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1. 发明授权

US06429432B1 Gamma radiation isolation shield and method of use 有权
标题翻译：伽玛辐射隔离屏蔽及使用方法
公开(公告)号：US06429432B1
公开(公告)日：2002-08-06
申请号：US09449787
申请日：1999-11-26
申请人： Colin J. McNaught , Douglas Arthur Kieper , Benjamin Lawrence Welch , Lee Holland Fairchild
发明人： Colin J. McNaught , Douglas Arthur Kieper , Benjamin Lawrence Welch , Lee Holland Fairchild
IPC分类号： G01T1161
CPC分类号： G21F3/00 , G01T1/1648
摘要： An adjustable gamma radiation isolation shield that effectively shields the gamma camera from potentially interfering radiation emitted from sources other than the particular anatomical portion under examination. The shield is placed adjacent to the breast or other body portion under examination on the side thereof opposite that addressed by the gamma camera i.e., at about 90° to the viewing angle of the camera. The shield includes a first gamma ray permeable layer capable of absorbing fluorescent low energy radiation produced by a second adjacent gamma radiation absorbing layer or any other source. In operation, the breast is located between the gamma camera/detector and shield. Gamma radiation emitted by the radiopharmaceutical-containing breast impinges the gamma camera for measurement and simultaneously penetrates the gamma permeable layer and is absorbed by the gamma radiation absorbing layer. Fluorescence produced upon absorption of the gamma radiation is inhibited from reintroduction into the gamma camera by absorption in the first gamma permeable layer that absorbs this secondary radiation. Gamma or other potentially interfering radiation entering the system from beyond the gamma radiation absorbing layer is similarly absorbed and any secondary fluorescent radiation produced therein absorbed by the first gamma permeable layer.
摘要翻译：一个可调节的伽马辐射隔离屏蔽，可有效屏蔽伽马相机免受从被检查的特定解剖部分以外的其他光源发射的潜在干扰辐射。护罩被放置在与伽马照相机相对的一侧相对于被检查的乳房或其他身体部分附近，即与摄像机的视角成约90°。屏蔽包括能够吸收由第二相邻伽马射线吸收层或任何其它源产生的荧光低能辐射的第一伽马射线可渗透层。在操作中，乳房位于伽马相机/检测器和屏蔽之间。由含放射性药物的乳腺发射的γ射线照射用于测量的γ照相机并同时穿透γ透射层并被伽马射线吸收层吸收。通过在吸收该二次辐射的第一γ透射层中的吸收来抑制伽马射线吸收时产生的荧光被再次引入γ照相机。 γ射线吸收层之外进入系统的γ或其他潜在干扰辐射被类似地吸收，并且其中产生的任何二次荧光辐射由第一γ透射层吸收。

2. 发明申请

US20100016865A1 Gamma guided stereotactic localization system 失效
标题翻译：伽玛引导立体定位系统
公开(公告)号：US20100016865A1
公开(公告)日：2010-01-21
申请号：US12218602
申请日：2008-07-16
申请人： Douglas A. Kieper , Benjamin Lawrence Welch , Lee Holland Fairchild
发明人： Douglas A. Kieper , Benjamin Lawrence Welch , Lee Holland Fairchild
IPC分类号： A61B19/00
CPC分类号： A61B6/4258 , A61B34/20 , A61B90/361 , A61B2090/371 , A61B2090/392
摘要： A stereotactic gamma-guided localization system for imaging a suspected cancer and guiding a physician in the removal of tissue samples for biopsy. The gamma-guided localization system includes a three step procedure including localization, correlation, and verification. The localization system includes a gamma camera with a set of slant-hole collimators for producing stereo images of a region of interest. A positioning system including a fiducial marker is placed adjacent to the object to be imaged and held rigidly in place to provide correlation of the location of the region of interest relative to the fiducial marker. A gamma emitting marker is then positioned at the calculated location of the region of interest and imaged to verify that that the calculated position corresponds to the actual location. The positioning system can then be used to accurately position and support any other hardware that needs to be positioned at the region of interest.
摘要翻译：一种用于成像疑似癌症并引导医师去除组织样本用于活组织检查的立体定向伽马引导定位系统。伽马引导定位系统包括三步骤程序，包括定位，相关和验证。定位系统包括具有一组倾斜准直仪的伽马相机，用于产生感兴趣区域的立体图像。将包括基准标记的定位系统放置在与要成像的对象相邻并且刚性地保持就位以提供相对于基准标记的感兴趣区域的位置的相关性。然后将伽马发射标记物定位在所计算的感兴趣区域的位置并成像以验证所计算的位置对应于实际位置。然后可以使用定位系统来精确定位和支持需要定位在感兴趣区域的任何其他硬件。

3. 发明授权

US08249693B2 Gamma guided stereotactic localization system 失效
标题翻译：伽玛引导立体定位系统
公开(公告)号：US08249693B2
公开(公告)日：2012-08-21
申请号：US12218602
申请日：2008-07-16
申请人： Douglas A. Kieper , Benjamin Lawrence Welch , Lee Holland Fairchild
发明人： Douglas A. Kieper , Benjamin Lawrence Welch , Lee Holland Fairchild
IPC分类号： A61B6/00
CPC分类号： A61B6/4258 , A61B34/20 , A61B90/361 , A61B2090/371 , A61B2090/392
摘要： A stereotactic gamma-guided localization system for imaging a suspected cancer and guiding a physician in the removal of tissue samples for biopsy. The gamma-guided localization system includes a three step procedure including localization, correlation, and verification. The localization system includes a gamma camera with a set of slant-hole collimators for producing stereo images of a region of interest. A positioning system including a fiducial marker is placed adjacent to the object to be imaged and held rigidly in place to provide correlation of the location of the region of interest relative to the fiducial marker. A gamma emitting marker is then positioned at the calculated location of the region of interest and imaged to verify that that the calculated position corresponds to the actual location. The positioning system can then be used to accurately position and support any other hardware that needs to be positioned at the region of interest.
摘要翻译：一种用于成像疑似癌症并引导医师去除组织样本用于活组织检查的立体定向伽马引导定位系统。伽马引导定位系统包括三步骤程序，包括定位，相关和验证。定位系统包括具有一组倾斜准直仪的伽马相机，用于产生感兴趣区域的立体图像。将包括基准标记的定位系统放置在与要成像的对象相邻并且刚性地保持就位以提供相对于基准标记的感兴趣区域的位置的相关性。然后将伽马发射标记物定位在所计算的感兴趣区域的位置并成像以验证所计算的位置对应于实际位置。然后可以使用定位系统来精确定位和支持需要定位在感兴趣区域的任何其他硬件。

4. 发明授权

US08489177B2 Fiducial marker and method for gamma guided stereotactic localization 有权
标题翻译：用于伽马引导立体定向定位的基准标记和方法
公开(公告)号：US08489177B2
公开(公告)日：2013-07-16
申请号：US12218576
申请日：2008-07-16
申请人： Benjamin Lawrence Welch
发明人： Benjamin Lawrence Welch
IPC分类号： A61B6/02
CPC分类号： A61B6/022 , A61B6/4258 , A61B6/4291 , A61B34/20 , A61B90/361 , A61B90/37 , A61B90/39 , A61B2090/371 , A61B2090/392
摘要： A fiducial marker for use in a gamma-guided stereotactic localization system for imaging a suspected cancer and guiding a physician in the removal of tissue samples for biopsy. The fiducial marker includes a fiducial source that can be accurately located in a positioning system and used to correlate the location of the positioning system with the detector and therefore the region-of-interest. The fiducial can be made radioactive such that it can be seen by the gamma camera. The fiducial marker enables the accurate positioning of other hardware in proximity to the object to be viewed.
摘要翻译：用于伽马引导立体定位系统的基准标记，用于成像疑似癌症并引导医师去除组织样本用于活检。基准标记包括可准确地定位在定位系统中并用于将定位系统的位置与检测器相关联并因此将感兴趣区域相关联的基准源。基准可以被制成放射性，使其可以被伽马相机看到。基准标记使得可以将其他硬件精确定位在待观察对象附近。

5. 发明申请

US20100016713A1 Fiducial marker and method for gamma guided stereotactic localization 有权
标题翻译：用于伽马引导立体定向定位的基准标记和方法
公开(公告)号：US20100016713A1
公开(公告)日：2010-01-21
申请号：US12218576
申请日：2008-07-16
申请人： Benjamin Lawrence Welch
发明人： Benjamin Lawrence Welch
IPC分类号： A61B5/05
CPC分类号： A61B6/022 , A61B6/4258 , A61B6/4291 , A61B34/20 , A61B90/361 , A61B90/37 , A61B90/39 , A61B2090/371 , A61B2090/392
摘要： A fiducial marker for use in a gamma-guided stereotactic localization system for imaging a suspected cancer and guiding a physician in the removal of tissue samples for biopsy. The fiducial marker includes a fiducial source that can be accurately located in a positioning system and used to correlate the location of the positioning system with the detector and therefore the region-of-interest. The fiducial can be made radioactive such that it can be seen by the gamma camera. The fiducial marker enables the accurate positioning of other hardware in proximity to the object to be viewed.
摘要翻译：用于伽马引导立体定位系统的基准标记，用于成像疑似癌症并引导医师去除组织样本用于活检。基准标记包括可准确地定位在定位系统中并用于将定位系统的位置与检测器相关联并因此将感兴趣区域相关联的基准源。基准可以被制成放射性，使其可以被伽马相机看到。基准标记使得可以将其他硬件精确定位在待观察对象附近。

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