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11. 发明授权

US08023732B2 Accelerated image registration by means of parallel processors 有权
标题翻译：通过并行处理器加速图像配准
公开(公告)号：US08023732B2
公开(公告)日：2011-09-20
申请号：US11780971
申请日：2007-07-20
申请人： Yu Deuerling-Zheng , Christian Eisenacher , Adam K. Galant , Joachim Hornegger , Marc Stamminger
发明人： Yu Deuerling-Zheng , Christian Eisenacher , Adam K. Galant , Joachim Hornegger , Marc Stamminger
IPC分类号： G06K9/00
CPC分类号： G06T7/238 , G06T7/32 , G06T7/33 , G06T2200/28 , G06T2207/10116 , G06T2207/30101
摘要： A method is provided for accelerating non-rigid image registration, using parallel processors. To that end, on a commercially available graphics card, a block-matching algorithm is implemented, which, by histogram-based similarity standards, calculates the motion vectors for individual blocks. All the blocks are processed simultaneously and individually. The complete motion vector field is obtained by bilinear interpolation. Optimized search methods, such as conjugate direction searching, are employed. The algorithm terminates once the optimal displacement has been found for all the blocks. The registration is done completely on the graphics card. The algorithm is fully automatic, precise, and fast. The program may be employed for instance in registration for digital subtraction angiography.
摘要翻译：提供了一种使用并行处理器加速非刚性图像配准的方法。为此，在市售的图形卡上，实现了块匹配算法，其通过基于直方图的相似性标准来计算各个块的运动矢量。所有的块被同时和单独处理。通过双线性插值获得完整的运动矢量场。采用优化的搜索方法，如共轭方向搜索。一旦找到所有块的最佳位移，算法就会终止。注册完全在图形卡上完成。该算法全自动，精确，快速。该程序可以用于例如用于数字减影血管造影术的注册。

12. 发明申请

US20150279084A1 Guided Noise Reduction with Streak Removal for High Speed C-Arm CT 审中-公开
标题翻译：引导降噪与高速C臂CT条纹去除
公开(公告)号：US20150279084A1
公开(公告)日：2015-10-01
申请号：US14262277
申请日：2014-04-25
申请人： Yu Deuerling-Zheng , Michael Manhart
发明人： Yu Deuerling-Zheng , Michael Manhart
IPC分类号： G06T15/08 , G06T5/00
CPC分类号： G06T5/002 , G06T5/50 , G06T2207/10081 , G06T2207/30016 , G06T2207/30101
摘要： In order to minimize streak artifacts within reconstructions of perfusion maps generated from moving C-arm acquisitions, a streak reduction method includes threshold analysis, time-contrast curve analysis, and total variation analysis. One or more mask volumes and a plurality of contrast agent enhanced volumes are generated based on a plurality of projections generated using a moving C-arm X-ray device. A maximum contrast attenuation volume is generated based on the plurality of contrast agent enhanced volumes. Voxels are identified as streaks based on analyses applied to the one or more mask volumes, the plurality of contrast agent enhanced volumes, and the maximum contrast attenuation volume, respectively.
摘要翻译：为了最小化移动C臂采集产生的灌注图重构中的条纹伪影，条纹减少方法包括阈值分析，时间对比曲线分析和总体变异分析。基于使用移动的C臂X射线装置产生的多个投影来生成一个或多个掩模体积和多个造影剂增强体积。基于多个造影剂增强体积产生最大对比度衰减体积。基于分别应用于一个或多个掩模体积，多个造影剂增强体积和最大对比度衰减体积的体素，将体素识别为条纹。

13. 发明申请

US20110282193A1 METHOD AND APPARATUS FOR SELECTIVE INTERNAL RADIATION THERAPY PLANNING AND IMPLEMENTATION 有权
标题翻译：选择性内部辐射治疗方法和装置的设计与实现
公开(公告)号：US20110282193A1
公开(公告)日：2011-11-17
申请号：US12777575
申请日：2010-05-11
申请人： Jessica Amberg , Yu Deuerling-Zheng , Sigrid Ferschel , Stefan Lautenschlaeger , Oliver Meissner
发明人： Jessica Amberg , Yu Deuerling-Zheng , Sigrid Ferschel , Stefan Lautenschlaeger , Oliver Meissner
IPC分类号： A61B6/00 , A61M36/00
CPC分类号： A61B6/4441 , A61B6/12 , A61B6/4458 , A61B6/481 , A61B6/487 , A61B6/504 , A61B6/5217 , G06F19/00 , G06F19/321 , G06F19/3468 , G06F19/3481
摘要： In a method and system for planning and implementing a selective internal radiation therapy (SIRT), the liver volume and the tumor volume are automatically calculated in a processor by analysis of items segmented from images obtained from the patient using one or more imaging modalities, with the administration of contrast agent. In the processor, the volume of therapeutic agent that is necessary to treat the tumor is automatically calculated from the liver volume, the tumor volume, and the body surface area of the patient and the lung shunt percentage for the patient. The segmented tumor, as well as segmented feeder vessels are overlaid on a live fluoroscopic image of the patient during SIRT, to assist in positioning a catheter for administering the therapeutic agent, which is then administered according to the calculated volume. The therapeutic agent can be administered via respective feeder vessels in respectively different amounts that correspond to the percentage of blood supply to the tumor from the respective feeder vessels, this distribution also being automatically calculated by analysis of one or more parenchymal blood volume (PBV) images.
摘要翻译：在用于规划和实施选择性内部放射治疗（SIRT）的方法和系统中，通过使用一个或多个成像模式通过分析从患者获得的图像分割的项目，在处理器中自动计算肝体积和肿瘤体积，造影剂的给药。在处理器中，根据患者的肝体积，肿瘤体积和体表面积以及患者的肺分流百分比自动计算治疗肿瘤所需治疗剂的体积。在SIRT期间，分段的肿瘤以及分段的饲养管被覆盖在患者的活透镜图像上，以帮助定位用于施用治疗剂的导管，然后根据计算的体积施用该导管。治疗剂可以通过相应的饲养容器以不同的量施用，这些量对应于来自各个饲养细胞的向肿瘤供血的百分比，该分布也通过分析一个或多个实质血容量（PBV）图像而自动计算。

14. 发明授权

US08738115B2 Method and apparatus for selective internal radiation therapy planning and implementation 有权
标题翻译：选择性内部放射治疗计划和实施的方法和装置
公开(公告)号：US08738115B2
公开(公告)日：2014-05-27
申请号：US12777575
申请日：2010-05-11
申请人： Jessica Amberg , Yu Deuerling-Zheng , Sigrid Ferschel , Stefan Lautenschlaeger , Oliver Meissner
发明人： Jessica Amberg , Yu Deuerling-Zheng , Sigrid Ferschel , Stefan Lautenschlaeger , Oliver Meissner
IPC分类号： A61B5/05
CPC分类号： A61B6/4441 , A61B6/12 , A61B6/4458 , A61B6/481 , A61B6/487 , A61B6/504 , A61B6/5217 , G06F19/00 , G06F19/321 , G06F19/3468 , G06F19/3481
摘要： In a method and system for planning and implementing a selective internal radiation therapy (SIRT), the liver volume and the tumor volume are automatically calculated in a processor by analysis of items segmented from images obtained from the patient using one or more imaging modalities, with the administration of a contrast agent. The volume of therapeutic agent that is necessary to treat the tumor is automatically calculated from the liver volume, the tumor volume, and the body surface area of the patient and the lung shunt percentage for the patient. The therapeutic agent can be administered via respective feeder vessels in respectively different amounts that correspond to the percentage of blood supply to the tumor from the respective feeder vessels, this distribution also being automatically calculated by analysis of one or more parenchymal blood volume (PBV) images.
摘要翻译：在用于规划和实施选择性内部放射治疗（SIRT）的方法和系统中，通过使用一个或多个成像模式通过分析从患者获得的图像分割的项目，在处理器中自动计算肝体积和肿瘤体积，给药造影剂。根据患者的肝体积，肿瘤体积和体表面积以及患者的肺分流百分比自动计算治疗肿瘤所需治疗剂的体积。治疗剂可以通过相应的饲养容器以不同的量施用，这些量对应于来自各个饲养细胞的向肿瘤供血的百分比，该分布也通过分析一个或多个实质血容量（PBV）图像而自动计算。

15. 发明申请

US20140126685A1 ANGIOGRAPHIC EXAMINATION METHOD 审中-公开
标题翻译：放射学检查方法
公开(公告)号：US20140126685A1
公开(公告)日：2014-05-08
申请号：US14014608
申请日：2013-08-30
申请人： Yu Deuerling-Zheng , Michael Manhart
发明人： Yu Deuerling-Zheng , Michael Manhart
IPC分类号： A61B5/00
CPC分类号： A61B5/0033 , A61B6/4441 , A61B6/4458 , A61B6/4464 , A61B6/481 , A61B6/487 , A61B6/504 , A61B6/507 , G06T11/006 , G06T2211/404 , G06T2211/424
摘要： An angiographic examination method for examining an organ, vascular system or other regions of a patient is proposed. Projection images are acquired by an angiography system having an X-ray tube assembly and an X-ray image detector applied to ends of a C-arm, a patient table having a tabletop for carrying the patient, a system control unit, an imaging system and a monitor. Projection images are generated by rotational angiography from a plurality of projection angles. The projection images are subjected to a pre-processing of an FDK reconstruction, the result of which is filtered by a noise-reduction method. A predetermined number of dynamic, iterative reconstruction steps is carried out. Time attenuation curves are reconstructed, which are modeled with a weighted sum of linear basis functions.
摘要翻译：提出了一种用于检查器官，血管系统或患者其他区域的血管造影检查方法。投影图像由具有X射线管组件和X射线图像检测器的血管造影系统获取，该X射线管组件和X射线图像检测器应用于C-臂的末端，具有用于携带患者的桌面的患者台，系统控制单元，成像系统和监视器。通过旋转血管造影从多个投影角度产生投影图像。对投影图像进行FDK重构的预处理，其结果被噪声降低方法滤波。执行预定数量的动态迭代重建步骤。时间衰减曲线被重建，其用线性基函数的加权和建模。

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