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    • 16. 发明授权
    • Microelectronic axon processor
    • 微电子轴突处理器
    • US4632116A
    • 1986-12-30
    • US826940
    • 1986-02-06
    • Joseph M. RosenMorton Grosser
    • Joseph M. RosenMorton Grosser
    • A61B17/11A61F2/02A61B19/00
    • A61F2/02A61B17/1128
    • Normal nerve function is restored across severed ends of a nerve fascicle by inserting between the severed ends a laminated chip perforated with an array of holes each sized to accommodate approximately one axon and each containing at least two electrically conductive regions in ohmic contact with the inner surface of the hole at discrete locations along the axial direction of the hole. Proximal axon segments are permitted to propagate through the holes to join distal segments in random fashion and to be in contact with each of the two electrical contacts. Each contact is part of a circuit pattern capable of monitoring impulses, applying blocking potentials and placing selected pairs of proximal and distal axon segments in electrical contact such that nerve impulses can be routed as desired to restore normal nerve impulse communication and hence nerve function.
    • 通过在切断的端部之间插入穿过孔阵列的层叠芯片,每个尺寸适于容纳大约一个轴突并且每个轴承包含至少两个与内表面欧姆接触的导电区域,从而恢复神经束的切断末端的正常神经功能 的孔沿着孔的轴向的离散位置。 允许近端轴突段以穿过孔的方式传播,以随机的方式连接远端段,并与两个电触点中的每一个接触。 每个触点是能够监视脉冲,施加阻塞电位并且将选定的一对近端和远端轴突段置于电接触中的电路图案的一部分,使得神经脉冲可以根据需要被路由以恢复正常的神经冲动通信并因此恢复神经功能。