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11. 发明公开

EP0221409A3 Pulse centroid echo method and apparatus for enhanced sound velocity estimation in vivo 失效
标题翻译：脉搏中心ECHO方法和装置，用于增强VIVO中的声速估计
公开(公告)号：EP0221409A3
公开(公告)日：1987-08-12
申请号：EP86114290
申请日：1986-10-15
申请人： BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM
发明人： Ophir, Jonathan
IPC分类号： G01H05/00 , G01S07/52 , G01S15/89 , A61B08/00
CPC分类号： A61B8/00 , G01H5/00 , G01S7/52025 , G01S15/8913
摘要： A method and apparatus of enhancing the accuracy of in vivo sound velocity estimation by identifying segments of different sound velocity along a tracked ultrasound beam. The effects of refraction on the tracked beam at the interface between tissue regions are estimated. Also disclosed is a technique for estimating the refractive effects of naturally occurring and artificially introduced acoustical contrast fluids. The accuracy of the sound velocity measurements is increased by utilizing the centroid-to-centroid distance between the pulses produced by ultrasound sending and receiving transducers in calculating the ultrasound beam velocity.

12. 发明公开

EP0146051A3 Stand-off device with special fluid 失效
标题翻译：具有特殊流体的标准装置
公开(公告)号：EP0146051A3
公开(公告)日：1985-07-31
申请号：EP84114550
申请日：1984-11-30
申请人： Hewlett-Packard Company
发明人： Chen, James N.
IPC分类号： A61B08/00 , G10K11/02
CPC分类号： A61B8/4281 , G10K11/02
摘要： ® A stand-off device for use with acoustic transducers is described having a liquid-filled chamber with a diaphragm portion which can be held against the body of a patient. The diaphragm is of such a thickness that reflections from its diaphragm/body interface (I B ) and reflections from its liquid/diaphragm interface (I L ) tend to cancel one another. The diaphragm material and the liquid (L) in the chamber are selected such that their acoustic impedances ensure cancellation of the reflected waves.

13. 发明申请

WO1998018387A1 INSTRUMENT HAVING ENHANCED ULTRASOUND VISIBILITY 审中-公开
标题翻译：具有增强超声可见性的仪器
公开(公告)号：WO1998018387A1
公开(公告)日：1998-05-07
申请号：PCT/GB1997002935
申请日：1997-10-24
申请人： BRITISH TECHNOLOGY GROUP LIMITED , JOSEPH, Anton, Emmanuel, Arulraj
发明人： BRITISH TECHNOLOGY GROUP LIMITED
IPC分类号： A61B08/00
CPC分类号： A61B8/481 , A61B2090/3925 , A61K49/223
摘要： An instrument (10) for ultrasonic imaging comprises a probe (12) for insertion into a material (62) containing a liquid. The probe (12) has a coating comprising a carrier material (30) and a quantity of reactive material (32) which, upon contacting a reactant produce a quantity of bubbles (62) adjacent the coating for reflecting ultrasonic energy. In one application the probe (12) comprises a biopsy needle and the coating is positioned towards a sharp distal end thereof (14a) thereby to facilitate the guiding and positioning thereof. Alternatively, the coating can be provided along the entire length of the instrument (10) or at descrete portions along its length.
摘要翻译：用于超声波成像的仪器（10）包括用于插入到含有液体的材料（62）中的探针（12）。探针（12）具有包括载体材料（30）和一定量的反应性材料（32）的涂层，其在反应物接触时产生邻近涂层的反射超声波能量的气泡（62）。在一个应用中，探针（12）包括活检针，并且涂层朝向其尖端远端（14a）定位，从而便于其引导和定位。或者，可以沿着仪器（10）的整个长度或沿其长度的分支部分提供涂层。

14. 发明申请

WO1998017178A1 MEASUREMENT OF OBJECT LAYER THICKNESS USING ULTRA-SONIC METHODS AND DEVICES 审中-公开
标题翻译：使用超声波方法和器件测量物体层厚度
公开(公告)号：WO1998017178A1
公开(公告)日：1998-04-30
申请号：PCT/US1997018993
申请日：1997-10-21
申请人： LANG, Philipp , GRAMPP, Stephan , MENDLEIN, John, D.
IPC分类号： A61B08/00
CPC分类号： A61B5/4872 , A61B5/6843 , A61B8/0858 , A61B8/4272
摘要： The present invention provides for a method of measuring layer thickness in an object comprising transmitting at least a first and a second ultra-sonic pulse from at least a first and second position; measuring at least one reflective distance from the first pulse and at least one reflective distance from the second pulse, wherein the reflective distance is from the object's external surface (or probe) to a reflective interface (5) of at least one layer; selecting the reflective distance having the shortest reflective distance to indicate the distance between the external surface (or probe surface) and the reflective interface (5) of at least one layer, wherein the selecting of the shortest reflective distance reduces ultra-sonic transmission parallax of the first and second pulses relative to a plane (4) in the object.
摘要翻译：本发明提供一种测量物体中的层厚度的方法，包括从至少第一和第二位置至少传输第一和第二超声波脉冲; 测量与第一脉冲的至少一个反射距离和距离第二脉冲的至少一个反射距离，其中反射距离是从物体的外表面（或探针）到至少一层的反射界面（5）; 选择具有最短反射距离的反射距离以指示至少一层的外表面（或探针表面）和反射界面（5）之间的距离，其中选择最短反射距离减小超声波透射视差相对于物体中的平面（4）的第一和第二脉冲。

15. 发明申请

WO1997008991A1 ULTRASONIC RECEIVE BEAMFORMER WITH PHASED SUB-ARRAYS 审中-公开
标题翻译：超声波接收带有相位子阵列的波束形成器
公开(公告)号：WO1997008991A1
公开(公告)日：1997-03-13
申请号：PCT/US1996013249
申请日：1996-08-16
申请人： ACUSON CORPORATION
发明人： ACUSON CORPORATION , PETROFSKY, Joseph, G. , MASLAK, Samuel, H. , COLE, Christopher, R.
IPC分类号： A61B08/00
CPC分类号： G01S15/8927 , G01S7/52026 , G01S7/52028 , G01S7/52046 , G01S15/8915 , G01S15/8993 , G01S15/8995 , G10K11/345 , G10K11/346
摘要： An ultrasonic receive beamformer (10) includes transducers (11) forming receive signals that are applied to sub-array processors (12). Each sub-array processor includes at least one analog preconditioning circuit (13), phase shifter (14) and a summer (16), and each phase shifter is responsive to at least one of the transducer signals to shift the transducer signal by a respective phase angle and to apply the phase shifted transducer signals to the summer. Each of the summers supplies a summed sub-array signal via an analog-to-digital converter (18) to a respective beamformer processor (20). The phase angles for any one of the sub-array processors form a sum substantially equal to zero. Furthermore, the phase angles for any one of the sub-array processors are independent of the time delay of the respective digital beam former processor. The time resolution of the time delay of the digital beamformer processors is substantially as fine as the time resolution of the phase angles of the phase shifters. The phase angles of the phase shifters are updated at a slower rate than the focusing update rate of the beamformer processors.
摘要翻译：超声波接收波束形成器（10）包括形成施加到子阵列处理器（12）的接收信号的换能器（11）。每个子阵列处理器包括至少一个模拟预处理电路（13），移相器（14）和加法器（16），并且每个移相器响应于至少一个换能器信号以将换能器信号移位相应的相位角，并将相移的换能器信号应用于夏季。每个夏季通过模数转换器（18）将相加的子阵列信号提供给相应的波束形成器处理器（20）。任何一个子阵列处理器的相位角形成基本上等于零的和。此外，任何一个子阵列处理器的相位角独立于相应的数字波束形成处理器的时间延迟。数字波束形成处理器的时间延迟的时间分辨率基本上与移相器的相位角的时间分辨率一样好。移相器的相位角以比波束形成处理器的聚焦更新速率更慢的速度进行更新。

16. 发明申请

WO1996039938A1 PHASED ARRAY TRANSDUCER DESIGN AND METHOD FOR MANUFACTURE THEREOF 审中-公开
标题翻译：相位阵列传感器设计及其制造方法
公开(公告)号：WO1996039938A1
公开(公告)日：1996-12-19
申请号：PCT/US1996006658
申请日：1996-05-10
申请人： ACUSON CORPORATION
发明人： ACUSON CORPORATION , HANAFY, Amin , MARIAN, Vaughn, R. , PLUGGE, Jay, Sterling
IPC分类号： A61B08/00
CPC分类号： G10K11/345 , Y10T29/42
摘要： This invention is a phased array transducer (50) and a method for the manufacture thereof having a design that allows the array to focus in a near field of interest and a far field of interest. The array (50) includes a plurality of even and odd numbered transducer elements (52, 51) where the even and odd numbered elements (52, 51) have an active region of particular widths. The width (62, 64, 66) of the active region of the odd numbered elements (51) is different than the width (66) of the active region of the even numbered elements (52) so that the odd numbered elements (51) can be used to image in one field of interest, while the even numbered elements (52) can be used to image in another field of interest.
摘要翻译：本发明是一种相控阵变换器（50）及其制造方法，其具有允许阵列聚焦在感兴趣的近场和感兴趣的远场中的设计。阵列（50）包括多个偶数和奇数的换能器元件（52,51），其中偶数和奇数元件（52,51）具有特定宽度的有源区域。奇数元件（51）的有源区域的宽度（62,64,66）不同于偶数元件（52）的有源区域的宽度（66），使得奇数元件（51）可以用于在一个感兴趣的领域中进行图像，而偶数编号的元件（52）可以用于在另一个感兴趣的领域中成像。

17. 发明申请

WO1996003922A1 METHOD AND APPARATUS FOR REAL-TIME, CONCURRENT ADAPTIVE FOCUSING IN AN ULTRASOUND BEAMFORMER IMAGING SYSTEM 审中-公开
标题翻译：在超声波束成像系统中的实时自适应聚焦的方法和装置
公开(公告)号：WO1996003922A1
公开(公告)日：1996-02-15
申请号：PCT/US1995009932
申请日：1995-08-04
申请人： ACUSON CORPORATION
发明人： ACUSON CORPORATION , WRIGHT, J., Nelson , MASLAK, Samuel, H. , LANGDON, Donald, R. , HOLLEY, Gregory, L. , COLE, Christopher, R.
IPC分类号： A61B08/00
CPC分类号： G10K11/346 , G01S7/52049 , G01S7/5209 , G01S7/52095 , G01S15/8918 , G01S15/8927 , G01S15/8977 , G01S15/8979
摘要： A method and an apparatus are provided for dynamic, real time adaptive focussing (600) for ultrasound imaging. Aberration delay correction values, corresponding to an aberration region in an imaged subject, are measured (601) concurrently during B-mode imaging scan lines and updated at the scan line rate. The measured aberration delay correction values (Ek, L, Rk) are then applied concurrently (560) to correct the focus of all transmitted and received ultrasound scan lines, regardless of the imaging mode, scan geometry, or imaging frequencies.
摘要翻译：提供了一种用于超声成像的动态，实时自适应聚焦（600）的方法和装置。在B模式成像扫描线期间同时测量对应于成像对象中的像差区域的像差延迟校正值（601）并以扫描线速率更新。然后，测量的像差延迟校正值（Ek，L，Rk）同时被施加（560）以校正所有发射和接收的超声波扫描线的焦点，而不管成像模式，扫描几何形状或成像频率如何。

18. 发明申请

WO1994018887A1 LOCATING AN INTERVENTIONAL MEDICAL DEVICE BY ULTRASOUND 审中-公开
标题翻译：通过超声定位传统医疗设备
公开(公告)号：WO1994018887A1
公开(公告)日：1994-09-01
申请号：PCT/US1994001752
申请日：1994-02-22
申请人： ECHO CATH, INC.
发明人： ECHO CATH, INC. , GARDINEER, Bayard , VILKOMERSON, David
IPC分类号： A61B08/00
CPC分类号： A61B8/0841 , A61B8/0833
摘要： A VIBER vibrating mechanism (31) is coupled to a cannula or needle (30) and operates to provide flexural vibrations to move the needle (30) and to enable detection via the scanner (22) of the position of a needle within a body of interest by a color ultrasound imaging system (24) having a display (25). The VIBER mechanism exhibits multiple modes of oscillation when energized. The VIBER mechanism is excited to exhibit predetermined oscillations at a given frequency in the X-plane, a predetermined oscillation at another frequency in the Y-plane and another frequency of oscillation in the Z-plane. The frequency of oscillation is a function of the entire system, namely the VIBER mechanism and the tissue. The resonant frequency is preferred as it provides larger vibrational amplitudes. The vibration in the representative planes causes a typical conventional color ultrasound imaging system to display the vibration or movement by means of a color variation.
摘要翻译： VIBER振动机构（31）联接到套管或针（30）并且操作以提供弯曲振动以移动针（30）并且使得能够经由扫描器（22）检测针体内的针的位置由具有显示器（25）的彩色超声成像系统（24）感兴趣。 VIBER机构在通电时表现出多种振荡模式。激励VIBER机构在X平面中的给定频率，在Y平面中的另一频率处的预定振荡和Z平面中的另一振荡频率下呈现预定振荡。振荡频率是整个系统的函数，即VIBER机制和组织。谐振频率是优选的，因为它提供更大的振动振幅。代表性平面中的振动导致典型的常规彩色超声成像系统通过颜色变化来显示振动或运动。

19. 发明申请

WO1994009703A1 SURFACTANT-STABILIZED MICROBUBBLE MIXTURES, PROCESS FOR PREPARING AND METHODS OF USING THE SAME 审中-公开
标题翻译：表面活性剂稳定的微生物混合物，其制备方法及其使用方法
公开(公告)号：WO1994009703A1
公开(公告)日：1994-05-11
申请号：PCT/US1993010562
申请日：1993-11-01
申请人： DREXEL UNIVERSITY
发明人： DREXEL UNIVERSITY , WHEATLEY, Margaret, A. , SHEN, Peng , SINGHAL, Shruti , GOLDBERG, Barry, B.
IPC分类号： A61B08/00
CPC分类号： A61K49/223
摘要： The present invention is a mixture including a solvent, a first surfactant and a second, dispersible surfactant different from the first surfactant, the mixture having stabilized gas microbubbles formed therein by sonication. The gas microbubbles are useful in ultrasonic diagnostics. Preferably the first surfactant is substantially soluble in the solvent and the second surfactant is substantially insoluble in the solvent. The present invention also includes a process for preparing the stabilized gas microbubbles and a method for altering the contrast of an ultrasonic image using the microbubbles as a contrast agent.
摘要翻译：本发明是包含溶剂，第一表面活性剂和不同于第一表面活性剂的第二可分散表面活性剂的混合物，所述混合物通过超声处理在其中形成稳定的气体微泡。气体微泡可用于超声诊断。优选地，第一表面活性剂基本上可溶于溶剂，第二表面活性剂基本上不溶于溶剂。本发明还包括一种制备稳定气体微泡的方法和一种使用微泡作为造影剂改变超声波图像的对比度的方法。

20. 发明申请

WO1994007416A1 MEASUREMENT OF ABSOLUTE VASCULAR FLOW 审中-公开
标题翻译：绝对血管流量测量
公开(公告)号：WO1994007416A1
公开(公告)日：1994-04-14
申请号：PCT/US1993009129
申请日：1993-09-27
申请人： FEIRING, Andrew, J.
IPC分类号： A61B08/00
CPC分类号： A61B8/06 , A61B8/12 , A61B8/445 , G01F1/663
摘要： A vascular flow measurement catheter device for measuring total volumetric flow through a vessel includes a flow measurement catheter (12) having a full flow lumen of known cross-sectional geometry provided with a relatively short distal measurement segment with inlet and outlet ports (20, 24) positioned to carry the full flow of the vessel in the manner of a segment of the vessel itself when the outer catheter (12) is positioned in the vessel of interest. An ultrasonic transducer system (32) is mounted in the flow measurement catheter for communicating the velocity of the fluid in the measurement segment of the full flow lumen and for determining the total volumetric flow. An obturator catheter (16) is provided in coaxial relation to the lumen of the flow measurement catheter and adapted to travel along and within or without the full flow lumen of the measurement catheter to function to shut off the flow through the measurement catheter when advanced over inlet or outlet ports of the measurement catheter.
摘要翻译：用于测量通过血管的总体积流量的血管流量测量导管装置包括流量测量导管（12），该流量测量导管具有已知横截面几何形状的全流动腔，该流体管具有相对较短的远端测量段，其具有入口和出口（20,24 ）定位成当外导管（12）位于感兴趣的容器中时，以容器本身的一段的方式携带容器的全流。超声波换能器系统（32）安装在流量测量导管中，用于传送全流量管的测量段中的流体的速度并用于确定总体积流量。闭塞导管（16）设置成与流量测量导管的内腔同轴，并且适于在测量导管的整个流动腔内和内部或内部行进，以用于在超过测量导管时关闭通过测量导管的流动测量导管的入口或出口。

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