , H01L2924/00
摘要： A method and apparatus for preparation of a substrate containing a plurality of sequences. Photoremovable groups are attached to a surface of a substrate. Selected regions of the substrate are exposed to light so as to activate the selected areas. A monomer, also containing a photoremovable group; is provided to the substrate to bind at the selected areas. The process is repeated using a variety of monomers such as amino acids until sequences of a desired length are obtained. Detection methods and apparatus are also disclosed.
摘要翻译：一种用于制备含有多个序列的底物的方法和装置。可除光组附着在基片的表面上。将基板的选定区域暴露于光以便激活所选择的区域。也含有可光除去基团的单体; 被提供到衬底以在所选择的区域处结合。使用各种单体如氨基酸重复该过程，直到获得所需长度的序列。还公开了检测方法和装置。

15. 发明授权

US06392235B1 Coded-aperture system for planar imaging of volumetric sources 有权
标题翻译：用于体积源平面成像的编码孔径系统
公开(公告)号：US06392235B1
公开(公告)日：2002-05-21
申请号：US09504417
申请日：2000-02-15
申请人： Harrison H. Barrett , Eric Clarkson , Donald W. Wilson
发明人： Harrison H. Barrett , Eric Clarkson , Donald W. Wilson
IPC分类号： G01T1161
CPC分类号： G01T1/295
摘要： A coded aperture is placed in proximity of a patient's body and a 2D coded image is acquired in conventional manner. The basic data-acquisition geometry is similar to that used in various coded-aperture systems. According to one aspect of the invention, additional coded images are acquired with different spacings between the aperture and the detector. Alternatively, additional coded images could be acquired with multiple movable apertures or by varying the location of the aperture relative to a patient. Another aspect of the invention resides in the recognition that presently available computer algorithms can process these multiple coded images in such a way as to estimate the integrals of the 3D object over a set of parallel cylindrical tubes extending through the volume of the target object. Such “tube integrals” can be thought of as the output of an ideal collimator where the sensitivity is confined to a tubular region of constant cross-section.
摘要翻译：编码孔径放置在患者身体附近，并且以常规方式获取2D编码图像。基本的数据采集几何与在各种编码孔径系统中使用的几何相似。根据本发明的一个方面，在孔径和检测器之间采用不同间隔的附加编码图像。或者，可以利用多个可移动孔或通过改变孔相对于患者的位置来获取附加编码图像。本发明的另一方面在于认识到目前可用的计算机算法可以以这样的方式处理这些多个编码图像，以便通过延伸穿过目标对象的体积的一组平行圆柱形管来估计3D对象的积分。这种“管积分”可以被认为是理想准直器的输出，其中灵敏度被限制在恒定横截面的管状区域。

16. 发明授权

US06249003B1 Imaging attenuation correction method employing multiple energy scan masks and windows 失效
标题翻译：使用多个能量扫描掩模和窗口的成像衰减校正方法
公开(公告)号：US06249003B1
公开(公告)日：2001-06-19
申请号：US09336665
申请日：1999-06-18
申请人： Randall F. Culp
发明人： Randall F. Culp
IPC分类号： G01T1161
CPC分类号： G01T1/1648
摘要： An apparatus for generating gamma transmission and gamma emission images simultaneously includes a camera and a line transmission source of gamma radiation disposed on opposite sides of an imaging area in which a patient lies. The line detector moves along a path that substantially traverses the field of view of the gamma camera. As the gamma camera moves an acceptance region and a mask region are electronically defined and moved across the camera's field of view. Photons striking the camera are categorized according to their energy and the region of impingement. The categorization defined an emission image, a transmission image and a crosstalk image. The transmission and crosstalk images are combined to form a corrected transmission image that then is used along with the emission image to produce and image of the patient.
摘要翻译：用于同时产生伽马透射和伽马发射图像的装置包括相机和设置在患者所在的成像区域的相对侧上的伽马射线的线传输源。线检测器沿着基本上穿过伽马照相机的视场的路径移动。随着伽马照相机移动接受区域，并且电子定义并且通过照相机的视野移动掩模区域。触发相机的光子根据其能量和冲击区域进行分类。分类定义了发射图像，透射图像和串扰图像。传输和串扰图像被组合以形成校正的传输图像，然后与发射图像一起使用以产生和图像患者。

17. 发明授权

US06195412B1 Confocal coded aperture imaging 失效
标题翻译：共聚焦编码孔径成像
公开(公告)号：US06195412B1
公开(公告)日：2001-02-27
申请号：US09266055
申请日：1999-03-10
申请人： Kenneth William Tobin, Jr. , Clarence E. Thomas, Jr.
发明人： Kenneth William Tobin, Jr. , Clarence E. Thomas, Jr.
IPC分类号： G01T1161
CPC分类号： G01T1/295
摘要： A method for imaging a target volume comprises the steps of: radiating a small bandwidth of energy toward the target volume; focusing the small bandwidth of energy into a beam; moving the target volume through a plurality of positions within the focused beam; collecting a beam of energy scattered from the target volume with a non-diffractive confocal coded aperture; generating a shadow image of said aperture from every point source of radiation in the target volume; and, reconstructing the shadow image into a 3-dimensional image of the every point source by mathematically correlating the shadow image with a digital or analog version of the coded aperture. The method can comprise the step of collecting the beam of energy scattered from the target volume with a Fresnel zone plate.
摘要翻译：用于对目标体积进行成像的方法包括以下步骤：向目标体积辐射小的能量带宽; 将能量的小带宽集中在光束中; 通过聚焦光束内的多个位置移动目标体积; 以非衍射共焦编码孔径收集从目标体积散射的能量束; 从目标体积中的每个点辐射源产生所述孔径的阴影图像; 并且通过数字地将阴影图像与编码孔径的数字或模拟版本相关联，将影子图像重建成每个点源的3维图像。该方法可以包括用菲涅耳带板收集从目标体积散射的能量束的步骤。

18. 发明授权

US06774371B2 Method and apparatus for a multi-planar imaging system 有权
标题翻译：多平面成像系统的方法和装置
公开(公告)号：US06774371B2
公开(公告)日：2004-08-10
申请号：US09989228
申请日：2001-11-20
申请人： Jody Garrard , Jeffrey Hallett
发明人： Jody Garrard , Jeffrey Hallett
IPC分类号： G01T1161
CPC分类号： G01T1/166 , A61B6/037 , A61B6/4258 , G01T1/1644
摘要： The invention comprises a system and method for multi-planar imaging using a plurality of detectors coupled to an ECDAS. Each of the plurality of detectors is independently positionable and configurable to acquire image data of one or more patients, and is controlled by the ECDAS. The ECDAS operates in at least two modes. A first mode, the ECDAS configures the plurality of detectors to collect image data for a single procedure of a single patient. A second mode, ECDAS configures the plurality of detectors to collect image data of a plurality of patients simultaneously.
摘要翻译：本发明包括使用耦合到ECDAS的多个检测器进行多平面成像的系统和方法。多个检测器中的每一个独立地可定位和配置以获取一个或多个患者的图像数据，并由ECDAS控制。 ECDAS至少运行两种模式。第一模式，ECDAS配置多个检测器以收集单个患者的单个过程的图像数据。第二模式，ECDAS配置多个检测器以同时收集多个患者的图像数据。

19. 发明授权

US06740882B2 Dedicated apparatus and method for emission mammography 失效
公开(公告)号：US06740882B2
公开(公告)日：2004-05-25
申请号：US10278096
申请日：2002-10-23
申请人： Irving Weinberg
发明人： Irving Weinberg
IPC分类号： G01T1161
CPC分类号： A61B6/0414 , A61B6/4258 , A61B6/502 , A61B6/547 , G01T1/1642
摘要： The present invention is an apparatus for examining a body part. The apparatus comprises a mechanism for immobilizing and compressing the body part. The apparatus also comprises a mechanism for providing an internal anatomical image of the body part and a mechanism for detecting single gamma-rays emitted by a radiotracer infiltrated into the body part. The detecting mechanism is disposed in an adjacent relationship with the mechanism for providing an internal anatomic image so that the body part remains in the same position during and between anatomic and radiotracer imaging. In one embodiment, the detecting mechanism includes a detector module disposed on one side of the immobilizing mechanism. The detector module preferably has at least one array of gamma ray sensitive material in communication with a position detector. In another embodiment, the detecting mechanism includes a pair of detector modules disposed one on each side of the immobilizing mechanism. The present invention is also an apparatus for examining a body part which comprises a mechanism for immobilizing and compressing the body part and a mechanism for providing a stereotactic internal anatomical image of the body part. The apparatus also comprises a mechanism for providing a stereotactic physiological image of the body part in an adjacent relationship with the mechanism for providing an internal anatomic image such that the body part remains in the same position during and between stereotactic anatomic and radiotracer imaging.

20. 发明授权

US06677584B2 Manufacturing fluid including fluorescent dye penetrant and method for using to make components 失效
标题翻译：包括荧光染料渗透剂在内的制造流体和用于制造组分的方法
公开(公告)号：US06677584B2
公开(公告)日：2004-01-13
申请号：US09886996
申请日：2001-06-25
申请人： Tom Yonushonis
发明人： Tom Yonushonis
IPC分类号： G01T1161
CPC分类号： G01N21/6447 , G01N21/91 , G01N2021/646
摘要： A reliable and cost-effective method and composition is provided for inspecting manufactured components and detecting defects therein. In particularly, a method is provided for optically detecting defects in manufactured components during the manufacturing process by the incorporation of a fluorescent dye into a manufacturing fluid.
摘要翻译：提供了可靠且具有成本效益的方法和组合来检查制造的部件并检测其中的缺陷。特别地，提供了一种通过将荧光染料结合到制造流体中来在制造过程中光学检测制造部件中的缺陷的方法。

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