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    • 12. 发明公开
    • IMPLANT WITH SHAPE MEMORY
    • IMPLANTAT MITFORMGEDÄCHTNIS
    • EP1663069A1
    • 2006-06-07
    • EP04765548.5
    • 2004-09-23
    • Angiomed GmbH & Co. Medizintechnik KG
    • BLANK, ThiemoPATHAK, Chandrashekhar, Prabhakar
    • A61F2/06
    • B29C61/00A61F2/82A61F2210/0038A61F2210/0042A61F2210/0047B29C61/02B29L2031/7534
    • An implant having capability to expand and contract radially through a range of diameters, with corresponding changes in the cross-sectional area of the lumen, said implant exhibiting a remembered configuration in which the diameter of the implant is at the low end of said range of diameters, such that the implant is prompted to change its configuration towards said remembered configuration, that is, towards a reduced diameter configuration, upon the imposition on the implant of outside stimulus; said implant being characterised by: a molecule distributed within its bulk volume that preferentially responds to an applied field that permeates said volume, wherein said applied field constitutes the outside stimulus, and the preferential response of the molecule provides the prompt on the implant to change to the said remembered configuration.
    • 植入物具有通过一定范围的直径而径向扩张和收缩的能力,以及腔的横截面面积的相应变化,所述植入物呈现记忆结构,其中植入物的直径处于所述范围的低端 直径,使得植入物被迫将其构型改变成朝向所述记忆构型,即,在施加在外部刺激的植入物上时朝向减小的直径构型; 所述植入物的特征在于:分布在其本体体积内的分子优先响应渗透所述体积的施加的场,其中所述施加的场构成外部刺激,并且分子的优先响应提供植入物上的提示,以改变为 所述记住的配置。
    • 14. 发明申请
    • DEVICES AND METHODS FOR DYNAMIC FOCUSING MOVEMENT
    • 用于动态聚焦运动的装置和方法
    • WO2012092333A1
    • 2012-07-05
    • PCT/US2011/067516
    • 2011-12-28
    • ELENZA, INC.MAZZOCCHI, RudyBLUM, Ronald David
    • MAZZOCCHI, RudyBLUM, Ronald David
    • A61F2/16
    • A61F2/1635A61F2/1629A61F2/1648A61F2002/1681A61F2210/0014A61F2210/0023A61F2210/0033A61F2210/0038A61F2250/0002
    • An implantable ophthalmic device with one or more optical elements coupled to one or more shape-memory members provides dynamically variable optical power to restore lost accommodation in individuals suffering from presbyopia or aphakia. Running current from a power supply through the shape-memory members causes the shape-memory members to heat up. Once the current heats the shape-memory members past a forward phase-transition temperature, the shape-memory members change shape, which, in turn, causes the optical element(s) to move, yielding a corresponding change in effective optical power. Cooling the shape-memory members (e.g., by reducing or stopping the flow of current) below a reverse phase-transition temperature causes the shape-memory members to return to their original shape, which, in turn, restoring the optical element(s) to their original positions and returning the effective optical power to its original level.
    • 具有耦合到一个或多个形状记忆部件的一个或多个光学元件的可植入眼科装置提供动态可变的光学功率,以恢复患有老花眼或无晶状体的个体的失去的适应性。 从电源通过形状记忆部件运行电流导致形状记忆部件加热。 一旦电流加热形状记忆元件超过正向相变温度,则形状记忆元件改变形状,这又导致光学元件移动,产生有效光功率的相应变化。 将形状记忆体(例如,通过减少或停止电流的流动)冷却到反相转变温度以下,导致形状记忆元件返回到其原始形状,这反过来恢复光学元件, 到原来的位置,并将有效光功率恢复到原来的水平。
    • 20. 发明申请
    • Secure stent for maintaining a lumenal opening
    • 用于保持管腔开口的固定支架
    • US20030135268A1
    • 2003-07-17
    • US09547708
    • 2000-04-11
    • Ashvin Desai
    • A61F002/06
    • A61F2/88A61F2/848A61F2/91A61F2/92A61F2/966A61F2210/0033A61F2210/0038A61F2230/005A61F2230/0063A61F2230/0076A61F2230/0078A61L2300/604A61L2300/606
    • A secure stent for maintaining a lumenal opening constructed preferably as a tubular structure of NiTi material or bioabsorbable polymers. The circumference of the tube is preferably in the shape of a polygon in contrast to the circular or oval shape of a body lumen into which the stent is to be placed. The polygon shape and ribs provides interference with the lumen wall and resists stent migration. The diameter of the stent tube is configured with each end enlarged providing flanges for interference with a lumen wall. The central portion of the stent is also bulged out to an increased diameter to provide an enhanced lumen wall resistance to avoid migration. In addition, the locking feature of a ribbed structure prevents the stent from collapsing, and thereby maintains the lumen opening. The stent is preferably constructed from polymers, including bioabsorbable polymers, and/or super elastic materials. The bioabsorbable polymer construction aids removal by causing the tube diameter to collapse. Removal of the stent can therefore be accomplished by simply grasping the proximal end of the stent. Alternatively, a stent constructed entirely of bioabsorbable material will eventually be entirely absorbed, avoiding the need for removal. Alternatively, the stent can be preferably constructed of NiTi or other shape memory material and set in the desired shape at a high temperature. Installation is accomplished by cooling the stent to the malleable Martensite state and winding it on a small diameter mandrel of an insertion/removal tool. The compacted stent is then placed in a probe and inserted in a body lumen, whereupon it is heated to an Austenite state where it regains its spring tension, forcing it back toward the set shape. Removal is accomplished by cooling the stent to the malleable Martensite state and pulling it out. If the selected material is bioabsorbable, the stent generally does not have to be removed.
    • 一种用于保持内窥镜开口的安全支架,优选地构造为NiTi材料或生物可吸收聚合物的管状结构。 与放置支架的体腔的圆形或椭圆形形状相比,管的周长优选为多边形。 多边形形状和肋骨提供与腔壁的干涉并抵抗支架迁移。 支架管的直径被构造成每个端部被扩大,提供用于与腔壁干涉的凸缘。 支架的中心部分也凸起到增加的直径以提供增强的内壁壁阻力以避免迁移。 此外,肋状结构的锁定特征防止支架塌陷,从而保持管腔开口。 支架优选由聚合物构成,包括生物可吸收聚合物和/或超弹性材料。 生物可吸收的聚合物构造有助于通过使管直径崩溃而去除。 因此,可以通过简单地抓住支架的近端来实现支架的移除。 或者,完全由生物可吸收材料构成的支架将最终被完全吸收,避免了移除的需要。 或者,支架可以优选地由NiTi或其它形状记忆材料构成,并且在高温下设置为所需形状。 通过将支架冷却到可延展的马氏体状态并将其卷绕在插入/移除工具的小直径心轴上来实现安装。 然后将压实的支架放置在探针中并插入体腔中,然后将其加热到奥氏体状态,其中恢复其弹簧张力,迫使其回到固定形状。 通过将支架冷却到可延展的马氏体状态并将其拉出来实现去除。 如果所选择的材料是生物可吸收的,则支架通常不必被去除。